catalog number :
MBS011265
products type :
ELISA Kit
products full name :
Goat Acyl Ghrelin ELISA Kit
products short name :
Acyl Ghrelin
other names :
acyl-protein thioesterase 1 isoform 6; Acyl-protein thioesterase 1; acyl-protein thioesterase 1; lysoPLA I; lysophospholipid-specific lysophospholipase; lysophospholipase I; Lysophospholipase 1; Lysophospholipase I
products gene name :
A-GHR
other gene names :
LYPLA1; LYPLA1; APT1; LPL1; APT-1; LPL-I; hAPT1; APT1; LPL1; APT-1; hAPT1; LPL-I; LysoPLA I
uniprot entry name :
LYPA1_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich
ncbi acc num :
NP_001266289.1
ncbi gb acc num :
NM_001279360.1
ncbi mol weight :
24,670 Da
ncbi pathways :
Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolism Pathway (477135); Metabolism Of Nitric Oxide Pathway (106222); ENOS Activation Pathway (106224); ENOS Activation And Regulation Pathway (106223)
ncbi summary :
This gene encodes a member of the alpha/beta hydrolase superfamily. The encoded protein functions as a homodimer, exhibiting both depalmitoylating as well as lysophospholipase activity, and may be involved in Ras localization and signaling. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 4, 6, and 7. [provided by RefSeq, Jul 2013]
uniprot summary :
LYPLA1: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity and also low lysophospholipase activity. Belongs to the AB hydrolase 2 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Phospholipase; EC 3.1.2.-; Lipid Metabolism - glycerophospholipid. Chromosomal Location of Human Ortholog: 8q11.23. Cellular Component: mitochondrion; cytosol. Molecular Function: palmitoyl-(protein) hydrolase activity; lysophospholipase activity. Biological Process: negative regulation of Golgi to plasma membrane protein transport; regulation of nitric-oxide synthase activity; fatty acid metabolic process; nitric oxide metabolic process; protein depalmitoylation