antibody

Rabbit YB1 (Phospho-Ser102) Antibody

MBS003532

0.1 mL

440 USD

polyclonal

rabbit

nonconjugated

human, mouse, rat

Antibody

Rabbit YB1 (Phospho-Ser102) Antibody

[YB1 (Phospho-Ser102)]

[nuclease-sensitive element-binding protein 1; Nuclease-sensitive element-binding protein 1; nuclease-sensitive element-binding protein 1; CBF-A; EFI-A; DNA-binding protein B; Y-box-binding protein 1; Y-box transcription factor; enhancer factor I subunit A; nuclease sensitive element binding protein 1; CCAAT-binding transcription factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; Y box binding protein 1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1]

[YB1]

[YBX1; YBX1; YB1; BP-8; CSDB; DBPB; YB-1; CSDA2; NSEP1; NSEP-1; MDR-NF1; NSEP1; YB1; CBF-A; DBPB; EFI-A; YB-1]

YBOX1_HUMAN

polyclonal

rabbit

Human,Mouse,Rat

324

Phospho-IRAK4 (Thr345/Ser346) Ab detects endogenous levels of IRAK4 only when phosphorylated at Thr345/Ser346

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

1 mg/ml

Store at -20°C.Stable for 12 months from date of receipt

WB 1:1000-3000. For western blot, incubate membrane with diluted Ab in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4°C with gentle shaking, overnight.

Western Blot (WB)

34098946

NP_004550.2

NM_004559.3

P67809

50 kDa

BDNF Signaling Pathway (712093); Gene Expression Pathway (105937); Processing Of Capped Intron-Containing Pre-mRNA Pathway (160950); SIDS Susceptibility Pathways (198901); Signaling Events Mediated By PTP1B Pathway (138017); MRNA Splicing Pathway (105951); MRNA Splicing - Major Pathway (105952); MRNA Processing Pathway (198843)

YB-1: a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP. Involved in cisplatin resistance. Seems to be a negative regulatory factor. May play a role in both transcriptional and translational regulation of spermatogenesis. Found at very low levels at day 10 and levels increase at day 15 and persist throughout adulthood. Protein type: Transcription factor; RNA-binding; RNA processing; RNA splicing. Chromosomal Location of Human Ortholog: 1p34. Cellular Component: nucleoplasm; nuclear membrane; intracellular membrane-bound organelle; stress granule; cytoplasm; nucleus; ribonucleoprotein complex; U12-dependent spliceosome. Molecular Function: protein binding; DNA binding; RNA binding; double-stranded DNA binding; transcription factor activity; single-stranded DNA binding. Biological Process: transcription from RNA polymerase II promoter; negative regulation of striated muscle cell differentiation; nuclear mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent; in utero embryonic development; positive regulation of cell division; RNA splicing; positive regulation of transcription from RNA polymerase II promoter; gene expression; negative regulation of transcription from RNA polymerase II promoter

0.1 mL

440 USD

0.2 mL

715