catalog number :
MBS009136
products type :
ELISA Kit
products full name :
Human Bone Morphogenetic Protein 6 ELISA Kit
products short name :
Bone Morphogenetic Protein 6
other names :
bone morphogenetic protein 6 preproprotein; Bone morphogenetic protein 6; bone morphogenetic protein 6; BMP-6; VGR-1; VG-1-R; VG-1-related protein; Vg1-related sequence; vegetal-related (TGFB related) cytokine; vegetal related growth factor (TGFB-related); bone morphogenetic protein 6; VG-1-related protein
products gene name :
BMP6
other gene names :
BMP6; BMP6; VGR; VGR1; VGR; BMP-6; VG-1-R; VGR-1
uniprot entry name :
BMP6_HUMAN
specificity :
No significant cross-reactivity or interference between Human BMP6 and analogues was observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids. Intended Uses: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate BMP6 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications. !Detection Range: The detection range of this kit is 0.625-20ng/ml.
other info2 :
Sensitivity: The sensitivity of this kit is 0.1ng/ml. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]
products description :
Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate BMP6 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic or diagnostic applications!
ncbi acc num :
NP_001709.1
ncbi gb acc num :
NM_001718.4
ncbi mol weight :
57,226 Da
ncbi pathways :
BMP Receptor Signaling Pathway 137948!!Endochondral Ossification Pathway 198812!!Hippo Signaling Pathway 749777!!Hippo Signaling Pathway 750388!!Id Signaling Pathway 198871!!Ovarian Steroidogenesis Pathway 790011!!Ovarian Steroidogenesis Pathway 795173!!TGF-beta Signaling Pathway 83064!!TGF-beta Signaling Pathway 475
ncbi summary :
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Induces cartilage and bone formation. Subunit structure: Interacts with SOSTDC1 . By similarity. Subcellular location: Secreted . By similarity. Sequence similarities: Belongs to the TGF-beta family.