catalog number :
MBS007855
products type :
ELISA Kit
products full name :
Human Attractin ELISA Kit
products short name :
[Attractin]
other names :
[attractin isoform 2 preproprotein; Attractin; attractin; attractin-2; mahogany homolog; mahogany protein; attractin; DPPT-L; Mahogany homolog]
products gene name :
[ATRN]
other gene names :
[ATRN; ATRN; MGCA; DPPT-L; KIAA0548; MGCA]
uniprot entry name :
ATRN_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ATRN (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_647538.1
ncbi gb acc num :
NM_139322.2
ncbi mol weight :
158,537 Da
ncbi summary :
Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, May 2011]
uniprot summary :
ATRN: Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: extracellular space; integral to plasma membrane; cytoplasm; plasma membrane. Molecular Function: receptor activity; carbohydrate binding. Biological Process: myelination; pigmentation; regulation of multicellular organism growth; cerebellum development; response to oxidative stress; inflammatory response
size4 :
10x96-Strip-Wells