This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Cavy Complement Factor D ELISA Kit
catalog :
MBS007607
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS007607
products type :
ELISA Kit
products full name :
Cavy Complement Factor D ELISA Kit
products short name :
[Complement Factor D]
other names :
[complement factor D preproprotein; Complement factor D; complement factor D; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); complement factor D (adipsin); Adipsin; C3 convertase activator; Properdin factor D]
products gene name :
[CFD]
other gene names :
[CFD; CFD; DF; ADN; PFD; ADIPSIN; DF; PFD]
uniprot entry name :
CFAD_HUMAN
reactivity :
Cavy
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ug/ml - 8 ug/ml. Sensitivity: 0.1 ug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CFD (hereafter termed "analyte") in undiluted original Cavy body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
42544239
ncbi acc num :
NP_001919.2
ncbi gb acc num :
NM_001928.2
uniprot acc num :
P00746
ncbi mol weight :
27,033 Da
ncbi pathways :
Adipogenesis Pathway (198832); Alternative Complement Activation Pathway (106410); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Complement Cascade Pathway (106405); Hemostasis Pathway (106028); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Platelet Activation, Signaling And Aggregation Pathway (106034)
ncbi summary :
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [provided by RefSeq, Jul 2008]
uniprot summary :
CFD: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Defects in CFD are the cause of complement factor D deficiency (CFDD). CFDD is an immunologic disorder characterized by increased susceptibility to bacterial infections, particularly Neisseria infections, due to a defect in the alternative complement pathway. Belongs to the peptidase S1 family. Protein type: Protease; Secreted, signal peptide; EC 3.4.21.46; Secreted. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: extracellular space; extracellular region. Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity. Biological Process: platelet activation; platelet degranulation; complement activation, alternative pathway; innate immune response; blood coagulation; proteolysis; complement activation. Disease: Complement Factor D Deficiency
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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