This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Miltenyi Biotec
product type :
antibody
product name :
CD141 (BDCA-3) Antibody, anti-human, PE
catalog :
130-113-318
quantity :
100 tests in 200 µL
price :
310 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
AD5-14H12
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry
citations: 14
Reference
Jardine L, Barge D, Ames Draycott A, Pagan S, Cookson S, Spickett G, et al. Rapid detection of dendritic cell and monocyte disorders using CD4 as a lineage marker of the human peripheral blood antigen-presenting cell compartment. Front Immunol. 2013;4:495 pubmed publisher
Vanders R, Gibson P, Murphy V, Wark P. Plasmacytoid dendritic cells and CD8 T cells from pregnant women show altered phenotype and function following H1N1/09 infection. J Infect Dis. 2013;208:1062-70 pubmed publisher
Hémont C, Neel A, Heslan M, Braudeau C, Josien R. Human blood mDC subsets exhibit distinct TLR repertoire and responsiveness. J Leukoc Biol. 2013;93:599-609 pubmed publisher
Oosterhoff D, Lougheed S, van de Ven R, Lindenberg J, van Cruijsen H, Hiddingh L, et al. Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition. Oncoimmunology. 2012;1:649-658 pubmed
Dutertre C, Amraoui S, Derosa A, Jourdain J, Vimeux L, Goguet M, et al. Pivotal role of M-DC8? monocytes from viremic HIV-infected patients in TNF? overproduction in response to microbial products. Blood. 2012;120:2259-68 pubmed publisher
Chu C, Ali N, Karagiannis P, Di Meglio P, Skowera A, Napolitano L, et al. Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation. J Exp Med. 2012;209:935-45 pubmed publisher
Ghosh M, McAuliffe B, Subramani J, Basu S, Shapiro L. CD13 regulates dendritic cell cross-presentation and T cell responses by inhibiting receptor-mediated antigen uptake. J Immunol. 2012;188:5489-99 pubmed publisher
van de Ven R, van den Hout M, Lindenberg J, Sluijter B, van Leeuwen P, Lougheed S, et al. Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation. Blood. 2011;118:2502-10 pubmed publisher
Mittag D, Proietto A, Loudovaris T, Mannering S, Vremec D, Shortman K, et al. Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol. 2011;186:6207-17 pubmed publisher
Bosco M, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, et al. Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo. Blood. 2011;117:2625-39 pubmed publisher
Jongbloed S, Kassianos A, McDonald K, Clark G, Ju X, Angel C, et al. Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J Exp Med. 2010;207:1247-60 pubmed publisher
MacDonald K, Munster D, Clark G, Dzionek A, Schmitz J, Hart D. Characterization of human blood dendritic cell subsets. Blood. 2002;100:4512-20 pubmed
Chehimi J, Campbell D, Azzoni L, Bacheller D, Papasavvas E, Jerandi G, et al. Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals. J Immunol. 2002;168:4796-801 pubmed
Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, et al. BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol. 2000;165:6037-46 pubmed
product information
MB Cataloge Number :
130-113-318
Catalog Number :
130-113-318
Product Name :
CD141 (BDCA-3) Antibody, anti-human, PE
Product Type :
Primary antibodies
Host Species :
mouse IgG1κ
Clonality :
monoclonal
Conjugation :
PE
Antigen Modification :
CD141 (BDCA-3)
Clone Name :
AD5-14H12
Isotype :
Isotype Control Antibody, mouse IgG1
Size :
100 tests in 200 µL
US List Price :
310 USD
Product Description :
Detection of human CD141 (BDCA-3)+ type-2 myeloid dendritic cells (MDC2s)
ALTnames :
THBD, AHUS6, BDCA3, THPH12, THRM, TM
Specificity :
human
Concentration :
1:50
Uses :
For research use only
Application Summary :
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
Storage :
Store protected from light at 2–8 °C. Do not freeze.
company information
Miltenyi Biotec
Friedrich-Ebert-Strae 68
51429 Bergisch Gladbach
macs@miltenyibiotec.com
https://www.miltenyibiotec.com
1 800 FOR MACS
headquarters: Germany