Rabbit LAMA5 Antibody | MyBioSource MBS002764 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Rabbit LAMA5 Antibody

catalog :

MBS002764

quantity :

0.05 mL

price :

270 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS002764

products type :

Antibody

products full name :

Rabbit LAMA5 Antibody

products short name :

LAMA5

other names :

laminin subunit alpha-5; Laminin subunit alpha-5; laminin subunit alpha-5; laminin alpha-5 chain; laminin-10 subunit alpha; laminin-11 subunit alpha; laminin-15 subunit alpha; laminin, alpha 5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha

products gene name :

LAMA5

other gene names :

LAMA5; LAMA5; KIAA0533; KIAA1907

uniprot entry name :

LAMA5_HUMAN

host :

Rabbit

reactivity :

Human (Identities = 100%, Positives = 100%). Mouse (Identities = 92%, Positives = 100%)

sequence length :

3695

specificity :

LAMA5 antibody detects endogenous levels of total LAMA5 protein.

purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

form :

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

concentration :

1 mg/ml

storage stability :

Store at -20 deg C/ 1 year

tested application :

Immunohistochemistry (IHC), ELISA (EIA)

app notes :

IHC: 1:50~1:100. ELISA: 1:20000

other info1 :

Immunogen: The antiserum was produced against synthesized peptide derived from internal of human LAMA5.

ncbi gi num :

21264602

ncbi acc num :

NP_005551.3

ncbi gb acc num :

NM_005560.3

uniprot acc num :

O15230

ncbi mol weight :

399,737 Da

ncbi pathways :

Alpha6-Beta4 Integrin Signaling Pathway (198807); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); Inflammatory Response Pathway (198766); PI3K-Akt Signaling Pathway (692234)

ncbi summary :

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. [provided by RefSeq, Jul 2008]

uniprot summary :

LAMA5: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Protein type: Secreted, signal peptide; Secreted; Extracellular matrix; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 20q13.2-q13.3. Cellular Component: extracellular matrix; extracellular space; laminin-5 complex; laminin-1 complex; laminin-10 complex; extracellular region; basement membrane; basal lamina; nucleus. Molecular Function: integrin binding; structural molecule activity. Biological Process: integrin-mediated signaling pathway; regulation of cell adhesion; focal adhesion formation; endothelial cell differentiation; extracellular matrix organization and biogenesis; muscle development; cell migration; regulation of embryonic development; cell recognition; cytoskeleton organization and biogenesis; regulation of cell migration; regulation of cell proliferation; odontogenesis of dentine-containing teeth; cell proliferation; extracellular matrix disassembly; embryonic development; morphogenesis of embryonic epithelium; hair follicle development; ureteric bud branching; cilium biogenesis; angiogenesis; cell differentiation; neural crest cell migration; morphogenesis of a polarized epithelium; lung development

size1 :

0.05 mL

price1 :

270 USD

size2 :

0.1 mL

price2 :

445

more info or order :

MyBioSource product webpage