CD79b Antibody, anti-human, APC, REAfinity™ | Miltenyi Biotec 130-099-103 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Miltenyi Biotec

product type :

antibody

product name :

CD79b Antibody, anti-human, APC, REAfinity™

catalog :

130-099-103

quantity :

30 tests in 300 µL

price :

128,00 USD

clonality :

monoclonal

host :

human

conjugate :

APC

clone name :

REA120

reactivity :

human

application :

flow cytometry

citations: 1

Reference
Gordon M, Kato R, Lansigan F, Thompson A, Wall R, Rawlings D. Aberrant B cell receptor signaling from B29 (Igbeta, CD79b) gene mutations of chronic lymphocytic leukemia B cells. Proc Natl Acad Sci U S A. 2000;97:5504-9 pubmed

product information

Catalog Number :

130-099-103

Product Name :

CD79b Antibody, anti-human, APC, REAfinity™

Product Type :

Antibodies

Host Species :

cell line

Clonality :

monoclonal

Conjugation :

APC

Antigen Modification :

CD79b

Clone Name :

REA120

Isotype :

recombinant human IgG1

Light Chain :

kappa light chain

Size :

30 tests in 300 µL

US List Price :

128,00 USD

Product Description :

Clone REA120 detects the extracellular epitope of CD79b, the β chain of heterodimeric molecule CD79. CD79 is composed of an α chain (CD79a) and a β chain (CD79b) and is associated with surface immunoglobulins (Igs) to form the B cell receptor (BCR). CD79b is 37–39 kDa type I integral membrane protein and like CD79a contains an intracellular immunoreceptor tyrosine-based activation motif (ITAM). CD79a/CD79b heterodimer facilitates differentiation of pre–B cells from pro–B cells, surface expression of sIg, signal transduction following antigen recognition, and enodocytosis of recognised antigens. Patients with chronic lymphocytic leukemia (CLL) B cells lack a functional BCR which is often associated with mutations in CD79b coding region. Additional information: Clone REA120 displays negligible binding to Fc receptors.

CrossReactivity :

chimpanzee (Pan troglodytes)

ALTnames :

AGM6, B29, Igb

Specificity :

human, non-human primate

Concentration :

1:11

Uses :

For research use only

Application Summary :

Flow cytometry

Storage :

Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.