catalog number :
MBS010472
products type :
ELISA Kit
products full name :
Human Hyaluronidase ELISA Kit
products short name :
Hyaluronidase
other names :
hyaluronidase; Hyaluronidase-3; hyaluronidase-3; lung carcinoma protein 3; hyaluronoglucosaminidase 3; Hyaluronoglucosaminidase-3; Lung carcinoma protein 3
products gene name :
HAASE
other gene names :
HYAL3; HYAL3; LUCA3; HYAL-3; LUCA-3; LUCA3; Hyal-3; LuCa-3
uniprot entry name :
HYAL3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 15.6 ng/ml - 500 ng/ml. Sensitivity: 2.0 ng/ml. Assay Type: Sandwich
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HAASE (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
AAC70915.1
ncbi mol weight :
46,501 Da
ncbi pathways :
Chondroitin Sulfate Degradation Pathway (413376); Chondroitin Sulfate Degradation Pathway (468247); Dermatan Sulfate Degradation Pathway (413375); Dermatan Sulfate Degradation Pathway (468240); Glycosaminoglycan Degradation Pathway (82981); Glycosaminoglycan Degradation Pathway (355)
ncbi summary :
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]
uniprot summary :
HYAL3: a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]. Protein type: Secreted, signal peptide; EC 3.2.1.35; Secreted; Hydrolase. Chromosomal Location of Human Ortholog: 3p21.3. Cellular Component: lysosome; extracellular region; cytoplasmic vesicle. Molecular Function: viral receptor activity; hyaluronoglucuronidase activity; hyalurononglucosaminidase activity. Biological Process: response to antibiotic; cartilage development; response to virus; carbohydrate metabolic process; inflammatory response; hyaluronan catabolic process