product summary
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company name :
Miltenyi Biotec
product type :
antibody
product name :
CD1c (BDCA-1) Antibody, anti-human, pure
catalog :
130-090-695
quantity :
100 µg in 1 mL
price :
160 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AD5-8E7
reactivity :
human, rhesus macaque
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 30
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig s3f
Cottineau J, Kottemann M, Lach F, Kang Y, Vély F, Deenick E, et al. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency. J Clin Invest. 2017;127:1991-2006 pubmed publisher
  • flow cytometry; human; 1:20; loading ...; fig 6f
Borriello F, Iannone R, Di Somma S, Vastolo V, Petrosino G, Visconte F, et al. Lipopolysaccharide-Elicited TSLPR Expression Enriches a Functionally Discrete Subset of Human CD14+ CD1c+ Monocytes. J Immunol. 2017;198:3426-3435 pubmed publisher
  • flow cytometry; human; tbl 1
Botting R, Bertram K, Baharlou H, Sandgren K, Fletcher J, Rhodes J, et al. Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes. J Leukoc Biol. 2017;101:1393-1403 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Sontag S, Förster M, Qin J, Wanek P, Mitzka S, Schüler H, et al. Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells. Stem Cells. 2017;35:898-908 pubmed publisher
  • flow cytometry; rhesus macaque; loading ...; fig 7c
Kasturi S, Kozlowski P, Nakaya H, Burger M, Russo P, Pham M, et al. Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5α Restrictive Macaques. J Virol. 2017;91: pubmed publisher
  • flow cytometry; human; 1:10; fig s2c
Reinisch A, Thomas D, Corces M, Zhang X, Gratzinger D, Hong W, et al. A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells. Nat Med. 2016;22:812-21 pubmed publisher
  • flow cytometry; human; 1:200; loading ...; fig 7f
Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed publisher
  • flow cytometry; human
Balan S, Ollion V, Colletti N, Chelbi R, Montanana Sanchis F, Liu H, et al. Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells. J Immunol. 2014;193:1622-35 pubmed publisher
  • immunohistochemistry - frozen section; human
Vittorakis S, Samitas K, Tousa S, Zervas E, Aggelakopoulou M, Semitekolou M, et al. Circulating conventional and plasmacytoid dendritic cell subsets display distinct kinetics during in vivo repeated allergen skin challenges in atopic subjects. Biomed Res Int. 2014;2014:231036 pubmed publisher
Rühl J, Citterio C, Engelmann C, Haigh T, Dzionek A, Dreyer J, et al. Heterologous prime-boost vaccination protects against EBV antigen-expressing lymphomas. J Clin Invest. 2019;129:2071-2087 pubmed publisher
Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed publisher
Sauss K, Ehrentraut S, Zenclussen A, Schumacher A. The pregnancy hormone human chorionic gonadotropin differentially regulates plasmacytoid and myeloid blood dendritic cell subsets. Am J Reprod Immunol. 2018;79:e12837 pubmed publisher
Delso Vallejo M, Kollet J, Koehl U, Huppert V. Influence of Irradiated Peripheral Blood Mononuclear Cells on Both Ex Vivo Proliferation of Human Natural Killer Cells and Change in Cellular Property. Front Immunol. 2017;8:854 pubmed publisher
McDonnell A, Cook A, Robinson B, Lake R, Nowak A. Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters. BMC Cancer. 2017;17:417 pubmed publisher
Krupna Gaylord M, Liveris D, Love A, Wormser G, Schwartz I, Petzke M. Induction of type I and type III interferons by Borrelia burgdorferi correlates with pathogenesis and requires linear plasmid 36. PLoS ONE. 2014;9:e100174 pubmed publisher
Vanders R, Gibson P, Murphy V, Wark P. Plasmacytoid dendritic cells and CD8 T cells from pregnant women show altered phenotype and function following H1N1/09 infection. J Infect Dis. 2013;208:1062-70 pubmed publisher
Miles B, Scisci E, CARRION J, Sabino G, Genco C, Cutler C. Noncanonical dendritic cell differentiation and survival driven by a bacteremic pathogen. J Leukoc Biol. 2013;94:281-9 pubmed publisher
Hémont C, Neel A, Heslan M, Braudeau C, Josien R. Human blood mDC subsets exhibit distinct TLR repertoire and responsiveness. J Leukoc Biol. 2013;93:599-609 pubmed publisher
CARRION J, Scisci E, Miles B, Sabino G, Zeituni A, Gu Y, et al. Microbial carriage state of peripheral blood dendritic cells (DCs) in chronic periodontitis influences DC differentiation, atherogenic potential. J Immunol. 2012;189:3178-87 pubmed publisher
Hou W, Gibbs J, Lu X, Brooke C, Roy D, Modlin R, et al. Viral infection triggers rapid differentiation of human blood monocytes into dendritic cells. Blood. 2012;119:3128-31 pubmed publisher
van de Ven R, van den Hout M, Lindenberg J, Sluijter B, van Leeuwen P, Lougheed S, et al. Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation. Blood. 2011;118:2502-10 pubmed publisher
Mittag D, Proietto A, Loudovaris T, Mannering S, Vremec D, Shortman K, et al. Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol. 2011;186:6207-17 pubmed publisher
Bosco M, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, et al. Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo. Blood. 2011;117:2625-39 pubmed publisher
Contreras V, Urien C, Guiton R, Alexandre Y, Vu Manh T, Andrieu T, et al. Existence of CD8?-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species. J Immunol. 2010;185:3313-25 pubmed publisher
Brigl M, Brenner M. CD1: antigen presentation and T cell function. Annu Rev Immunol. 2004;22:817-90 pubmed
Peiser M, Grützkau A, Wanner R, Kolde G. CD1a and CD1c cell sorting yields a homogeneous population of immature human Langerhans cells. J Immunol Methods. 2003;279:41-53 pubmed
Clark F, Freeman L, Dzionek A, Schmitz J, McMullan D, Simpson P, et al. Origin and subset distribution of peripheral blood dendritic cells in patients with chronic graft-versus-host disease. Transplantation. 2003;75:221-5 pubmed
MacDonald K, Munster D, Clark G, Dzionek A, Schmitz J, Hart D. Characterization of human blood dendritic cell subsets. Blood. 2002;100:4512-20 pubmed
Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, et al. BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol. 2000;165:6037-46 pubmed
Grabbe S, Kämpgen E, Schuler G. Dendritic cells: multi-lineal and multi-functional. Immunol Today. 2000;21:431-3 pubmed
product information
MB Cataloge Number :
130-090-695
Catalog Number :
130-090-695
Product Name :
CD1c (BDCA-1) Antibody, anti-human, pure
Product Type :
Primary antibodies
Host Species :
mouse IgG2a
Clonality :
monoclonal
Conjugation :
pure
Antigen Modification :
CD1c (BDCA-1)
Clone Name :
AD5-8E7
Isotype :
Isotype Control Antibody, mouse IgG2a
Size :
100 µg in 1 mL
US List Price :
160 USD
Product Description :
Detection of human CD1c (BDCA-1)+ myeloid dendritic cells (MDC1s), detection of non-human primate myeloid blood dendritic cells
CrossReactivity :
rhesus monkey (Macaca mulatta), cynomolgus monkey (Macaca fascicularis)
ALTnames :
BDCA-1, CD1, R7, R7, M241, T6, CD1a
Specificity :
human, non-human primate
Uses :
For research use only
Application Summary :
Flow cytometry
Storage :
Store protected from light at 2–8 °C. Do not freeze.
more info or order :
company information
Miltenyi Biotec
Friedrich-Ebert-Strae 68
51429 Bergisch Gladbach
macs@miltenyibiotec.com
https://www.miltenyibiotec.com
1 800 FOR MACS
headquarters: Germany