product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Rabbit SNAI1 (Ab-246) Antibody
catalog :
MBS000031
quantity :
0.05 mL
price :
270 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS000031
products type :
Antibody
products full name :
Rabbit SNAI1 (Ab-246) Antibody
products short name :
SNAI1 (Ab-246)
other names :
zinc finger protein SNAI1; Zinc finger protein SNAI1; zinc finger protein SNAI1; protein sna; snail 1 homolog; snail homolog 1; protein snail homolog 1; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family zinc finger 1; Protein snail homolog 1
products gene name :
SNAI1
other gene names :
SNAI1; SNAI1; SNA; SNAH; SNAIL; SLUGH2; SNAIL1; dJ710H13.1; SNAH; Protein sna
uniprot entry name :
SNAI1_HUMAN
host :
Rabbit
reactivity :
Human, mouse
sequence length :
264
form :
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
concentration :
1 mg/ml
tested application :
ELISA (EIA), Western Blot (WB)
ncbi gi num :
18765741
ncbi acc num :
NP_005976.2
ncbi gb acc num :
NM_005985.3
uniprot acc num :
O95863
ncbi mol weight :
29,083 Da
ncbi pathways :
Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Neural Crest Differentiation Pathway (672460); Signaling Events Mediated By Hepatocyte Growth Factor Receptor (c-Met) Pathway (137930); Validated Targets Of C-MYC Transcriptional Activation Pathway (169351)
ncbi summary :
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]
uniprot summary :
Snail1: a protein of the C2H2-type zinc-finger family that regulates transcription. Involved in embryonic mesoderm formation. Plays a role in the epithelial to mesenchymal transition (EMT). EMT is characterized by decreased levels of the epithelial markers E-cadherin and alpha- and beta-catenin, and increased cellular migration and expression of the mesenchymal markers fibronectin, vimentin, N-cadherin and smooth muscle alpha-actin.E Snail binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. NF-kappaB binds and regulates the snail promoter and is critical for EMT, and inhibition of NF-kappaB activity lowered snail levels and morphologically reversed the EMT. Protein type: Transcription factor; C2H2-type zinc finger protein. Chromosomal Location of Human Ortholog: 20q13.2. Cellular Component: cytoplasm; nucleus. Molecular Function: protein binding; metal ion binding; kinase binding. Biological Process: osteoblast differentiation; negative regulation of DNA damage response, signal transduction by p53 class mediator; cell migration; hair follicle morphogenesis; mesoderm formation; positive regulation of transcription, DNA-dependent; epithelial to mesenchymal transition; negative regulation of transcription from RNA polymerase II promoter; palate development; positive regulation of cell migration
size1 :
0.05 mL
price1 :
270 USD
size2 :
0.1 mL
price2 :
445
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!