catalog number :
MBS009257
products type :
ELISA Kit
products full name :
Human 12-Lipoxygenase ELISA Kit
products short name :
12-Lipoxygenase
other names :
12-lipoxygenase, partial; Arachidonate 15-lipoxygenase; arachidonate 15-lipoxygenase; 15-LOX; 15-lipooxygenase-1; arachidonate omega-6 lipoxygenase; arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase
products gene name :
LOX-12
other gene names :
ALOX15; ALOX15; 15LOX-1; 15-LOX-1; LOG15; 15-LOX
uniprot entry name :
LOX15_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LOX-12 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LOX-12 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
ncbi acc num :
AAA35482.1
ncbi mol weight :
74,804 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (685553); Arachidonic Acid Metabolism Pathway (366); Eicosanoid Synthesis Pathway (198888); IL4-mediated Signaling Events Pathway (137933); Linoleic Acid Metabolism Pathway (82992); Linoleic Acid Metabolism Pathway (367); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); Serotonergic Synapse Pathway (525336)
uniprot summary :
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family. Protein type: Lipid Metabolism - linoleic acid; Oxidoreductase; EC 1.13.11.33; Lipid Metabolism - arachidonic acid; Motility/polarity/chemotaxis; EC 1.13.11.31. Chromosomal Location of Human Ortholog: 17p13.3. Cellular Component: extrinsic to internal side of plasma membrane; membrane; plasma membrane; lipid particle; cytosol. Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; arachidonate 12-lipoxygenase activity; hepoxilin A3 synthase activity; protein binding; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding. Biological Process: ossification; positive regulation of heterotypic cell-cell adhesion; positive regulation of actin filament polymerization; wound healing; lipoxygenase pathway; negative regulation of adaptive immune response; phosphatidylethanolamine biosynthetic process; arachidonic acid metabolic process; leukotriene metabolic process; hepoxilin biosynthetic process; inflammatory response; bone mineralization; apoptotic cell clearance