product summary
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company name :
MyBioSource
product type :
antibody
product name :
ALPK1 Antibody
catalog :
MBS001969
quantity :
0.1 mL
price :
440 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, enzyme immunoassay
more info or order :
image
image 1 :
Western blot analysis of extracts from HepG2 cells using ALPK1 Ab.
image 2 :
IHC analysis of paraffin-embedded Human liver cancer tissue, using ALPK1 Ab at 1/50 dilution.
image 3 :
Staining COLO205 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary Ab was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary Ab.
product information
catalog number :
MBS001969
products type :
Antibody
products full name :
ALPK1 Antibody
products short name :
[ALPK1]
products name syn :
[ALPK1; EC 2.7.11.-; LAK; Lymphocyte alpha-kinase]
other names :
[alpha-protein kinase 1 isoform 1; Alpha-protein kinase 1; alpha-protein kinase 1; chromosome 4 kinase; lymphocyte alpha-kinase; lymphocyte alpha-protein kinase; alpha-kinase 1; Chromosome 4 kinase; Lymphocyte alpha-protein kinase]
products gene name :
[ALPK1]
other gene names :
[ALPK1; ALPK1; LAK; 8430410J10Rik; KIAA1527; LAK]
uniprot entry name :
ALPK1_HUMAN
clonality :
Polyclonal
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
1244
specificity :
ALPK1 Ab detects endogenous levels of total ALPK1.
purity :
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin
form :
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
concentration :
1mg/ml
storage stability :
Store at -20°C. Stable for 12 months from date of receipt.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:500~1:1000. IHC: 1:50-1:200. IF/ICC: 1:100-1:500
image1 heading :
Western blot
image2 heading :
Immunohistochemistry
image3 heading :
Immunofluorescence
other info1 :
Immunogen: A synthesized peptide.
other info2 :
Tissue Specificity: Highly expressed in liver. Similarity: Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily. Important: For western blot, incubate membrane with diluted primary Ab in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4°C with gentle shaking, overnight.
products references :
ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder. Lloyd B. Williams MD, PhD, Asif Javed PhD, Margaret M. DeAngelis PhD. Genetics in Medicine (2019)
ncbi gi num :
156151443
ncbi acc num :
NP_001095876.1
ncbi gb acc num :
NM_001102406.1
uniprot acc num :
Q96QP1
ncbi mol weight :
139 KD
ncbi summary :
This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
uniprot summary :
AlphaK3: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation. Belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily. Protein type: Kinase, protein; EC 2.7.11.-; Protein kinase, atypical; ATYPICAL group; Alpha family. Chromosomal Location of Human Ortholog: 4q25. Molecular Function: protein serine/threonine kinase activity; ATP binding. Biological Process: protein amino acid phosphorylation
size1 :
0.1 mL
price1 :
440 USD
size2 :
0.2 mL
price2 :
715
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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