catalog number :
MBS009350
products type :
ELISA Kit
products full name :
Human Pituitary Adenylate Cyclase Activating Polypeptide Receptor 1 ELISA Kit
products short name :
Pituitary Adenylate Cyclase Activating Polypeptide Receptor 1
other names :
pituitary adenylate cyclase-activating polypeptide type I receptor isoform 5; Pituitary adenylate cyclase-activating polypeptide type I receptor; pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R-1; PACAP-R-1A; PACAP type I receptor; PACAP type IA receptor; adenylate cyclase activating polypeptide 1 type 1 receptor; pituitary adenylate cyclase activating polypeptide receptor; pituitary adenylate cyclase activating polypeptide 1 receptor (1); pituitary adenylate cyclase-activating polypeptide type IA receptor; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; adenylate cyclase activating polypeptide 1 receptor 1
products gene name :
PACAPR1
other gene names :
Adcyap1r1; Adcyap1r1; PAC1-R; PACAPR1; PACAP-R1; PACAPR1A; PACAP-R1A; PACAP type I receptor; PACAP-R-1; PACAP-R1
uniprot entry name :
PACR_RAT
specificity :
No significant cross-reactivity or interference between Human PACAPR1 and analogues was observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intended Uses: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate PACAPR1 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]
products description :
Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate PACAPR1 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!
ncbi acc num :
NP_001257511.1
ncbi gb acc num :
NM_001270582.1
ncbi mol weight :
59,637 Da
ncbi pathways :
Activation Of TRKA Receptors Pathway (828151); Circadian Entrainment Pathway (698787); Circadian Entrainment Pathway (699872); Class B/2 (Secretin Family Receptors) Pathway (828240); G Alpha (s) Signalling Events Pathway (828245); GPCR Downstream Signaling Pathway (828244); GPCR Ligand Binding Pathway (828214); GPCRs, Class B Secretin-like Pathway (198460); Glucagon-type Ligand Receptors Pathway (828242); Insulin Secretion Pathway (777547)
ncbi summary :
regulates neural precursor proliferation; mediates inhibitory signaling for Shh-induced cerebellar granule precursor cell proliferation [RGD, Feb 2006]
uniprot summary :
ADCYAP1R1: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Belongs to the G-protein coupled receptor 2 family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2. Cellular Component: Golgi membrane; neuron projection; tight junction; cell surface; rough endoplasmic reticulum; cytoplasm; integral to membrane; caveola; receptor complex; endosome. Molecular Function: neuropeptide binding; ADP-ribosylation factor binding; vasoactive intestinal polypeptide receptor activity; adenylate cyclase binding. Biological Process: response to drug; development of primary female sexual characteristics; G-protein coupled receptor protein signaling pathway; cAMP-mediated signaling; response to ethanol; phospholipase C activation; positive regulation of cAMP biosynthetic process; spermatogenesis; cell differentiation; multicellular organismal response to stress; response to estradiol stimulus