catalog number :
MBS009906
products type :
ELISA Kit
products full name :
Human Pulmonary Surfactant Associated Protein D ELISA Kit
products short name :
Pulmonary Surfactant Associated Protein D
other names :
pulmonary surfactant-associated protein D; Pulmonary surfactant-associated protein D; pulmonary surfactant-associated protein D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4; surfactant protein D; Collectin-7; Lung surfactant protein D
other gene names :
SFTPD; SFTPD; SP-D; PSP-D; SFTP4; COLEC7; COLEC7; PSPD; SFTP4; PSP-D; SP-D
uniprot entry name :
SFTPD_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Detection Range: The detection range of this kit is 6.25ng/ml-200ng/ml.
other info2 :
Sensitivity: The sensitivity of this kit is 1.0ng/ml. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SPD (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_003010.4
ncbi gb acc num :
NM_003019.4
ncbi mol weight :
37,728 Da
ncbi pathways :
FOXA1 Transcription Factor Network Pathway 137979!!Phagosome Pathway 153910!!Phagosome Pathway 153859!!Regulation Of Retinoblastoma Protein Pathway 137916
uniprot summary :
Function: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Subunit structure: Oligomeric complex of 4 set of homotrimers. Subcellular location: Secreted extracellular space extracellular matrix. Secreted extracellular space surface film. Post-translational modification: The N-terminus is blocked.Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates . By similarity. Miscellaneous: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C). Sequence similarities: Belongs to the SFTPD family.Contains 1 C-type lectin domain.Contains 1 collagen-like domain.