Reference |
---|
Draper A, Wilson Z, Maile C, Faccenda D, Campanella M, Piercy R. Species-specific consequences of an E40K missense mutation in superoxide dismutase 1 (SOD1). FASEB J. 2020;34:458-473 pubmed publisher
|
Jiang M, Kang Y, Sewastianik T, Wang J, Tanton H, Alder K, et al. BCL9 provides multi-cellular communication properties in colorectal cancer by interacting with paraspeckle proteins. Nat Commun. 2020;11:19 pubmed publisher
|
Rault L, Johnson E, O Neal S, Chen R, McComic S, Swale D, et al. Age- and sex-related ABC transporter expression in pyrethroid-susceptible and -resistant Aedes aegypti. Sci Rep. 2019;9:19551 pubmed publisher
|
Chabi S, Uzan B, Naguibneva I, Rucci J, Fahy L, Calvo J, et al. Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors. Cell Rep. 2019;29:2307-2320.e6 pubmed publisher
|
Ohshima M, Kamei S, Fushimi H, Mima S, Yamada T, Yamamoto T. Prediction of Drug Permeability Using In Vitro Blood-Brain Barrier Models with Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells. Biores Open Access. 2019;8:200-209 pubmed publisher
|
Hayes H, Nicolini A, Arrowood C, Chvatal S, Wolfson D, Cho H, et al. Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology. Sci Rep. 2019;9:11893 pubmed publisher
|
Koh J, Itahana Y, Mendenhall I, Low D, Soh E, Guo A, et al. ABCB1 protects bat cells from DNA damage induced by genotoxic compounds. Nat Commun. 2019;10:2820 pubmed publisher
|
Greenwood D, Dos Santos M, Huang S, Russell M, Collinson L, Macrae J, et al. Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages. Science. 2019;364:1279-1282 pubmed publisher
|
McAleer C, Long C, Elbrecht D, Sasserath T, Bridges L, Rumsey J, et al. Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics. Sci Transl Med. 2019;11: pubmed publisher
|
Wiebe S, Plain A, Pan W, O Neill D, Braam B, Alexander R. NHE8 attenuates Ca2+ influx into NRK cells and the proximal tubule epithelium. Am J Physiol Renal Physiol. 2019;317:F240-F253 pubmed publisher
|
Janssens G, Lin X, Millán Ariño L, Kavšek A, Sen I, Seinstra R, et al. Transcriptomics-Based Screening Identifies Pharmacological Inhibition of Hsp90 as a Means to Defer Aging. Cell Rep. 2019;27:467-480.e6 pubmed publisher
|
Zhou X, Ma Y, Liu F, Gu C, Wang X, Xia H, et al. Melanocyte Chitosan/Gelatin Composite Fabrication with Human Outer Root Sheath-Derived Cells to Produce Pigment. Sci Rep. 2019;9:5198 pubmed publisher
|
Arnold Y, Thorens J, Bernard S, Kalia Y. Drug Transport across Porcine Intestine Using an Ussing Chamber System: Regional Differences and the Effect of P-Glycoprotein and CYP3A4 Activity on Drug Absorption. Pharmaceutics. 2019;11: pubmed publisher
|
Fujioka Y, Nishide S, Ose T, Suzuki T, Kato I, Fukuhara H, et al. A Sialylated Voltage-Dependent Ca2+ Channel Binds Hemagglutinin and Mediates Influenza A Virus Entry into Mammalian Cells. Cell Host Microbe. 2018;23:809-818.e5 pubmed publisher
|
Qamar H, Qayyum R, Salma U, Khan S, Khan T, Shah A. Vascular mechanisms underlying the hypotensive effect of Rumex acetosa. Pharm Biol. 2018;56:225-234 pubmed publisher
|
Xiao J, Rijal P, Schimanski L, Tharkeshwar A, Wright E, Annaert W, et al. Characterization of Influenza Virus Pseudotyped with Ebolavirus Glycoprotein. J Virol. 2018;92: pubmed publisher
|
Aggarwal A, Parai M, Shetty N, Wallis D, Woolhiser L, Hastings C, et al. Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13. Cell. 2017;170:249-259.e25 pubmed publisher
|
Stancill J, Cartailler J, Clayton H, O Connor J, Dickerson M, Dadi P, et al. Chronic ?-Cell Depolarization Impairs ?-Cell Identity by Disrupting a Network of Ca2+-Regulated Genes. Diabetes. 2017;66:2175-2187 pubmed publisher
|
Heo S, Thorpe S, Driscoll T, Duncan R, Lee D, Mauck R. Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells. Sci Rep. 2015;5:16895 pubmed publisher
|
Ikeda K, Ueda C, Yamada K, Nakamura A, Hatsuda Y, Kawanishi S, et al. Carrier-mediated placental transport of cimetidine and valproic acid across differentiating JEG-3 cell layers. Pharmazie. 2015;70:471-6 pubmed
|
Ufuk A, Somers G, Houston J, Galetin A. In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383. Pharm Res. 2015;32:3937-51 pubmed publisher
|
Kim H, Lee K, Kim Y, Choi Y, Lee J, Choi C, et al. P-glycoprotein confers acquired resistance to 17-DMAG in lung cancers with an ALK rearrangement. BMC Cancer. 2015;15:553 pubmed publisher
|
Redaelli S, Perini P, Ceccon M, Piazza R, Rigolio R, Mauri M, et al. In vitro and in vivo identification of ABCB1 as an efflux transporter of bosutinib. J Hematol Oncol. 2015;8:81 pubmed publisher
|
Mo L, Pospichalova V, Huang Z, Murphy S, Payne S, Wang F, et al. Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells. PLoS ONE. 2015;10:e0131579 pubmed publisher
|
Joseph N, Tom Esther N, Télesphore Benoît N, Paul Désiré D, Oumarou Bibi Farouck A, Théophile D, et al. Effects of the aqueous extract of Pittosporum mannii Hook. f. (Pittosporaceae) stem barks on spontaneous and spasmogen-induced contractile activity of isolated rat duodenum. J Ethnopharmacol. 2015;172:1-9 pubmed publisher
|
Ohura K, Nakada Y, Kotani S, Imai T. Design of Fexofenadine Prodrugs Based on Tissue-Specific Esterase Activity and Their Dissimilar Recognition by P-Glycoprotein. J Pharm Sci. 2015;104:3076-83 pubmed publisher
|
Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher
|
Sadiq M, Uchida Y, Hoshi Y, Tachikawa M, Terasaki T, Hammarlund Udenaes M. Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport. PLoS ONE. 2015;10:e0118638 pubmed publisher
|
Li M, de Graaf I, de Jager M, Groothuis G. Rat precision-cut intestinal slices to study P-gp activity and the potency of its inhibitors ex vivo. Toxicol In Vitro. 2015;29:1070-8 pubmed publisher
|
Tian D, Jia W, Liu X, Wang D, Liu J, Dong J, et al. Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots (Danshen). Acta Pharmacol Sin. 2015;36:627-43 pubmed publisher
|
Micsik T, Lőrincz A, Mersich T, Baranyai Z, Besznyák I, Dede K, et al. Decreased functional activity of multidrug resistance protein in primary colorectal cancer. Diagn Pathol. 2015;10:26 pubmed publisher
|
Surampalli G, Nanjwade B, Patil P. Comprehensive cytotoxic evaluation of morin, a bioflavonoid against verapamil on rat gastrointestinal epithelium for novel pharmaceutical application involving P-glycoprotein inhibition. J Pharm Pharmacol. 2015;67:1083-99 pubmed publisher
|
Mennecozzi M, Landesmann B, Palosaari T, Harris G, Whelan M. Sex differences in liver toxicity-do female and male human primary hepatocytes react differently to toxicants in vitro?. PLoS ONE. 2015;10:e0122786 pubmed publisher
|
Regueiro J, OlguÃn N, Simal Gándara J, Suñol C. Toxicity evaluation of new agricultural fungicides in primary cultured cortical neurons. Environ Res. 2015;140:37-44 pubmed publisher
|
Wityak J, McGee K, Conlon M, Song R, Duffy B, Clayton B, et al. Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors. J Med Chem. 2015;58:2967-87 pubmed publisher
|
Lim J, Li L, Kakhlon O, Myerowitz R, Raben N. Defects in calcium homeostasis and mitochondria can be reversed in Pompe disease. Autophagy. 2015;11:385-402 pubmed publisher
|
Chong K, Hsu C, Hung T, Hu H, Huang T, Wang T, et al. Wnt pathway activation and ABCB1 expression account for attenuation of proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells. Cancer Biol Ther. 2015;16:149-59 pubmed publisher
|
Wong P, Demircioglu F, Ghazaly E, Alrawashdeh W, Stratford M, Scudamore C, et al. Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread. Cancer Cell. 2015;27:123-37 pubmed publisher
|
Bridges E, Harris A. Vascular-promoting therapy reduced tumor growth and progression by improving chemotherapy efficacy. Cancer Cell. 2015;27:7-9 pubmed publisher
|
Janbaz K, Qayyum A, Saqib F, Imran I, Zia Ul Haq M, De Feo V. Bronchodilator, vasodilator and spasmolytic activities of Cymbopogon martinii. J Physiol Pharmacol. 2014;65:859-66 pubmed
|
Yano K, Mita S, Morimoto K, Haraguchi T, Arakawa H, Yoshida M, et al. Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity, Measured with a Sensor. J Pharm Sci. 2015;104:2789-94 pubmed publisher
|
Stott L, Schnell S, Hogstrand C, Owen S, Bury N. A primary fish gill cell culture model to assess pharmaceutical uptake and efflux: evidence for passive and facilitated transport. Aquat Toxicol. 2015;159:127-37 pubmed publisher
|
Compton L, Reschke B, Friend J, Powell M, Vertes A. Remote laser ablation electrospray ionization mass spectrometry for non-proximate analysis of biological tissues. Rapid Commun Mass Spectrom. 2015;29:67-73 pubmed publisher
|
Ortega P, Custódio M, Zanotto F. Characterization of cadmium plasma membrane transport in gills of a mangrove crab Ucides cordatus. Aquat Toxicol. 2014;157:21-9 pubmed publisher
|
Kibria G, Hatakeyama H, Akiyama K, Hida K, Harashima H. Comparative study of the sensitivities of cancer cells to doxorubicin, and relationships between the effect of the drug-efflux pump P-gp. Biol Pharm Bull. 2014;37:1926-35 pubmed
|
Maneshi M, Sachs F, Hua S. A Threshold Shear Force for Calcium Influx in an Astrocyte Model of Traumatic Brain Injury. J Neurotrauma. 2015;32:1020-9 pubmed publisher
|
Besser J, Malan D, Wystub K, Bachmann A, Wietelmann A, Sasse P, et al. MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization. PLoS ONE. 2014;9:e113449 pubmed publisher
|
Singhal A, Jie L, Kumar P, Hong G, Leow M, Paleja B, et al. Metformin as adjunct antituberculosis therapy. Sci Transl Med. 2014;6:263ra159 pubmed publisher
|
Loh C, Suwanarusk R, Lee Y, Chan K, Choy K, Renia L, et al. Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay. PLoS ONE. 2014;9:e110800 pubmed publisher
|
Grammen C, Baes M, Haenen S, Verguts J, Augustyns K, ZYDOWSKY T, et al. Vaginal expression of efflux transporters and the potential impact on the disposition of microbicides in vitro and in rabbits. Mol Pharm. 2014;11:4405-14 pubmed publisher
|
Huang J, Saharan S, McCammond A, Balaji S. Belhassen tachycardia in a 19-month-old child. J Pediatr. 2015;166:200 pubmed publisher
|
Nishimoto R, Kashio M, Tominaga M. Propofol-induced pain sensation involves multiple mechanisms in sensory neurons. Pflugers Arch. 2015;467:2011-20 pubmed publisher
|
Mohamed L, Kaddoumi A. Tacrine sinusoidal uptake and biliary excretion in sandwich-cultured primary rat hepatocytes. J Pharm Pharm Sci. 2014;17:427-38 pubmed
|
Kam Y, Das T, Tian H, Foroutan P, Ruiz E, Martinez G, et al. Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". Int J Cancer. 2015;136:E188-96 pubmed publisher
|
Liu J, Wang J, Zhou J, Tang X, Xu L, Shen T, et al. Enhanced brain delivery of lamotrigine with Pluronic(®) P123-based nanocarrier. Int J Nanomedicine. 2014;9:3923-35 pubmed publisher
|
Gagliano T, Gentilin E, Benfini K, Di Pasquale C, Tassinari M, Falletta S, et al. Mitotane enhances doxorubicin cytotoxic activity by inhibiting P-gp in human adrenocortical carcinoma cells. Endocrine. 2014;47:943-51 pubmed publisher
|
Uchida Y, Ohtsuki S, Terasaki T. Pharmacoproteomics-based reconstruction of in vivo P-glycoprotein function at blood-brain barrier and brain distribution of substrate verapamil in pentylenetetrazole-kindled epilepsy, spontaneous epilepsy, and phenytoin treatment models. Drug Metab Dispos. 2014;42:1719-26 pubmed publisher
|
Willenberg I, von Elsner L, Steinberg P, Schebb N. Development of an online-SPE-LC-MS method for the investigation of the intestinal absorption of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) and its bacterial metabolite PHIP-M1 in a Caco-2 Transwell system. Food Chem. 2015;166:537-543 pubmed publisher
|
Fujii S, Setoguchi C, Kawazu K, Hosoya K. Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats. Invest Ophthalmol Vis Sci. 2014;55:4650-8 pubmed publisher
|
Ali A, Mutchnick S, Liberati D, Diebel L. Salutary effect of calcium channel blockade following hypoxic and septic insult. J Trauma Acute Care Surg. 2014;77:40-6; discussion 45-6 pubmed publisher
|
Rodrigues M, Dias L, Rennó A, Sousa N, Smaal A, da Silva D, et al. Rat atrial responses to Bothrops jararacussu (jararacuçu) snake venom. Toxicology. 2014;323:109-24 pubmed publisher
|
Niess H, Camaj P, Renner A, Ischenko I, Zhao Y, Krebs S, et al. Side population cells of pancreatic cancer show characteristics of cancer stem cells responsible for resistance and metastasis. Target Oncol. 2015;10:215-27 pubmed publisher
|
Uchida Y, Wakayama K, Ohtsuki S, Chiba M, Ohe T, Ishii Y, et al. Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys. J Pharmacol Exp Ther. 2014;350:578-88 pubmed publisher
|
Jin X, Muntean B, Aal Aaboda M, Duan Q, Zhou J, Nauli S. L-type calcium channel modulates cystic kidney phenotype. Biochim Biophys Acta. 2014;1842:1518-26 pubmed publisher
|
Pandey A, Sikdar S. Depression biased non-Hebbian spike-timing-dependent synaptic plasticity in the rat subiculum. J Physiol. 2014;592:3537-57 pubmed publisher
|
Wilisch Neumann A, Pachow D, Wallesch M, Petermann A, Bohmer F, Kirches E, et al. Re-evaluation of cytostatic therapies for meningiomas in vitro. J Cancer Res Clin Oncol. 2014;140:1343-52 pubmed publisher
|
Nagaya Y, Nozaki Y, Kobayashi K, Takenaka O, Nakatani Y, Kusano K, et al. Utility of cerebrospinal fluid drug concentration as a surrogate for unbound brain concentration in nonhuman primates. Drug Metab Pharmacokinet. 2014;29:419-26 pubmed
|
Seip K, Jensen H, Kieu T, Gjelstad A, Pedersen Bjergaard S. Salt effects in electromembrane extraction. J Chromatogr A. 2014;1347:1-7 pubmed publisher
|
McCarthy M, Auda G, Agrawal S, Taylor A, Backstrom Z, Mondal D, et al. In vivo anticancer synergy mechanism of doxorubicin and verapamil combination treatment is impaired in BALB/c mice with metastatic breast cancer. Exp Mol Pathol. 2014;97:6-15 pubmed publisher
|
Izdes S, Altintas N, Soykut C. Acute respiratory distress syndrome after verapamil intoxication: case report and literature review. Acta Clin Belg. 2014;69:116-9 pubmed publisher
|
Siddiqi H, Majeed A, Gilani A. Pharmacological basis for the medicinal use of Wrightia tinctoria in hypertension and dyslipidemia. J Cardiovasc Pharmacol. 2014;64:151-63 pubmed publisher
|
Horita Y, Doi N. Comparative study of the effects of antituberculosis drugs and antiretroviral drugs on cytochrome P450 3A4 and P-glycoprotein. Antimicrob Agents Chemother. 2014;58:3168-76 pubmed publisher
|
Frink L, Weatherly C, Armstrong D. Water determination in active pharmaceutical ingredients using ionic liquid headspace gas chromatography and two different detection protocols. J Pharm Biomed Anal. 2014;94:111-7 pubmed publisher
|
Adams K, Szumowski J, Ramakrishnan L. Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs. J Infect Dis. 2014;210:456-66 pubmed publisher
|
Tauber P, Penton D, Stindl J, Humberg E, Tegtmeier I, Sterner C, et al. Pharmacology and pathophysiology of mutated KCNJ5 found in adrenal aldosterone-producing adenomas. Endocrinology. 2014;155:1353-62 pubmed publisher
|
Jordan G, Carson C, Lipshultz L. Minimally invasive treatment of Peyronie's disease: evidence-based progress. BJU Int. 2014;114:16-24 pubmed publisher
|
Zhang Y, Hu Y, Feng Y, Kodithuwakku N, Fang W, Li Y, et al. The inhibitory and combinative mechanism of HZ08 with P-glycoprotein expressed on the membrane of Caco-2 cell line. Toxicol Appl Pharmacol. 2014;274:232-9 pubmed publisher
|
Canan T, Vaseghi M, Girsky M, Yang E. A complex rhythm treated simply: fascicular ventricular tachycardia. Am J Med. 2014;127:601-4 pubmed publisher
|
Ledon J, Savas J, França K, Chacon A, Nouri K. Intralesional treatment for keloids and hypertrophic scars: a review. Dermatol Surg. 2013;39:1745-57 pubmed publisher
|
Tsubaki M, Komai M, Itoh T, Imano M, Sakamoto K, Shimaoka H, et al. By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells. Leuk Res. 2014;38:121-30 pubmed publisher
|
Atabak S, Taziki O, Argani H, Abolghasemi R, Zangneh H, Rahmani L. Effects of oral enalapril and verapamil on dialysis adequacy and solute clearance in chronic ambulatory peritoneal dialysis. Saudi J Kidney Dis Transpl. 2013;24:1170-4 pubmed publisher
|
Park S, Moon I. Round window membrane vibration may increase the effect of intratympanic dexamethasone injection. Laryngoscope. 2014;124:1444-51 pubmed publisher
|
Yu Y, Lu Y, Zhao X, Li X, Yin Z. Intestinal absorption of raltitrexed and evaluation of the effects of absorption enhancers. Pharmazie. 2013;68:732-43 pubmed
|
Cadagan D, Merry S. Circumvention of inherent or acquired cytotoxic drug resistance in vitro using combinations of modulating agents. Anticancer Res. 2013;33:4381-7 pubmed
|
Aihara E, Hentz C, Korman A, Perry N, Prasad V, Shull G, et al. In vivo epithelial wound repair requires mobilization of endogenous intracellular and extracellular calcium. J Biol Chem. 2013;288:33585-97 pubmed publisher
|
Yang C, Zhang T, Li Z, Xu L, Liu F, Ruan J, et al. P-glycoprotein is responsible for the poor intestinal absorption and low toxicity of oral aconitine: in vitro, in situ, in vivo and in silico studies. Toxicol Appl Pharmacol. 2013;273:561-8 pubmed publisher
|
Savage J, Meaney M, Brennan G, Hoey E, Trudgett A, Fairweather I. Increased action of triclabendazole (TCBZ) in vitro against a TCBZ-resistant isolate of Fasciola hepatica following its co-incubation with the P-glycoprotein inhibitor, R(+)-verapamil. Exp Parasitol. 2013;135:642-53 pubmed publisher
|
Soudy R, Chen C, Kaur K. Novel peptide-doxorubucin conjugates for targeting breast cancer cells including the multidrug resistant cells. J Med Chem. 2013;56:7564-73 pubmed publisher
|
Ribeiro Filho J, Calheiros A, Vieira de Abreu A, de Carvalho K, da Silva Mendes D, Melo C, et al. Curine inhibits eosinophil activation and airway hyper-responsiveness in a mouse model of allergic asthma. Toxicol Appl Pharmacol. 2013;273:19-26 pubmed publisher
|
Pfeffer A, Williams S. Annals of Emergency Medicine Journal Club. Treatment of calcium channel blocker poisoning: should we re-prioritize our potpourri of treatment options?. Ann Emerg Med. 2013;62:273-4 pubmed publisher
|
Bao Q, Niess H, Djafarzadeh R, Zhao Y, Schwarz B, Angele M, et al. Recombinant TIMP-1-GPI inhibits growth of fibrosarcoma and enhances tumor sensitivity to doxorubicin. Target Oncol. 2014;9:251-61 pubmed publisher
|
Irnaten M, Barry R, Wallace D, Docherty N, Quill B, Clark A, et al. Elevated maxi-K(+) ion channel current in glaucomatous lamina cribrosa cells. Exp Eye Res. 2013;115:224-9 pubmed publisher
|
Sridhar V, Surya Sandeep M, Ravindra Babu P, Naveen Babu K. Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using felodipine and hesperetin in combination in Wistar rats and everted rat gut sacs in vitro. Phytother Res. 2014;28:699-705 pubmed publisher
|
Zarbin M. Combination therapy to reduce conjunctival scarring after glaucoma surgery. JAMA Ophthalmol. 2013;131:1123 pubmed publisher
|
Gupta S, Tyagi S, Almeida D, Maiga M, Ammerman N, Bishai W. Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor. Am J Respir Crit Care Med. 2013;188:600-7 pubmed publisher
|
Feldmann M, Asselin M, Liu J, Wang S, McMahon A, Anton Rodriguez J, et al. P-glycoprotein expression and function in patients with temporal lobe epilepsy: a case-control study. Lancet Neurol. 2013;12:777-85 pubmed publisher
|
Resztak M, Główka F. Stereoselective CZE method for analysis of verapamil and norverapamil in human plasma. Acta Pol Pharm. 2013;70:395-401 pubmed
|
Calcinaghi N, Wyss M, Jolivet R, Singh A, Keller A, Winnik S, et al. Multimodal imaging in rats reveals impaired neurovascular coupling in sustained hypertension. Stroke. 2013;44:1957-64 pubmed publisher
|
Palermo A, Giglia G, Cosentino G, Raieli V, Brighina F, Fierro B. Two cases of cluster headache effectively treated with levetiracetam. Funct Neurol. 2013;28:63-4 pubmed
|
Steinbach C, Fedorova G, Prokes M, Grabicova K, Machova J, Grabic R, et al. Toxic effects, bioconcentration and depuration of verapamil in the early life stages of common carp (Cyprinus carpio L.). Sci Total Environ. 2013;461-462:198-206 pubmed publisher
|
Li L, Li J, Lou H. [Study on in situ intestinal absorption of baicalin contained in Tiangou Jiangya capsules]. Zhongguo Zhong Yao Za Zhi. 2013;38:894-8 pubmed
|
Wang T, Hu N, Cao J, Wu J, Su K, Wang P. A cardiomyocyte-based biosensor for antiarrhythmic drug evaluation by simultaneously monitoring cell growth and beating. Biosens Bioelectron. 2013;49:9-13 pubmed publisher
|
McDonough C, Gong Y, Padmanabhan S, Burkley B, Langaee T, Melander O, et al. Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes. Hypertension. 2013;62:48-54 pubmed publisher
|
Neuhoff S, Yeo K, Barter Z, Jamei M, Turner D, Rostami Hodjegan A. Application of permeability-limited physiologically-based pharmacokinetic models: part II - prediction of P-glycoprotein mediated drug-drug interactions with digoxin. J Pharm Sci. 2013;102:3161-73 pubmed publisher
|
Levine M, Curry S, Padilla Jones A, Ruha A. Critical care management of verapamil and diltiazem overdose with a focus on vasopressors: a 25-year experience at a single center. Ann Emerg Med. 2013;62:252-8 pubmed publisher
|
Jia W, Zhu Z, Zhang T, Fan G, Fan P, Liu Y, et al. Treatment of malignant ascites with a combination of chemotherapy drugs and intraperitoneal perfusion of verapamil. Cancer Chemother Pharmacol. 2013;71:1585-90 pubmed publisher
|
Lautenschläger J, Prell T, Ruhmer J, Weidemann L, Witte O, Grosskreutz J. Overexpression of human mutated G93A SOD1 changes dynamics of the ER mitochondria calcium cycle specifically in mouse embryonic motor neurons. Exp Neurol. 2013;247:91-100 pubmed publisher
|
Mehta R, Kelleher D, Preece A, Hughes S, Crater G. Effect of verapamil on systemic exposure and safety of umeclidinium and vilanterol: a randomized and open-label study. Int J Chron Obstruct Pulmon Dis. 2013;8:159-67 pubmed publisher
|
Olson K. What is the best treatment for acute calcium channel blocker overdose?. Ann Emerg Med. 2013;62:259-61 pubmed publisher
|
Zhang C, Chanteux H, Zuo Z, Kwan P, Baum L. Potential role for human P-glycoprotein in the transport of lacosamide. Epilepsia. 2013;54:1154-60 pubmed publisher
|
Hung C, Chiou M, Teng Y, Hsieh Y, Huang C, Lane H. Functional impact of ABCB1 variants on interactions between P-glycoprotein and methadone. PLoS ONE. 2013;8:e59419 pubmed publisher
|
Liang P, Lan F, Lee A, Gong T, Sanchez Freire V, Wang Y, et al. Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation. 2013;127:1677-91 pubmed publisher
|
Macha S, Sennewald R, Rose P, Schoene K, Pinnetti S, Woerle H, et al. Lack of clinically relevant drug-drug interaction between empagliflozin, a sodium glucose cotransporter 2 inhibitor, and verapamil, ramipril, or digoxin in healthy volunteers. Clin Ther. 2013;35:226-35 pubmed publisher
|
Zhang L, Ouyang M, Ganellin C, Thomas S. The slow afterhyperpolarization: a target of ?1-adrenergic signaling in hippocampus-dependent memory retrieval. J Neurosci. 2013;33:5006-16 pubmed publisher
|
Zhang D, Li Y, Shu C, Ruan Z, Chen W, Yiu A, et al. Bipiperidinyl derivatives of 23-hydroxybetulinic acid reverse resistance of HepG2/ADM and MCF-7/ADR cells. Anticancer Drugs. 2013;24:441-54 pubmed publisher
|
Wang J, Wang Y, Ran R, Liu Y, Zheng C, Jiang L, et al. [Study on the release and mechanism of carbon nanotubes loaded with verapamil hydrochloride in vitro]. Zhong Yao Cai. 2012;35:1500-7 pubmed
|
Li R, Wei M, Shao J. Effects of verapamil on the immediate-early gene expression of bone marrow mesenchymal stem cells stimulated by mechanical strain in vitro. Med Sci Monit Basic Res. 2013;19:68-75 pubmed publisher
|
Zhang J, Cao H, Zhang Y, Zhang Y, Ma J, Wang J, et al. Nephroprotective effect of calcium channel blockers against toxicity of lead exposure in mice. Toxicol Lett. 2013;218:273-80 pubmed publisher
|
Duan L, Yan Y, Sun Y, Zhao B, Hu W, Li G. Contribution of TRPV1 and multidrug resistance proteins in the permeation of capsaicin across different intestinal regions. Int J Pharm. 2013;445:134-40 pubmed publisher
|
Shen J, Gao F, Yin T, Zhang H, Ma M, Yang Y, et al. cRGD-functionalized polymeric magnetic nanoparticles as a dual-drug delivery system for safe targeted cancer therapy. Pharmacol Res. 2013;70:102-15 pubmed publisher
|
Stein A, Dekel Y. [Review of Peyronie's disease]. Harefuah. 2012;151:638-40, 653 pubmed
|
Ke A, Eyal S, Chung F, Link J, Mankoff D, Muzi M, et al. Modeling cyclosporine A inhibition of the distribution of a P-glycoprotein PET ligand, 11C-verapamil, into the maternal brain and fetal liver of the pregnant nonhuman primate: impact of tissue blood flow and site of inhibition. J Nucl Med. 2013;54:437-46 pubmed publisher
|
Garro H, Elizari M, Baranchuk A, Femenia F, Chiale P. A reappraisal on lidocaine-sensitive repetitive, uniform atrial tachycardia. Ann Noninvasive Electrocardiol. 2013;18:1-11 pubmed publisher
|
Rong Z, Xu Y, Zhang C, Xiang D, Li X, Liu D. Evaluation of intestinal absorption of amtolmetin guacyl in rats: breast cancer resistant protein as a primary barrier of oral bioavailability. Life Sci. 2013;92:245-51 pubmed publisher
|
Saksena S, Priyamvada S, Kumar A, Akhtar M, Soni V, Anbazhagan A, et al. Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2013;304:G615-22 pubmed publisher
|
Incecayir T, Tsume Y, Amidon G. Comparison of the permeability of metoprolol and labetalol in rat, mouse, and Caco-2 cells: use as a reference standard for BCS classification. Mol Pharm. 2013;10:958-66 pubmed publisher
|
Palmer D, Levina M, Douroumis D, Maniruzzaman M, Morgan D, Farrell T, et al. Mechanism of synergistic interactions and its influence on drug release from extended release matrices manufactured using binary mixtures of polyethylene oxide and sodium carboxymethylcellulose. Colloids Surf B Biointerfaces. 2013;104:174-80 pubmed publisher
|
Tang J, Wang Y, Wang D, Wang Y, Xu Z, Racette K, et al. Key structure of brij for overcoming multidrug resistance in cancer. Biomacromolecules. 2013;14:424-30 pubmed publisher
|
Ishigami M, Tominaga Y, Nagao K, Kimura Y, Matsuo M, Kioka N, et al. ATPase activity of nucleotide binding domains of human MDR3 in the context of MDR1. Biochim Biophys Acta. 2013;1831:683-90 pubmed publisher
|
Stengaard C, Eiskjær H, Jensen H. [Fulminant acute heart failure following intravenous bolus administration of verapamil in a patient with supraventricular tachycardia]. Ugeskr Laeger. 2013;175:54-5 pubmed
|
Yagnik G, Korte A, Lee Y. Multiplex mass spectrometry imaging for latent fingerprints. J Mass Spectrom. 2013;48:100-4 pubmed publisher
|
Ding X, Ghobarah H, Zhang X, Jaochico A, Liu X, Deshmukh G, et al. High-throughput liquid chromatography/mass spectrometry method for the quantitation of small molecules using accurate mass technologies in supporting discovery drug screening. Rapid Commun Mass Spectrom. 2013;27:401-8 pubmed publisher
|
Chen L, Feng P, Li Y, Zhou D. Influences of "spasmolytic powder" on pgp expression of Coriaria Lactone-kindling drug-resistant epileptic rat model. J Mol Neurosci. 2013;51:1-8 pubmed publisher
|
Schmalhofer W, Swensen A, Thomas B, Felix J, Haedo R, Solly K, et al. A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel. Assay Drug Dev Technol. 2010;8:714-26 pubmed publisher
|
Ekins S, Williams A, Xu J. A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug Metab Dispos. 2010;38:2302-8 pubmed publisher
|
Greene N, Fisk L, Naven R, Note R, Patel M, Pelletier D. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol. 2010;23:1215-22 pubmed publisher
|
Zhang Y, Guiguemde W, Sigal M, Zhu F, Connelly M, Nwaka S, et al. Synthesis and structure-activity relationships of antimalarial 4-oxo-3-carboxyl quinolones. Bioorg Med Chem. 2010;18:2756-66 pubmed publisher
|
Nepveu F, Kim S, Boyer J, Chatriant O, Ibrahim H, Reybier K, et al. Synthesis and antiplasmodial activity of new indolone N-oxide derivatives. J Med Chem. 2010;53:699-714 pubmed publisher
|
Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher
|
Donnenberg V, Meyer E, Donnenberg A. Measurement of multiple drug resistance transporter activity in putative cancer stem/progenitor cells. Methods Mol Biol. 2009;568:261-79 pubmed publisher
|
Cohen V, Jellinek S, Fancher L, Sangwan G, Wakslak M, Marquart E, et al. Tarka® (trandolapril/verapamil hydrochloride extended-release) overdose. J Emerg Med. 2011;40:291-5 pubmed publisher
|
Soh P, Witkowski B, Olagnier D, Nicolau M, Garcia Alvarez M, Berry A, et al. In vitro and in vivo properties of ellagic acid in malaria treatment. Antimicrob Agents Chemother. 2009;53:1100-6 pubmed publisher
|
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
|
Kolomytkin O, Marino A, Sadasivan K, Wolf R, Albright J. Intracellular signaling mechanisms of interleukin-1beta in synovial fibroblasts. Am J Physiol. 1999;276:C9-C15 pubmed publisher
|
Shiina Y, Kaneda M, Matsuyama K, Tanaka K, Hiroi M, Doi K. Role of the extracellular Ca2+ on the intracellular Ca2+ changes in fertilized and activated mouse oocytes. J Reprod Fertil. 1993;97:143-50 pubmed
|
Baky S, Singh B. Verapamil hydrochloride: pharmacological properties and role in cardiovascular therapeutics. Pharmacotherapy. 1982;2:328-353 pubmed
|
Matsuzaki A, Shimura H, Okuda A, Ohtsu M, Sasaki M, Onodera K, et al. Mechanism of selective killing by dilinoleoylglycerol of cells transformed by the E1A gene of adenovirus type 12. Cancer Res. 1989;49:5702-7 pubmed
|