catalog number :
MBS012540
products type :
ELISA Kit
products full name :
Mouse Pulmonary Surfactant Associated Protein D ELISA Kit
products short name :
Pulmonary Surfactant Associated Protein D
other names :
pulmonary surfactant-associated protein D; Pulmonary surfactant-associated protein D; pulmonary surfactant-associated protein D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4; surfactant protein D; Collectin-7; Lung surfactant protein D
other gene names :
SFTPD; SFTPD; SP-D; PSP-D; SFTP4; COLEC7; COLEC7; PSPD; SFTP4; PSP-D; SP-D
uniprot entry name :
SFTPD_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 31.2 ng/ml - 1000 ng/ml. Sensitivity: 5.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SPD (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_003010.4
ncbi gb acc num :
NM_003019.4
ncbi mol weight :
37,728 Da
ncbi pathways :
FOXA1 Transcription Factor Network Pathway (137979); Phagosome Pathway (153910); Phagosome Pathway (153859); Regulation Of Retinoblastoma Protein Pathway (137916)
ncbi summary :
The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]
uniprot summary :
SFTPD: Contributes to the lung s defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 10q22.2-q23.1. Cellular Component: proteinaceous extracellular matrix; extracellular space; collagen; endocytic vesicle; lysosome; extracellular region. Molecular Function: protein binding; carbohydrate binding. Biological Process: receptor-mediated endocytosis; negative regulation of T cell proliferation; positive regulation of phagocytosis; defense response to bacterium; negative regulation of interleukin-2 biosynthetic process; innate immune response; respiratory gaseous exchange; surfactant homeostasis; alveolus development; macrophage chemotaxis; regulation of cytokine production