product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit RGS10 Antibody
catalog :
MBS002640
quantity :
0.1 mL
price :
440 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western blot analysis of extracts from rat brain, using RGS10Ab.
image 2 :
At 1/100 staining Rat kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the Ab for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit Ab was used as the secondary.
product information
catalog number :
MBS002640
products type :
Antibody
products full name :
Rabbit RGS10 Antibody
products short name :
[RGS10]
products name syn :
[Regulator of G-protein signaling 10;RGS10]
other names :
[regulator of G-protein signaling 10 isoform a; Regulator of G-protein signaling 10; regulator of G-protein signaling 10; regulator of G-protein signalling 10; regulator of G-protein signaling 10]
products gene name :
[RGS10]
other gene names :
[RGS10; RGS10; RGS10]
uniprot entry name :
RGS10_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
181
specificity :
RGS10 Antibody detects endogenous levels of total RGS10
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
concentration :
1mg/ml
storage stability :
Store at -20 °C. Stable for 12 months from date of receipt.
tested application :
ELISA (EIA), Western Blot (WB), Immunofluroescence (IF), Immunocytochemistry (ICC)
app notes :
WB 1:500~1:1000. IHC: 1:50~1:200. IF/ICC: 1:100-1:500
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: A synthesized peptide. Subcellular Location: Cytosol; Nucleus; Nucleus
other info2 :
Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
ncbi gi num :
52694755
ncbi acc num :
NP_001005339.1
ncbi gb acc num :
NM_001005339.1
uniprot acc num :
O43665
ncbi mol weight :
20 KD
ncbi pathways :
Calcium Regulation In The Cardiac Cell Pathway (198906); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); Myometrial Relaxation And Contraction Pathways (198759); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
RGS10: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)- alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein. Protein type: GAPs, RGS; GAPs. Chromosomal Location of Human Ortholog: 10q25. Cellular Component: cell soma; cytoplasm; dendritic spine; plasma membrane; nerve terminal; nucleus. Molecular Function: GTPase activator activity. Biological Process: positive regulation of GTPase activity
size1 :
0.1 mL
price1 :
440 USD
size2 :
0.2 mL
price2 :
715
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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