product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit MRPS22 Antibody
catalog :
MBS003771
quantity :
0.05 mL
price :
270 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS003771
products type :
Antibody
products full name :
Rabbit MRPS22 Antibody
products short name :
MRPS22
other names :
28S ribosomal protein S22, mitochondrial; 28S ribosomal protein S22, mitochondrial; 28S ribosomal protein S22, mitochondrial; S22mt; mitochondrial ribosomal protein S22
products gene name :
MRPS22
other gene names :
MRPS22; MRPS22; GIBT; GK002; C3orf5; COXPD5; RPMS22; MRP-S22; C3orf5; RPMS22; MRP-S22; S22mt
uniprot entry name :
RT22_HUMAN
host :
Rabbit
reactivity :
Human
sequence length :
360
specificity :
MRPS22 antibody detects endogenous levels of total MRPS22 protein.
purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
form :
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
concentration :
1 mg/ml
storage stability :
Store at -20 Deg. C/1 year
tested application :
ELISA (EIA), Immunofluorescence (IF), Western Blot (WB)
app notes :
WB: 1:500~ 1:1000. IF: 1:100~ 1:500. ELISA: 1:40000
other info1 :
Immunogen: The antiserum was produnced against synthesized peptide derived from internal of human MRPS22.
ncbi gi num :
9910244
ncbi acc num :
NP_064576.1
ncbi gb acc num :
NM_020191.2
uniprot acc num :
P82650
ncbi mol weight :
41,280 Da
ncbi summary :
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq, Jul 2008]
uniprot summary :
MRPS22: Defects in MRPS22 are the cause of combined oxidative phosphorylation deficiency type 5 (COXPD5). COXPD5 is an antenatal mitochondrial disease. Patients show edema, cardiomyopathy, tubulopathy, and hypotonia. Protein type: Mitochondrial; Translation; Ribosomal. Chromosomal Location of Human Ortholog: 3q23. Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial small ribosomal subunit; mitochondrial ribosome. Molecular Function: structural constituent of ribosome. Biological Process: mitochondrial translation; organelle organization and biogenesis. Disease: Combined Oxidative Phosphorylation Deficiency 5
size1 :
0.05 mL
price1 :
270 USD
size2 :
0.1 mL
price2 :
445
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
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