product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Horse Desmoglein 1 ELISA Kit
catalog :
MBS009789
quantity :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS009789
products type :
ELISA Kit
products full name :
Horse Desmoglein 1 ELISA Kit
products short name :
Desmoglein 1
other names :
desmoglein-1 preproprotein; Desmoglein-1; desmoglein-1; DGI; cadherin family member 4; desmosomal glycoprotein 1; pemphigus foliaceus antigen; desmoglein 1; Cadherin family member 4; Desmosomal glycoprotein 1; DG1; DGI; Pemphigus foliaceus antigen
products gene name :
DSG1
other gene names :
DSG1; DSG1; DG1; DSG; CDHF4; PPKS1; SPPK1; CDHF4; DG1; DGI
uniprot entry name :
DSG1_HUMAN
reactivity :
Horse
storage stability :
Store all reagents at 2-8 degree C
other info1 :
ELISA Type: Sandwich
ncbi gi num :
119703744
ncbi acc num :
NP_001933.2
ncbi gb acc num :
NM_001942.2
uniprot acc num :
Q02413
ncbi mol weight :
113,748 Da
ncbi pathways :
Apoptosis Pathway 105648!!Apoptotic Cleavage Of Cell Adhesion Proteins Pathway 105680!!Apoptotic Cleavage Of Cellular Proteins Pathway 105678!!Apoptotic Execution Phase Pathway 105677!!Staphylococcus Aureus Infection Pathway 172846!!Staphylococcus Aureus Infection Pathway 171867
ncbi summary :
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Subunit structure: Binds to JUP/plakoglobin. Ref.6. Subcellular location: Cell membrane; Single-pass type I membrane protein . By similarity. Cell junction desmosome. Tissue specificity: Epidermis, tongue, tonsil and esophagus. Domain: Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain . By similarity. Involvement in disease: Keratoderma, palmoplantar, striate 1 (SPPK1) [MIM:148700]: A dermatological disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.4. Sequence similarities: Contains 4 cadherin domains.
size :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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