product summary
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company name :
Miltenyi Biotec
product type :
antibody
product name :
LGR5 Antibody, anti-human, APC-Vio® 770
catalog :
130-100-856
quantity :
30 tests in 300 µL
price :
158 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
DA03-22H2.8
reactivity :
human
application :
flow cytometry
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 3d
Liang X, Yuan X, Yu J, Wu Y, Li K, Sun C, et al. Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of β-Catenin Target Genes. EBioMedicine. 2017;21:104-116 pubmed publisher
Dame M, Jiang Y, Appelman H, Copley K, McClintock S, Aslam M, et al. Human colonic crypts in culture: segregation of immunochemical markers in normal versus adenoma-derived. Lab Invest. 2014;94:222-34 pubmed publisher
Barker N, Rookmaaker M, Kujala P, Ng A, Leushacke M, Snippert H, et al. Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development. Cell Rep. 2012;2:540-52 pubmed publisher
Kemper K, Prasetyanti P, de Lau W, Rodermond H, Clevers H, Medema J. Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells. Stem Cells. 2012;30:2378-86 pubmed publisher
de Lau W, Barker N, Low T, Koo B, Li V, Teunissen H, et al. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature. 2011;476:293-7 pubmed publisher
Carmon K, Gong X, Lin Q, Thomas A, Liu Q. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2011;108:11452-7 pubmed publisher
Barker N, Huch M, Kujala P, van de Wetering M, Snippert H, van Es J, et al. Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro. Cell Stem Cell. 2010;6:25-36 pubmed publisher
Barker N, Ridgway R, van Es J, van de Wetering M, Begthel H, van den Born M, et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature. 2009;457:608-11 pubmed publisher
Jaks V, Barker N, Kasper M, van Es J, Snippert H, Clevers H, et al. Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat Genet. 2008;40:1291-9 pubmed publisher
Barker N, van Es J, Kuipers J, Kujala P, van den Born M, Cozijnsen M, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 2007;449:1003-7 pubmed
product information
MB Cataloge Number :
130-100-856
Catalog Number :
130-100-856
Product Name :
LGR5 Antibody, anti-human, APC-Vio® 770
Product Type :
Primary antibodies
Host Species :
rat IgG2b
Clonality :
monoclonal
Conjugation :
APC-Vio 770
Antigen Modification :
LGR5
Clone Name :
DA03-22H2.8
Isotype :
Isotype Control Antibody, rat IgG2b
Size :
30 tests in 300 µL
US List Price :
158 USD
Product Description :
Identification and enumeration of LGR5+ cells by flow cytometry
ALTnames :
Fex, GPR49, GPR67, GRP49, HG38
Specificity :
human
Concentration :
1:11
Uses :
For research use only
Application Summary :
Flow cytometry
Storage :
Store protected from light at 2–8 °C. Do not freeze.
more info or order :
company information
Miltenyi Biotec
Friedrich-Ebert-Strae 68
51429 Bergisch Gladbach
macs@miltenyibiotec.com
https://www.miltenyibiotec.com
1 800 FOR MACS
headquarters: Germany