Anti-GFAP antibodies | Miltenyi Biotec 130-105-329 product information

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product summary

company name :

Miltenyi Biotec

product type :

antibody

product name :

Anti-GFAP antibodies

catalog :

130-105-329

quantity :

for 30 tests

clonality :

recombinant

host :

human

conjugate :

clone name :

REA335

reactivity :

human, mouse, rat

application :

flow cytometry

product information

Item Name :

Anti-GFAP antibodies

Catalog Number :

130-105-329

Quantity :

for 30 tests

Target :

GFAP

Reactivity :

human, mouse, rat

Applications :

Flow Cytometry

Primary / Secondary :

Primary

Host :

human

Conjugate/Tag/Label :

Format :

Antibodies are supplied in buffer containing stabilizer and 0.05% sodium azide.

Isotype :

recombinant human IgG1

Clone :

REA335

Clonality :

recombinant

Long text :

Clone REA335 recognizes the human, mouse and rat glial fibrillary acidic protein (GFAP), the main intermediate filament protein in mature astrocytes and an important component of the cytoskeleton in astrocytes during development. GFAP is expressed exclusively in astrocytes in the central nervous system. It has been shown to be involved in astrocyte functions, which are important during regeneration, synaptic plasticity, and reactive gliosis. Moreover, different subpopulations of astrocytes have been identified, which are likely to have distinctive tasks in brain physiology and pathology, and which are not only classified by their spatial and temporal appearance, but also by their specific expression of intermediate filaments, including distinct GFAP isoforms. Additional information: Clone REA335 displays negligible binding to Fc receptors.