This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Vascular Endothelial Growth Factor human
catalog :
V7259
citations: 91
Reference
Lopes Coelho F, Silva F, Gouveia Fernandes S, Martins C, Lopes N, Domingues G, et al. Monocytes as Endothelial Progenitor Cells (EPCs), Another Brick in the Wall to Disentangle Tumor Angiogenesis. Cells. 2020;9: pubmed publisher
Tancharoen W, Aungsuchawan S, Pothacharoen P, Bumroongkit K, Puaninta C, Pangjaidee N, et al. Human platelet lysate as an alternative to fetal bovine serum for culture and endothelial differentiation of human amniotic fluid mesenchymal stem cells. Mol Med Rep. 2019;19:5123-5132 pubmed publisher
Ou K, Mertsch S, Theodoropoulou S, Wu J, Liu J, Copland D, et al. Restoring retinal neurovascular health via substance P. Exp Cell Res. 2019;380:115-123 pubmed publisher
Mao W, Peters H, Sutton M, Orozco A, Pang L, Yang H, et al. The role of vascular endothelial growth factor, interleukin 8, and insulinlike growth factor in sustaining autophagic DIRAS3-induced dormant ovarian cancer xenografts. Cancer. 2019;125:1267-1280 pubmed publisher
Esposito E, Hayakawa K, Ahn B, Chan S, Xing C, Liang A, et al. Effects of ischemic post-conditioning on neuronal VEGF regulation and microglial polarization in a rat model of focal cerebral ischemia. J Neurochem. 2018;146:160-172 pubmed publisher
Liu A, Sun J, Shi Y, Sun G, Zhang H. Effect of shRNA-mediated knockdown of vascular endothelial growth factor on the proliferation of choroid-retinal endothelial cells under hypoxic conditions. Exp Ther Med. 2015;10:1019-1024 pubmed
Matsuo T, Masumoto H, Tajima S, Ikuno T, Katayama S, Minakata K, et al. Efficient long-term survival of cell grafts after myocardial infarction with thick viable cardiac tissue entirely from pluripotent stem cells. Sci Rep. 2015;5:16842 pubmed publisher
Herkenne S, Paques C, Nivelles O, Lion M, Bajou K, Pollenus T, et al. The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis. Sci Signal. 2015;8:ra117 pubmed publisher
Gasparian M, Bychkov M, Yagolovich A, Dolgikh D, Kirpichnikov M. Mutations Enhancing Selectivity of Antitumor Cytokine TRAIL to DR5 Receptor Increase Its Cytotoxicity against Tumor Cells. Biochemistry (Mosc). 2015;80:1080-91 pubmed publisher
Schiavo A, Franzin C, Albiero M, Piccoli M, Spiro G, Bertin E, et al. Endothelial properties of third-trimester amniotic fluid stem cells cultured in hypoxia. Stem Cell Res Ther. 2015;6:209 pubmed publisher
Maloney J, Gao L. Proinflammatory Cytokines Increase Vascular Endothelial Growth Factor Expression in Alveolar Epithelial Cells. Mediators Inflamm. 2015;2015:387842 pubmed publisher
Grotz T, Jakub J, Mansfield A, Goldenstein R, Enninga E, Nevala W, et al. Evidence of Th2 polarization of the sentinel lymph node (SLN) in melanoma. Oncoimmunology. 2015;4:e1026504 pubmed
Panagopoulos V, Zinonos I, Leach D, Hay S, Liapis V, Zysk A, et al. Uncovering a new role for peroxidase enzymes as drivers of angiogenesis. Int J Biochem Cell Biol. 2015;68:128-38 pubmed publisher
Ding Q, Tian X, Li Y, Wang Q, Zhang C. Carvedilol may attenuate liver cirrhosis by inhibiting angiogenesis through the VEGF-Src-ERK signaling pathway. World J Gastroenterol. 2015;21:9566-76 pubmed publisher
Barthes J, Vrana N, Özçelik H, Gahoual R, François Y, Bacharouche J, et al. Priming cells for their final destination: microenvironment controlled cell culture by a modular ECM-mimicking feeder film. Biomater Sci. 2015;3:1302-11 pubmed publisher
Li Y, Fu S, Wang L, Wang F, Wang N, Cao Q, et al. Copper improves the anti-angiogenic activity of disulfiram through the EGFR/Src/VEGF pathway in gliomas. Cancer Lett. 2015;369:86-96 pubmed publisher
Fu Z, Chen X, Guan S, Yan Y, Lin H, Hua Z. Curcumin inhibits angiogenesis and improves defective hematopoiesis induced by tumor-derived VEGF in tumor model through modulating VEGF-VEGFR2 signaling pathway. Oncotarget. 2015;6:19469-82 pubmed
Heidari Hamedani G, Vivès R, Seffouh A, Afratis N, Oosterhof A, van Kuppevelt T, et al. Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma. Cell Signal. 2015;27:2054-67 pubmed publisher
Yu Q, Guo W, Cheng L, Lu Y, Shen J, Li P. Glucocorticoids Significantly Influence the Transcriptome of Bone Microvascular Endothelial Cells of Human Femoral Head. Chin Med J (Engl). 2015;128:1956-63 pubmed publisher
Chaki S, Barhoumi R, Rivera G. Actin remodeling by Nck regulates endothelial lumen formation. Mol Biol Cell. 2015;26:3047-60 pubmed publisher
Park J, Kim D, Kim Y, Lee I, Kwon Y. Endothelial Snail Regulates Capillary Branching Morphogenesis via Vascular Endothelial Growth Factor Receptor 3 Expression. PLoS Genet. 2015;11:e1005324 pubmed publisher
Schlich R, Lamers D, Eckel J, Sell H. Adipokines enhance oleic acid-induced proliferation of vascular smooth muscle cells by inducing CD36 expression. Arch Physiol Biochem. 2015;121:81-7 pubmed publisher
Ikhapoh I, Pelham C, Agrawal D. Atherogenic Cytokines Regulate VEGF-A-Induced Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells into Endothelial Cells. Stem Cells Int. 2015;2015:498328 pubmed publisher
Xu J, Yi Y, Li L, Zhang W, Wang J. Osteopontin induces vascular endothelial growth factor expression in articular cartilage through PI3K/AKT and ERK1/2 signaling. Mol Med Rep. 2015;12:4708-4712 pubmed publisher
Regenfuß B, Dreisow M, Hos D, Masli S, Bock F, Cursiefen C. The Naïve Murine Cornea as a Model System to Identify Novel Endogenous Regulators of Lymphangiogenesis: TRAIL and rtPA. Lymphat Res Biol. 2015;13:76-84 pubmed publisher
Yue G, Lee J, Kwok H, Cheng L, Wong E, Jiang L, et al. Novel PI3K/AKT targeting anti-angiogenic activities of 4-vinylphenol, a new therapeutic potential of a well-known styrene metabolite. Sci Rep. 2015;5:11149 pubmed publisher
Yao H, Shi W, Wu J, Xu C, Wang J, Shao Y, et al. Endothelial Rac1 is essential for hematogenous metastasis to the lung. Oncotarget. 2015;6:17501-13 pubmed
Bauer A, Suckau J, Frank K, Desch A, Goertz L, Wagner A, et al. von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans. Blood. 2015;125:3153-63 pubmed publisher
Roma Lavisse C, Tagzirt M, Zawadzki C, Lorenzi R, Vincentelli A, Haulon S, et al. M1 and M2 macrophage proteolytic and angiogenic profile analysis in atherosclerotic patients reveals a distinctive profile in type 2 diabetes. Diab Vasc Dis Res. 2015;12:279-89 pubmed publisher
Wang F, Wang M, She Z, Fan K, Xu C, Chu B, et al. Collagen/chitosan based two-compartment and bi-functional dermal scaffolds for skin regeneration. Mater Sci Eng C Mater Biol Appl. 2015;52:155-62 pubmed publisher
Lee W, Pyun B, Kim S, Shim S, Nam J, Yoo J, et al. TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis. MAbs. 2015;7:957-68 pubmed publisher
Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y. The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation. PLoS ONE. 2015;10:e0124259 pubmed publisher
Pérez Sánchez L, Morera Díaz Y, Bequet Romero M, Ramses Hernández G, Rodríguez Y, Castro Velazco J, et al. Experimental studies of a vaccine formulation of recombinant human VEGF antigen with aluminum phosphate. Hum Vaccin Immunother. 2015;11:2030-7 pubmed publisher
Lee H, Xue J, Chou P, Zhou A, Yang P, Conrad C, et al. Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells. Oncotarget. 2015;6:10016-29 pubmed
Ota H, Takehara N, Aonuma T, Kabara M, Matsuki M, Yamauchi A, et al. Association between microalbuminuria predicting in-stent restenosis after myocardial infarction and cellular senescence of endothelial progenitor cells. PLoS ONE. 2015;10:e0123733 pubmed publisher
Lu K, Basu S. The natural compound chebulagic acid inhibits vascular endothelial growth factor A mediated regulation of endothelial cell functions. Sci Rep. 2015;5:9642 pubmed publisher
Kawase T, Tanaka T, Okuda K, Tsuchimochi M, Oda M, Hara T. Quantitative single-cell motility analysis of platelet-rich plasma-treated endothelial cells in vitro. Cytoskeleton (Hoboken). 2015;72:246-55 pubmed publisher
Birkenhauer E, Neethirajan S. A double-edged sword: the role of VEGF in wound repair and chemoattraction of opportunist pathogens. Int J Mol Sci. 2015;16:7159-72 pubmed publisher
Khayati F, Pérez Cano L, Maouche K, Sadoux A, Boutalbi Z, Podgorniak M, et al. EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF. Oncotarget. 2015;6:9766-80 pubmed
Chan K, Bernal A, Vickers M, Gohir W, Petrik J, Sloboda D. Early life exposure to undernutrition induces ER stress, apoptosis, and reduced vascularization in ovaries of adult rat offspring. Biol Reprod. 2015;92:110 pubmed publisher
Sukul M, Nguyen T, Min Y, Lee S, Lee B. Effect of Local Sustainable Release of BMP2-VEGF from Nano-Cellulose Loaded in Sponge Biphasic Calcium Phosphate on Bone Regeneration. Tissue Eng Part A. 2015;21:1822-36 pubmed publisher
Utzinger U, Baggett B, Weiss J, Hoying J, Edgar L. Large-scale time series microscopy of neovessel growth during angiogenesis. Angiogenesis. 2015;18:219-32 pubmed publisher
Liang M, Woodard L, Liang A, Luo J, Wilson M, Mitch W, et al. Protective role of insulin-like growth factor-1 receptor in endothelial cells against unilateral ureteral obstruction-induced renal fibrosis. Am J Pathol. 2015;185:1234-50 pubmed publisher
Marini M, Bertolai R, Ambrosini S, Sarchielli E, Vannelli G, Sgambati E. Differential expression of vascular endothelial growth factor in human fetal skeletal site-specific tissues: Mandible versus femur. Acta Histochem. 2015;117:228-34 pubmed publisher
Lopes F, Traina F, Almeida C, Leonardo F, Franco Penteado C, Garrido V, et al. Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea. Haematologica. 2015;100:730-9 pubmed publisher
Chuang J, Chen P, Tsao C, Chang A, Lein M, Lin C, et al. WISP-1 a novel angiogenic regulator of the CCN family promotes oral squamous cell carcinoma angiogenesis through VEGF-A expression. Oncotarget. 2015;6:4239-52 pubmed
Jiang X, Nguyen T, Tian W, Sung Y, Yuan K, Qian J, et al. Cyclosporine Does Not Prevent Microvascular Loss in Transplantation but Can Synergize With a Neutrophil Elastase Inhibitor, Elafin, to Maintain Graft Perfusion During Acute Rejection. Am J Transplant. 2015;15:1768-81 pubmed publisher
Mohandas A, Anisha B, Chennazhi K, Jayakumar R. Chitosan-hyaluronic acid/VEGF loaded fibrin nanoparticles composite sponges for enhancing angiogenesis in wounds. Colloids Surf B Biointerfaces. 2015;127:105-13 pubmed publisher
Gao J, Zheng W, Wang L, Song B. A disintegrin and metallproteinase 15 knockout decreases migration of fibroblast-like synoviocytes and inflammation in rheumatoid arthritis. Mol Med Rep. 2015;11:4389-96 pubmed publisher
Hollanders K, Van Bergen T, Kindt N, Castermans K, Leysen D, Vandewalle E, et al. The effect of AMA0428, a novel and potent ROCK inhibitor, in a model of neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 2015;56:1335-48 pubmed publisher
Ai W, Li J, Lin S, Li W, Liu C, Lv W. R-Smad signaling-mediated VEGF expression coordinately regulates endothelial cell differentiation of rat mesenchymal stem cells. Stem Cells Dev. 2015;24:1320-31 pubmed publisher
Sarig U, Nguyen E, Wang Y, Ting S, Bronshtein T, Sarig H, et al. Pushing the envelope in tissue engineering: ex vivo production of thick vascularized cardiac extracellular matrix constructs. Tissue Eng Part A. 2015;21:1507-19 pubmed publisher
Park S, Oh J, Kim Y, Park J, Park J, Hong H, et al. Intraocular pharmacokinetics of intravitreal vascular endothelial growth factor-Trap in a rabbit model. Eye (Lond). 2015;29:561-8 pubmed publisher
Wu W, Lien R, Liao P, Wang N, Chen Y, Chao A, et al. Serum levels of vascular endothelial growth factor and related factors after intravitreous bevacizumab injection for retinopathy of prematurity. JAMA Ophthalmol. 2015;133:391-7 pubmed publisher
Jung H, Kim Y, Lee H, Kwon H. Antiangiogenic activity of the lipophilic antimicrobial peptides from an endophytic bacterial strain isolated from red pepper leaf. Mol Cells. 2015;38:273-8 pubmed publisher
Chen W, Mao K, Hua Huy T, Bei Y, Liu Z, Dinh Xuan A. Fasudil inhibits prostate cancer-induced angiogenesis in vitro. Oncol Rep. 2014;32:2795-802 pubmed publisher
Bressan M, Yang P, Louie J, Navetta A, Garriock R, Mikawa T. Reciprocal myocardial-endocardial interactions pattern the delay in atrioventricular junction conduction. Development. 2014;141:4149-57 pubmed publisher
Koh S, Kim M, Lee K, Kim S, Kim J. RhoGDI2 is associated with HGF-mediated tumor invasion through VEGF in stomach cancer. Clin Exp Metastasis. 2014;31:805-15 pubmed publisher
Tawada M, Hayashi S, Ikegame Y, Nakashima S, Yoshida K. Possible involvement of tumor-producing VEGF-A in the recruitment of lymphatic endothelial progenitor cells from bone marrow. Oncol Rep. 2014;32:2359-64 pubmed publisher
Yang W, Chen J, Hsu K, Lin C, Wang S, Wang S, et al. Leptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells. Biochim Biophys Acta. 2014;1840:3483-93 pubmed publisher
Wang A, Rao V, Chen J, Lussier Y, Rehman J, Huang Y, et al. Role of FAM18B in diabetic retinopathy. Mol Vis. 2014;20:1146-59 pubmed
Zhao D, Pan C, Sun J, Gilbert C, Drews Elger K, Azzam D, et al. VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2. Oncogene. 2015;34:3107-19 pubmed publisher
Das M, Basak S, Ahmed M, Attramadal H, Duttaroy A. Connective tissue growth factor induces tube formation and IL-8 production in first trimester human placental trophoblast cells. Eur J Obstet Gynecol Reprod Biol. 2014;181:183-8 pubmed publisher
Kyadari M, Fatma T, Velpandian T, Malliga P, Bharat N, Fareha B. Antiangiogenic and antiproliferative assessment of cyanobacteria. Indian J Exp Biol. 2014;52:835-42 pubmed
Yafai Y, Eichler W, Iandiev I, Unterlauft J, Jochmann C, Wiedemann P, et al. Thrombospondin-1 is produced by retinal glial cells and inhibits the growth of vascular endothelial cells. Ophthalmic Res. 2014;52:81-8 pubmed publisher
Kanthou C, Dachs G, Lefley D, Steele A, Coralli Foxon C, Harris S, et al. Tumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristics. PLoS ONE. 2014;9:e104015 pubmed publisher
Ngo D, Farb M, Kikuchi R, Karki S, Tiwari S, Bigornia S, et al. Antiangiogenic actions of vascular endothelial growth factor-A165b, an inhibitory isoform of vascular endothelial growth factor-A, in human obesity. Circulation. 2014;130:1072-80 pubmed publisher
Najib S, Kowalski Chauvel A, Do C, Roche S, Cohen Jonathan Moyal E, Seva C. Progastrin a new pro-angiogenic factor in colorectal cancer. Oncogene. 2015;34:3120-30 pubmed publisher
Adelfinger M, Gentschev I, Grimm de Guibert J, Weibel S, Langbein Laugwitz J, Härtl B, et al. Evaluation of a new recombinant oncolytic vaccinia virus strain GLV-5b451 for feline mammary carcinoma therapy. PLoS ONE. 2014;9:e104337 pubmed publisher
Kere M, Siriboon C, Liao J, Lo N, Chiang H, Fan Y, et al. Vascular endothelial growth factor A improves quality of matured porcine oocytes and developing parthenotes. Domest Anim Endocrinol. 2014;49:60-9 pubmed publisher
Zhang W, Zhu C, Ye D, Xu L, Zhang X, Wu Q, et al. Porous silk scaffolds for delivery of growth factors and stem cells to enhance bone regeneration. PLoS ONE. 2014;9:e102371 pubmed publisher
Kim J, Chaudhary N, Seo H, Kim M, Shin T. Theasaponin E₁ as an effective ingredient for anti-angiogenesis and anti-obesity effects. Biosci Biotechnol Biochem. 2014;78:279-87 pubmed publisher
Litvinov J, Hagström A, Lopez Y, Adhikari M, Kourentzi K, Strych U, et al. Ultrasensitive immuno-detection using viral nanoparticles with modular assembly using genetically-directed biotinylation. Biotechnol Lett. 2014;36:1863-8 pubmed publisher
Lu C, Chen H, Chiang J, Jin Y, Kuo S, Wu T, et al. Quinazoline analog HMJ-30 inhibits angiogenesis: involvement of endothelial cell apoptosis through ROS-JNK-mediated death receptor 5 signaling. Oncol Rep. 2014;32:597-606 pubmed publisher
Wu Z, Rowe R, Lim K, Lin Y, Willis A, Tang Y, et al. A Snail1/Notch1 signalling axis controls embryonic vascular development. Nat Commun. 2014;5:3998 pubmed publisher
Hosoi M, Kumano K, Taoka K, Arai S, Kataoka K, Ueda K, et al. Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples. Exp Hematol. 2014;42:816-25 pubmed publisher
Haraguchi T, Kayashima T, Okazaki Y, Inoue J, Mineo S, Matsubara K, et al. Cecal succinate elevated by some dietary polyphenols may inhibit colon cancer cell proliferation and angiogenesis. J Agric Food Chem. 2014;62:5589-94 pubmed publisher
Underwood C, Edgar L, Hoying J, Weiss J. Cell-generated traction forces and the resulting matrix deformation modulate microvascular alignment and growth during angiogenesis. Am J Physiol Heart Circ Physiol. 2014;307:H152-64 pubmed publisher
Zeng Z, Zhu B. Arnebin-1 promotes the angiogenesis of human umbilical vein endothelial cells and accelerates the wound healing process in diabetic rats. J Ethnopharmacol. 2014;154:653-62 pubmed publisher
Giordano A, D Angelillo A, Romano S, D Arrigo P, Corcione N, Bisogni R, et al. Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells. Vascul Pharmacol. 2014;61:63-71 pubmed publisher
Nakagawa T, Matsushima T, Kawano S, Nakazawa Y, Kato Y, Adachi Y, et al. Lenvatinib in combination with golvatinib overcomes hepatocyte growth factor pathway-induced resistance to vascular endothelial growth factor receptor inhibitor. Cancer Sci. 2014;105:723-30 pubmed publisher
Mulyasasmita W, Cai L, Hori Y, Heilshorn S. Avidity-controlled delivery of angiogenic peptides from injectable molecular-recognition hydrogels. Tissue Eng Part A. 2014;20:2102-14 pubmed publisher
Berendsen A, Pinnow E, Maeda A, Brown A, McCartney Francis N, Kram V, et al. Biglycan modulates angiogenesis and bone formation during fracture healing. Matrix Biol. 2014;35:223-31 pubmed publisher
Foubert P, Squiban C, Holler V, Buard V, Déan C, Levy B, et al. Strategies to Enhance the Efficiency of Endothelial Progenitor Cell Therapy by Ephrin B2 Pretreatment and Coadministration with Smooth Muscle Progenitor Cells on Vascular Function During the Wound-Healing Process in Irradiated or Nonirradiated Condit. Cell Transplant. 2015;24:1343-61 pubmed publisher
Ahn J, Kim H, Woo S, Park J, Park S, Hwang D, et al. Pharmacokinetics of intravitreally injected bevacizumab in vitrectomized eyes. J Ocul Pharmacol Ther. 2013;29:612-8 pubmed publisher
Galv o A, Henriques S, Pestka D, Lukasik K, Skarzynski D, Mateus L, et al. Equine luteal function regulation may depend on the interaction between cytokines and vascular endothelial growth factor: an in vitro study. Biol Reprod. 2012;86:187 pubmed publisher
Hayakawa K, Pham L, Som A, Lee B, Guo S, Lo E, et al. Vascular endothelial growth factor regulates the migration of oligodendrocyte precursor cells. J Neurosci. 2011;31:10666-70 pubmed publisher
Poche R, Saik J, West J, Dickinson M. The mouse cornea as a transplantation site for live imaging of engineered tissue constructs. Cold Spring Harb Protoc. 2010;2010:pdb.prot5416 pubmed publisher
Davani B, Ikonomou L, Raaka B, Geras Raaka E, Morton R, Marcus Samuels B, et al. Human islet-derived precursor cells are mesenchymal stromal cells that differentiate and mature to hormone-expressing cells in vivo. Stem Cells. 2007;25:3215-22 pubmed
Ferrara N, Davis Smyth T. The biology of vascular endothelial growth factor. Endocr Rev. 1997;18:4-25 pubmed
Conn G, Soderman D, Schaeffer M, Wile M, Hatcher V, Thomas K. Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line. Proc Natl Acad Sci U S A. 1990;87:1323-7 pubmed
product information
Catalog Number :
V7259
Product Name :
Vascular Endothelial Growth Factor human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA