Dectin-2 Antibody, anti-mouse, FITC | Miltenyi Biotec 130-102-212 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Miltenyi Biotec

product type :

antibody

product name :

Dectin-2 Antibody, anti-mouse, FITC

catalog :

130-102-212

quantity :

30 µg in 1 mL

price :

48,00 USD

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

KVa7-6E7

reactivity :

mouse

application :

flow cytometry

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 1d	Leonardi I, Li X, Semon A, Li D, Doron I, Putzel G, et al. CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi. Science. 2018;359:232-236 pubmed publisher
	Carter R, Thompson C, Reid D, Wong S, Tough D. Induction of CD8+ T cell responses through targeting of antigen to Dectin-2. Cell Immunol. 2006;239:87-91 pubmed
	Taylor P, Reid D, Heinsbroek S, Brown G, Gordon S, Wong S. Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited in vivo. Eur J Immunol. 2005;35:2163-74 pubmed
	Ariizumi K, Shen G, Shikano S, Ritter R, Zukas P, Edelbaum D, et al. Cloning of a second dendritic cell-associated C-type lectin (dectin-2) and its alternatively spliced isoforms. J Biol Chem. 2000;275:11957-63 pubmed
	Fernandes M, Finnegan A, Siracusa L, Brenner C, Iscove N, Calabretta B. Characterization of a novel receptor that maps near the natural killer gene complex: demonstration of carbohydrate binding and expression in hematopoietic cells. Cancer Res. 1999;59:2709-17 pubmed

product information

Catalog Number :

130-102-212

Product Name :

Dectin-2 Antibody, anti-mouse, FITC

Product Type :

Antibodies

Host Species :

rat

Clonality :

monoclonal

Conjugation :

FITC

Antigen Modification :

Dectin-2

Clone Name :

KVa7-6E7

Isotype :

rat IgG2a

Light Chain :

kappa light chain

Size :

30 µg in 1 mL

US List Price :

48,00 USD

Product Description :

Clone KVa7-6E7 specifically recognizes mouse dendritic cell–associated C-type lectin 2 (Dectin-2). Dectin-2 is a type II membrane protein and contains a single carbohydrate recognition domain. Like other C-type lectins, mouse Dectin-2 has conserved motifs for the Ca2+-dependent recognition of mannose. Dectin-2 is located in the natural killer gene complex of chromosome 6. Genomic analyses show that beside a full length Dectin-2 transcript two truncated isoforms are produced by alternative splicing, encoding transmembrane proteins of 168–209 amino acids.¹,² The expression of Dectin-2 on mouse monocytes and macrophages can be induced by zymosan and thioglycollate. 3) Dectin-2 plays a physiological role in antigen presentation and antigen targeting via Dectin-2 can induce a CD8+ T cell response. 4)

ALTnames :

CLEC4N, Clec6a, Clecsf10, Nkcl

Specificity :

mouse

Concentration :

1:10

Uses :

For research use only

Application Summary :

Intracellular flow cytometry, Flow cytometry

Storage :

Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.