Published Application/Species/Sample/Dilution | Reference |
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- western blot; human; 1:3000; fig 5e
| Ma S, Mangala L, Hu W, Bayaktar E, Yokoi A, Hu W, et al. CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance. Cell Rep. 2021;36:109549 pubmed publisher
|
- western blot; mouse; fig s5d
| Hamm M, Sohier P, Petit V, Raymond J, Delmas V, Le Coz M, et al. BRN2 is a non-canonical melanoma tumor-suppressor. Nat Commun. 2021;12:3707 pubmed publisher
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- western blot; human; loading ...; fig 3a
| Leon K, Buj R, Lesko E, Dahl E, Chen C, Tangudu N, et al. DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A. J Cell Biol. 2021;220: pubmed publisher
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- immunocytochemistry; human; loading ...; fig 3c
| Shi X, Wen Z, Wang Y, Liu Y, Shi K, Jiu Y. Feedback-Driven Mechanisms Between Phosphorylated Caveolin-1 and Contractile Actin Assemblies Instruct Persistent Cell Migration. Front Cell Dev Biol. 2021;9:665919 pubmed publisher
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- western blot; human; 1:1000; fig 1a
| Huang J, Zhang Q, Shen J, Chen X, Ma S. Multi-omics analysis identifies potential mechanisms of AURKB in mediating poor outcome of lung adenocarcinoma. Aging (Albany NY). 2021;13:5946-5966 pubmed publisher
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- western blot; human; 1:1000; fig 1a
| Lasch A, Marx Stoelting P, Braeuning A, Lichtenstein D. More than additive effects on liver triglyceride accumulation by combinations of steatotic and non-steatotic pesticides in HepaRG cells. Arch Toxicol. 2021;95:1397-1411 pubmed publisher
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- western blot; human; 1:1000; fig 1a
| Buj R, Leon K, Anguelov M, Aird K. Suppression of p16 alleviates the senescence-associated secretory phenotype. Aging (Albany NY). 2021;13:3290-3312 pubmed publisher
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- immunocytochemistry; mouse; 1:400; loading ...; fig 1a
- immunocytochemistry; human; 1:400; loading ...; fig 1a
| Lehtimäki J, Rajakylä E, Tojkander S, Lappalainen P. Generation of stress fibers through myosin-driven reorganization of the actin cortex. elife. 2021;10: pubmed publisher
|
- western blot; mouse; 1:2000; loading ...; fig 1a
| Pavlova N, King B, Josselsohn R, Violante S, Macera V, Vardhana S, et al. Translation in amino-acid-poor environments is limited by tRNAGln charging. elife. 2020;9: pubmed publisher
|
- western blot; mouse; 1:5000; loading ...; fig s3-1b
| Crespo M, González Terán B, Nikolic I, Mora A, Folgueira C, Rodriguez E, et al. Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism. elife. 2020;9: pubmed publisher
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- western blot; mouse; 1:20,000; loading ...; fig 3b
| Terrey M, Adamson S, Gibson A, Deng T, Ishimura R, Chuang J, et al. GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis. elife. 2020;9: pubmed publisher
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- immunohistochemistry - frozen section; mouse; loading ...; fig s3
| Schuld J, Orfanos Z, Chevessier F, Eggers B, Heil L, Uszkoreit J, et al. Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation. Acta Neuropathol Commun. 2020;8:154 pubmed publisher
|
- western blot; human; fig 3d
| Barnat M, Capizzi M, Aparicio E, Boluda S, Wennagel D, Kacher R, et al. Huntington's disease alters human neurodevelopment. Science. 2020;369:787-793 pubmed publisher
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- western blot; human; 1:10,000; loading ...; fig 3b, 3e
| Thomsen E, Rovsing A, Anderson M, Due H, Huang J, Luo Y, et al. Identification of BLNK and BTK as mediators of rituximab-induced programmed cell death by CRISPR screens in GCB-subtype diffuse large B-cell lymphoma. Mol Oncol. 2020;: pubmed publisher
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- immunocytochemistry; mouse; 1:1000; loading ...; fig 7d
| Damiano Guercio J, Kurzawa L, Mueller J, Dimchev G, Schaks M, Nemethova M, et al. Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion. elife. 2020;9: pubmed publisher
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- immunocytochemistry; human; 1:400; loading ...
| D Souza R, Lim J, Turgut A, Servage K, Zhang J, Orth K, et al. Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex. elife. 2020;9: pubmed publisher
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- western blot; mouse; loading ...; fig 4c
| Atashpaz S, Samadi Shams S, Gonzalez J, Sebestyén E, Arghavanifard N, Gnocchi A, et al. ATR expands embryonic stem cell fate potential in response to replication stress. elife. 2020;9: pubmed publisher
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- western blot; mouse; loading ...; fig 3a
| Zhang Y, Li H, Min Y, Sanchez Ortiz E, Huang J, Mireault A, et al. Enhanced CRISPR-Cas9 correction of Duchenne muscular dystrophy in mice by a self-complementary AAV delivery system. Sci Adv. 2020;6:eaay6812 pubmed publisher
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- western blot; human; 1:500; loading ...
| Mukherjee A, Singh R, Udayan S, Biswas S, Reddy P, Manmadhan S, et al. A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells. elife. 2020;9: pubmed publisher
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- western blot; mouse; loading ...
| Goswami D, Chen D, Yang Y, Gudla P, Columbus J, Worthy K, et al. Membrane interactions of the globular domain and the hypervariable region of KRAS4b define its unique diffusion behavior. elife. 2020;9: pubmed publisher
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- western blot; human; loading ...; fig 1a
| Patel H, Tao N, Lee K, Huerta M, Arlt H, Mullarkey T, et al. Elacestrant (RAD1901) exhibits anti-tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors. Breast Cancer Res. 2019;21:146 pubmed publisher
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- western blot; human; 1:10,000; loading ...; fig 4d, 4f, e2a
| Ramírez C, Hauser A, Vucic E, Bar Sagi D. Plasma membrane V-ATPase controls oncogenic RAS-induced macropinocytosis. Nature. 2019;576:477-481 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 10a
| Luxan G, Stewen J, Díaz N, Kato K, Maney S, Aravamudhan A, et al. Endothelial EphB4 maintains vascular integrity and transport function in adult heart. elife. 2019;8: pubmed publisher
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- western blot; mouse; loading ...; fig s3d
| de Morrée A, Klein J, Gan Q, Farup J, Urtasun A, Kanugovi A, et al. Alternative polyadenylation of Pax3 controls muscle stem cell fate and muscle function. Science. 2019;366:734-738 pubmed publisher
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- western blot; human; 1:10,000; loading ...; fig s7a
| Perera O, Sobinoff A, Teber E, Harman A, Maritz M, Yang S, et al. Telomerase promotes formation of a telomere protective complex in cancer cells. Sci Adv. 2019;5:eaav4409 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 5s2b
| Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. elife. 2019;8: pubmed publisher
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- western blot; rat; 1:15,000; loading ...; fig 3e
| Presby D, Checkley L, Jackman M, Higgins J, Jones K, Giles E, et al. Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Am J Physiol Regul Integr Comp Physiol. 2019;317:R684-R695 pubmed publisher
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- immunocytochemistry; human; 1:400; loading ...; fig 5a
| Marcus J, Bejerano Sagie M, Patterson N, Bagchi S, Verkhusha V, Connolly D, et al. Septin 9 isoforms promote tumorigenesis in mammary epithelial cells by increasing migration and ECM degradation through metalloproteinase secretion at focal adhesions. Oncogene. 2019;38:5839-5859 pubmed publisher
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- western blot; human; loading ...; fig ex4a
| Parolia A, Cieslik M, Chu S, Xiao L, Ouchi T, Zhang Y, et al. Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer. Nature. 2019;: pubmed publisher
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- western blot; mouse; 1:2000; loading ...; fig 2c
| Chaves Pérez A, Yilmaz M, Perna C, de la Rosa S, Djouder N. URI is required to maintain intestinal architecture during ionizing radiation. Science. 2019;364: pubmed publisher
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- immunocytochemistry; human; 1:250; loading ...; fig 2b
| Bayer S, Grither W, Brenot A, Hwang P, Barcus C, Ernst M, et al. DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs. elife. 2019;8: pubmed publisher
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- western blot; human; loading ...; fig 1c
| Gregersen L, Mitter R, Ugalde A, Nojima T, Proudfoot N, Agami R, et al. SCAF4 and SCAF8, mRNA Anti-Terminator Proteins. Cell. 2019;: pubmed publisher
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- immunocytochemistry; mouse; 1:400; loading ...; fig 4a
| Kang H, Yang B, Zhang K, Pan Q, Yuan W, Li G, et al. Immunoregulation of macrophages by dynamic ligand presentation via ligand-cation coordination. Nat Commun. 2019;10:1696 pubmed publisher
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- western blot; mouse; fig 1c
| Baluapuri A, Hofstetter J, Dudvarski Stankovic N, Endres T, Bhandare P, Vos S, et al. MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation. Mol Cell. 2019;74:674-687.e11 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 7a
- western blot; human; 1:5000; loading ...; fig 6a
| Miller C, Lou H, Simpson C, van de Kooij B, Ha B, Fisher O, et al. Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output. PLoS Biol. 2019;17:e2006540 pubmed publisher
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- western blot; mouse; 1:10,000; loading ...; fig 4a
| Aranda S, Alcaine Colet A, Blanco E, Borras E, Caillot C, Sabidó E, et al. Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation. Sci Adv. 2019;5:eaav2448 pubmed publisher
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- western blot; mouse; 1:10,000; loading ...; fig 3a
| Kurelac I, Iommarini L, Vatrinet R, Amato L, De Luise M, Leone G, et al. Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. Nat Commun. 2019;10:903 pubmed publisher
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- immunocytochemistry; human; 1:200; loading ...; fig 4b
- western blot; human; loading ...; fig 4b
| Moro A, Driscoll T, Boraas L, Armero W, Kasper D, Baeyens N, et al. MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nat Cell Biol. 2019;21:348-358 pubmed publisher
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- western blot; human; 1:2500; loading ...; fig 1i
| Chun J, Zhang J, Wilkins M, Subramanian B, Riella C, Magraner J, et al. Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity. Proc Natl Acad Sci U S A. 2019;116:3712-3721 pubmed publisher
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- western blot; human; 1:1000; loading ...; fig 3b
| Martin V, Chiriaco C, Modica C, Acquadro A, Cortese M, Galimi F, et al. Met inhibition revokes IFNγ-induction of PD-1 ligands in MET-amplified tumours. Br J Cancer. 2019;120:527-536 pubmed publisher
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- western blot; mouse; loading ...; fig s22c
| Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L, et al. H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science. 2019;363:294-297 pubmed publisher
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- immunocytochemistry; human; loading ...; fig 3g
| Jiu Y, Kumari R, Fenix A, Schaible N, Liu X, Varjosalo M, et al. Myosin-18B Promotes the Assembly of Myosin II Stacks for Maturation of Contractile Actomyosin Bundles. Curr Biol. 2019;29:81-92.e5 pubmed publisher
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- western blot; human; loading ...; fig 2c
| Degen M, Wiederkehr A, La Scala G, Carmann C, Schnyder I, Katsaros C. Keratinocytes Isolated From Individual Cleft Lip/Palate Patients Display Variations in Their Differentiation Potential in vitro. Front Physiol. 2018;9:1703 pubmed publisher
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- western blot; human; loading ...; fig 2c, s3b, s4d, s12b
| Gerber T, Murawala P, Knapp D, Masselink W, Schuez M, Hermann S, et al. Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration. Science. 2018;362: pubmed publisher
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- western blot; dogs; 1:1000; loading ...; fig 2a
| Amoasii L, Hildyard J, Li H, Sanchez Ortiz E, Mireault A, Caballero D, et al. Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy. Science. 2018;362:86-91 pubmed publisher
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- western blot; mouse; loading ...; fig 3d
| Matesanz N, Nikolic I, Leiva M, Pulgarín Alfaro M, Santamans A, Bernardo E, et al. p38α blocks brown adipose tissue thermogenesis through p38δ inhibition. PLoS Biol. 2018;16:e2004455 pubmed publisher
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- western blot; human; loading ...; fig s2f
| Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al. SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science. 2018;360:800-805 pubmed publisher
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- immunocytochemistry; mouse; 1:200; loading ...; fig 4g
| Hoefert J, Bjerke G, Wang D, Yi R. The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis. J Cell Biol. 2018;217:2185-2204 pubmed publisher
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- immunocytochemistry; dogs; 1:2000; fig s2b
- immunocytochemistry; human; 1:2000; loading ...; fig 3a
| Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher
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- western blot; human; fig s3a
| Ong D, Hu B, Ho Y, Sauvé C, Bristow C, Wang Q, et al. PAF promotes stemness and radioresistance of glioma stem cells. Proc Natl Acad Sci U S A. 2017;114:E9086-E9095 pubmed publisher
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- immunocytochemistry; human; 1:700; loading ...; fig 3b
| Lehtimäki J, Fenix A, Kotila T, Balistreri G, Paavolainen L, Varjosalo M, et al. UNC-45a promotes myosin folding and stress fiber assembly. J Cell Biol. 2017;216:4053-4072 pubmed publisher
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- immunocytochemistry; dogs; loading ...; fig 5b
| Fredriksson Lidman K, Van Itallie C, Tietgens A, Anderson J. Sorbin and SH3 domain-containing protein 2 (SORBS2) is a component of the acto-myosin ring at the apical junctional complex in epithelial cells. PLoS ONE. 2017;12:e0185448 pubmed publisher
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- immunocytochemistry; human; 1:10,000; loading ...; fig 2d
- immunocytochemistry; mouse; loading ...; fig 2d
| Huet Calderwood C, Rivera Molina F, Iwamoto D, Kromann E, Toomre D, Calderwood D. Novel ecto-tagged integrins reveal their trafficking in live cells. Nat Commun. 2017;8:570 pubmed publisher
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- western blot; mouse; loading ...; fig 1a
| Yang Y, Yang S, Guo J, Cui Y, Tang B, Li X, et al. Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17. J Neurosci. 2017;37:9101-9115 pubmed publisher
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- immunocytochemistry; human; 1:400; loading ...; fig 2e
| Nardone G, Oliver De La Cruz J, Vrbsky J, Martini C, Pribyl J, Skladal P, et al. YAP regulates cell mechanics by controlling focal adhesion assembly. Nat Commun. 2017;8:15321 pubmed publisher
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- western blot; human; loading ...; fig 2f
| van Wijk S, Fricke F, Herhaus L, Gupta J, Hötte K, Pampaloni F, et al. Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-?B and restricts bacterial proliferation. Nat Microbiol. 2017;2:17066 pubmed publisher
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- western blot; human; 1:5000; loading ...; fig 5d
| Thamotharan S, Chu A, Kempf K, Janzen C, Grogan T, Elashoff D, et al. Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport. PLoS ONE. 2017;12:e0176493 pubmed publisher
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- western blot; mouse; 1:10,000; loading ...; fig 7c
| Olvedy M, Tisserand J, Luciani F, Boeckx B, Wouters J, Lopez S, et al. Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma. J Clin Invest. 2017;127:2310-2325 pubmed publisher
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- immunohistochemistry; human; loading ...; fig 4b
| Jeong S, Lim S, Schevzov G, Gunning P, Helfman D. Loss of Tpm4.1 leads to disruption of cell-cell adhesions and invasive behavior in breast epithelial cells via increased Rac1 signaling. Oncotarget. 2017;8:33544-33559 pubmed publisher
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- western blot; mouse; 1:1000; loading ...; fig 4a
| Umar S, Partow Navid R, Ruffenach G, Iorga A, Moazeni S, Eghbali M. Severe pulmonary hypertension in aging female apolipoprotein E-deficient mice is rescued by estrogen replacement therapy. Biol Sex Differ. 2017;8:9 pubmed publisher
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- western blot; human; 1:10,000; loading ...; fig 3c
| Amici D, Pinal Fernández I, Mázala D, Lloyd T, Corse A, Christopher Stine L, et al. Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositis. Acta Neuropathol Commun. 2017;5:24 pubmed publisher
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- immunocytochemistry; chicken; fig 1
| Boswell B, Korol A, West Mays J, Musil L. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell. 2017;28:907-921 pubmed publisher
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- western blot; rat; 1:3000; loading ...; fig 4c
| Dukic A, Haugen L, Pidoux G, Leithe E, Bakke O, Tasken K. A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells. Cell Signal. 2017;32:1-11 pubmed publisher
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- immunocytochemistry; human; 1:400; loading ...; fig 1b
| Rafiq N, Lieu Z, Jiang T, Yu C, Matsudaira P, Jones G, et al. Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO. J Cell Biol. 2017;216:181-197 pubmed publisher
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- western blot; human; 1:1000; fig s6a
| Eggenschwiler R, Moslem M, Fráguas M, Galla M, Papp O, Naujock M, et al. Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase. Sci Rep. 2016;6:38198 pubmed publisher
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- western blot; human; loading ...; fig 7a
| Amigo Jiménez I, Bailón E, Aguilera Montilla N, GarcÃa Marco J, GarcÃa Pardo A. Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9. Oncotarget. 2016;7:83359-83377 pubmed publisher
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- western blot; human; 1:250,000; loading ...; fig 2a
| Puschmann A, Fiesel F, Caulfield T, Hudec R, Ando M, Truban D, et al. Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism. Brain. 2017;140:98-117 pubmed publisher
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- western blot; mouse; 1:1000; fig 1g
| Beyer S, Pontis J, Schirwis E, Battisti V, Rudolf A, Le Grand F, et al. Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation. Cell Discov. 2016;2:16037 pubmed
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- immunocytochemistry; human; 1:400; fig 1a
| Cain S, Mularczyk E, Singh M, Massam Wu T, Kielty C. ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions. Sci Rep. 2016;6:35956 pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 1b
- western blot; mouse; loading ...; fig 1e
- western blot; human; loading ...; fig 9a
| Kishi T, Mayanagi T, Iwabuchi S, Akasaka T, Sobue K. Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity. Oncotarget. 2016;7:72113-72130 pubmed publisher
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- western blot; human; 1:5000; fig 5a
| King B, Boccalatte F, Moran Crusio K, Wolf E, Wang J, Kayembe C, et al. The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells. Nat Immunol. 2016;17:1312-1321 pubmed publisher
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- immunocytochemistry; mouse; loading ...; fig 7a
- immunocytochemistry; human; loading ...; fig 3e
| Binamé F, Bidaud Meynard A, Magnan L, Piquet L, Montibus B, Chabadel A, et al. Cancer-associated mutations in the protrusion-targeting region of p190RhoGAP impact tumor cell migration. J Cell Biol. 2016;214:859-73 pubmed publisher
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- western blot; mouse; loading ...; fig 4j
- western blot; human; loading ...; fig s4a
| Wang D, Kon N, Lasso G, Jiang L, Leng W, Zhu W, et al. Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode. Nature. 2016;538:118-122 pubmed publisher
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- immunohistochemistry - paraffin section; zebrafish ; 1:200; loading ...; fig 7c
| Cheng F, Miao L, Wu Q, Gong X, Xiong J, Zhang J. Vinculin b deficiency causes epicardial hyperplasia and coronary vessel disorganization in zebrafish. Development. 2016;143:3522-3531 pubmed
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- immunocytochemistry; human; loading ...; fig 2a
| Chien J, Tsen S, Chien C, Liu H, Tung C, Lin C. ?TAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells. Cell Death Discov. 2016;2:16006 pubmed publisher
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- immunocytochemistry; human; fig 1
| Fokkelman M, Balcıoğlu H, Klip J, Yan K, Verbeek F, Danen E, et al. Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour. Sci Rep. 2016;6:31707 pubmed publisher
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- immunocytochemistry; human; 1:500; fig 4d
| Ryskamp D, Frye A, Phuong T, Yarishkin O, Jo A, Xu Y, et al. TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye. Sci Rep. 2016;6:30583 pubmed publisher
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- western blot; human; fig 1
| Lorenzin F, Benary U, Baluapuri A, Walz S, Jung L, von Eyss B, et al. Different promoter affinities account for specificity in MYC-dependent gene regulation. elife. 2016;5: pubmed publisher
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- western blot; mouse; fig 1
- western blot; human; fig 1
| Cao J, Wu L, Zhang S, Lu M, Cheung W, Cai W, et al. An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting. Nucleic Acids Res. 2016;44:e149 pubmed
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- immunocytochemistry; human; 1:100; fig 1
| Dorland Y, Malinova T, van Stalborch A, Grieve A, van Geemen D, Jansen N, et al. The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions. Nat Commun. 2016;7:12210 pubmed publisher
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- immunocytochemistry; mouse; 1:400; loading ...; fig 4c
| Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher
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| Dejesus R, Moretti F, McAllister G, Wang Z, Bergman P, Liu S, et al. Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62. elife. 2016;5: pubmed publisher
|
- western blot; mouse; 1:5000; fig 4b
| Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann J, Manns M, et al. MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun. 2016;7:11916 pubmed publisher
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- western blot; human; fig 2a
| Kemper K, Krijgsman O, Kong X, Cornelissen Steijger P, Shahrabi A, Weeber F, et al. BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts. Cell Rep. 2016;16:263-277 pubmed publisher
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- immunocytochemistry; human; fig 1d
| Daubon T, Spuul P, Alonso F, Fremaux I, Genot E. VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells. J Cell Sci. 2016;129:2586-98 pubmed publisher
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- immunocytochemistry; human; 1:100; loading ...
| Cichon M, Moruzzi M, Shqau T, Miller E, Mehner C, Ethier S, et al. MYC Is a Crucial Mediator of TGF?-Induced Invasion in Basal Breast Cancer. Cancer Res. 2016;76:3520-30 pubmed publisher
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- immunocytochemistry; mouse; 1:400; fig 1B
| Chen L, DeWispelaere A, Dastvan F, Osborne W, Blechner C, Windhorst S, et al. Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity. PLoS ONE. 2016;11:e0155726 pubmed publisher
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- western blot; human; fig 5
| Geissler R, Simkin A, Floss D, Patel R, Fogarty E, Scheller J, et al. A widespread sequence-specific mRNA decay pathway mediated by hnRNPs A1 and A2/B1. Genes Dev. 2016;30:1070-85 pubmed publisher
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- immunocytochemistry; rat; loading ...; fig 2c
| Boateng L, Bennin D, de Oliveira S, Huttenlocher A. Mammalian Actin-binding Protein-1/Hip-55 Interacts with FHL2 and Negatively Regulates Cell Invasion. J Biol Chem. 2016;291:13987-98 pubmed publisher
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- immunocytochemistry; human; 1:400; loading ...; fig 4e
| Razafiarison T, Silvan U, Meier D, Snedeker J. Surface-Driven Collagen Self-Assembly Affects Early Osteogenic Stem Cell Signaling. Adv Healthc Mater. 2016;5:1481-92 pubmed publisher
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- immunocytochemistry; human; fig 5
- western blot; human; fig 5
| Senda Y, Murata Kamiya N, Hatakeyama M. C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility. Cancer Sci. 2016;107:972-80 pubmed publisher
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- western blot; mouse; 1:1000; fig 8
| Iwai Takekoshi L, Ramos A, Schaler A, Weinreb S, Blazeski R, Mason C. Retinal pigment epithelial integrity is compromised in the developing albino mouse retina. J Comp Neurol. 2016;524:3696-3716 pubmed publisher
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- western blot; human; 1:1000; fig s5
| Conway A, Van Nostrand E, Pratt G, Aigner S, Wilbert M, Sundararaman B, et al. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Rep. 2016;15:666-679 pubmed publisher
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- western blot; human; fig 3
| Kumar A, Jagadeeshan S, Subramanian A, Chidambaram S, Surabhi R, Singhal M, et al. Molecular Mechanism of Regulation of MTA1 Expression by Granulocyte Colony-stimulating Factor. J Biol Chem. 2016;291:12310-21 pubmed publisher
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- western blot; mouse; fig 4
| Garrel G, Racine C, L hôte D, Denoyelle C, Guigon C, di Clemente N, et al. Anti-Müllerian hormone: a new actor of sexual dimorphism in pituitary gonadotrope activity before puberty. Sci Rep. 2016;6:23790 pubmed publisher
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- western blot; human; 1:10,000; fig s4
| Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, et al. Melanoma addiction to the long non-coding RNA SAMMSON. Nature. 2016;531:518-22 pubmed publisher
|
- immunocytochemistry; human; loading ...; fig 2a
| Schaufler V, Czichos Medda H, Hirschfeld Warnecken V, Neubauer S, Rechenmacher F, Medda R, et al. Selective binding and lateral clustering of ?5?1 and ?v?3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly. Cell Adh Migr. 2016;10:505-515 pubmed
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- immunohistochemistry - frozen section; mouse; 1:1000; fig 5
| Panousopoulou E, Hobbs C, Mason I, Green J, Formstone C. Epiboly generates the epidermal basal monolayer and spreads the nascent mammalian skin to enclose the embryonic body. J Cell Sci. 2016;129:1915-27 pubmed publisher
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- immunocytochemistry; human; fig 1f
| Muhamed I, Wu J, Sehgal P, Kong X, Tajik A, Wang N, et al. E-cadherin-mediated force transduction signals regulate global cell mechanics. J Cell Sci. 2016;129:1843-54 pubmed publisher
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- western blot; human; 1:10,000; fig s1
| Hein J, Nilsson J. Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry. Nat Commun. 2016;7:10975 pubmed publisher
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- western blot; human; 1:5000; tbl 4
| Wollscheid H, Biancospino M, He F, Magistrati E, Molteni E, Lupia M, et al. Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain. Nat Struct Mol Biol. 2016;23:300-308 pubmed publisher
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- immunocytochemistry; rat; 1:250; loading ...; fig 7c
| Bengtsson E, Lindblom K, Tillgren V, Aspberg A. The leucine-rich repeat protein PRELP binds fibroblast cell-surface proteoglycans and enhances focal adhesion formation. Biochem J. 2016;473:1153-64 pubmed publisher
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- western blot; human; fig s3
| Wild T, Larsen M, Narita T, Schou J, Nilsson J, Choudhary C. The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity. Cell Rep. 2016;14:1829-40 pubmed publisher
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- western blot; human; 1:1000; fig s5
| Kenific C, Stehbens S, Goldsmith J, Leidal A, Faure N, Ye J, et al. NBR1 enables autophagy-dependent focal adhesion turnover. J Cell Biol. 2016;212:577-90 pubmed publisher
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- western blot; human; fig 2
| Baietti M, Simíček M, Abbasi Asbagh L, Radaelli E, Lievens S, Crowther J, et al. OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination. EMBO Mol Med. 2016;8:288-303 pubmed publisher
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- immunocytochemistry; human; fig 2
| Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed publisher
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- western blot; human; loading ...; fig 2d
| Haikala H, Klefström J, Eilers M, Wiese K. MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures. Cell Cycle. 2016;15:316-23 pubmed publisher
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- western blot; human; fig s4
| Cekan P, Hasegawa K, Pan Y, Tubman E, Odde D, Chen J, et al. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Mol Biol Cell. 2016;27:1346-57 pubmed publisher
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- western blot; mouse; loading ...; fig 3e
| Davidson S, Papagiannakopoulos T, Olenchock B, Heyman J, Keibler M, Luengo A, et al. Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer. Cell Metab. 2016;23:517-28 pubmed publisher
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- western blot; human; fig 1
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- immunocytochemistry; human; 1:400; fig 6
- western blot; human; 1:1000; fig 5
| Horton E, Humphries J, Stutchbury B, Jacquemet G, Ballestrem C, Barry S, et al. Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition. J Cell Biol. 2016;212:349-64 pubmed publisher
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- western blot; human; fig s6c
| Walter D, Hoffmann S, Komseli E, Rappsilber J, Gorgoulis V, Sørensen C. SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication. Nat Commun. 2016;7:10530 pubmed publisher
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| Iorga A, Li J, Sharma S, Umar S, Bopassa J, Nadadur R, et al. Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. J Am Heart Assoc. 2016;5: pubmed publisher
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- immunocytochemistry; fishes ; 1:800; loading ...; fig 3D
| Nakata T, Okimura C, Mizuno T, Iwadate Y. The Role of Stress Fibers in the Shape Determination Mechanism of Fish Keratocytes. Biophys J. 2016;110:481-492 pubmed publisher
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- western blot; mouse; 1:1000; tbl 1
| Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
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- western blot; human; fig 4
| Dave J, Abbey C, Duran C, Seo H, Johnson G, Bayless K. Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase. J Cell Sci. 2016;129:743-56 pubmed publisher
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- immunocytochemistry; mouse; fig 3
| Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, et al. A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development. J Biol Chem. 2016;291:5817-31 pubmed publisher
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- immunocytochemistry; moga; 1:800; loading ...; fig 3a
| Sonoda A, Okimura C, Iwadate Y. Shape and Area of Keratocytes Are Related to the Distribution and Magnitude of Their Traction Forces. Cell Struct Funct. 2016;41:33-43 pubmed publisher
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- western blot; human; fig 2c
| Vergani E, Di Guardo L, Dugo M, Rigoletto S, Tragni G, Ruggeri R, et al. Overcoming melanoma resistance to vemurafenib by targeting CCL2-induced miR-34a, miR-100 and miR-125b. Oncotarget. 2016;7:4428-41 pubmed publisher
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- immunocytochemistry; human; 1:50; loading ...; fig 1a
| Tojkander S, Gateva G, Husain A, Krishnan R, Lappalainen P. Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly. elife. 2015;4:e06126 pubmed publisher
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- western blot; human; fig 3
| Zhang C, Li X, Adelmant G, Dobbins J, Geisen C, Oser M, et al. Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21. Proc Natl Acad Sci U S A. 2015;112:15372-7 pubmed publisher
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- immunohistochemistry; human; 1:5000; loading ...; tbl 1
| Shah F, Berggren D, Holmlund T, Levring Jäghagen E, Stål P. Unique expression of cytoskeletal proteins in human soft palate muscles. J Anat. 2016;228:487-94 pubmed publisher
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- immunohistochemistry; mouse; 1:100; loading ...; tbl 2
| Schill E, Lake J, Tusheva O, Nagy N, Bery S, Foster L, et al. Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse. Dev Biol. 2016;409:473-88 pubmed publisher
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- western blot; mouse; fig s1
- western blot; human; fig 3
| Hu X, Garcia C, Fazli L, Gleave M, Vitek M, Jansen M, et al. Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis. Sci Rep. 2015;5:15182 pubmed publisher
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- immunocytochemistry; human; 1:200; loading ...; fig s3d
| Doyle A, Carvajal N, Jin A, Matsumoto K, Yamada K. Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions. Nat Commun. 2015;6:8720 pubmed publisher
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- western blot; human; fig 6
| Amigo Jiménez I, Bailón E, Aguilera Montilla N, Terol M, GarcÃa Marco J, GarcÃa Pardo A. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways. Oncotarget. 2015;6:44832-48 pubmed publisher
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- western blot; mouse; fig 5
| Nikonova A, Deneka A, Eckman L, Kopp M, Hensley H, Egleston B, et al. Opposing Effects of Inhibitors of Aurora-A and EGFR in Autosomal-Dominant Polycystic Kidney Disease. Front Oncol. 2015;5:228 pubmed publisher
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- immunocytochemistry; human; 1:200; fig 4
- western blot; human; 1:4000; fig s3
| Austen K, Ringer P, Mehlich A, Chrostek Grashoff A, Kluger C, Klingner C, et al. Extracellular rigidity sensing by talin isoform-specific mechanical linkages. Nat Cell Biol. 2015;17:1597-606 pubmed publisher
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- immunocytochemistry; human; 1:400; fig 6
| Osmanagic Myers S, Rus S, Wolfram M, Brunner D, Goldmann W, Bonakdar N, et al. Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks. J Cell Sci. 2015;128:4138-50 pubmed publisher
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- western blot; human; fig 5
| Fuchs M, Luthold C, Guilbert S, Varlet A, Lambert H, Jetté A, et al. A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis. PLoS Genet. 2015;11:e1005582 pubmed publisher
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- immunocytochemistry; human; 1:400; fig 5
| Horton E, Byron A, Askari J, Ng D, Millon Frémillon A, Robertson J, et al. Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly. Nat Cell Biol. 2015;17:1577-1587 pubmed publisher
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- western blot; human; 1:5000; fig 4
| Meng Z, Moroishi T, Mottier Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed publisher
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- western blot; human; fig 4
| Castella M, Jacquemont C, Thompson E, Yeo J, Cheung R, Huang J, et al. FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2. PLoS Genet. 2015;11:e1005563 pubmed publisher
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- western blot; human; 1:10,000; fig 3a
| Setti M, Osti D, Richichi C, Ortensi B, Del Bene M, Fornasari L, et al. Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth. Oncotarget. 2015;6:31413-27 pubmed publisher
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- western blot; human; fig 4
| Doldi V, Callari M, Giannoni E, D Aiuto F, Maffezzini M, Valdagni R, et al. Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation. Oncotarget. 2015;6:31441-60 pubmed publisher
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- western blot; mouse; fig 3
| Park E, Kim N, Ficarro S, Zhang Y, Lee B, Cho A, et al. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat Struct Mol Biol. 2015;22:703-711 pubmed publisher
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- western blot; rat; 1:5000
| Chichger H, Braza J, Duong H, Stark M, Harrington E. Neovascularization in the pulmonary endothelium is regulated by the endosome: Rab4-mediated trafficking and p18-dependent signaling. Am J Physiol Lung Cell Mol Physiol. 2015;309:L700-9 pubmed publisher
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- western blot; mouse; 1:2000
| González Loyola A, Fernández Miranda G, Trakala M, Partida D, Samejima K, Ogawa H, et al. Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development. Mol Cell Biol. 2015;35:3566-78 pubmed publisher
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- immunocytochemistry; hamsters; 1:500; fig 10
| Newell Litwa K, Badoual M, Asmussen H, Patel H, Whitmore L, Horwitz A. ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity. J Cell Biol. 2015;210:225-42 pubmed publisher
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- western blot; human; 1:1000; fig 2
| Haraguchi M, Sato M, Ozawa M. CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells. PLoS ONE. 2015;10:e0132260 pubmed publisher
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| Lachmann N, Brennig S, Hillje R, Schermeier H, Phaltane R, Dahlmann J, et al. Tightly regulated 'all-in-one' lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy. Gene Ther. 2015;22:883-92 pubmed publisher
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- immunocytochemistry; mouse; fig 2
- western blot; mouse; fig 1
| Cáceres M, Ortiz L, Recabarren T, Romero A, Colombo A, Leiva Salcedo E, et al. TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility. PLoS ONE. 2015;10:e0130540 pubmed publisher
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- western blot; domestic sheep; 1:5000
| Girard M, Dohme Meier F, Silacci P, Ampuero Kragten S, Kreuzer M, Bee G. Forage legumes rich in condensed tannins may increase n-3 fatty acid levels and sensory quality of lamb meat. J Sci Food Agric. 2016;96:1923-33 pubmed publisher
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- immunocytochemistry; human; fig 4
| Poulter N, Pollitt A, Davies A, Malinova D, Nash G, Hannon M, et al. Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2/3 complex. Nat Commun. 2015;6:7254 pubmed publisher
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- immunocytochemistry; human
| Koh L, Ng B, Bertrand J, Thierry F. Transcriptional control of late differentiation in human keratinocytes by TAp63 and Notch. Exp Dermatol. 2015;24:754-60 pubmed publisher
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- western blot; human; fig 2
| Alonso Curbelo D, Osterloh L, Cañón E, Calvo T, MartÃnez Herranz R, Karras P, et al. RAB7 counteracts PI3K-driven macropinocytosis activated at early stages of melanoma development. Oncotarget. 2015;6:11848-62 pubmed
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- western blot; human; 1:150000
| Kiss A, Gong X, Kowalewski J, Shafqat Abbasi H, Strömblad S, Lock J. Non-monotonic cellular responses to heterogeneity in talin protein expression-level. Integr Biol (Camb). 2015;7:1171-85 pubmed publisher
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- western blot; bovine
- western blot; dogs
| Izawa G, Kobayashi W, Haraguchi M, Sudo A, Ozawa M. The ectopic expression of Snail in MDBK cells does not induce epithelial-mesenchymal transition. Int J Mol Med. 2015;36:166-72 pubmed publisher
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- immunocytochemistry; human; 1:100
| Lavenus S, Poxson D, Ogievetsky N, Dordick J, Siegel R. Stem cell behavior on tailored porous oxide surface coatings. Biomaterials. 2015;55:96-109 pubmed publisher
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- western blot; human; fig 1
| Isogai T, van der Kammen R, Innocenti M. SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton. Sci Rep. 2015;5:9802 pubmed publisher
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- western blot; mouse; 1:1000; fig 4
| Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, et al. Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice. Nat Commun. 2015;6:7035 pubmed publisher
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- immunocytochemistry; human; 1:100
| Pendegrass C, Lancashire H, Fontaine C, Chan G, Hosseini P, Blunn G. Intraosseous transcutaneous amputation prostheses versus dental implants: a comparison between keratinocyte and gingival epithelial cell adhesion in vitro. Eur Cell Mater. 2015;29:237-49 pubmed
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- western blot; mouse; 1:10,000; fig 6
| Laurent A, Calabrese M, Warnatz H, Yaspo M, Tkachuk V, Torres M, et al. ChIP-Seq and RNA-Seq analyses identify components of the Wnt and Fgf signaling pathways as Prep1 target genes in mouse embryonic stem cells. PLoS ONE. 2015;10:e0122518 pubmed publisher
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- western blot; hamsters; 1:1000; fig 2
| Grav L, Lee J, Gerling S, Kallehauge T, Hansen A, Kol S, et al. One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment. Biotechnol J. 2015;10:1446-56 pubmed publisher
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- immunocytochemistry; human
| Fukumoto M, Kurisu S, Yamada T, Takenawa T. α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation. PLoS ONE. 2015;10:e0120616 pubmed publisher
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- immunocytochemistry; human
| Mulens Arias V, Rojas J, Pérez Yagüe S, Morales M, Barber D. Polyethylenimine-coated SPIONs trigger macrophage activation through TLR-4 signaling and ROS production and modulate podosome dynamics. Biomaterials. 2015;52:494-506 pubmed publisher
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- western blot; human; 1:15,000; fig 3c
| Freischmidt A, Wieland T, Richter B, Ruf W, Schaeffer V, Müller K, et al. Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat Neurosci. 2015;18:631-6 pubmed publisher
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- immunocytochemistry; human; fig s5
| Le A, Huang Y, Pingle S, Kesari S, Wang H, Yong R, et al. Plexin-B2 promotes invasive growth of malignant glioma. Oncotarget. 2015;6:7293-304 pubmed
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- western blot; human; fig 6
| Wilson F, Johannessen C, Piccioni F, Tamayo P, Kim J, Van Allen E, et al. A functional landscape of resistance to ALK inhibition in lung cancer. Cancer Cell. 2015;27:397-408 pubmed publisher
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- western blot; human; 1:2000; fig s5
| Mo J, Meng Z, Kim Y, Park H, Hansen C, Kim S, et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat Cell Biol. 2015;17:500-10 pubmed publisher
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| Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed publisher
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- western blot; mouse; loading ...; fig s3a
| Woo J, Zhao X, Khan H, Penn C, Wang X, Joly Amado A, et al. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ. 2015;22:921-34 pubmed publisher
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- immunohistochemistry - frozen section; mouse; loading ...; fig 3
| Gravez B, Tarjus A, Pelloux V, Ouvrard Pascaud A, Delcayre C, Samuel J, et al. Aldosterone promotes cardiac endothelial cell proliferation in vivo. J Am Heart Assoc. 2015;4:e001266 pubmed publisher
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| Ehret F, Vogler S, Pojar S, Elliott D, Bradke F, Steiner B, et al. Mouse model of CADASIL reveals novel insights into Notch3 function in adult hippocampal neurogenesis. Neurobiol Dis. 2015;75:131-41 pubmed publisher
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- western blot; human; 1:50000
| Chiba T, Sakurada T, Watanabe R, Yamaguchi K, Kimura Y, Kioka N, et al. Fomiroid A, a novel compound from the mushroom Fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe. PLoS ONE. 2014;9:e116162 pubmed publisher
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- western blot; mouse; 1:1000; fig 4
| Wurm S, Zhang J, Guinea Viniegra J, GarcÃa F, Muñoz J, Bakiri L, et al. Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. Genes Dev. 2015;29:144-56 pubmed publisher
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| Ng D, Humphries J, Byron A, Millon Frémillon A, Humphries M. Microtubule-dependent modulation of adhesion complex composition. PLoS ONE. 2014;9:e115213 pubmed publisher
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- western blot; mouse; 1:10000
| Kalwa H, Storch U, Demleitner J, Fiedler S, Mayer T, Kannler M, et al. Phospholipase C epsilon (PLCε) induced TRPC6 activation: a common but redundant mechanism in primary podocytes. J Cell Physiol. 2015;230:1389-99 pubmed publisher
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| Smithline Z, Nikonova A, Hensley H, Cai K, Egleston B, Proia D, et al. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. PLoS ONE. 2014;9:e114403 pubmed publisher
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| Petti C, Picco G, Martelli M, Trisolini E, Bucci E, Perera T, et al. Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells. Oncotarget. 2015;6:221-33 pubmed
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- immunocytochemistry; mouse
| Elloumi Hannachi I, GarcÃa J, Shekeran A, GarcÃa A. Contributions of the integrin β1 tail to cell adhesive forces. Exp Cell Res. 2015;332:212-22 pubmed publisher
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| Sazonova O, Isenberg B, Herrmann J, Lee K, Purwada A, Valentine A, et al. Extracellular matrix presentation modulates vascular smooth muscle cell mechanotransduction. Matrix Biol. 2015;41:36-43 pubmed publisher
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- western blot; human; fig 3
| Katt W, Antonyak M, Cerione R. Simultaneously targeting tissue transglutaminase and kidney type glutaminase sensitizes cancer cells to acid toxicity and offers new opportunities for therapeutic intervention. Mol Pharm. 2015;12:46-55 pubmed publisher
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- immunocytochemistry; human
| Chen Y, Su P, Chen Y, Wei M, Huang C, Osterday K, et al. The effect of enterohemorrhagic E. coli infection on the cell mechanics of host cells. PLoS ONE. 2014;9:e112137 pubmed publisher
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- western blot; human; fig 5
| Qin J, Rajaratnam R, Feng L, Salami J, Barber Rotenberg J, Domsic J, et al. Development of organometallic S6K1 inhibitors. J Med Chem. 2015;58:305-14 pubmed publisher
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| Wanichawan P, Hafver T, Hodne K, Aronsen J, Lunde I, Dalhus B, et al. Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure. J Biol Chem. 2014;289:33984-98 pubmed publisher
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| Raman N, Nayak A, Muller S. mTOR signaling regulates nucleolar targeting of the SUMO-specific isopeptidase SENP3. Mol Cell Biol. 2014;34:4474-84 pubmed publisher
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- immunocytochemistry; African green monkey
| Ali M, Chuang C, Saif M. Reprogramming cellular phenotype by soft collagen gels. Soft Matter. 2014;10:8829-37 pubmed publisher
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- immunocytochemistry; human
| Rubashkin M, Cassereau L, Bainer R, DuFort C, Yui Y, Ou G, et al. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014;74:4597-611 pubmed publisher
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- immunocytochemistry; mouse; 1:400
| Monge C, Saha N, Boudou T, P zos V squez C, Dulong V, Glinel K, et al. Rigidity-patterned polyelectrolyte films to control myoblast cell adhesion and spatial organization. Adv Funct Mater. 2013;23:3432-3442 pubmed publisher
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- western blot; human; fig 1
| Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed publisher
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- immunohistochemistry; human; 1:100
| Le Provost G, Pullar C. ?2-adrenoceptor activation modulates skin wound healing processes to reduce scarring. J Invest Dermatol. 2015;135:279-88 pubmed publisher
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| Martin V, Corso S, Comoglio P, Giordano S. Increase of MET gene copy number confers resistance to a monovalent MET antibody and establishes drug dependence. Mol Oncol. 2014;8:1561-74 pubmed publisher
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- western blot; rat; 1:10000
| Cain S, Tyson J, Jones K, Snutch T. Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy. Pflugers Arch. 2015;467:1367-82 pubmed publisher
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- western blot; mouse; fig 3
| Meijer D, Sun Y, Liu T, Kane M, Alberta J, Adelmant G, et al. An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells. J Neurosci. 2014;34:8507-18 pubmed publisher
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- immunocytochemistry; human; 1:700; fig 3
| Dolega M, Wagh J, Gerbaud S, Kermarrec F, Alcaraz J, Martin D, et al. Facile bench-top fabrication of enclosed circular microchannels provides 3D confined structure for growth of prostate epithelial cells. PLoS ONE. 2014;9:e99416 pubmed publisher
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- western blot; human; 1:100000; fig 6
| Fiesel F, Moussaud Lamodière E, Ando M, Springer W. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci. 2014;127:3488-504 pubmed publisher
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| Zou M, Cao J, Liu Z, Huh S, Polyak K, Yan Q. Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes. J Biol Chem. 2014;289:17620-33 pubmed publisher
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- immunocytochemistry; mouse
- western blot; mouse
| Boudoukha S, Rivera Vargas T, Dang I, Kropp J, Cuvellier S, Gautreau A, et al. MiRNA let-7g regulates skeletal myoblast motility via Pinch-2. FEBS Lett. 2014;588:1623-9 pubmed publisher
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- immunocytochemistry; human
| Chlupác J, Filova E, Havlíkova J, Matejka R, Riedel T, Houska M, et al. The gene expression of human endothelial cells is modulated by subendothelial extracellular matrix proteins: short-term response to laminar shear stress. Tissue Eng Part A. 2014;20:2253-64 pubmed publisher
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| Ryszawy D, Sarna M, Rak M, Szpak K, Kedracka Krok S, Michalik M, et al. Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer. Carcinogenesis. 2014;35:1920-30 pubmed publisher
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- immunohistochemistry - frozen section; mouse; fig 6
- immunoprecipitation; mouse; fig 5, 7
- western blot; mouse; fig 5, 7
| Zemljic Harpf A, Godoy J, Platoshyn O, Asfaw E, Busija A, Domenighetti A, et al. Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes. J Cell Sci. 2014;127:1104-16 pubmed publisher
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| Yogev O, Williams V, Hinits Y, Hughes S. eIF4EBP3L acts as a gatekeeper of TORC1 in activity-dependent muscle growth by specifically regulating Mef2ca translational initiation. PLoS Biol. 2013;11:e1001679 pubmed publisher
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- immunocytochemistry; human
| Dave J, Kang H, Abbey C, Maxwell S, Bayless K. Proteomic profiling of endothelial invasion revealed receptor for activated C kinase 1 (RACK1) complexed with vimentin to regulate focal adhesion kinase (FAK). J Biol Chem. 2013;288:30720-33 pubmed publisher
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| Pavlova N, Pallasch C, Elia A, Braun C, Westbrook T, Hemann M, et al. A role for PVRL4-driven cell-cell interactions in tumorigenesis. elife. 2013;2:e00358 pubmed publisher
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- immunocytochemistry; human
| Ho Y, Kok S, Wang J, Lin L. Translucent titanium coating altered the composition of focal adhesions and promoted migration of osteoblast-like MG-63 cells on glass. J Biomed Mater Res A. 2014;102:1187-201 pubmed publisher
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