catalog number :
MBS013604
products type :
ELISA Kit
products full name :
Canine Cluster of Differentiation 109 ELISA Kit
products short name :
[Cluster of Differentiation 109]
other names :
[CD109 antigen isoform 3; CD109 antigen; CD109 antigen; p180; r150; Gov platelet alloantigens; activated T-cell marker CD109; platelet-specific Gov antigen; 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD109 molecule; 150 kDa TGF-beta-1-binding protein; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; Platelet-specific Gov antigen; p180; r150]
products gene name :
[CD109]
other gene names :
[CD109; CD109; CPAMD7; RP11-525G3.1; CPAMD7]
uniprot entry name :
CD109_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CD109 (hereafter termed "analyte") in undiluted original Canine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001153060.1
ncbi gb acc num :
NM_001159588.1
ncbi mol weight :
161,689 Da
ncbi summary :
This gene encodes a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]
uniprot summary :
CD109: Modulates negatively TGFB1 signaling in keratinocytes. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 6q13. Cellular Component: extracellular space; cell surface; plasma membrane. Molecular Function: serine-type endopeptidase inhibitor activity; transforming growth factor beta binding. Biological Process: negative regulation of protein amino acid phosphorylation; hair follicle development; negative regulation of transforming growth factor beta receptor signaling pathway; regulation of keratinocyte differentiation
size4 :
10x96-Strip-Wells