catalog number :
MBS005506
products type :
ELISA Kit
products full name :
Rabbit Galectin 9 ELISA Kit
products short name :
Galectin 9
other names :
galectin-9 isoform short; Galectin-9; galectin-9; gal-9; ecalectin; galectin 9; tumor antigen HOM-HD-21; urate transporter/channel protein; lectin, galactoside-binding, soluble, 9; Ecalectin; Tumor antigen HOM-HD-21
products gene name :
GAL9
other gene names :
LGALS9; LGALS9; HUAT; LGALS9A; Gal-9
uniprot entry name :
LEG9_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: The sensitivity of this kit is 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GAL9 (hereafter termed this analyte) in undiluted original Rabbit body fluids, tissue homogenates, secretions and feces samples.
ncbi acc num :
NP_002299.2
ncbi gb acc num :
NM_002308.3
ncbi mol weight :
39,518 Da
ncbi summary :
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
galectin-9: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 17q11.2. Cellular Component: cytoplasm. Molecular Function: signal transducer activity; galactose binding; carbohydrate binding. Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction