product summary
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company name :
Miltenyi Biotec
product type :
antibody
product name :
CD141 (BDCA-3) Antibody, anti-human, pure
catalog :
130-090-694
quantity :
100 µg in 1 mL
price :
160 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AD5-14H12
reactivity :
human
application :
flow cytometry
more info or order :
citations: 30
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 4b
Ho V, Yong H, Chevrier M, Narang V, Lum J, Toh Y, et al. RIG-I activation by a designer short RNA ligand protects human immune cells against dengue virus infection without causing cytotoxicity. J Virol. 2019;: pubmed publisher
  • flow cytometry; human; loading ...; fig 1c
Gorvel L, Korenfeld D, Tung T, Klechevsky E. Dendritic Cell-Derived IL-32?: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol. 2017;199:1290-1300 pubmed publisher
  • flow cytometry; human; loading ...; fig s4c
See P, Dutertre C, Chen J, Günther P, McGovern N, Irac S, et al. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017;356: pubmed publisher
  • flow cytometry; human; loading ...; fig st12
Villani A, Satija R, Reynolds G, Sarkizova S, Shekhar K, Fletcher J, et al. Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors. Science. 2017;356: pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Botting R, Bertram K, Baharlou H, Sandgren K, Fletcher J, Rhodes J, et al. Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes. J Leukoc Biol. 2017;101:1393-1403 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Sontag S, Förster M, Qin J, Wanek P, Mitzka S, Schüler H, et al. Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells. Stem Cells. 2017;35:898-908 pubmed publisher
  • flow cytometry; human; loading ...; fig 1b
Ju X, Silveira P, Hsu W, Elgundi Z, Alingcastre R, Verma N, et al. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population. J Immunol. 2016;197:4613-4625 pubmed
  • flow cytometry; human; loading ...
Mascarell L, Airouche S, Berjont N, Gary C, Gueguen C, Fourcade G, et al. The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammation. Mucosal Immunol. 2017;10:695-704 pubmed publisher
  • flow cytometry; human; loading ...
Cerny D, Thi Le D, The T, Zuest R, Kg S, Velumani S, et al. Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence. J Allergy Clin Immunol. 2016;138:1709-1712.e11 pubmed publisher
  • flow cytometry; human; loading ...; fig 3b
Lo T, Silveira P, Fromm P, Verma N, Vu P, Kupresanin F, et al. Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016;197:885-98 pubmed publisher
Rühl J, Citterio C, Engelmann C, Haigh T, Dzionek A, Dreyer J, et al. Heterologous prime-boost vaccination protects against EBV antigen-expressing lymphomas. J Clin Invest. 2019;129:2071-2087 pubmed publisher
Lahaye X, Gentili M, Silvin A, Conrad C, Picard L, Jouve M, et al. NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation. Cell. 2018;175:488-501.e22 pubmed publisher
Kirkling M, Cytlak U, Lau C, Lewis K, Resteu A, Khodadadi Jamayran A, et al. Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells. Cell Rep. 2018;23:3658-3672.e6 pubmed publisher
Engelmann R, Nekarda S, Kuthning D, Kneitz C, Müller Hilke B. Decreased IgG4 ACPA levels in responders and increased CD1c+ classical dendritic cells in non-responders of patients with rheumatoid arthritis under therapy. Clin Rheumatol. 2018;37:1783-1790 pubmed publisher
Sauss K, Ehrentraut S, Zenclussen A, Schumacher A. The pregnancy hormone human chorionic gonadotropin differentially regulates plasmacytoid and myeloid blood dendritic cell subsets. Am J Reprod Immunol. 2018;79:e12837 pubmed publisher
McDonnell A, Cook A, Robinson B, Lake R, Nowak A. Serial immunomonitoring of cancer patients receiving combined antagonistic anti-CD40 and chemotherapy reveals consistent and cyclical modulation of T cell and dendritic cell parameters. BMC Cancer. 2017;17:417 pubmed publisher
Jardine L, Barge D, Ames Draycott A, Pagan S, Cookson S, Spickett G, et al. Rapid detection of dendritic cell and monocyte disorders using CD4 as a lineage marker of the human peripheral blood antigen-presenting cell compartment. Front Immunol. 2013;4:495 pubmed publisher
Vanders R, Gibson P, Murphy V, Wark P. Plasmacytoid dendritic cells and CD8 T cells from pregnant women show altered phenotype and function following H1N1/09 infection. J Infect Dis. 2013;208:1062-70 pubmed publisher
Hémont C, Neel A, Heslan M, Braudeau C, Josien R. Human blood mDC subsets exhibit distinct TLR repertoire and responsiveness. J Leukoc Biol. 2013;93:599-609 pubmed publisher
Oosterhoff D, Lougheed S, van de Ven R, Lindenberg J, van Cruijsen H, Hiddingh L, et al. Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition. Oncoimmunology. 2012;1:649-658 pubmed
Dutertre C, Amraoui S, Derosa A, Jourdain J, Vimeux L, Goguet M, et al. Pivotal role of M-DC8? monocytes from viremic HIV-infected patients in TNF? overproduction in response to microbial products. Blood. 2012;120:2259-68 pubmed publisher
Chu C, Ali N, Karagiannis P, Di Meglio P, Skowera A, Napolitano L, et al. Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation. J Exp Med. 2012;209:935-45 pubmed publisher
Ghosh M, McAuliffe B, Subramani J, Basu S, Shapiro L. CD13 regulates dendritic cell cross-presentation and T cell responses by inhibiting receptor-mediated antigen uptake. J Immunol. 2012;188:5489-99 pubmed publisher
van de Ven R, van den Hout M, Lindenberg J, Sluijter B, van Leeuwen P, Lougheed S, et al. Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation. Blood. 2011;118:2502-10 pubmed publisher
Mittag D, Proietto A, Loudovaris T, Mannering S, Vremec D, Shortman K, et al. Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status. J Immunol. 2011;186:6207-17 pubmed publisher
Bosco M, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, et al. Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo. Blood. 2011;117:2625-39 pubmed publisher
Jongbloed S, Kassianos A, McDonald K, Clark G, Ju X, Angel C, et al. Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J Exp Med. 2010;207:1247-60 pubmed publisher
MacDonald K, Munster D, Clark G, Dzionek A, Schmitz J, Hart D. Characterization of human blood dendritic cell subsets. Blood. 2002;100:4512-20 pubmed
Chehimi J, Campbell D, Azzoni L, Bacheller D, Papasavvas E, Jerandi G, et al. Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals. J Immunol. 2002;168:4796-801 pubmed
Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, et al. BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol. 2000;165:6037-46 pubmed
product information
MB Cataloge Number :
130-090-694
Catalog Number :
130-090-694
Product Name :
CD141 (BDCA-3) Antibody, anti-human, pure
Product Type :
Primary antibodies
Host Species :
mouse IgG1κ
Clonality :
monoclonal
Conjugation :
pure
Antigen Modification :
CD141 (BDCA-3)
Clone Name :
AD5-14H12
Isotype :
Isotype Control Antibody, mouse IgG1
Size :
100 µg in 1 mL
US List Price :
160 USD
Product Description :
Detection of human CD141 (BDCA-3)+ type-2 myeloid dendritic cells (MDC2s)
ALTnames :
THBD, AHUS6, BDCA3, THPH12, THRM, TM
Specificity :
human
Uses :
For research use only
Application Summary :
Flow cytometry
Storage :
Store protected from light at 2–8 °C. Do not freeze.
more info or order :
company information
Miltenyi Biotec
Friedrich-Ebert-Strae 68
51429 Bergisch Gladbach
macs@miltenyibiotec.com
https://www.miltenyibiotec.com
1 800 FOR MACS
headquarters: Germany