product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit ERK3 (Phospho-Ser189) Antibody
catalog :
MBS004547
quantity :
0.05 mL
price :
270 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS004547
products type :
Antibody
products full name :
Rabbit ERK3 (Phospho-Ser189) Antibody
products short name :
ERK3 (Phospho-Ser189)
products name syn :
EC 2.7.11.24; ERK-3; ERK3; Extracellular signal-regulated kinase 3; MAP kinase isoform p97; MAPK6; MK06; Mitogen-activated protein kinase 6; PRKM4; PRKM6; kinase ERK3; p55-MAPK; p97-MAPK
other names :
mitogen-activated protein kinase 6; Mitogen-activated protein kinase 6; mitogen-activated protein kinase 6; ERK-3; MAPK 6; p97-MAPK; MAP kinase 6; MAP kinase isoform p97; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6; extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; mitogen-activated protein kinase 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97
products gene name :
ERK3
other gene names :
MAPK6; MAPK6; ERK3; PRKM6; p97MAPK; HsT17250; ERK3; PRKM6; MAP kinase 6; MAPK 6; ERK-3; p97-MAPK
uniprot entry name :
MK06_HUMAN
host :
Rabbit
reactivity :
Human, mouse, rat
sequence length :
721
specificity :
ERK3 (Phospho-Ser189) antibody detects endogenous levels of ERK3 only when phosphorylated at serine 189.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation
form :
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
concentration :
1 mg/ml
tested application :
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
app notes :
WB: 1:500~1:1000. IHC: 1:50~1:100. ELISA: 1:5000
other info1 :
Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human ERK3 around the phosphorylation site of serine 189 (H-L-Sp-E-G).
other info2 :
All Sites: Human: Ser186; Mouse: Ser189; Rat: Ser189
ncbi gi num :
4506091
ncbi acc num :
NP_002739.1
ncbi gb acc num :
NM_002748.3
uniprot acc num :
Q16659
ncbi mol weight :
82,681 Da
ncbi pathways :
Focal Adhesion Pathway (198795); Insulin Signaling Pathway (198845); Integrin-mediated Cell Adhesion Pathway (198816); MAPK Signaling Pathway (198779); Regulation Of Actin Cytoskeleton Pathway (198874); Signal Transduction Of S1P Receptor Pathway (198819)
ncbi summary :
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. [provided by RefSeq, Jul 2008]
uniprot summary :
ERK3: a protein kinase of the MAPK family. Plays a critical role in the regulation of cell growth and differentiation. Localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters. Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.24; Protein kinase, CMGC; Kinase, protein; CMGC group; MAPK family; MAPK/ERK subfamily; ERK subfamily. Chromosomal Location of Human Ortholog: 15q21. Cellular Component: cytoplasm; nucleus. Molecular Function: MAP kinase activity; protein serine/threonine kinase activity; protein binding; protein heterodimerization activity; protein kinase binding; ATP binding. Biological Process: MAPKKK cascade; signal transduction; cell cycle; protein amino acid phosphorylation
size1 :
0.05 mL
price1 :
270 USD
size2 :
0.1 mL
price2 :
445
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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