Fish Peroxisome Proliferators Activated Receptor gamma ELISA Kit | MyBioSource MBS005886 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Fish Peroxisome Proliferators Activated Receptor gamma ELISA Kit

catalog :

MBS005886

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

citations: 1

Reference
Ekambaram P, Parasuraman P. Differential expression of sirtuin 2 and adipocyte maturation restriction: an adaptation process during hypoxia in fish. Biol Open. 2017;6:1375-1382 pubmed publisher

product information

catalog number :

MBS005886

products type :

ELISA Kit

products full name :

Fish Peroxisome Proliferators Activated Receptor gamma ELISA Kit

products short name :

[Peroxisome Proliferators Activated Receptor gamma]

other names :

[peroxisome proliferator-activated receptor gamma isoform 1; Peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma; PPAR gamma; PPAR-gamma; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated receptor gamma 1; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3]

products gene name :

[PPARgamma]

other gene names :

[PPARG; PPARG; GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; NR1C3; PPAR-gamma]

uniprot entry name :

PPARG_HUMAN

reactivity :

Fish

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Rat Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of PPARD (hereafter termed "analyte") in undiluted original Rat serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

ncbi gi num :

116284373

ncbi acc num :

NP_619725.2

ncbi gb acc num :

NM_138711.3

uniprot acc num :

P37231

ncbi mol weight :

57,620 Da

ncbi pathways :

Adipogenesis Pathway (198832); Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway (137993); Developmental Biology Pathway (477129); Energy Metabolism Pathway (198907); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Metabolism Pathway (477135)

ncbi summary :

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

uniprot summary :

PPAR-gamma: a transcription factor, member of the nuclear hormone receptor superfamily. Receptor for hypolipidemic drugs and fatty acids. Preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage. Regulator of adipogenesis and lipid metabolism, modulates insulin sensitivity, cell proliferation and inflammation. Phosphorylated and inhibited by MAP kinase. Heterodimerizes with the retinoid X receptor. Interacts with NCOA6 coactivator, leading to a strong increase in transcription of target genes. Two splice-variant isoforms have been described. Protein type: Nuclear receptor; DNA-binding. Chromosomal Location of Human Ortholog: 3p25. Cellular Component: nucleoplasm; perinuclear region of cytoplasm; nucleus; cytosol. Molecular Function: ligand-dependent nuclear receptor activity; transcription activator binding; zinc ion binding; drug binding; alpha-actinin binding; protein phosphatase binding; retinoid X receptor binding; arachidonic acid binding; protein binding; enzyme binding; DNA binding; ligand-dependent nuclear receptor transcription coactivator activity; prostaglandin receptor activity; sequence-specific DNA binding; estrogen receptor binding; steroid hormone receptor activity; chromatin binding; transcription factor activity. Biological Process: negative regulation of smooth muscle cell proliferation; negative regulation of collagen biosynthetic process; heart development; positive regulation of transcription, DNA-dependent; low-density lipoprotein receptor biosynthetic process; cell maturation; rhythmic process; lipid homeostasis; negative regulation of transcription from RNA polymerase II promoter; response to lipid; glucose homeostasis; signal transduction; response to vitamin A; response to caffeine; epithelial cell differentiation; regulation of blood pressure; positive regulation of oligodendrocyte differentiation; response to nutrient; placenta development; long-chain fatty acid transport; caspase activation; transcription initiation from RNA polymerase II promoter; organ regeneration; response to retinoic acid; cell fate commitment; monocyte differentiation; negative regulation of acute inflammatory response; regulation of circadian rhythm; response to starvation; negative regulation of telomerase activity; G-protein coupled receptor protein signaling pathway; cellular response to insulin stimulus; lipoprotein transport; response to mechanical stimulus; response to estrogen stimulus; response to low density lipoprotein stimulus; positive regulation of fatty acid oxidation; white fat cell differentiation; brown fat cell differentiation; positive regulation of fat cell differentiation; innate immune response; positive regulation of transcription factor activity; fatty acid oxidation; gene expression; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; response to cold; lipid metabolic process; negative regulation of cell growth; negative regulation of transcription, DNA-dependent; positive regulation of phagocytosis, engulfment. Disease: Obesity; Lipodystrophy, Familial Partial, Type 3; Carotid Intimal Medial Thickness 1; Diabetes Mellitus, Noninsulin-dependent

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage