This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Miltenyi Biotec
product type :
antibody
product name :
LGR5 Antibody, anti-human, PE-Vio® 770, REAfinity™
catalog :
130-112-439
quantity :
100 tests in 200 µL
price :
365 USD
clonality :
monoclonal
host :
human
conjugate :
PE
clone name :
REA762
reactivity :
human
application :
flow cytometry
citations: 9
Reference
Dame M, Jiang Y, Appelman H, Copley K, McClintock S, Aslam M, et al. Human colonic crypts in culture: segregation of immunochemical markers in normal versus adenoma-derived. Lab Invest. 2014;94:222-34 pubmed publisher
Barker N, Rookmaaker M, Kujala P, Ng A, Leushacke M, Snippert H, et al. Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development. Cell Rep. 2012;2:540-52 pubmed publisher
Kemper K, Prasetyanti P, de Lau W, Rodermond H, Clevers H, Medema J. Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells. Stem Cells. 2012;30:2378-86 pubmed publisher
de Lau W, Barker N, Low T, Koo B, Li V, Teunissen H, et al. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature. 2011;476:293-7 pubmed publisher
Carmon K, Gong X, Lin Q, Thomas A, Liu Q. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2011;108:11452-7 pubmed publisher
Barker N, Huch M, Kujala P, van de Wetering M, Snippert H, van Es J, et al. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell. 2010;6:25-36 pubmed publisher
Barker N, Ridgway R, van Es J, van de Wetering M, Begthel H, van den Born M, et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature. 2009;457:608-11 pubmed publisher
Jaks V, Barker N, Kasper M, van Es J, Snippert H, Clevers H, et al. Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat Genet. 2008;40:1291-9 pubmed publisher
Barker N, van Es J, Kuipers J, Kujala P, van den Born M, Cozijnsen M, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 2007;449:1003-7 pubmed
product information
MB Cataloge Number :
130-112-439
Catalog Number :
130-112-439
Product Name :
LGR5 Antibody, anti-human, PE-Vio® 770, REAfinity™
Product Type :
Primary antibodies, Recombinant antibodies
Host Species :
recombinant human IgG1
Clonality :
monoclonal
Conjugation :
PE-Vio 770
Antigen Modification :
LGR5
Clone Name :
REA762
Isotype :
REA Control Antibody (S), human IgG1
Size :
100 tests in 200 µL
US List Price :
365 USD
Product Description :
Identification and enumeration of LGR5+ cells by flow cytometry
ALTnames :
Fex, GPR49, GPR67, GRP49, HG38
Specificity :
human
Concentration :
1:50
Uses :
For research use only
Application Summary :
Flow cytometry
Storage :
Store protected from light at 2–8 °C. Do not freeze.
company information
Miltenyi Biotec
Friedrich-Ebert-Strae 68
51429 Bergisch Gladbach
macs@miltenyibiotec.com
https://www.miltenyibiotec.com
1 800 FOR MACS
headquarters: Germany