product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-TOMM20 antibody produced in mouse
catalog :
WH0009804M1
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4F3
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3d
Zheng J, Croteau D, Bohr V, Akbari M. Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells. Nucleic Acids Res. 2019;: pubmed publisher
  • western blot; mouse; fig 1
Jiang H, Kang S, Zhang S, Karuppagounder S, Xu J, Lee Y, et al. Adult Conditional Knockout of PGC-1? Leads to Loss of Dopamine Neurons. Eneuro. 2016;3: pubmed publisher
  • western blot; human; 1:500; fig 5
Onesto E, Colombrita C, Gumina V, Borghi M, Dusi S, Doretti A, et al. Gene-specific mitochondria dysfunctions in human TARDBP and C9ORF72 fibroblasts. Acta Neuropathol Commun. 2016;4:47 pubmed publisher
  • immunocytochemistry; mouse
Riquelme S, Pogu J, Anegon I, Bueno S, Kalergis A. Carbon monoxide impairs mitochondria-dependent endosomal maturation and antigen presentation in dendritic cells. Eur J Immunol. 2015;45:3269-88 pubmed publisher
  • immunoprecipitation; mouse
  • immunocytochemistry; mouse
Gorbunov N, McDaniel D, Zhai M, Liao P, Garrison B, Kiang J. Autophagy and mitochondrial remodelling in mouse mesenchymal stromal cells challenged with Staphylococcus epidermidis. J Cell Mol Med. 2015;19:1133-50 pubmed publisher
  • flow cytometry; mouse; fig 5
  • immunocytochemistry; mouse; fig 5
Roy S, Stevens M, So L, Edinger A. Reciprocal effects of rab7 deletion in activated and neglected T cells. Autophagy. 2013;9:1009-23 pubmed publisher
Krause K, Daily K, Estfanous S, Hamilton K, Badr A, Abu Khweek A, et al. Caspase-11 counteracts mitochondrial ROS-mediated clearance of Staphylococcus aureus in macrophages. EMBO Rep. 2019;20:e48109 pubmed publisher
Martorano L, Peron M, Laquatra C, Lidron E, Facchinello N, Meneghetti G, et al. The zebrafish orthologue of the human hepatocerebral disease gene MPV17 plays pleiotropic roles in mitochondria. Dis Model Mech. 2019;: pubmed publisher
Marcassa E, Kallinos A, Jardine J, Rusilowicz Jones E, Martinez A, Kuehl S, et al. Dual role of USP30 in controlling basal pexophagy and mitophagy. EMBO Rep. 2018;19: pubmed publisher
Richter K, Revelo N, Seitz K, Helm M, Sarkar D, Saleeb R, et al. Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO J. 2018;37:139-159 pubmed publisher
Williamson J, Petralia R, Wang Y, Mattson M, Yao P. Purine Biosynthesis Enzymes in Hippocampal Neurons. Neuromolecular Med. 2017;19:518-524 pubmed publisher
Lee W, Higuchi H, Ikeda S, Macke E, Takimoto T, Pattnaik B, et al. Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. elife. 2016;5: pubmed publisher
Yang K, Ma X, Liu H, Murphy J, Barger P, Mann D, et al. Tumor necrosis factor receptor-associated factor 2 mediates mitochondrial autophagy. Circ Heart Fail. 2015;8:175-87 pubmed publisher
Zuo W, Zhang S, Xia C, Guo X, He W, Chen N. Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: the role of inhibition of Drp1 in ischemic brain damage. Neuropharmacology. 2014;86:103-15 pubmed publisher
Zhao Z, Han F, He Y, Yang S, Hua L, Wu J, et al. Stromal-epithelial metabolic coupling in gastric cancer: stromal MCT4 and mitochondrial TOMM20 as poor prognostic factors. Eur J Surg Oncol. 2014;40:1361-8 pubmed publisher
Saka S, Vogts A, Kr hnert K, Hillion F, Rizzoli S, Wessels J. Correlated optical and isotopic nanoscopy. Nat Commun. 2014;5:3664 pubmed publisher
Balaker A, Ishiyama P, Lopez I, Ishiyama G, Ishiyama A. Immunocytochemical localization of the translocase of the outer mitochondrial membrane (Tom20) in the human cochlea. Anat Rec (Hoboken). 2013;296:326-32 pubmed publisher
Tada M, Kanai F, Tanaka Y, Sanada M, Nannya Y, Tateishi K, et al. Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer. Cancer Sci. 2010;101:1261-9 pubmed publisher
Blesa J, Prieto Ruiz J, Hernandez J, Hernández Yago J. NRF-2 transcription factor is required for human TOMM20 gene expression. Gene. 2007;391:198-208 pubmed
Hernandez J, Giner P, Hernandez Yago J. Gene structure of the human mitochondrial outer membrane receptor Tom20 and evolutionary study of its family of processed pseudogenes. Gene. 1999;239:283-91 pubmed
Schleiff E, Turnbull J. Characterization of the N-terminal targeting signal binding domain of the mitochondrial outer membrane receptor, Tom20. Biochemistry. 1998;37:13052-8 pubmed
product information
Product No. :
WH0009804M1
Product Name :
Monoclonal Anti-TOMM20 antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
4F3
Applications/Description :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections); western blot: 1-5 μg/mL; indirect immunofluorescence; indirect ELISA
Species Reactivity :
mouse, rat, human
Isotype :
IgG1κ
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA