catalog number :
MBS002942
products full name :
Rabbit NDUFA4 Antibody
products short name :
NDUFA4
other names :
NADH dehydrogenase; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; complex I-MLRQ; Complex I 9kDa subunit; NADH-ubiquinone oxidoreductase MLRQ subunit; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa; Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit
products gene name :
NDUFA4
other gene names :
NDUFA4; NDUFA4; MLRQ; CI-9k; CI-MLRQ; CI-MLRQ
uniprot entry name :
NDUA4_HUMAN
reactivity :
Human, mouse, rat
specificity :
NDUFA4 Antibody detects endogenous levels of total NDUFA4
purity :
Immunogen affinity purified
form :
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
storage stability :
Store at -20 degree C. Stable for 12 months from date of receipt.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB 1:500-1:2000 . Optimal dilutions/concentrations should be determined by the end user.
products description :
Background/Introduction: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
ncbi acc num :
NP_002480.1
ncbi gb acc num :
NM_002489.3
ncbi mol weight :
9,370 Da
ncbi pathways :
Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Electron Transport Chain Pathway (198860); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Metabolism Pathway (477135); NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway (413408); Oxidative Phosphorylation Pathway (198870); Oxidative Phosphorylation Pathway (82942); Oxidative Phosphorylation Pathway (303)
ncbi summary :
The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]
uniprot summary :
NDUFA4: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA4 subunit family. Protein type: Oxidoreductase; Mitochondrial; Energy Metabolism - oxidative phosphorylation; EC 1.6.5.3; EC 1.6.99.3. Chromosomal Location of Human Ortholog: 7p21.3. Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex IV; mitochondrial respiratory chain complex I. Molecular Function: protein binding; cytochrome-c oxidase activity; NADH dehydrogenase (ubiquinone) activity; protein complex binding. Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone