Horse Leucyl-Cystinyl Aminopeptidase ELISA Kit | MyBioSource MBS009591 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Horse Leucyl-Cystinyl Aminopeptidase ELISA Kit

catalog :

MBS009591

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS009591

products type :

ELISA Kit

products full name :

Horse Leucyl-Cystinyl Aminopeptidase ELISA Kit

products short name :

Leucyl-Cystinyl Aminopeptidase

other names :

leucyl-cystinyl aminopeptidase isoform 1; Leucyl-cystinyl aminopeptidase; leucyl-cystinyl aminopeptidase; otase; oxytocinase; vasopressinase; AT (4) receptor; angiotensin IV receptor; insulin-regulated aminopeptidase; placental leucine aminopeptidase; insulin-responsive aminopeptidase; insulin-regulated membrane aminopeptidase; leucyl/cystinyl aminopeptidase; Insulin-regulated membrane aminopeptidase; Insulin-responsive aminopeptidase; IRAP; Oxytocinase; OTase; Placental leucine aminopeptidase

products gene name :

LNPEP

other gene names :

LNPEP; LNPEP; CAP; IRAP; PLAP; P-LAP; OTASE; Cystinyl aminopeptidase; IRAP; OTase; P-LAP

uniprot entry name :

LCAP_HUMAN

reactivity :

Horse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Horse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 6.25 U/L - 200 U/L. Sensitivity: 1.0 U/L.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LNPEP (hereafter termed "analyte") in undiluted original Horse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

61742777

ncbi acc num :

NP_005566.2

ncbi gb acc num :

NM_005575.2

uniprot acc num :

Q9UIQ6

ncbi mol weight :

117,349 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Antigen Processing-Cross Presentation Pathway (477122); Antigen Processing: Ubiquitination Proteasome Degradation Pathway (366162); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Endosomal/Vacuolar Pathway (477125); Immune System Pathway (106386); Insulin-mediated Glucose Transport Pathway (137981); Membrane Trafficking Pathway (106160); Renin-angiotensin System Pathway (83075); Renin-angiotensin System Pathway (486)

ncbi summary :

This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

uniprot summary :

IRAP: a leucyl/cystinyl aminopeptidase. A type II membrane protein and secreted. Resides in intracellular vesicles together with GLUT4 and can then translocate to the cell surface in response to insulin and/or oxytocin. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain. Three alternatively spliced isoforms have been described. Protein type: EC 3.4.11.3; Protease; Membrane protein, integral. Chromosomal Location of Human Ortholog: 5q15. Cellular Component: cytoplasmic vesicle membrane; membrane; lysosomal membrane; integral to plasma membrane; perinuclear region of cytoplasm; extracellular region; plasma membrane; intracellular; cytosol. Molecular Function: zinc ion binding; metallopeptidase activity; aminopeptidase activity. Biological Process: antigen processing and presentation of peptide antigen via MHC class I; protein polyubiquitination; cell-cell signaling; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent; antigen processing and presentation of exogenous peptide antigen via MHC class I; protein catabolic process; female pregnancy; proteolysis

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage