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company name :
Miltenyi Biotec
product type :
antibody
product name :
CD133/2 Antibody, anti-human, pure
catalog :
130-090-851
quantity :
50 µg in 1 mL
price :
253 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
293C3
reactivity :
human
application :
immunohistochemistry, flow cytometry, mass cytometry
more info or order :
citations: 33
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; 1:500; loading ...; fig s2d
Wang R, Sharma R, Shen X, Laughney A, Funato K, Clark P, et al. Adult Human Glioblastomas Harbor Radial Glia-like Cells. Stem Cell Reports. 2020;14:338-350 pubmed publisher
  • flow cytometry; human; fig 1f
Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed publisher
  • immunohistochemistry; human; loading ...; fig 6c
Gibier J, Hemon B, Fanchon M, Gaudelot K, Pottier N, Ringot B, et al. Dual role of MUC1 mucin in kidney ischemia-reperfusion injury: Nephroprotector in early phase, but pro-fibrotic in late phase. Biochim Biophys Acta Mol Basis Dis. 2017;1863:1336-1349 pubmed publisher
  • mass cytometry; human; fig s8
Lu X, Horner J, Paul E, Shang X, Troncoso P, Deng P, et al. Effective combinatorial immunotherapy for castration-resistant prostate cancer. Nature. 2017;543:728-732 pubmed publisher
Thier M, Hommerding O, Panten J, Pinna R, García González D, Berger T, et al. Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells. Cell Stem Cell. 2019;24:166-182.e13 pubmed publisher
Al Qassab Y, Grassilli S, Brugnoli F, Vezzali F, Capitani S, Bertagnolo V. Protective role of all-trans retinoic acid (ATRA) against hypoxia-induced malignant potential of non-invasive breast tumor derived cells. BMC Cancer. 2018;18:1194 pubmed publisher
Petrillo C, Thorne L, Unali G, Schiroli G, Giordano A, Piras F, et al. Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells. Cell Stem Cell. 2018;23:820-832.e9 pubmed publisher
Bellio C, DiGloria C, Foster R, James K, Konstantinopoulos P, Growdon W, et al. PARP Inhibition Induces Enrichment of DNA Repair-Proficient CD133 and CD117 Positive Ovarian Cancer Stem Cells. Mol Cancer Res. 2019;17:431-445 pubmed publisher
Glumac P, LeBeau A. The role of CD133 in cancer: a concise review. Clin Transl Med. 2018;7:18 pubmed publisher
Piulats J, Kondo J, Endo H, Ono H, Hagihara T, Okuyama H, et al. Promotion of malignant phenotype after disruption of the three-dimensional structure of cultured spheroids from colorectal cancer. Oncotarget. 2018;9:15968-15983 pubmed publisher
Hayashi T, Yamashita T, Okada H, Nio K, Hara Y, Nomura Y, et al. Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma. Cancer Cell Int. 2017;17:94 pubmed publisher
Wong A, Searson P. Mitosis-Mediated Intravasation in a Tissue-Engineered Tumor-Microvessel Platform. Cancer Res. 2017;77:6453-6461 pubmed publisher
Brugnoli F, Grassilli S, Lanuti P, Marchisio M, Al Qassab Y, Vezzali F, et al. Up-modulation of PLC-β2 reduces the number and malignancy of triple-negative breast tumor cells with a CD133+/EpCAM+ phenotype: a promising target for preventing progression of TNBC. BMC Cancer. 2017;17:617 pubmed publisher
Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher
Ahmad G, El Sadda R, Botchkina G, Ojima I, Egan J, Amiji M. Nanoemulsion formulation of a novel taxoid DHA-SBT-1214 inhibits prostate cancer stem cell-induced tumor growth. Cancer Lett. 2017;406:71-80 pubmed publisher
Han S, Meng L, Jiang Y, Cheng W, Tie X, Xia J, et al. Lithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling. Br J Cancer. 2017;116:1302-1311 pubmed publisher
Lee J, Snyder E, Liu Y, Gu X, Wang J, Flowers B, et al. Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells. Nat Commun. 2017;8:14686 pubmed publisher
Kang T, Choi S, Yang S, Shin T, Kim H, Yu K, et al. Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule. Sci Rep. 2014;4:5546 pubmed publisher
Jelen S, Parm Ulhøi B, Larsen A, Frøkiær J, Nielsen S, Rutzler M. AQP9 expression in glioblastoma multiforme tumors is limited to a small population of astrocytic cells and CD15(+)/CalB(+) leukocytes. PLoS ONE. 2013;8:e75764 pubmed publisher
Wang L, Huang X, Zheng X, Wang X, Li S, Zhang L, et al. Enrichment of prostate cancer stem-like cells from human prostate cancer cell lines by culture in serum-free medium and chemoradiotherapy. Int J Biol Sci. 2013;9:472-9 pubmed publisher
Golden J, Shahaduzzaman M, Wabnitz A, Green S, Womble T, Sanberg P, et al. Human umbilical cord blood cells alter blood and spleen cell populations after stroke. Transl Stroke Res. 2012;3:491-9 pubmed publisher
Donnenberg A, Zimmerlin L, Landreneau R, Luketich J, Donnenberg V. KIT (CD117) expression in a subset of non-small cell lung carcinoma (NSCLC) patients. PLoS ONE. 2012;7:e52885 pubmed publisher
Kurian L, Sancho Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, et al. Conversion of human fibroblasts to angioblast-like progenitor cells. Nat Methods. 2013;10:77-83 pubmed publisher
Walton R, Parmentier T, Wolfe J. Postnatal neural precursor cell regions in the rostral subventricular zone, hippocampal subgranular zone and cerebellum of the dog (Canis lupus familiaris). Histochem Cell Biol. 2013;139:415-29 pubmed publisher
Cox J, Wilder P, Desler M, Rizzino A. Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells. PLoS ONE. 2012;7:e44087 pubmed publisher
Pfenninger C, Roschupkina T, Hertwig F, Kottwitz D, Englund E, Bengzon J, et al. CD133 is not present on neurogenic astrocytes in the adult subventricular zone, but on embryonic neural stem cells, ependymal cells, and glioblastoma cells. Cancer Res. 2007;67:5727-36 pubmed
Hawley R, Ramezani A, Hawley T. Hematopoietic stem cells. Methods Enzymol. 2006;419:149-79 pubmed
Bussolati B, Bruno S, Grange C, Buttiglieri S, Deregibus M, Cantino D, et al. Isolation of renal progenitor cells from adult human kidney. Am J Pathol. 2005;166:545-55 pubmed
Richardson G, Robson C, Lang S, Neal D, Maitland N, Collins A. CD133, a novel marker for human prostatic epithelial stem cells. J Cell Sci. 2004;117:3539-45 pubmed
Uchida N, Buck D, He D, Reitsma M, Masek M, Phan T, et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A. 2000;97:14720-5 pubmed
Gallacher L, Murdoch B, Wu D, Karanu F, Keeney M, Bhatia M. Isolation and characterization of human CD34(-)Lin(-) and CD34(+)Lin(-) hematopoietic stem cells using cell surface markers AC133 and CD7. Blood. 2000;95:2813-20 pubmed
Peichev M, Naiyer A, Pereira D, Zhu Z, Lane W, Williams M, et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood. 2000;95:952-8 pubmed
Buhring H, Seiffert M, Bock T, Scheding S, Thiel A, Scheffold A, et al. Expression of novel surface antigens on early hematopoietic cells. Ann N Y Acad Sci. 1999;872:25-38; discussion 38-9 pubmed
product information
MB Cataloge Number :
130-090-851
Catalog Number :
130-090-851
Product Name :
CD133/2 Antibody, anti-human, pure
Product Type :
Primary antibodies
Host Species :
mouse IgG2bκ
Clonality :
monoclonal
Conjugation :
pure
Antigen Modification :
CD133/2
Clone Name :
293C3
Isotype :
Isotype Control Antibody, mouse IgG2b
Size :
50 µg in 1 mL
US List Price :
253 USD
Product Description :
Detection of human stem and progenitor cells
ALTnames :
PROM1, AC133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4
Specificity :
human
Uses :
For research use only
Application Summary :
Flow cytometry
Storage :
Store protected from light at 2–8 °C. Do not freeze.
more info or order :
company information
Miltenyi Biotec
Friedrich-Ebert-Strae 68
51429 Bergisch Gladbach
macs@miltenyibiotec.com
https://www.miltenyibiotec.com
1 800 FOR MACS
headquarters: Germany