product summary
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company name :
Miltenyi Biotec
product type :
antibody
product name :
CD133/2 Antibody, anti-human, pure
catalog :
130-090-423
quantity :
50 µg in 1 mL
price :
253 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AC141
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 2h
Jung Y, Cackowski F, Yumoto K, Decker A, Wang J, Kim J, et al. CXCL12γ Promotes Metastatic Castration-Resistant Prostate Cancer by Inducing Cancer Stem Cell and Neuroendocrine Phenotypes. Cancer Res. 2018;78:2026-2039 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 2
Lee E, Wang J, Yumoto K, Jung Y, Cackowski F, Decker A, et al. DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis. Neoplasia. 2016;18:553-66 pubmed publisher
  • immunocytochemistry; human; fig 3
Jung Y, Decker A, Wang J, Lee E, Kana L, Yumoto K, et al. Endogenous GAS6 and Mer receptor signaling regulate prostate cancer stem cells in bone marrow. Oncotarget. 2016;7:25698-711 pubmed publisher
Božić T, Frobel J, Raic A, Ticconi F, Kuo C, Heilmann Heimbach S, et al. Variants of DNMT3A cause transcript-specific DNA methylation patterns and affect hematopoiesis. Life Sci Alliance. 2018;1:e201800153 pubmed publisher
Zanotti L, Romani C, Tassone L, Todeschini P, Tassi R, Bandiera E, et al. MAL gene overexpression as a marker of high-grade serous ovarian carcinoma stem-like cells that predicts chemoresistance and poor prognosis. BMC Cancer. 2017;17:366 pubmed publisher
Lai J, Cai Q, Biel M, Wang C, Hu X, Wang S, et al. Id1 and NF-?B promote the generation of CD133+ and BMI-1+ keratinocytes and the growth of xenograft tumors in mice. Int J Oncol. 2014;44:1481-9 pubmed publisher
Pötgens A, Schmitz U, Kaufmann P, Frank H. Monoclonal antibody CD133-2 (AC141) against hematopoietic stem cell antigen CD133 shows crossreactivity with cytokeratin 18. J Histochem Cytochem. 2002;50:1131-4 pubmed
Piechaczek C. CD133. J Biol Regul Homeost Agents. 2001;15:101-2 pubmed
Uchida N, Buck D, He D, Reitsma M, Masek M, Phan T, et al. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A. 2000;97:14720-5 pubmed
Gehling U, Ergun S, Schumacher U, Wagener C, Pantel K, Otte M, et al. In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood. 2000;95:3106-12 pubmed
Gallacher L, Murdoch B, Wu D, Karanu F, Keeney M, Bhatia M. Isolation and characterization of human CD34(-)Lin(-) and CD34(+)Lin(-) hematopoietic stem cells using cell surface markers AC133 and CD7. Blood. 2000;95:2813-20 pubmed
Corbeil D, Roper K, Hellwig A, Tavian M, Miraglia S, Watt S, et al. The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions. J Biol Chem. 2000;275:5512-20 pubmed
Peichev M, Naiyer A, Pereira D, Zhu Z, Lane W, Williams M, et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood. 2000;95:952-8 pubmed
Buhring H, Seiffert M, Bock T, Scheding S, Thiel A, Scheffold A, et al. Expression of novel surface antigens on early hematopoietic cells. Ann N Y Acad Sci. 1999;872:25-38; discussion 38-9 pubmed
product information
MB Cataloge Number :
130-090-423
Catalog Number :
130-090-423
Product Name :
CD133/2 Antibody, anti-human, pure
Product Type :
Primary antibodies
Host Species :
mouse IgG1
Clonality :
monoclonal
Conjugation :
pure
Antigen Modification :
CD133/2
Clone Name :
AC141
Isotype :
Isotype Control Antibody, mouse IgG1
Size :
50 µg in 1 mL
US List Price :
253 USD
Product Description :
Detection of human stem and progenitor cells
ALTnames :
PROM1, AC133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4
Specificity :
human
Uses :
For research use only
Application Summary :
Flow cytometry
Storage :
Store protected from light at 2–8 °C. Do not freeze.
more info or order :
company information
Miltenyi Biotec
Friedrich-Ebert-Strae 68
51429 Bergisch Gladbach
macs@miltenyibiotec.com
https://www.miltenyibiotec.com
1 800 FOR MACS
headquarters: Germany