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company name :
Miltenyi Biotec
product type :
antibody
product name :
CD133/1 Antibody, anti-human, pure
catalog :
130-092-395
quantity :
100 µg in 1 mL
price :
387 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
W6B3C1
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 30
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human; 1:50; loading ...; fig 4b
Hira V, Wormer J, Kakar H, Breznik B, van der Swaan B, Hulsbos R, et al. Periarteriolar Glioblastoma Stem Cell Niches Express Bone Marrow Hematopoietic Stem Cell Niche Proteins. J Histochem Cytochem. 2018;66:155-173 pubmed publisher
  • western blot; human; loading ...; fig 2a
Zhang C, Mukherjee S, Tucker Burden C, Ross J, Chau M, Kong J, et al. TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3. Mol Oncol. 2017;11:280-294 pubmed publisher
  • flow cytometry; human; fig s1b
  • western blot; human; fig s1d
Torres A, Vargas Y, Uribe D, Jaramillo C, Gleisner A, Salazar Onfray F, et al. Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells. Oncotarget. 2016;7:67373-67386 pubmed publisher
  • western blot; human; 1:150; loading ...; fig 12b
Simile M, Latte G, Demartis M, Brozzetti S, Calvisi D, Porcu A, et al. Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease. Oncotarget. 2016;7:49194-49216 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1
Munthe S, Petterson S, Dahlrot R, Poulsen F, Hansen S, Kristensen B. Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype. PLoS ONE. 2016;11:e0155106 pubmed publisher
  • western blot; human; fig s1
Yamaguchi S, Maida Y, Yasukawa M, Kato T, Yoshida M, Masutomi K. Eribulin mesylate targets human telomerase reverse transcriptase in ovarian cancer cells. PLoS ONE. 2014;9:e112438 pubmed publisher
  • western blot; human; fig 5
Sahlberg S, Spiegelberg D, Glimelius B, Stenerlow B, Nestor M. Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells. PLoS ONE. 2014;9:e94621 pubmed publisher
  • immunohistochemistry; human
Wang Z, Wang B, Shi Y, Xu C, Xiao H, Ma L, et al. Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2. Oncogene. 2015;34:1407-19 pubmed publisher
  • western blot; human
Huang A, Zhou H, Zhao H, Quan Y, Feng B, Zheng M. TMPRSS4 correlates with colorectal cancer pathological stage and regulates cell proliferation and self-renewal ability. Cancer Biol Ther. 2014;15:297-304 pubmed publisher
Yang C, Li B, Yu J, Yang F, Cai K, Chen Z. Ultrasound microbubbles mediated miR-let-7b delivery into CD133+ ovarian cancer stem cells. Biosci Rep. 2018;38: pubmed publisher
Glumac P, LeBeau A. The role of CD133 in cancer: a concise review. Clin Transl Med. 2018;7:18 pubmed publisher
Suwala A, Koch K, Rios D, Aretz P, Uhlmann C, Ogorek I, et al. Inhibition of Wnt/beta-catenin signaling downregulates expression of aldehyde dehydrogenase isoform 3A1 (ALDH3A1) to reduce resistance against temozolomide in glioblastoma in vitro. Oncotarget. 2018;9:22703-22716 pubmed publisher
Alamir H, Alomari M, Salwati A, Saka M, Bangash M, Baeesa S, et al. In situ characterization of stem cells-like biomarkers in meningiomas. Cancer Cell Int. 2018;18:77 pubmed publisher
Yang F, Xing Y, Li Y, Chen X, Jiang J, Ai Z, et al. Monoubiquitination of Cancer Stem Cell Marker CD133 at Lysine 848 Regulates Its Secretion and Promotes Cell Migration. Mol Cell Biol. 2018;38: pubmed publisher
Aaberg Jessen C, Sørensen M, Matos A, Moreira J, Brunner N, Knudsen A, et al. Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas. BMC Cancer. 2018;18:270 pubmed publisher
Brugnoli F, Grassilli S, Lanuti P, Marchisio M, Al Qassab Y, Vezzali F, et al. Up-modulation of PLC-β2 reduces the number and malignancy of triple-negative breast tumor cells with a CD133+/EpCAM+ phenotype: a promising target for preventing progression of TNBC. BMC Cancer. 2017;17:617 pubmed publisher
Khan I, Baeesa S, Bangash M, Schulten H, Alghamdi F, Qashqari H, et al. Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines. Cancer Cell Int. 2017;17:72 pubmed publisher
Jensen S, Petterson S, Halle B, Aaberg Jessen C, Kristensen B. Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo. BMC Cancer. 2017;17:178 pubmed publisher
Sansone P, Berishaj M, Rajasekhar V, Ceccarelli C, Chang Q, Strillacci A, et al. Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles. Cancer Res. 2017;77:1927-1941 pubmed publisher
Hsu M, Yang M, Schnegg C, Hwang S, Ryu B, Alani R. Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis. Lab Invest. 2017;97:725-736 pubmed publisher
Torrente Y, Belicchi M, Marchesi C, D Antona G, Cogiamanian F, Pisati F, et al. Autologous transplantation of muscle-derived CD133+ stem cells in Duchenne muscle patients. Cell Transplant. 2007;16:563-77 pubmed
Bussolati B, Bruno S, Grange C, Buttiglieri S, Deregibus M, Cantino D, et al. Isolation of renal progenitor cells from adult human kidney. Am J Pathol. 2005;166:545-55 pubmed
Laurson J, Selden C, Hodgson H. Hepatocyte progenitors in man and in rodents--multiple pathways, multiple candidates. Int J Exp Pathol. 2005;86:1-18 pubmed
Yu S, Zhang J, Zhao C, Zhang H, Xu Q. Isolation and characterization of the CD133+ precursors from the ventricular zone of human fetal brain by magnetic affinity cell sorting. Biotechnol Lett. 2004;26:1131-6 pubmed
Belicchi M, Pisati F, Lopa R, Porretti L, Fortunato F, Sironi M, et al. Human skin-derived stem cells migrate throughout forebrain and differentiate into astrocytes after injection into adult mouse brain. J Neurosci Res. 2004;77:475-86 pubmed
Richardson G, Robson C, Lang S, Neal D, Maitland N, Collins A. CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci. 2004;117:3539-45 pubmed
Peggs K, Verfuerth S, Pizzey A, Khan N, Guiver M, Moss P, et al. Adoptive cellular therapy for early cytomegalovirus infection after allogeneic stem-cell transplantation with virus-specific T-cell lines. Lancet. 2003;362:1375-7 pubmed
Kaufman D, Hanson E, Lewis R, Auerbach R, Thomson J. Hematopoietic colony-forming cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A. 2001;98:10716-21 pubmed
Uchida N, Buck D, He D, Reitsma M, Masek M, Phan T, et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A. 2000;97:14720-5 pubmed
Corbeil D, Roper K, Hellwig A, Tavian M, Miraglia S, Watt S, et al. The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions. J Biol Chem. 2000;275:5512-20 pubmed
product information
Catalog Number :
130-092-395
Product Name :
CD133/1 Antibody, anti-human, pure
Product Type :
Primary antibodies
Host Species :
mouse IgG1κ
Clonality :
monoclonal
Conjugation :
pure
Antigen Modification :
CD133/1
Clone Name :
W6B3C1
Isotype :
Isotype Control Antibody, mouse IgG1
Size :
100 µg in 1 mL
US List Price :
387 USD
Product Description :
Evaluation of CD133 expression in human tissue by Western blot analysis
ALTnames :
PROM1, AC133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4
Specificity :
human
Uses :
For research use only
Application Summary :
Western blotting
Storage :
Store protected from light at 2–8 °C. Do not freeze.
more info or order :
company information
Miltenyi Biotec
Friedrich-Ebert-Strae 68
51429 Bergisch Gladbach
macs@miltenyibiotec.com
https://www.miltenyibiotec.com
1 800 FOR MACS
headquarters: Germany