catalog number :
MBS005851
products type :
ELISA Kit
products full name :
Chicken D Lactic Acid ELISA Kit
products short name :
[D Lactic Acid]
other names :
[delta-like protein A; Delta-like protein A; delta-like protein A; deltaA]
products gene name :
[DLA]
other gene names :
[dla; dla; cb335; fa04c10; wu:fa04c10; DeltaA]
uniprot entry name :
DLLA_DANRE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Chicken body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 1.56 mug/ml - 50 mug/ml. Sensitivity: 0.1 mug/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DLA (hereafter termed "analyte") in undiluted original Chicken body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_571029.1
ncbi gb acc num :
NM_130954.1
ncbi mol weight :
84,969 Da
ncbi pathways :
Activated NOTCH1 Transmits Signal To The Nucleus Pathway (1003441); Constitutive Signaling By NOTCH1 HD Domain Mutants Pathway (1003444); Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway (1003448); Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway (1003446); Constitutive Signaling By NOTCH1 T(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Pathway (1003439); Disease Pathway (1003331); FBXW7 Mutants And NOTCH1 In Cancer Pathway (1003449); NOTCH2 Activation And Transmission Of Signal To The Nucleus Pathway (1003647); Notch Signaling Pathway (83639); Notch Signaling Pathway (473)
uniprot summary :
Function: Acts as a ligand for Notch receptors and is involved in primary neurogenesis. Can activate Notch receptors, thereby playing a key role in lateral inhibition, a process that prevents the immediate neighbors of each nascent neural cell from simultaneously embarking on neural differentiation. Required for boundary formation during segmentation of the hindbrain. Required for midline cell fate specification prior to germ layer formation; regulates specification of floorplate, notochord and hypochord. In inner ear, it prevents adjacent cells from adopting the same cell fate. Plays a role in angiogenesis. Ref.1 Ref.4 Ref.5 Ref.8. Subunit structure: Interacts with mib. Ref.6. Subcellular location: Membrane; Single-pass type I membrane protein . By similarity. Tissue specificity: Expressed in nervous system. In the developing nervous system, it is expressed in overlapping regions with deltaB (dlb) and deltaD (dld); in the neural plate, dla is expressed in patches of contiguous cells with dld, while dlb is confined to scattered cells within those patches that will differentiate as neurons. In 24 hours embryos, expressed in the hindbrain in stripes adjacent to rhombomere boundaries, but not in the actual boundary cells. During gastrulation and tail formation, expressed in embryonic midline cells. Expressed in hair cells of inner ear. Ref.1 Ref.3 Ref.4 Ref.7 Ref.8. Developmental stage: Initiated in the neuroectoderm before that of dld. In the developing trunk neural plate and neural tube, it is initiated in the epiblast prior to completion of gastrulation. At the 2- to 3-somite stage (10.5 hours) low levels are distributed throughout the trunk CNS, with cells expressing higher levels found in the medial and lateral regions of the neural plate. These regions correspond to the positions at which primary motoneurons and Rohon Beard neurons (RBs) originate. Cells expressing high levels do not form contiguous domains. Rather, single cells or small clusters of several cells showing high expression are interspersed with cells having lower expression. Expression is specific to the developing nervous system, and continues to be expressed broadly in the CNS throughout neurogenesis. Expressed in cells specified for neuronal fates. At 24 hours, and throughout later embryogenesis, it is broadly expressed in the spinal cord, suggesting that it is expressed by many types of cells. Expressed as neuronal specification occurs and is subsequently down-regulated in cells that have acquired specific neuronal fates. Ref.1. Post-translational modification: Ubiquitinated by mib, leading to its endocytosis and subsequent degradation. Ref.6. Sequence similarities: Contains 1 DSL domain.Contains 8 EGF-like domains. Sequence caution: The sequence AAC41249.1 differs from that shown. Reason: Frameshift at position 726.
size4 :
10x96-Strip-Wells