NF-κB p65 pS529 Antibody, anti-human, FITC, REAfinity™ | Miltenyi Biotec 130-107-781 product information

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product summary

company name :

Miltenyi Biotec

product type :

antibody

product name :

NF-κB p65 pS529 Antibody, anti-human, FITC, REAfinity™

catalog :

130-107-781

quantity :

100 tests in 1 mL

price :

238,00 USD

clonality :

monoclonal

host :

human

conjugate :

FITC

clone name :

REA348

reactivity :

human

application :

flow cytometry

citations: 2

Reference
Oeckinghaus A, Hayden M, Ghosh S. Crosstalk in NF-?B signaling pathways. Nat Immunol. 2011;12:695-708 pubmed publisher
Viatour P, Merville M, Bours V, Chariot A. Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation. Trends Biochem Sci. 2005;30:43-52 pubmed

product information

Catalog Number :

130-107-781

Product Name :

NF-κB p65 pS529 Antibody, anti-human, FITC, REAfinity™

Product Type :

Antibodies

Host Species :

cell line

Clonality :

monoclonal

Conjugation :

FITC

Antigen Modification :

NF-κB p65 pS529

Clone Name :

REA348

Isotype :

recombinant human IgG1

Light Chain :

kappa light chain

Size :

100 tests in 1 mL

US List Price :

238,00 USD

Product Description :

Clone REA348 recognizes the human NF-κB p65 antigen phosphorylated at serine 529 (pS529). NF-κB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis, and apoptosis. It is a homo- or heterodimeric complex and the heterodimeric p65-p50 complex is the most abundant one. Optimal induction of NF-κB target genes also requires phosphorylation of NF-κB proteins, such as p65, within their transactivation domain by a variety of kinases in response to distinct stimuli. Additional information: Clone REA348 displays negligible binding to Fc receptors.

ALTnames :

NFKB1, EBP-1, KBF1, NF-kB1, NFKB-p105, NFKB-p50, p105, p50, NF-kB

Specificity :

human

Concentration :

1:11

Uses :

For research use only

Application Summary :

Intracellular flow cytometry

Storage :

Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.