CD106 (VCAM-1) Antibody, anti-human, FITC, REAfinity™ | Miltenyi Biotec 130-104-162 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Miltenyi Biotec

product type :

antibody

product name :

CD106 (VCAM-1) Antibody, anti-human, FITC, REAfinity™

catalog :

130-104-162

quantity :

30 tests in 300 µL

price :

84,00 USD

clonality :

monoclonal

host :

human

conjugate :

FITC

clone name :

REA269

reactivity :

human

application :

flow cytometry

citations: 2

Reference
Johnson L, Jackson D. Cell traffic and the lymphatic endothelium. Ann N Y Acad Sci. 2008;1131:119-33 pubmed publisher
Barreiro O, Yanez Mo M, Serrador J, Montoya M, Vicente Manzanares M, Tejedor R, et al. Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. J Cell Biol. 2002;157:1233-45 pubmed

product information

Catalog Number :

130-104-162

Product Name :

CD106 (VCAM-1) Antibody, anti-human, FITC, REAfinity™

Product Type :

Antibodies

Host Species :

cell line

Clonality :

monoclonal

Conjugation :

FITC

Antigen Modification :

CD106 (VCAM-1)

Clone Name :

REA269

Isotype :

recombinant human IgG1

Light Chain :

kappa light chain

Size :

30 tests in 300 µL

US List Price :

84,00 USD

Product Description :

Clone REA269 recognizes the CD106 antigen, a 110 kDa single chain type I glycoprotein, also known as vascular cell adhesion protein 1 (VCAM-1) or INCAM-100. CD106 is expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Upregulation of CD106 in endothelial cells by inflammatory stimuli and cytokines occurs as a result of increased gene transcription. Primarily, CD106 is an endothelial ligand for very late antigen-4 (VLA-4) or integrin α-4/β-7 and mediates both adhesion and signal transduction. The interactions play a pathophysiologic role in leukocyte adhesion, transmigration, and co-stimulation of T cell proliferation. Additional information: Clone REA269 displays negligible binding to Fc receptors.

ALTnames :

VCAM1, INCAM-100

Specificity :

human

Concentration :

1:11

Uses :

For research use only

Application Summary :

Flow cytometry

Storage :

Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.