catalog number :
MBS005003
products type :
ELISA Kit
products full name :
Human Peptide Yy ELISA Kit
products short name :
Peptide Yy
other names :
peptide YY preproprotein; Peptide YY; peptide YY; prepro-PYY; peptide tyrosine tyrosine; peptide YY; PYY-I; Peptide tyrosine tyrosineCleaved into the following chain:Peptide YY(3-36); Alternative name(s):; PYY-II
other gene names :
PYY; PYY; PYY1; PYY-I; PYY
uniprot entry name :
PYY_HUMAN
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich
ncbi acc num :
NP_004151.3
ncbi gb acc num :
NM_004160.4
ncbi mol weight :
11,145 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Peptide Ligand-binding Receptors Pathway (106358); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
The protein encoded by this gene is proteolytically processed to release a peptide that inhibits pancreatic secretion and mobility in the gut. Rare variations in this gene could increase susceptibility to obesity. [provided by RefSeq, Jul 2010]
uniprot summary :
PYY: This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 17q21.1. Cellular Component: extracellular space; extracellular region. Molecular Function: neuropeptide hormone activity; protein binding; G-protein-coupled receptor binding; hormone activity. Biological Process: cell proliferation; G-protein coupled receptor protein signaling pathway; cell-cell signaling; eating behavior; neuropeptide signaling pathway; digestion; regulation of appetite; feeding behavior; cytoskeleton organization and biogenesis; cell motility. Disease: Obesity