ELISA/assay

Fish Hexokinase 2 ELISA Kit

MBS004980

96 Strip Wells

600 USD

ELISA Kit

Fish Hexokinase 2 ELISA Kit

Hexokinase 2

Hexokinase 2; Hexokinase-2; hexokinase-2; HK II; hexokinase type II; hexokinase-2, muscle; muscle form hexokinase; hexokinase 2; Hexokinase type II; HK II; Muscle form hexokinase

HK2

HK2; HK2; HKII; HXK2; HK II

HXK2_HUMAN

Fish

Store all reagents at 2-8 degree C

ELISA Type: Sandwich

39963174

AAH64369.1

P52789

102,380 Da

Amino Sugar And Nucleotide Sugar Metabolism Pathway 82979!!Amino Sugar And Nucleotide Sugar Metabolism Pathway 350!!Butirosin And Neomycin Biosynthesis Pathway 145809!!Butirosin And Neomycin Biosynthesis Pathway 145786!!Carbohydrate Digestion And Absorption Pathway 170720!!Carbohydrate Digestion And Absorption Pathway 170654!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Fructose And Mannose Metabolism Pathway 82930!!Fructose And Mannose Metabolism Pathway 291

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]

Catalytic activity: ATP + D-hexose = ADP + D-hexose 6-phosphate. Enzyme regulation: Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P. Pathway: Carbohydrate metabolism; hexose metabolism. Subunit structure: Monomer . By similarity. Subcellular location: Mitochondrion outer membrane . By similarity. Note: Its hydrophobic N-terminal sequence may be involved in membrane binding . By similarity. Tissue specificity: Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Domain: The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule. Polymorphism: Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease. Miscellaneous: In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Sequence similarities: Belongs to the hexokinase family.

96 Strip Wells

600 USD