Anti-WRN antibody, Mouse monoclonal | MilliporeSigma W0393 product information

product summary

company name :

MilliporeSigma

other brands :

FLUKA, Sigma-Aldrich, Roche Applied Science

product type :

antibody

product name :

Anti-WRN antibody, Mouse monoclonal

catalog :

W0393

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

195C

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

MilliporeSigma product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:200; loading ...; fig e8c	Chan E, Shibue T, McFarland J, Gaeta B, Ghandi M, Dumont N, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019;568:551-556 pubmed publisher
western blot; human; loading ...; fig 2c	Amalnath S, Sargolzaeiaval F, Oshima J, Baskar D. Uncommon cause of cirrhosis-A case of Werner syndrome with a novel WRN mutation. Indian J Gastroenterol. 2017;36:323-325 pubmed publisher
western blot; human; loading ...; fig 3f	Kehrli K, Phelps M, Lazarchuk P, Chen E, Monnat R, Sidorova J. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. J Biol Chem. 2016;291:24487-24503 pubmed
western blot; human; loading ...; fig 2a	Bosch L, Luo Y, Lao V, Snaebjornsson P, Trooskens G, Vlassenbroeck I, et al. WRN Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy. Clin Cancer Res. 2016;22:4612-22 pubmed publisher

product information

Product No. :

W0393

Product Name :

Anti-WRN antibody, Mouse monoclonal

Host :

mouse

Conjugate :

unconjugated

Antibody Type :

monoclonal

Clone Number (if monoclonal) :

195C

Applications/Description :

Suitable for immunohistochemistry; western blot: 2-4 μg/mL using nuclear cell extract of HeLa cells; indirect ELISA; immunoprecipitation (IP)

Species Reactivity :

human

Isotype :

IgG1

Concentration :

~1 mg/mL

Storage :

Store at -20°C

more info or order :

MilliporeSigma product webpage