product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Anti-Vinculin antibody, Mouse monoclonal
catalog :
V9264
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
hVIN-1
reactivity :
African green monkey, human, mouse, rat, dogs, chicken, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 299
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:5000; loading ...; fig s3-1b
Crespo M, González Terán B, Nikolic I, Mora A, Folgueira C, Rodriguez E, et al. Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism. elife. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig s6a
Lundby A, Franciosa G, Emdal K, Refsgaard J, Gnosa S, Bekker Jensen D, et al. Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell. 2019;179:543-560.e26 pubmed publisher
  • western blot; human; 1:2000; fig 2c
Carvalho J, Fortunato I, Fonseca C, Pezzarossa A, Barbacena P, Domínguez Cejudo M, et al. Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:10,000; loading ...; fig 1a
Araiz C, Yan A, Bettedi L, Samuelson I, Virtue S, McGavigan A, et al. Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue. Nat Commun. 2019;10:1546 pubmed publisher
  • western blot; human; loading ...; fig 4b
Gentili M, Lahaye X, Nadalin F, Nader G, Puig Lombardi E, Hervé S, et al. The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus. Cell Rep. 2019;26:2377-2393.e13 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3b
Martin V, Chiriaco C, Modica C, Acquadro A, Cortese M, Galimi F, et al. Met inhibition revokes IFNγ-induction of PD-1 ligands in MET-amplified tumours. Br J Cancer. 2019;120:527-536 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 1e
Schlenner S, Pasciuto E, Lagou V, Burton O, Prezzemolo T, Junius S, et al. NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology. Ann Rheum Dis. 2019;78:342-349 pubmed publisher
  • western blot; human; loading ...; fig 2c, s3b, s4d, s12b
Gerber T, Murawala P, Knapp D, Masselink W, Schuez M, Hermann S, et al. Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration. Science. 2018;362: pubmed publisher
  • western blot; human; fig s3a
Ong D, Hu B, Ho Y, Sauvé C, Bristow C, Wang Q, et al. PAF promotes stemness and radioresistance of glioma stem cells. Proc Natl Acad Sci U S A. 2017;114:E9086-E9095 pubmed publisher
  • western blot; human; loading ...; fig 3c
Joachim J, Razi M, Judith D, Wirth M, Calamita E, Encheva V, et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr Biol. 2017;27:2123-2136.e7 pubmed publisher
  • western blot; mouse; loading ...; fig s2f
Emmett M, Lim H, Jager J, Richter H, Adlanmerini M, Peed L, et al. Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Nature. 2017;546:544-548 pubmed publisher
  • western blot; mouse; 1:10,000; loading ...; fig 7c
Olvedy M, Tisserand J, Luciani F, Boeckx B, Wouters J, Lopez S, et al. Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma. J Clin Invest. 2017;127:2310-2325 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 1a
Cain S, Mularczyk E, Singh M, Massam Wu T, Kielty C. ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions. Sci Rep. 2016;6:35956 pubmed publisher
  • western blot; human; 1:5000; fig 5a
King B, Boccalatte F, Moran Crusio K, Wolf E, Wang J, Kayembe C, et al. The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells. Nat Immunol. 2016;17:1312-1321 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7a
  • immunocytochemistry; human; loading ...; fig 3e
Binamé F, Bidaud Meynard A, Magnan L, Piquet L, Montibus B, Chabadel A, et al. Cancer-associated mutations in the protrusion-targeting region of p190RhoGAP impact tumor cell migration. J Cell Biol. 2016;214:859-73 pubmed publisher
  • immunocytochemistry; rat; fig 1
Harizanova J, Fermin Y, Malik Sheriff R, Wieczorek J, Ickstadt K, Grecco H, et al. Highly Multiplexed Imaging Uncovers Changes in Compositional Noise within Assembling Focal Adhesions. PLoS ONE. 2016;11:e0160591 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 4d
Ryskamp D, Frye A, Phuong T, Yarishkin O, Jo A, Xu Y, et al. TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye. Sci Rep. 2016;6:30583 pubmed publisher
  • western blot; mouse; 1:6000; fig 1
  • western blot; rat; 1:6000; fig 1
  • western blot; human; 1:6000; fig 1
Stammler A, Lüftner B, Kliesch S, Weidner W, Bergmann M, Middendorff R, et al. Highly Conserved Testicular Localization of Claudin-11 in Normal and Impaired Spermatogenesis. PLoS ONE. 2016;11:e0160349 pubmed publisher
  • western blot; mouse; fig 2
Kudová J, Prochazkova J, Vašíček O, Perecko T, Sedláčková M, Pesl M, et al. HIF-1alpha Deficiency Attenuates the Cardiomyogenesis of Mouse Embryonic Stem Cells. PLoS ONE. 2016;11:e0158358 pubmed publisher
  • immunocytochemistry; rat; loading ...; fig 2c
Boateng L, Bennin D, de Oliveira S, Huttenlocher A. Mammalian Actin-binding Protein-1/Hip-55 Interacts with FHL2 and Negatively Regulates Cell Invasion. J Biol Chem. 2016;291:13987-98 pubmed publisher
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 5
Senda Y, Murata Kamiya N, Hatakeyama M. C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility. Cancer Sci. 2016;107:972-80 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 1
Elosegui Artola A, Oria R, Chen Y, Kosmalska A, Pérez González C, Castro N, et al. Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity. Nat Cell Biol. 2016;18:540-8 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Obino D, Farina F, Malbec O, Sáez P, Maurin M, Gaillard J, et al. Actin nucleation at the centrosome controls lymphocyte polarity. Nat Commun. 2016;7:10969 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig 4
Skardal A, Devarasetty M, Forsythe S, Atala A, Soker S. A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening. Biotechnol Bioeng. 2016;113:2020-32 pubmed publisher
  • western blot; human; fig 2
Baietti M, Simíček M, Abbasi Asbagh L, Radaelli E, Lievens S, Crowther J, et al. OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination. EMBO Mol Med. 2016;8:288-303 pubmed publisher
  • western blot; human; loading ...; fig 2d
Haikala H, Klefström J, Eilers M, Wiese K. MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures. Cell Cycle. 2016;15:316-23 pubmed publisher
  • western blot; human; fig 1
Kumar J, Wei B, Madigan J, Simpson R, Hall M, Gottesman M. Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier. Sci Rep. 2016;6:20418 pubmed publisher
  • western blot; human; fig 1c
Heir P, Srikumar T, Bikopoulos G, Bunda S, Poon B, Lee J, et al. Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling. J Biol Chem. 2016;291:7357-72 pubmed publisher
  • western blot; human; fig 1
Grassilli E, Pisano F, Cialdella A, Bonomo S, Missaglia C, Cerrito M, et al. A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation. Oncogene. 2016;35:4368-78 pubmed publisher
  • western blot; mouse; fig 5
Giampietro C, Disanza A, Bravi L, Barrios Rodiles M, Corada M, Frittoli E, et al. The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling. J Cell Biol. 2015;211:1177-92 pubmed publisher
  • immunocytochemistry; human; 1:50; loading ...; fig 1a
Tojkander S, Gateva G, Husain A, Krishnan R, Lappalainen P. Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly. elife. 2015;4:e06126 pubmed publisher
  • western blot; mouse; 1:10,000; fig 3
  • western blot; human; 1:10,000; fig 1
Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, et al. Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis. Nat Commun. 2015;6:8859 pubmed publisher
  • western blot; mouse; fig 3b
Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, et al. KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. EMBO Mol Med. 2016;8:6-24 pubmed publisher
  • western blot; human; 1:1000; fig 2
Harley M, Murina O, Leitch A, Higgs M, Bicknell L, Yigit G, et al. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nat Genet. 2016;48:36-43 pubmed publisher
  • western blot; human; fig s8
García Rubio M, Pérez Calero C, Barroso S, Tumini E, Herrera Moyano E, Rosado I, et al. The Fanconi Anemia Pathway Protects Genome Integrity from R-loops. PLoS Genet. 2015;11:e1005674 pubmed publisher
  • western blot; mouse; fig 3
Freedman T, Tan Y, Skrzypczynska K, Manz B, Sjaastad F, Goodridge H, et al. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. elife. 2015;4: pubmed publisher
  • western blot; human; 1:10,000; fig 3a
Setti M, Osti D, Richichi C, Ortensi B, Del Bene M, Fornasari L, et al. Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth. Oncotarget. 2015;6:31413-27 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3c
Leyme A, Marivin A, Perez Gutierrez L, Nguyen L, Garcia Marcos M. Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin. J Cell Biol. 2015;210:1165-84 pubmed publisher
  • western blot; human; 1:1000; fig 2
Haraguchi M, Sato M, Ozawa M. CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells. PLoS ONE. 2015;10:e0132260 pubmed publisher
  • immunocytochemistry; rat; fig 5c
Jiang J, Zhang Z, Yuan X, Poo M. Spatiotemporal dynamics of traction forces show three contraction centers in migratory neurons. J Cell Biol. 2015;209:759-74 pubmed publisher
  • immunocytochemistry; human
Koh L, Ng B, Bertrand J, Thierry F. Transcriptional control of late differentiation in human keratinocytes by TAp63 and Notch. Exp Dermatol. 2015;24:754-60 pubmed publisher
  • immunohistochemistry; human; 1:200
Skardal A, Devarasetty M, Rodman C, Atala A, Soker S. Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro. Ann Biomed Eng. 2015;43:2361-73 pubmed publisher
  • western blot; human
Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed publisher
  • western blot; human
Ng D, Humphries J, Byron A, Millon Frémillon A, Humphries M. Microtubule-dependent modulation of adhesion complex composition. PLoS ONE. 2014;9:e115213 pubmed publisher
  • immunocytochemistry; African green monkey; fig s2c
Boucrot E, Ferreira A, Almeida Souza L, Debard S, Vallis Y, Howard G, et al. Endophilin marks and controls a clathrin-independent endocytic pathway. Nature. 2015;517:460-5 pubmed publisher
  • immunocytochemistry; mouse
Elloumi Hannachi I, García J, Shekeran A, García A. Contributions of the integrin β1 tail to cell adhesive forces. Exp Cell Res. 2015;332:212-22 pubmed publisher
  • immunocytochemistry; rat
Sazonova O, Isenberg B, Herrmann J, Lee K, Purwada A, Valentine A, et al. Extracellular matrix presentation modulates vascular smooth muscle cell mechanotransduction. Matrix Biol. 2015;41:36-43 pubmed publisher
  • western blot; mouse; 1:15000
Kararigas G, Fliegner D, Forler S, Klein O, Schubert C, Gustafsson J, et al. Comparative proteomic analysis reveals sex and estrogen receptor β effects in the pressure overloaded heart. J Proteome Res. 2014;13:5829-36 pubmed publisher
  • western blot; human
Raman N, Nayak A, Muller S. mTOR signaling regulates nucleolar targeting of the SUMO-specific isopeptidase SENP3. Mol Cell Biol. 2014;34:4474-84 pubmed publisher
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 6
  • immunocytochemistry; African green monkey; fig s1
Chang Y, Huang Y. Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. PLoS ONE. 2014;9:e107961 pubmed publisher
  • immunocytochemistry; human
Rubashkin M, Cassereau L, Bainer R, DuFort C, Yui Y, Ou G, et al. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014;74:4597-611 pubmed publisher
  • immunocytochemistry; human
Pryzhkova M, Aria I, Cheng Q, Harris G, Zan X, Gharib M, et al. Carbon nanotube-based substrates for modulation of human pluripotent stem cell fate. Biomaterials. 2014;35:5098-109 pubmed publisher
  • immunohistochemistry; rat; 1:500
Uehara K, Uehara A. Integrin ?v?5 in endothelial cells of rat splenic sinus: an immunohistochemical and ultrastructural study. Cell Tissue Res. 2014;356:183-93 pubmed publisher
  • immunocytochemistry; human; 5 ug/ml; fig 2
Georgess D, Mazzorana M, Terrado J, Delprat C, Chamot C, Guasch R, et al. Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts. Mol Biol Cell. 2014;25:380-96 pubmed publisher
  • immunocytochemistry; mouse
  • immunocytochemistry; rat
  • immunocytochemistry; human
Juin A, Planus E, Guillemot F, Horáková P, Albiges Rizo C, Genot E, et al. Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells. Biol Cell. 2013;105:46-57 pubmed publisher
Chrysostomou S, Roy R, Prischi F, Thamlikitkul L, Chapman K, Mufti U, et al. Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. Sci Transl Med. 2021;13: pubmed publisher
Munoz P, Tristán Manzano M, Sanchez Gilabert A, Santilli G, Galy A, Thrasher A, et al. WAS Promoter-Driven Lentiviral Vectors Mimic Closely the Lopsided WASP Expression during Megakaryocytic Differentiation. Mol Ther Methods Clin Dev. 2020;19:220-235 pubmed publisher
Parry D, Tamayo Orrego L, Carroll P, Marsh J, Greene P, Murina O, et al. PRIM1 deficiency causes a distinctive primordial dwarfism syndrome. Genes Dev. 2020;: pubmed publisher
Chen K, Jiao X, Di Rocco A, Shen D, Xu S, Ertel A, et al. Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation. Cell Rep. 2020;32:108151 pubmed publisher
Schuld J, Orfanos Z, Chevessier F, Eggers B, Heil L, Uszkoreit J, et al. Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation. Acta Neuropathol Commun. 2020;8:154 pubmed publisher
Whitelaw J, Swaminathan K, Kage F, Machesky L. The WAVE Regulatory Complex Is Required to Balance Protrusion and Adhesion in Migration. Cells. 2020;9: pubmed publisher
Damiano Guercio J, Kurzawa L, Mueller J, Dimchev G, Schaks M, Nemethova M, et al. Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion. elife. 2020;9: pubmed publisher
Rickman K, Noonan R, Lach F, Sridhar S, Wang A, Abhyankar A, et al. Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links. Genes Dev. 2020;34:832-846 pubmed publisher
Sriskandarajah P, de Haven Brandon A, MacLeod K, Carragher N, Kirkin V, Kaiser M, et al. Combined targeting of MEK and the glucocorticoid receptor for the treatment of RAS-mutant multiple myeloma. BMC Cancer. 2020;20:269 pubmed publisher
Panciera T, Citron A, Di Biagio D, Battilana G, Gandin A, Giulitti S, et al. Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties. Nat Mater. 2020;19:797-806 pubmed publisher
McCann J, Vasilevskaya I, Poudel Neupane N, Shafi A, McNair C, Dylgjeri E, et al. USP22 Functions as an Oncogenic Driver in Prostate Cancer by Regulating Cell Proliferation and DNA Repair. Cancer Res. 2020;80:430-443 pubmed publisher
Jain P, Guerreiro P, Canato S, Janody F. The spectraplakin Dystonin antagonizes YAP activity and suppresses tumourigenesis. Sci Rep. 2019;9:19843 pubmed publisher
Bueno M, Jimenez Renard V, Samino S, Capellades J, Junza A, López Rodríguez M, et al. Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells. Nat Commun. 2019;10:5011 pubmed publisher
Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger J, Busch A, et al. The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol. 2019;20:216 pubmed publisher
Re Cecconi A, Forti M, Chiappa M, Zhu Z, Zingman L, Cervo L, et al. Musclin, A Myokine Induced by Aerobic Exercise, Retards Muscle Atrophy During Cancer Cachexia in Mice. Cancers (Basel). 2019;11: pubmed publisher
Saleh A, Marhuenda E, Fabre C, Hassani Z, Weille J, Boukhaddaoui H, et al. A novel 3D nanofibre scaffold conserves the plasticity of glioblastoma stem cell invasion by regulating galectin-3 and integrin-β1 expression. Sci Rep. 2019;9:14612 pubmed publisher
Agabiti S, Li J, Dong W, Poe M, Wiemer A. Regulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition. Cell Death Dis. 2019;10:733 pubmed publisher
Gomes A, Ilter D, Low V, Rosenzweig A, Shen Z, Schild T, et al. Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization. Cancer Cell. 2019;36:402-417.e13 pubmed publisher
Cao P, Wang Y, Lv Y, Jiang N, Zhong L, Ma X, et al. PI3K p110α inhibition sensitizes cervical cancer cells with aberrant PI3K signaling activation to PARP inhibitor BMN673. Oncol Rep. 2019;42:2097-2107 pubmed publisher
Chandorkar Y, Castro Nava A, Schweizerhof S, Van Dongen M, Haraszti T, Köhler J, et al. Cellular responses to beating hydrogels to investigate mechanotransduction. Nat Commun. 2019;10:4027 pubmed publisher
Ferrié C, Kasper S, Wanivenhaus F, Fluck M. Time course of costamere-related alterations in focal adhesion signaling and composition of rat soleus muscle after achilles tenotomy. Data Brief. 2019;25:103999 pubmed publisher
Salas Armenteros I, Barroso S, Rondon A, Perez M, Andújar E, Luna R, et al. Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability. Cell Rep. 2019;28:1551-1563.e7 pubmed publisher
Gryder B, Wu L, Woldemichael G, Pomella S, Quinn T, Park P, et al. Chemical genomics reveals histone deacetylases are required for core regulatory transcription. Nat Commun. 2019;10:3004 pubmed publisher
Bax N, Duim S, Kruithof B, Smits A, Bouten C, Goumans M. In vivo and in vitro Approaches Reveal Novel Insight Into the Ability of Epicardium-Derived Cells to Create Their Own Extracellular Environment. Front Cardiovasc Med. 2019;6:81 pubmed publisher
Dylgjeri E, McNair C, Goodwin J, Raymon H, McCue P, Shafi A, et al. Pleiotropic Impact of DNA-PK in Cancer and Implications for Therapeutic Strategies. Clin Cancer Res. 2019;25:5623-5637 pubmed publisher
Lionarons D, Hancock D, Rana S, East P, Moore C, Murillo M, et al. RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance. Cancer Cell. 2019;: pubmed publisher
Malinverno M, Maderna C, Abu Taha A, Corada M, Orsenigo F, Valentino M, et al. Endothelial cell clonal expansion in the development of cerebral cavernous malformations. Nat Commun. 2019;10:2761 pubmed publisher
Chan C, Costanzo M, Ruiz Herrero T, Mönke G, Petrie R, Bergert M, et al. Hydraulic control of mammalian embryo size and cell fate. Nature. 2019;: pubmed publisher
Chu B, Kon N, Chen D, Li T, Liu T, Jiang L, et al. ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway. Nat Cell Biol. 2019;21:579-591 pubmed publisher
Linnane E, Davey P, Zhang P, Puri S, Edbrooke M, Chiarparin E, et al. Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines. Nucleic Acids Res. 2019;47:4375-4392 pubmed publisher
Ferrié C, Kasper S, Wanivenhaus F, Fluck M. Focal adhesion kinase coordinates costamere-related JNK signaling with muscle fiber transformation after Achilles tenotomy and tendon reconstruction. Exp Mol Pathol. 2019;108:42-56 pubmed publisher
Wang W, Davidson C, Lin D, Baker B. Actomyosin contractility-dependent matrix stretch and recoil induces rapid cell migration. Nat Commun. 2019;10:1186 pubmed publisher
Roh J, Hobson R, Chaudhari V, Quintero P, Yeri A, Benson M, et al. Activin type II receptor signaling in cardiac aging and heart failure. Sci Transl Med. 2019;11: pubmed publisher
Meléndez Rodríguez F, Urrutia A, Lorendeau D, Rinaldi G, Roche O, Böğürcü Seidel N, et al. HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis. Cell Rep. 2019;26:2257-2265.e4 pubmed publisher
Cait J, Hughes M, Zeglinski M, Chan A, Osterhof S, Scott R, et al. Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Losier T, Akuma M, McKee Muir O, LeBlond N, Suk Y, Alsaadi R, et al. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Rep. 2019;26:2150-2165.e5 pubmed publisher
Bunda S, Heir P, Metcalf J, Li A, Agnihotri S, Pusch S, et al. CIC protein instability contributes to tumorigenesis in glioblastoma. Nat Commun. 2019;10:661 pubmed publisher
Liu T, Jiang L, Tavana O, Gu W. The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11. Cancer Res. 2019;79:1913-1924 pubmed publisher
Sartori Rupp A, Cordero Cervantes D, Pepe A, Gousset K, Delage E, Corroyer Dulmont S, et al. Correlative cryo-electron microscopy reveals the structure of TNTs in neuronal cells. Nat Commun. 2019;10:342 pubmed publisher
Leinhos L, Peters J, Krull S, Helbig L, Vogler M, Lévay M, et al. Hypoxia suppresses myofibroblast differentiation by changing RhoA activity. J Cell Sci. 2019;132: pubmed publisher
Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D Elia E, et al. p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value. Cell Rep. 2019;26:624-638.e8 pubmed publisher
Kano Y, Gebregiworgis T, Marshall C, Radulovich N, Poon B, St Germain J, et al. Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation. Nat Commun. 2019;10:224 pubmed publisher
Hino N, Ichikawa T, Kimura Y, Matsuda M, Ueda K, Kioka N. An amphipathic helix of vinexin α is necessary for a substrate stiffness-dependent conformational change in vinculin. J Cell Sci. 2019;132: pubmed publisher
Horné F, Dietze R, Berkes E, Oehmke F, Tinneberg H, Meinhold Heerlein I, et al. Impaired Localization of Claudin-11 in Endometriotic Epithelial Cells Compared to Endometrial Cells. Reprod Sci. 2019;26:1181-1192 pubmed publisher
Wang W, Pearson A, Kutys M, Choi C, Wozniak M, Baker B, et al. Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration. APL Bioeng. 2018;2:046107 pubmed publisher
De Luca E, Pedone D, Moglianetti M, Pulcini D, Perrelli A, Retta S, et al. Multifunctional Platinum@BSA-Rapamycin Nanocarriers for the Combinatorial Therapy of Cerebral Cavernous Malformation. ACS Omega. 2018;3:15389-15398 pubmed publisher
Bainor A, Saini S, Calderon A, Casado Polanco R, Giner Ramirez B, Moncada C, et al. The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Cell Rep. 2018;25:2797-2807.e8 pubmed publisher
Serresi M, Siteur B, Hulsman D, Company C, Schmitt M, Lieftink C, et al. Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities. J Exp Med. 2018;215:3115-3135 pubmed publisher
Vaynberg J, Fukuda K, Lu F, Bialkowska K, Chen Y, Plow E, et al. Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion. Nat Commun. 2018;9:4465 pubmed publisher
Cabron A, El Azzouzi K, Boss M, Arnold P, Schwarz J, Rosas M, et al. Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells. J Immunol. 2018;201:3106-3118 pubmed publisher
Smith T, Saul R, Barton E, Luna E. Generation and characterization of monoclonal antibodies that recognize human and murine supervillin protein isoforms. PLoS ONE. 2018;13:e0205910 pubmed publisher
Georgess D, Spuul P, Le Clainche C, Le Nihouannen D, Fremaux I, Dakhli T, et al. Anti-osteoclastic effects of C-glucosidic ellagitannins mediated by actin perturbation. Eur J Cell Biol. 2018;97:533-545 pubmed publisher
Lahaye X, Gentili M, Silvin A, Conrad C, Picard L, Jouve M, et al. NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation. Cell. 2018;175:488-501.e22 pubmed publisher
Pieuchot L, Marteau J, Guignandon A, Dos Santos T, Brigaud I, Chauvy P, et al. Curvotaxis directs cell migration through cell-scale curvature landscapes. Nat Commun. 2018;9:3995 pubmed publisher
Kaasbøll O, Gadicherla A, Wang J, Monsen V, Hagelin E, Dong M, et al. Connective tissue growth factor (CCN2) is a matricellular preproprotein controlled by proteolytic activation. J Biol Chem. 2018;293:17953-17970 pubmed publisher
Román García S, Merino Cortes S, Gardeta S, de Bruijn M, Hendriks R, Carrasco Y. Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation. Front Immunol. 2018;9:2027 pubmed publisher
Wang Y, Chen S, Colborne S, Lambert G, Shin C, Santos N, et al. Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type. Mol Cancer Ther. 2018;17:2767-2779 pubmed publisher
Albers E, Sbroggiò M, Pladevall Morera D, Bizard A, Avram A, Gonzalez P, et al. Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality. Cell Rep. 2018;24:3274-3284 pubmed publisher
Andriani F, Landoni E, Mensah M, Facchinetti F, Miceli R, Tagliabue E, et al. Diagnostic role of circulating extracellular matrix-related proteins in non-small cell lung cancer. BMC Cancer. 2018;18:899 pubmed publisher
Zhu S, Bhat S, Syan S, Kuchitsu Y, Fukuda M, Zurzolo C. Rab11a-Rab8a cascade regulates the formation of tunneling nanotubes through vesicle recycling. J Cell Sci. 2018;131: pubmed publisher
Hangas A, Aasumets K, Kekäläinen N, Paloheinä M, Pohjoismäki J, Gerhold J, et al. Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2. Nucleic Acids Res. 2018;46:9625-9636 pubmed publisher
Laustsen A, Bak R, Krapp C, Kjær L, Egedahl J, Petersen C, et al. Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function. Nat Commun. 2018;9:3525 pubmed publisher
Tarade D, Robinson C, Lee J, Ohh M. HIF-2α-pVHL complex reveals broad genotype-phenotype correlations in HIF-2α-driven disease. Nat Commun. 2018;9:3359 pubmed publisher
Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, et al. Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response. Nat Med. 2018;24:1550-1558 pubmed publisher
Ikonomov O, Altankov G, Sbrissa D, Shisheva A. PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation. Toxicol Appl Pharmacol. 2018;356:151-158 pubmed publisher
Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed publisher
Zimmermann M, Murina O, Reijns M, Agathanggelou A, Challis R, Tarnauskaitė Ž, et al. CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions. Nature. 2018;559:285-289 pubmed publisher
Tojkander S, Ciuba K, Lappalainen P. CaMKK2 Regulates Mechanosensitive Assembly of Contractile Actin Stress Fibers. Cell Rep. 2018;24:11-19 pubmed publisher
Benitez Guijarro M, Lopez Ruiz C, Tarnauskaitė Ž, Murina O, Mian Mohammad M, Williams T, et al. RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition. EMBO J. 2018;37: pubmed publisher
Viswanathan S, Nogueira M, Buss C, Krill Burger J, Wawer M, Malolepsza E, et al. Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer. Nat Genet. 2018;50:937-943 pubmed publisher
Jones M, Askari J, Humphries J, Humphries M. Cell adhesion is regulated by CDK1 during the cell cycle. J Cell Biol. 2018;217:3203-3218 pubmed publisher
Lee S, Kassianidou E, Kumar S. Actomyosin stress fiber subtypes have unique viscoelastic properties and roles in tension generation. Mol Biol Cell. 2018;29:1992-2004 pubmed publisher
Sakthianandeswaren A, Parsons M, Mouradov D, MacKinnon R, Catimel B, Liu S, et al. MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors. Cancer Discov. 2018;8:988-1005 pubmed publisher
Cai N, Lou L, Al Saadi N, Tetteh S, Runnels L. The kinase activity of the channel-kinase protein TRPM7 regulates stability and localization of the TRPM7 channel in polarized epithelial cells. J Biol Chem. 2018;293:11491-11504 pubmed publisher
Rousseaux M, Revelli J, Vázquez Vélez G, Kim J, Craigen E, Gonzales K, et al. Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau. elife. 2018;7: pubmed publisher
He L, Gomes A, Wang X, Yoon S, Lee G, Nagiec M, et al. mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation. Mol Cell. 2018;70:949-960.e4 pubmed publisher
Wang D, Mokhonova E, Kendall G, Becerra D, Naeini Y, Cantor R, et al. Repurposing Dantrolene for Long-Term Combination Therapy to Potentiate Antisense-Mediated DMD Exon Skipping in the mdx Mouse. Mol Ther Nucleic Acids. 2018;11:180-191 pubmed publisher
Cerquone Perpetuini A, Re Cecconi A, Chiappa M, Martinelli G, Fuoco C, Desiderio G, et al. Group I Paks support muscle regeneration and counteract cancer-associated muscle atrophy. J Cachexia Sarcopenia Muscle. 2018;9:727-746 pubmed publisher
Borck P, Batista T, Vettorazzi J, Soares G, Lubaczeuski C, Guan D, et al. Nighttime light exposure enhances Rev-erbα-targeting microRNAs and contributes to hepatic steatosis. Metabolism. 2018;85:250-258 pubmed publisher
van Nieuwenhove E, Garcia Perez J, Helsen C, Rodriguez P, van Schouwenburg P, Dooley J, et al. A kindred with Mutant IKAROS and autoimmunity. J Allergy Clin Immunol. 2018;: pubmed publisher
Haggerty A, Al Ali H, Oudega M. Soluble laminin polymers enhance axon growth of primary neurons in vitro. J Biomed Mater Res A. 2018;106:2372-2381 pubmed publisher
Zhang J, Dulak A, Hattersley M, Willis B, Nikkilä J, Wang A, et al. BRD4 facilitates replication stress-induced DNA damage response. Oncogene. 2018;37:3763-3777 pubmed publisher
Bildik G, Akin N, Senbabaoglu F, Esmalian Y, Sahin G, Urman D, et al. Endogenous c-Jun N-terminal kinase (JNK) activity marks the boundary between normal and malignant granulosa cells. Cell Death Dis. 2018;9:421 pubmed publisher
Hall C, Wells A, Leung K. Pirfenidone reduces profibrotic responses in human dermal myofibroblasts, in vitro. Lab Invest. 2018;98:640-655 pubmed publisher
Jin Y, Valenzuela N, Zhang X, Rozengurt E, Reed E. HLA Class II-Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection. J Immunol. 2018;200:2372-2390 pubmed publisher
Markussen L, Winther S, Wicksteed B, Hansen J. GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Sci Rep. 2018;8:3469 pubmed publisher
Heidelberger J, Voigt A, Borisova M, Petrosino G, Ruf S, Wagner S, et al. Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function. EMBO Rep. 2018;19: pubmed publisher
Kuragano M, Uyeda T, Kamijo K, Murakami Y, Takahashi M. Different contributions of nonmuscle myosin IIA and IIB to the organization of stress fiber subtypes in fibroblasts. Mol Biol Cell. 2018;: pubmed publisher
Robinson C, Lefebvre F, Poon B, Bousard A, Fan X, Lathrop M, et al. Consequences of VHL Loss on Global DNA Methylome. Sci Rep. 2018;8:3313 pubmed publisher
Böhler P, Stuhldreier F, Anand R, Kondadi A, Schlütermann D, Berleth N, et al. The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane. Cell Death Dis. 2018;9:286 pubmed publisher
Cervero P, Wiesner C, Bouissou A, Poincloux R, Linder S. Lymphocyte-specific protein 1 regulates mechanosensory oscillation of podosomes and actin isoform-based actomyosin symmetry breaking. Nat Commun. 2018;9:515 pubmed publisher
Monje P, Sant D, Wang G. Phenotypic and Functional Characteristics of Human Schwann Cells as Revealed by Cell-Based Assays and RNA-SEQ. Mol Neurobiol. 2018;55:6637-6660 pubmed publisher
Sulli G, Rommel A, Wang X, Kolar M, Puca F, Saghatelian A, et al. Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence. Nature. 2018;553:351-355 pubmed publisher
Chopra A, Kutys M, Zhang K, Polacheck W, Sheng C, Luu R, et al. Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions. Dev Cell. 2018;44:87-96.e5 pubmed publisher
Chen P, Muzumdar M, Dorans K, Robbins R, Bhutkar A, Del Rosario A, et al. Adaptive and Reversible Resistance to Kras Inhibition in Pancreatic Cancer Cells. Cancer Res. 2018;78:985-1002 pubmed publisher
Ushijima T, Fujimoto N, Matsuyama S, Kan O M, Kiyonari H, Shioi G, et al. The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice. J Biol Chem. 2018;293:148-162 pubmed publisher
Genna A, Lapetina S, Lukic N, Twafra S, Meirson T, Sharma V, et al. Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells. J Cell Biol. 2018;217:375-395 pubmed publisher
Dendo K, Yugawa T, Nakahara T, Ohno S, Goshima N, Arakawa H, et al. Induction of non-apoptotic programmed cell death by oncogenic RAS in human epithelial cells and its suppression by MYC overexpression. Carcinogenesis. 2018;39:202-213 pubmed publisher
Pryzhkova M, Harris G, Ma S, Jabbarzadeh E. Patterning Pluripotent Stem Cells at a Single Cell Level. J Biomater Tissue Eng. 2013;3:461-471 pubmed publisher
Vecera J, Kudová J, Kucera J, Kubala L, Pachernik J. Neural Differentiation Is Inhibited through HIF1α/β-Catenin Signaling in Embryoid Bodies. Stem Cells Int. 2017;2017:8715798 pubmed publisher
Chocry M, Leloup L, Kovacic H. Reversion of resistance to oxaliplatin by inhibition of p38 MAPK in colorectal cancer cell lines: involvement of the calpain / Nox1 pathway. Oncotarget. 2017;8:103710-103730 pubmed publisher
Nedjari S, Awaja F, Altankov G. Three Dimensional Honeycomb Patterned Fibrinogen Based Nanofibers Induce Substantial Osteogenic Response of Mesenchymal Stem Cells. Sci Rep. 2017;7:15947 pubmed publisher
Wozniak D, Kajdacsy Balla A, Macias V, Ball Kell S, Zenner M, Bie W, et al. PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer. Nat Commun. 2017;8:1508 pubmed publisher
Torregrosa Muñumer R, Forslund J, Goffart S, Pfeiffer A, Stojkovič G, Carvalho G, et al. PrimPol is required for replication reinitiation after mtDNA damage. Proc Natl Acad Sci U S A. 2017;114:11398-11403 pubmed publisher
Xiao Z, Han L, Lee H, Zhuang L, Zhang Y, Baddour J, et al. Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development. Nat Commun. 2017;8:783 pubmed publisher
Kyrychenko V, Kyrychenko S, Tiburcy M, Shelton J, Long C, Schneider J, et al. Functional correction of dystrophin actin binding domain mutations by genome editing. JCI Insight. 2017;2: pubmed publisher
Huet Calderwood C, Rivera Molina F, Iwamoto D, Kromann E, Toomre D, Calderwood D. Novel ecto-tagged integrins reveal their trafficking in live cells. Nat Commun. 2017;8:570 pubmed publisher
Goldstein J, Berger A, Shih J, Duke F, Furst L, Kwiatkowski D, et al. Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer. Cancer Res. 2017;77:6987-6998 pubmed publisher
Ichikawa T, Kita M, Matsui T, Nagasato A, Araki T, Chiang S, et al. Vinexin family (SORBS) proteins play different roles in stiffness-sensing and contractile force generation. J Cell Sci. 2017;130:3517-3531 pubmed publisher
Mukai M, Suruga N, Saeki N, Ogawa K. EphA receptors and ephrin-A ligands are upregulated by monocytic differentiation/maturation and promote cell adhesion and protrusion formation in HL60 monocytes. BMC Cell Biol. 2017;18:28 pubmed publisher
Liao W, Juo L, Shih Y, Chen Y, Yan Y. HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity. PLoS Genet. 2017;13:e1006984 pubmed publisher
Beneke A, Guentsch A, Hillemann A, Zieseniss A, Swain L, Katschinski D. Loss of PHD3 in myeloid cells dampens the inflammatory response and fibrosis after hind-limb ischemia. Cell Death Dis. 2017;8:e2976 pubmed publisher
Peterson J, Lin B, Shin J, Phelan P, Tsichlis P, Schwob J, et al. Replication of JC Virus DNA in the G144 Oligodendrocyte Cell Line Is Dependent Upon Akt. J Virol. 2017;91: pubmed publisher
Abagnale G, Sechi A, Steger M, Zhou Q, Kuo C, Aydin G, et al. Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies. Stem Cell Reports. 2017;9:654-666 pubmed publisher
Takito J, Otsuka H, Inoue S, Kawashima T, Nakamura M. Symmetrical retrograde actin flow in the actin fusion structure is involved in osteoclast fusion. Biol Open. 2017;6:1104-1114 pubmed publisher
Shutova M, Asokan S, Talwar S, Assoian R, Bear J, Svitkina T. Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility. J Cell Biol. 2017;216:2877-2889 pubmed publisher
Hoelzl M, Heby Henricson K, Gerling M, Dias J, Kuiper R, Trünkle C, et al. Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model. Dev Biol. 2017;429:132-146 pubmed publisher
Taskin M, Xia D, Besenbacher F, Dong M, Chen M. Nanotopography featured polycaprolactone/polyethyleneoxide microfibers modulate endothelial cell response. Nanoscale. 2017;9:9218-9229 pubmed publisher
Grumati P, Morozzi G, Hölper S, Mari M, Harwardt M, Yan R, et al. Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy. elife. 2017;6: pubmed publisher
Vessichelli M, Mariggio S, Varone A, Zizza P, Di Santo A, Amore C, et al. The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses. J Biol Chem. 2017;292:12828-12841 pubmed publisher
Hirata H, Samsonov M, Sokabe M. Actomyosin contractility provokes contact inhibition in E-cadherin-ligated keratinocytes. Sci Rep. 2017;7:46326 pubmed publisher
Mekhdjian A, Kai F, Rubashkin M, Prahl L, Przybyla L, McGregor A, et al. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Mol Biol Cell. 2017;28:1467-1488 pubmed publisher
Faust J, Christenson W, Doudrick K, Ros R, Ugarova T. Development of fusogenic glass surfaces that impart spatiotemporal control over macrophage fusion: Direct visualization of multinucleated giant cell formation. Biomaterials. 2017;128:160-171 pubmed publisher
Jacob A, Amack J, Turner C. Paxillin genes and actomyosin contractility regulate myotome morphogenesis in zebrafish. Dev Biol. 2017;425:70-84 pubmed publisher
Stutchbury B, Atherton P, Tsang R, Wang D, Ballestrem C. Distinct focal adhesion protein modules control different aspects of mechanotransduction. J Cell Sci. 2017;130:1612-1624 pubmed publisher
Giampietro C, Lionetti M, Costantini G, Mutti F, Zapperi S, La Porta C. Cholesterol impairment contributes to neuroserpin aggregation. Sci Rep. 2017;7:43669 pubmed publisher
Lin Y, Zhen Y, Chien K, Lee I, Lin W, Chen M, et al. LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration. Mol Biol Cell. 2017;28:1054-1065 pubmed publisher
Reynolds J, Bicknell L, Carroll P, Higgs M, Shaheen R, Murray J, et al. Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism. Nat Genet. 2017;49:537-549 pubmed publisher
Xue R, Zeng J, Chen Y, Chen C, Tan W, Zhao J, et al. Sestrin 1 ameliorates cardiac hypertrophy via autophagy activation. J Cell Mol Med. 2017;21:1193-1205 pubmed publisher
Chang Y, Huang Y. Midbody localization of vinexin recruits rhotekin to facilitate cytokinetic abscission. Cell Cycle. 2017;16:2046-2057 pubmed publisher
Lardelli R, Schaffer A, Eggens V, Zaki M, Grainger S, Sathe S, et al. Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet. 2017;49:457-464 pubmed publisher
Tonelli C, Morelli M, Sabò A, Verrecchia A, Rotta L, Capra T, et al. Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas. Oncogene. 2017;36:2921-2929 pubmed publisher
Delage E, Cervantes D, Pénard E, Schmitt C, Syan S, Disanza A, et al. Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes. Sci Rep. 2016;6:39632 pubmed publisher
Eggenschwiler R, Moslem M, Fráguas M, Galla M, Papp O, Naujock M, et al. Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase. Sci Rep. 2016;6:38198 pubmed publisher
Coly P, Perzo N, Le Joncour V, Lecointre C, Schouft M, Desrues L, et al. Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis. Autophagy. 2016;12:2344-2362 pubmed
Scherer S, Bauer J, Schmaus A, Neumaier C, Herskind C, Veldwijk M, et al. TGF-β1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT). PLoS ONE. 2016;11:e0162221 pubmed publisher
Krstic M, MacMillan C, Leong H, Clifford A, Souter L, Dales D, et al. The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer. BMC Cancer. 2016;16:671 pubmed publisher
Wang H, Vilela M, Winkler A, Tarnawski M, Schlichting I, Yumerefendi H, et al. LOVTRAP: an optogenetic system for photoinduced protein dissociation. Nat Methods. 2016;13:755-8 pubmed publisher
Feng X, Liu P, Zhou X, Li M, Li F, Wang Z, et al. Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration. J Biol Chem. 2016;291:18947-58 pubmed publisher
Ng I, Pawijit P, Teo L, Li H, Lee S, Yu H. Kinectin-dependent ER transport supports the focal complex maturation required for chemotaxis in shallow gradients. J Cell Sci. 2016;129:2660-72 pubmed publisher
Casado Medrano V, Barrio Real L, Garcia Rostan G, Baumann M, Rocks O, Caloca M. A new role of the Rac-GAP ?2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression. Oncotarget. 2016;7:28301-19 pubmed publisher
Chouchani E, Kazak L, Jedrychowski M, Lu G, Erickson B, Szpyt J, et al. Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature. 2016;532:112-6 pubmed publisher
Dooley J, Tian L, Schonefeldt S, Delghingaro Augusto V, Garcia Perez J, Pasciuto E, et al. Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes. Nat Genet. 2016;48:519-27 pubmed publisher
Janssens V, Zwaenepoel K, Rosse C, Petit M, Goris J, Parker P. PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration. J Cell Sci. 2016;129:1605-18 pubmed publisher
McGrath J, Williamson K, Balasubramanian S, Odate S, Arora S, Hatton C, et al. Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes. Cancer Res. 2016;76:1975-88 pubmed publisher
Horton E, Humphries J, Stutchbury B, Jacquemet G, Ballestrem C, Barry S, et al. Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. J Cell Biol. 2016;212:349-64 pubmed publisher
Mullarky E, Lucki N, Beheshti Zavareh R, Anglin J, Gomes A, Nicolay B, et al. Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers. Proc Natl Acad Sci U S A. 2016;113:1778-83 pubmed publisher
Minns M, Teicher G, Rich C, Trinkaus Randall V. Purinoreceptor P2X7 Regulation of Ca(2+) Mobilization and Cytoskeletal Rearrangement Is Required for Corneal Reepithelialization after Injury. Am J Pathol. 2016;186:285-96 pubmed publisher
Atherton P, Stutchbury B, Wang D, Jethwa D, Tsang R, Meiler Rodriguez E, et al. Vinculin controls talin engagement with the actomyosin machinery. Nat Commun. 2015;6:10038 pubmed publisher
Panzer L, Trübe L, Klose M, Joosten B, Slotman J, Cambi A, et al. The formins FHOD1 and INF2 regulate inter- and intra-structural contractility of podosomes. J Cell Sci. 2016;129:298-313 pubmed publisher
Labrousse Arias D, Castillo González R, Rogers N, Torres Capelli M, Barreira B, Aragonés J, et al. HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction. Cardiovasc Res. 2016;109:115-30 pubmed publisher
Horton E, Byron A, Askari J, Ng D, Millon Frémillon A, Robertson J, et al. Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly. Nat Cell Biol. 2015;17:1577-1587 pubmed publisher
Baker B, Trappmann B, Wang W, Sakar M, Kim I, Shenoy V, et al. Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments. Nat Mater. 2015;14:1262-8 pubmed publisher
Musílková J, Kotelnikov I, Novotná K, Pop Georgievski O, Rypacek F, Bacakova L, et al. Cell adhesion and growth enabled by biomimetic oligopeptide modification of a polydopamine-poly(ethylene oxide) protein repulsive surface. J Mater Sci Mater Med. 2015;26:253 pubmed publisher
Lagarrigue F, Vikas Anekal P, Lee H, Bachir A, Ablack J, Horwitz A, et al. A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. Nat Commun. 2015;6:8492 pubmed publisher
Tonelli C, Morelli M, Bianchi S, Rotta L, Capra T, Sabò A, et al. Genome-wide analysis of p53 transcriptional programs in B cells upon exposure to genotoxic stress in vivo. Oncotarget. 2015;6:24611-26 pubmed publisher
Karnezis A, Wang Y, Ramos P, Hendricks W, Oliva E, D Angelo E, et al. Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type. J Pathol. 2016;238:389-400 pubmed publisher
Murakawa Y, Hinz M, Mothes J, Schuetz A, Uhl M, Wyler E, et al. RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway. Nat Commun. 2015;6:7367 pubmed publisher
Newell Litwa K, Badoual M, Asmussen H, Patel H, Whitmore L, Horwitz A. ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity. J Cell Biol. 2015;210:225-42 pubmed publisher
Li R, Bourcy K, Wang T, Sun M, Kang Y. The involvement of vimentin in copper-induced regression of cardiomyocyte hypertrophy. Metallomics. 2015;7:1331-7 pubmed publisher
Ajeian J, Horton E, Astudillo P, Byron A, Askari J, Millon Frémillon A, et al. Proteomic analysis of integrin-associated complexes from mesenchymal stem cells. Proteomics Clin Appl. 2016;10:51-7 pubmed publisher
Hernández Varas P, Berge U, Lock J, Stromblad S. A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime. Nat Commun. 2015;6:7524 pubmed publisher
Schafer S, Adami E, Heinig M, Rodrigues K, Kreuchwig F, Silhavy J, et al. Translational regulation shapes the molecular landscape of complex disease phenotypes. Nat Commun. 2015;6:7200 pubmed publisher
Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y. The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation. PLoS ONE. 2015;10:e0124259 pubmed publisher
Jiang L, Kon N, Li T, Wang S, Su T, Hibshoosh H, et al. Ferroptosis as a p53-mediated activity during tumour suppression. Nature. 2015;520:57-62 pubmed publisher
Liu W, Su P, Gonzales A, Chen S, Wang N, Wang J, et al. Optimizing stem cell functions and antibacterial properties of TiO2 nanotubes incorporated with ZnO nanoparticles: experiments and modeling. Int J Nanomedicine. 2015;10:1997-2019 pubmed publisher
Schreiner B, Ingold Heppner B, Pehl D, Locatelli G, Berrit Schönthaler H, Becher B. Deletion of Jun proteins in adult oligodendrocytes does not perturb cell survival, or myelin maintenance in vivo. PLoS ONE. 2015;10:e0120454 pubmed publisher
Emmanuel M, Nakano Y, Nozaki T, Datta S. Small GTPase Rab21 mediates fibronectin induced actin reorganization in Entamoeba histolytica: implications in pathogen invasion. PLoS Pathog. 2015;11:e1004666 pubmed publisher
Byron A, Askari J, Humphries J, Jacquemet G, Koper E, Warwood S, et al. A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting. Nat Commun. 2015;6:6135 pubmed publisher
Smithline Z, Nikonova A, Hensley H, Cai K, Egleston B, Proia D, et al. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. PLoS ONE. 2014;9:e114403 pubmed publisher
Curado F, Spuul P, Egaña I, Rottiers P, Daubon T, Veillat V, et al. ALK5 and ALK1 play antagonistic roles in transforming growth factor β-induced podosome formation in aortic endothelial cells. Mol Cell Biol. 2014;34:4389-403 pubmed publisher
van der Ent W, Burrello C, Teunisse A, Ksander B, van der Velden P, Jager M, et al. Modeling of human uveal melanoma in zebrafish xenograft embryos. Invest Ophthalmol Vis Sci. 2014;55:6612-22 pubmed publisher
Holl E, Bond J, Selim M, Ehanire T, Sullenger B, Levinson H. The nucleic acid scavenger polyamidoamine third-generation dendrimer inhibits fibroblast activation and granulation tissue contraction. Plast Reconstr Surg. 2014;134:420e-33e pubmed publisher
Filova E, Suchy T, Sucharda Z, Supová M, Zaloudková M, Balík K, et al. Support for the initial attachment, growth and differentiation of MG-63 cells: a comparison between nano-size hydroxyapatite and micro-size hydroxyapatite in composites. Int J Nanomedicine. 2014;9:3687-706 pubmed publisher
Galletti M, Cantoni S, Zambelli F, Valente S, Palazzini M, Manes A, et al. Dissecting histone deacetylase role in pulmonary arterial smooth muscle cell proliferation and migration. Biochem Pharmacol. 2014;91:181-90 pubmed publisher
Sab A, Kress T, Pelizzola M, de Pretis S, Gorski M, Tesi A, et al. Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis. Nature. 2014;511:488-492 pubmed publisher
Brack S, Attinger Toller I, Schade B, Mourlane F, Klupsch K, Woods R, et al. A bispecific HER2-targeting FynomAb with superior antitumor activity and novel mode of action. Mol Cancer Ther. 2014;13:2030-9 pubmed publisher
van der Ent W, Jochemsen A, Teunisse A, Krens S, Szuhai K, Spaink H, et al. Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53. J Pathol. 2014;233:415-24 pubmed publisher
Jung K, Wu F, Wang P, Ye X, Abdulkarim B, Lai R. YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells. BMC Cancer. 2014;14:328 pubmed publisher
Bendris N, Cheung C, Leong H, Lewis J, Chambers A, Blanchard J, et al. Cyclin A2, a novel regulator of EMT. Cell Mol Life Sci. 2014;71:4881-94 pubmed publisher
Chorev D, Moscovitz O, Geiger B, Sharon M. Regulation of focal adhesion formation by a vinculin-Arp2/3 hybrid complex. Nat Commun. 2014;5:3758 pubmed publisher
Knight D, Gillies E, Mequanint K. Biomimetic L-aspartic acid-derived functional poly(ester amide)s for vascular tissue engineering. Acta Biomater. 2014;10:3484-96 pubmed publisher
Sarrazy V, Koehler A, Chow M, Zimina E, Li C, Kato H, et al. Integrins ?v?5 and ?v?3 promote latent TGF-?1 activation by human cardiac fibroblast contraction. Cardiovasc Res. 2014;102:407-17 pubmed publisher
Sabò A, Doni M, Amati B. SUMOylation of Myc-family proteins. PLoS ONE. 2014;9:e91072 pubmed publisher
Bernardo B, Gao X, Tham Y, Kiriazis H, Winbanks C, Ooi J, et al. Silencing of miR-34a attenuates cardiac dysfunction in a setting of moderate, but not severe, hypertrophic cardiomyopathy. PLoS ONE. 2014;9:e90337 pubmed publisher
Alvarez Quilón A, Serrano Benítez A, Lieberman J, Quintero C, Sánchez Gutiérrez D, Escudero L, et al. ATM specifically mediates repair of double-strand breaks with blocked DNA ends. Nat Commun. 2014;5:3347 pubmed publisher
Gurbuz I, Ferralli J, Roloff T, Chiquet Ehrismann R, Asparuhova M. SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients. Mol Cancer. 2014;13:22 pubmed publisher
Cui C, Chatterjee B, Lozito T, Zhang Z, Francis R, Yagi H, et al. Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol. 2013;11:e1001720 pubmed publisher
Yuan H, Russell R, Guan K. Regulation of PIK3C3/VPS34 complexes by MTOR in nutrient stress-induced autophagy. Autophagy. 2013;9:1983-95 pubmed
Lancaster M, Renner M, Martin C, Wenzel D, Bicknell L, Hurles M, et al. Cerebral organoids model human brain development and microcephaly. Nature. 2013;501:373-9 pubmed publisher
Vazquez Martin A, Cufí S, Oliveras Ferraros C, Torres Garcia V, Corominas Faja B, Cuyàs E, et al. IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations. Sci Rep. 2013;3:2560 pubmed publisher
Vogler M, Vogel S, Krull S, Farhat K, Leisering P, Lutz S, et al. Hypoxia modulates fibroblastic architecture, adhesion and migration: a role for HIF-1? in cofilin regulation and cytoplasmic actin distribution. PLoS ONE. 2013;8:e69128 pubmed publisher
Arnold T, Zang K, Vallejo Illarramendi A. Deletion of integrin-linked kinase from neural crest cells in mice results in aortic aneurysms and embryonic lethality. Dis Model Mech. 2013;6:1205-12 pubmed publisher
Russell R, Tian Y, Yuan H, Park H, Chang Y, Kim J, et al. ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat Cell Biol. 2013;15:741-50 pubmed publisher
Pellegrino L, Stebbing J, Braga V, Frampton A, Jacob J, Buluwela L, et al. miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts. Nucleic Acids Res. 2013;41:5400-12 pubmed publisher
Heir P, Sufan R, Greer S, Poon B, Lee J, Ohh M. DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase. Mol Cell Biol. 2013;33:1621-31 pubmed publisher
Sanchez Arévalo Lobo V, Doni M, Verrecchia A, Sanulli S, Fagà G, Piontini A, et al. Dual regulation of Myc by Abl. Oncogene. 2013;32:5261-71 pubmed publisher
Ng M, Besser A, Danuser G, Brugge J. Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility. J Cell Biol. 2012;199:545-63 pubmed publisher
Shi M, Pedchenko V, Greer B, Van Horn W, Santoro S, Sanders C, et al. Enhancing integrin ?1 inserted (I) domain affinity to ligand potentiates integrin ?1?1-mediated down-regulation of collagen synthesis. J Biol Chem. 2012;287:35139-52 pubmed publisher
Sandri C, Caccavari F, Valdembri D, Camillo C, Veltel S, Santambrogio M, et al. The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling. Cell Res. 2012;22:1479-501 pubmed publisher
Ho J, Metcalf J, Yan M, Turgeon P, Wang J, Chalsev M, et al. Functional importance of Dicer protein in the adaptive cellular response to hypoxia. J Biol Chem. 2012;287:29003-20 pubmed publisher
Cervero P, Himmel M, Kruger M, Linder S. Proteomic analysis of podosome fractions from macrophages reveals similarities to spreading initiation centres. Eur J Cell Biol. 2012;91:908-22 pubmed publisher
Bhuwania R, Cornfine S, Fang Z, Kruger M, Luna E, Linder S. Supervillin couples myosin-dependent contractility to podosomes and enables their turnover. J Cell Sci. 2012;125:2300-14 pubmed publisher
Juin A, Billottet C, Moreau V, Destaing O, Albiges Rizo C, Rosenbaum J, et al. Physiological type I collagen organization induces the formation of a novel class of linear invadosomes. Mol Biol Cell. 2012;23:297-309 pubmed publisher
Ben Khalifa Y, Teissier S, Tan M, Phan Q, Daynac M, Wong W, et al. The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63? upon transformation. PLoS Pathog. 2011;7:e1002256 pubmed publisher
Baranwal S, Wang Y, Rathinam R, Lee J, Jin L, McGoey R, et al. Molecular characterization of the tumor-suppressive function of nischarin in breast cancer. J Natl Cancer Inst. 2011;103:1513-28 pubmed publisher
Challa A, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011;31:3773-89 pubmed publisher
Hu S, Planus E, Georgess D, Place C, Wang X, Albiges Rizo C, et al. Podosome rings generate forces that drive saltatory osteoclast migration. Mol Biol Cell. 2011;22:3120-6 pubmed publisher
Grausova L, Kromka A, Burdikova Z, Eckhardt A, Rezek B, Vacik J, et al. Enhanced growth and osteogenic differentiation of human osteoblast-like cells on boron-doped nanocrystalline diamond thin films. PLoS ONE. 2011;6:e20943 pubmed publisher
Satelli A, Li S. Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell Mol Life Sci. 2011;68:3033-46 pubmed publisher
Hölscher M, Silter M, Krull S, von Ahlen M, Hesse A, Schwartz P, et al. Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury. J Biol Chem. 2011;286:11185-94 pubmed publisher
Akakura S, Nochajski P, Gao L, Sotomayor P, Matsui S, Gelman I. Rb-dependent cellular senescence, multinucleation and susceptibility to oncogenic transformation through PKC scaffolding by SSeCKS/AKAP12. Cell Cycle. 2010;9:4656-65 pubmed
Marg S, Winkler U, Sestu M, Himmel M, Schönherr M, Bär J, et al. The vinculin-DeltaIn20/21 mouse: characteristics of a constitutive, actin-binding deficient splice variant of vinculin. PLoS ONE. 2010;5:e11530 pubmed publisher
Toullec A, Gerald D, Despouy G, Bourachot B, Cardon M, Lefort S, et al. Oxidative stress promotes myofibroblast differentiation and tumour spreading. EMBO Mol Med. 2010;2:211-30 pubmed publisher
Kabuyama Y, Litman E, Templeton P, Metzner S, Witze E, Argast G, et al. A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme. Mol Cell Proteomics. 2009;8:2308-20 pubmed publisher
Mori M, Nakagami H, Koibuchi N, Miura K, Takami Y, Koriyama H, et al. Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis. Mol Biol Cell. 2009;20:3115-24 pubmed publisher
Lehmann M, Noack D, Wood M, Perego M, Knaus U. Lung epithelial injury by B. anthracis lethal toxin is caused by MKK-dependent loss of cytoskeletal integrity. PLoS ONE. 2009;4:e4755 pubmed publisher
Jin L, Hastings N, Blackman B, Somlyo A. Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury. J Muscle Res Cell Motil. 2009;30:41-55 pubmed publisher
Muller M, Bhattacharya S, Moore T, Prescott Q, Wedig T, Herrmann H, et al. Dominant cataract formation in association with a vimentin assembly disrupting mutation. Hum Mol Genet. 2009;18:1052-7 pubmed publisher
Cortesio C, Chan K, Perrin B, Burton N, Zhang S, Zhang Z, et al. Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion. J Cell Biol. 2008;180:957-71 pubmed publisher
Millon Fremillon A, Bouvard D, Grichine A, Manet Dupé S, Block M, Albiges Rizo C. Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity. J Cell Biol. 2008;180:427-41 pubmed publisher
Wipff P, Rifkin D, Meister J, Hinz B. Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J Cell Biol. 2007;179:1311-23 pubmed
Morita T, Mayanagi T, Sobue K. Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling. J Cell Biol. 2007;179:1027-42 pubmed
Shvartsman D, Donaldson J, Diaz B, Gutman O, Martin G, Henis Y. Src kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets. J Cell Biol. 2007;178:675-86 pubmed
Maddugoda M, Crampton M, Shewan A, Yap A. Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells. J Cell Biol. 2007;178:529-40 pubmed
Stöhr N, Lederer M, Reinke C, Meyer S, Hatzfeld M, Singer R, et al. ZBP1 regulates mRNA stability during cellular stress. J Cell Biol. 2006;175:527-34 pubmed
Ziegler W, Liddington R, Critchley D. The structure and regulation of vinculin. Trends Cell Biol. 2006;16:453-60 pubmed
Takizawa N, Smith T, Nebl T, Crowley J, Palmieri S, Lifshitz L, et al. Supervillin modulation of focal adhesions involving TRIP6/ZRP-1. J Cell Biol. 2006;174:447-58 pubmed
Pirone D, Liu W, Ruiz S, Gao L, Raghavan S, Lemmon C, et al. An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling. J Cell Biol. 2006;174:277-88 pubmed
Goffin J, Pittet P, Csucs G, Lussi J, Meister J, Hinz B. Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers. J Cell Biol. 2006;172:259-68 pubmed
Godsel L, Hsieh S, Amargo E, Bass A, Pascoe McGillicuddy L, Huen A, et al. Desmoplakin assembly dynamics in four dimensions: multiple phases differentially regulated by intermediate filaments and actin. J Cell Biol. 2005;171:1045-59 pubmed
Benlimame N, He Q, Jie S, Xiao D, Xu Y, Loignon M, et al. FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion. J Cell Biol. 2005;171:505-16 pubmed
Petit M, Crombez K, Vervenne H, Weyns N, Van de Ven W. The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins. FEBS Lett. 2005;579:5061-8 pubmed
Chen H, Cohen D, Choudhury D, Kioka N, Craig S. Spatial distribution and functional significance of activated vinculin in living cells. J Cell Biol. 2005;169:459-70 pubmed
Hyytiäinen M, Keski Oja J. Latent TGF-beta binding protein LTBP-2 decreases fibroblast adhesion to fibronectin. J Cell Biol. 2003;163:1363-74 pubmed
Davis M, Ireton R, Reynolds A. A core function for p120-catenin in cadherin turnover. J Cell Biol. 2003;163:525-34 pubmed
Mostafavi Pour Z, Askari J, Parkinson S, Parker P, Ng T, Humphries M. Integrin-specific signaling pathways controlling focal adhesion formation and cell migration. J Cell Biol. 2003;161:155-67 pubmed
Garvalov B, Higgins T, Sutherland J, Zettl M, Scaplehorn N, Kocher T, et al. The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions. J Cell Biol. 2003;161:33-9 pubmed
Klingbeil C, Hauck C, Hsia D, Jones K, Reider S, Schlaepfer D. Targeting Pyk2 to beta 1-integrin-containing focal contacts rescues fibronectin-stimulated signaling and haptotactic motility defects of focal adhesion kinase-null cells. J Cell Biol. 2001;152:97-110 pubmed
Bialkowska K, Kulkarni S, Du X, Goll D, Saido T, Fox J. Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active. J Cell Biol. 2000;151:685-96 pubmed
Krause M, Sechi A, Konradt M, Monner D, Gertler F, Wehland J. Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. J Cell Biol. 2000;149:181-94 pubmed
Schwartz E, Bizios R, Medow M, Gerritsen M. Exposure of human vascular endothelial cells to sustained hydrostatic pressure stimulates proliferation. Involvement of the alphaV integrins. Circ Res. 1999;84:315-22 pubmed
Cruz M, Dalgard C, Ignatius M. Functional partitioning of beta1 integrins revealed by activating and inhibitory mAbs. J Cell Sci. 1997;110 ( Pt 21):2647-59 pubmed
Brinck U, Mirzaie M, Korabiowska M, Meyer T. Expression rate of vinculin isoforms in human aortocoronary saphenous vein grafts. Int J Cardiol. 1997;59:125-32 pubmed
product information
Product No. :
V9264
Product Name :
Anti-Vinculin antibody, Mouse monoclonal
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
hVIN-1
Applications/Description :
Suitable for immunocytochemistry: 5-10 μg/mL using HS-68 human fibroblast cell culture; western blot: 0.05-0.1 μg/mL using HS-68 total cell extract; indirect ELISA; immunohistochemistry
Species Reactivity :
bovine, canine, mouse, rat, turkey, human, chicken, frog
Isotype :
IgG1
Concentration :
~1.0 mg/mL
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA