catalog number :
MBS013584
products type :
ELISA Kit
products full name :
Monkey Prostaglandin Endoperoxide Synthase 1 ELISA Kit
products short name :
[Prostaglandin Endoperoxide Synthase 1]
other names :
[prostaglandin-endoperoxide synthase 1; Prostaglandin G/H synthase 1; prostaglandin G/H synthase 1; PGH synthase 1; cyclooxygenase-1; prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1]
products gene name :
[PTGS1]
other gene names :
[PTGS1; PTGS1; COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1; COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1]
uniprot entry name :
PGH1_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of PTGIR (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
AAL33601.1
ncbi mol weight :
68,686 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (685553); Arachidonic Acid Metabolism Pathway (366); Biological Oxidations Pathway (105698); C20 Prostanoid Biosynthesis Pathway (545299); COX Reactions Pathway (105711); Eicosanoid Synthesis Pathway (198888); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Phase 1 - Functionalization Of Compounds Pathway (105699)
ncbi summary :
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
uniprot summary :
COX-1: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Homodimer. Belongs to the prostaglandin G/H synthase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid Metabolism - arachidonic acid; Oxidoreductase; EC 1.14.99.1. Chromosomal Location of Human Ortholog: 9q32-q33.3. Cellular Component: endoplasmic reticulum membrane; photoreceptor outer segment; intracellular membrane-bound organelle; cytoplasm; nucleus. Molecular Function: prostaglandin-endoperoxide synthase activity; peroxidase activity; dioxygenase activity; metal ion binding; heme binding. Biological Process: xenobiotic metabolic process; regulation of blood pressure; cyclooxygenase pathway; arachidonic acid metabolic process; lipid metabolic process; response to oxidative stress; prostaglandin biosynthetic process; inflammatory response; regulation of cell proliferation
size4 :
10x96-Strip-Wells