catalog number :
MBS006925
products type :
ELISA Kit
products full name :
Fish Ccaat/Enhancer Binding Protein Beta ELISA Kit
products short name :
[Ccaat/Enhancer Binding Protein Beta]
other names :
[CCAAT/enhancer-binding protein beta; CCAAT/enhancer-binding protein beta; CCAAT/enhancer-binding protein beta; TCF-5; nuclear factor NF-IL6; transcription factor 5; nuclear factor of interleukin 6; interleukin 6-dependent DNA-binding protein; liver-enriched transcriptional activator protein; CCAAT/enhancer binding protein (C/EBP), beta; Liver activator protein; Nuclear factor NF-IL6; Transcription factor 5]
products gene name :
[C/EBPbeta]
other gene names :
[CEBPB; CEBPB; LAP; CRP2; TCF5; IL6DBP; NF-IL6; C/EBP-beta; LAP; TCF5; C/EBP beta; TCF-5]
uniprot entry name :
CEBPB_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CEBPB (hereafter termed "analyte") in undiluted original Fish body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_005185.2
ncbi gb acc num :
NM_005194.3
ncbi mol weight :
36,106 Da
ncbi pathways :
Adipogenesis Pathway (198832); C-MYB Transcription Factor Network Pathway (138073); Developmental Biology Pathway (477129); Diurnally Regulated Genes With Circadian Orthologs Pathway (198813); EGFR1 Signaling Pathway (198782); FOXA1 Transcription Factor Network Pathway (137979); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); IFN-gamma Pathway (138040); IL-6 Signaling Pathway (198864); IL4-mediated Signaling Events Pathway (137933)
ncbi summary :
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq, Jul 2008]
uniprot summary :
C/EBP-beta: a bZIP transcription factor which can form homodimers or heterodimers with the related proteins CEBP-alpha, -delta and -gamma. Involved in immune and inflammatory responses. Specifically binds to regulatory regions of genes encoding IL-6, other cytokines and several acute-phase proteins. There are two forms of C/EBPbeta, the 38kDa liver activating protein (LAP) and the 20kDa liver inhibitory protein (LIP) which may be products of alternative translation. LAP is a transcriptional activator while LIP may inhibit C/EBPbeta transcriptional activity. Phosphorylated and activated by ERK1/2. Protein type: Motility/polarity/chemotaxis; DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 20q13.1. Cellular Component: nucleoplasm; nuclear matrix; cytoplasm; nuclear chromatin; nucleus. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein homodimerization activity; DNA binding; protein heterodimerization activity; chromatin binding; transcription factor activity; transcription factor binding; glucocorticoid receptor binding. Biological Process: transcription from RNA polymerase II promoter; embryonic placenta development; regulation of interleukin-6 biosynthetic process; mammary gland epithelial cell proliferation; response to lipopolysaccharide; neuron differentiation; positive regulation of osteoblast differentiation; regulation of transcription, DNA-dependent; brown fat cell differentiation; acute-phase response; positive regulation of fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; immune response; negative regulation of neuron apoptosis; inflammatory response; negative regulation of transcription, DNA-dependent
size4 :
10x96-Strip-Wells