catalog number :
MBS005918
products type :
ELISA Kit
products full name :
Human Gastric Inhibitory Polypeptide ELISA Kit
products short name :
[Gastric Inhibitory Polypeptide]
other names :
[gastric inhibitory polypeptide preproprotein; Gastric inhibitory polypeptide; gastric inhibitory polypeptide; incretin hormone; glucose-dependent insulinotropic polypeptide; gastric inhibitory polypeptide; Glucose-dependent insulinotropic polypeptide; Incretin hormone]
products gene name :
[GIP]
other gene names :
[GIP; GIP; GIP]
uniprot entry name :
GIP_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 31.2pg/ml-1000pg/ml. Sensitivity: 5.0pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of GIF (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_004114.1
ncbi gb acc num :
NM_004123.2
ncbi mol weight :
17,108 Da
ncbi pathways :
Class B/2 (Secretin Family Receptors) Pathway (106378); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Glucagon-type Ligand Receptors Pathway (106380); Incretin Synthesis, Secretion, And Inactivation Pathway (187170); Insulin Secretion Pathway (777534); Metabolism Of Proteins Pathway (106230); Peptide Hormone Metabolism Pathway (771603); Signal Transduction Pathway (477114)
ncbi summary :
This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]
uniprot summary :
GIP: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. Belongs to the glucagon family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q21.3-q22. Cellular Component: extracellular space; cell soma; endoplasmic reticulum lumen; extracellular region. Molecular Function: hormone activity. Biological Process: response to drug; response to peptide hormone stimulus; adult locomotory behavior; positive regulation of insulin secretion; female pregnancy; signal transduction; response to amino acid stimulus; sensory perception of pain; response to lipid; response to organic cyclic substance; endocrine pancreas development; memory; response to starvation; response to selenium ion; cellular protein metabolic process; response to glucose stimulus; response to axon injury; regulation of insulin secretion
size4 :
10x96-Strip-Wells