Published Application/Species/Sample/Dilution | Reference |
---|
- western blot; human; loading ...; fig 1a
| Koppula P, Olszewski K, Zhang Y, Kondiparthi L, Liu X, Lei G, et al. KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition. iScience. 2021;24:102649 pubmed publisher
|
- western blot; human; loading ...; fig 4b
| Bruckmann C, Tamburri S, De Lorenzi V, Doti N, Monti A, Mathiasen L, et al. Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis. Sci Rep. 2020;10:16809 pubmed publisher
|
- immunocytochemistry; Xenopus laevis; 1:100; loading ...; fig 1s2b
| Chan Z, Kwan H, Wong Y, Jiang Z, Zhou Z, Tam K, et al. Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs. elife. 2020;9: pubmed publisher
|
- immunocytochemistry; rat; 1:2000; loading ...; fig 3b
| Zhang M, Du W, Acklin S, Jin S, Xia F. SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair. J Clin Invest. 2020;130:2953-2965 pubmed publisher
|
- immunocytochemistry; human; 1:100; fig 4a
- western blot; human; 1:1000; fig 4b
| Wu Y, Jhao Y, Cheng Y, Chen Y. 15-Deoxy-?12,14-prostaglandin J2 inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction. Oncol Lett. 2017;13:2569-2576 pubmed publisher
|
- western blot; human; loading ...; fig 7b
| Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
|
- western blot; human; loading ...; fig 6a
| Tam K, Dalal K, Hsing M, Cheng C, Khosravi S, Yenki P, et al. Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner. Oncotarget. 2017;8:9617-9633 pubmed publisher
|
- western blot; human; loading ...; fig s4e
| Retallack H, Di Lullo E, Arias C, Knopp K, Laurie M, Sandoval Espinosa C, et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016;113:14408-14413 pubmed
|
- western blot; mouse; loading ...; fig s5c
| Gómez Salinero J, López Olañeta M, Ortiz Sánchez P, Larrasa Alonso J, Gatto A, Felkin L, et al. The Calcineurin Variant CnA?1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation. Cell Chem Biol. 2016;23:1372-1382 pubmed publisher
|
- western blot; human; loading ...; fig 2a, 2g
| Ladd B, Mazzola A, Bihani T, Lai Z, BRADFORD J, Collins M, et al. Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations. Oncotarget. 2016;7:54120-54136 pubmed publisher
|
- western blot; human; loading ...; fig s3d
| Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, et al. Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Cell Discov. 2016;2:15044 pubmed publisher
|
- western blot; human; fig 5
| Helmke C, Raab M, Rodel F, Matthess Y, Oellerich T, Mandal R, et al. Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8. Cell Res. 2016;26:914-34 pubmed publisher
|
- immunocytochemistry; human; 1:100; fig 4
- western blot; human; 1:2000; fig s1
| Freeman S, Christian S, Austin P, Iu I, Graves M, Huang L, et al. Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor. J Cell Sci. 2017;130:152-163 pubmed publisher
|
- western blot; human; fig 1
| Al Nakouzi N, Wang C, Beraldi E, Jäger W, Ettinger S, Fazli L, et al. Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis. EMBO Mol Med. 2016;8:761-78 pubmed publisher
|
- immunocytochemistry; human; loading ...; fig 2c
- western blot; human; loading ...; fig 2d
| SILVA P, Mendoza P, Rivas S, Diaz J, Moraga C, Quest A, et al. Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis. Oncotarget. 2016;7:29548-62 pubmed publisher
|
- western blot; mouse; 1:5000; loading ...; fig s2b
| Nader G, Ezratty E, Gundersen G. FAK, talin and PIPKI? regulate endocytosed integrin activation to polarize focal adhesion assembly. Nat Cell Biol. 2016;18:491-503 pubmed publisher
|
- immunocytochemistry; mouse; fig 5
| Rooney N, Wang P, Brennan K, Gilmore A, Streuli C. The Integrin-Mediated ILK-Parvin-?Pix Signaling Axis Controls Differentiation in Mammary Epithelial Cells. J Cell Physiol. 2016;231:2408-17 pubmed publisher
|
- western blot; human; 1:5000
| Liu X, Xiao Z, Han L, Zhang J, Lee S, Wang W, et al. LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nat Cell Biol. 2016;18:431-42 pubmed publisher
|
- western blot; mouse; 1:50,000; fig 4a
| Lee H, Dai F, Zhuang L, Xiao Z, Kim J, Zhang Y, et al. BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21. Oncotarget. 2016;7:19134-46 pubmed publisher
|
- western blot; human; fig 7
- western blot; pigs ; fig 2
| Tran Q, Firkins R, Giles J, Francis S, Matnishian V, Tran P, et al. Estrogen Enhances Linkage in the Vascular Endothelial Calmodulin Network via a Feedforward Mechanism at the G Protein-coupled Estrogen Receptor 1. J Biol Chem. 2016;291:10805-23 pubmed publisher
|
- immunohistochemistry - paraffin section; human; 1:400; fig 4
| McCabe M, Tarulli G, Laven Law G, Matthiesson K, Meachem S, McLachlan R, et al. Gonadotropin suppression in men leads to a reduction in claudin-11 at the Sertoli cell tight junction. Hum Reprod. 2016;31:875-86 pubmed publisher
|
- immunocytochemistry; mouse; loading ...; fig 4f
| Malinova D, Fritzsche M, Nowosad C, Armer H, Munro P, Blundell M, et al. WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts. J Leukoc Biol. 2016;99:699-710 pubmed publisher
|
- immunocytochemistry; mouse; fig 5a
| Hadzic E, Catillon M, Halavatyi A, Medves S, Van Troys M, Moes M, et al. Delineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption. PLoS ONE. 2015;10:e0140511 pubmed publisher
|
- western blot; human; 1:1000
| Case L, Baird M, Shtengel G, Campbell S, Hess H, Davidson M, et al. Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions. Nat Cell Biol. 2015;17:880-92 pubmed publisher
|
| Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y. The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation. PLoS ONE. 2015;10:e0124259 pubmed publisher
|
- immunocytochemistry; human; 1:100; fig 4
| Kim S, Wen W, Prowse P, Hamilton D. Regulation of matrix remodelling phenotype in gingival fibroblasts by substratum topography. J Cell Mol Med. 2015;19:1183-96 pubmed publisher
|
- immunocytochemistry; human; 1:200
| Toh Y, Xing J, Yu H. Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation. Biomaterials. 2015;50:87-97 pubmed publisher
|
| Fang F, Sun S, Wang L, Guan J, Giovannini M, Zhu Y, et al. Neural Crest-Specific TSC1 Deletion in Mice Leads to Sclerotic Craniofacial Bone Lesion. J Bone Miner Res. 2015;30:1195-205 pubmed publisher
|
- immunocytochemistry; human
| Kalendová A, Kalasová I, Yamazaki S, Uličná L, Harata M, Hozak P. Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block. Histochem Cell Biol. 2014;142:139-52 pubmed publisher
|
- western blot; mouse; 1:1000; fig 8
| Zhang L, Chen X, Sharma P, Moon M, Sheftel A, Dawood F, et al. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nat Commun. 2014;5:3430 pubmed publisher
|
| Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher
|
- immunocytochemistry; human
| Chiang Y, Wang K, Fazli L, Qi R, Gleave M, Collins C, et al. GATA2 as a potential metastasis-driving gene in prostate cancer. Oncotarget. 2014;5:451-61 pubmed
|
- immunocytochemistry; human; fig 1
| Potthoff E, Franco D, D Alessandro V, Starck C, Falk V, Zambelli T, et al. Toward a rational design of surface textures promoting endothelialization. Nano Lett. 2014;14:1069-79 pubmed publisher
|
- western blot; rat; 1:5000
| Liu F, Wang X, Hu G, Wang Y, Zhou J. The transcription factor TEAD1 represses smooth muscle-specific gene expression by abolishing myocardin function. J Biol Chem. 2014;289:3308-16 pubmed publisher
|
- immunohistochemistry - paraffin section; human; 1:100
| Smith Callahan L, Policastro G, Bernard S, Childers E, Boettcher R, Becker M. Influence of discrete and continuous culture conditions on human mesenchymal stem cell lineage choice in RGD concentration gradient hydrogels. Biomacromolecules. 2013;14:3047-54 pubmed publisher
|
| Schneider L, d Adda di Fagagna F. Neural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation. Nucleic Acids Res. 2012;40:5332-42 pubmed publisher
|
| Liu J, Yao Q, Xie X, Cui Q, Jiang T, Zhao Z, et al. Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARγ-Dependent Mechanism. Nutrients. 2022;14: pubmed publisher
|
| Xue Y, Morris J, Yang K, Fu Z, Zhu X, Johnson F, et al. SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria. Nat Commun. 2021;12:5404 pubmed publisher
|
| Jiang Q, Zheng N, Bu L, Zhang X, Zhang X, Wu Y, et al. SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions. Mol Cancer. 2021;20:100 pubmed publisher
|
| Vaughan H, Zamboni C, Radant N, Bhardwaj P, Revai Lechtich E, Hassan L, et al. Poly(beta-amino ester) nanoparticles enable tumor-specific TRAIL secretion and a bystander effect to treat liver cancer. Mol Ther Oncolytics. 2021;21:377-388 pubmed publisher
|
| Hao J, Ci X, Wang Y, Choi S, Sullivan S, Xue H, et al. GRB10 sustains AR activity by interacting with PP2A in prostate cancer cells. Int J Cancer. 2021;148:469-480 pubmed publisher
|
| Tishchenko A, Azorín D, Vidal Brime L, Muñoz M, Arenas P, Pearce C, et al. Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher
|
| Sá Pessoa J, Przybyszewska K, Vasconcelos F, Dumigan A, Frank C, Hobley L, et al. Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses. MBio. 2020;11: pubmed publisher
|
| Zecchin D, Moore C, Michailidis F, Horswell S, Rana S, Howell M, et al. Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer. EMBO Mol Med. 2020;12:e11987 pubmed publisher
|
| Hoxha S, Shepard A, Troutman S, Diao H, Doherty J, Janiszewska M, et al. YAP-Mediated Recruitment of YY1 and EZH2 Represses Transcription of Key Cell-Cycle Regulators. Cancer Res. 2020;80:2512-2522 pubmed publisher
|
| Morales Torres C, Wu M, Hobor S, Wainwright E, Martin M, Patel H, et al. Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis. Nat Commun. 2020;11:1792 pubmed publisher
|
| Liu J, Chen H, Ma L, He Z, Wang D, Liu Y, et al. Light-induced control of protein destruction by opto-PROTAC. Sci Adv. 2020;6:eaay5154 pubmed publisher
|
| Lei G, Zhang Y, Koppula P, Liu X, Zhang J, Lin S, et al. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Res. 2020;30:146-162 pubmed publisher
|
| Liu G, Byrd A, Warner A, Pei F, Basha E, Buchanan A, et al. Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover. Mol Cell Biol. 2020;40: pubmed publisher
|
| Herhaus L, Bhaskara R, Lystad A, Gestal Mato U, Covarrubias Pinto A, Bonn F, et al. TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease. EMBO Rep. 2020;21:e48317 pubmed publisher
|
| Fehling S, Miller A, Garcia P, Vance R, Yoon K. The combination of BET and PARP inhibitors is synergistic in models of cholangiocarcinoma. Cancer Lett. 2020;468:48-58 pubmed publisher
|
| Liu J, Yao Q, Xiao L, Ma W, Li F, Lai B, et al. PPARγ induces NEDD4 gene expression to promote autophagy and insulin action. FEBS J. 2020;287:529-545 pubmed publisher
|
| Hart P, Kenny H, Grassl N, Watters K, Litchfield L, Coscia F, et al. Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk. Cell Rep. 2019;29:4086-4098.e6 pubmed publisher
|
| Farrar C, Rouin G, Miller B, Raeman C, Mooney N, Hocking D. A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived Growth Factor-Induced Intracellular Calcium Release. Cells. 2019;8: pubmed publisher
|
| Matre P, Mu X, Wu J, Danila D, Hall M, Kolonin M, et al. CRISPR/Cas9-Based Dystrophin Restoration Reveals a Novel Role for Dystrophin in Bioenergetics and Stress Resistance of Muscle Progenitors. Stem Cells. 2019;37:1615-1628 pubmed publisher
|
| Holdgaard S, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen J, et al. Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nat Commun. 2019;10:4176 pubmed publisher
|
| Gurrapu S, Franzolin G, Fard D, Accardo M, Medico E, Sarotto I, et al. Reverse signaling by semaphorin 4C elicits SMAD1/5- and ID1/3-dependent invasive reprogramming in cancer cells. Sci Signal. 2019;12: pubmed publisher
|
| Martínez García D, Pérez Hernández M, Korrodi Gregório L, Quesada R, Ramos R, Baixeras N, et al. The Natural-Based Antitumor Compound T21 Decreases Survivin Levels through Potent STAT3 Inhibition in Lung Cancer Models. Biomolecules. 2019;9: pubmed publisher
|
| Konishi S, Yano T, Tanaka H, Mizuno T, Kanoh H, Tsukita K, et al. Vinculin is critical for the robustness of the epithelial cell sheet paracellular barrier for ions. Life Sci Alliance. 2019;2: pubmed publisher
|
| Thomas N, Choi H, Wei X, Wang L, Mishina Y, Guan J, et al. Autophagy Regulates Craniofacial Bone Acquisition. Calcif Tissue Int. 2019;: pubmed publisher
|
| Kawakami Y, Hambright W, Takayama K, Mu X, Lu A, Cummins J, et al. Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice. Mol Ther Methods Clin Dev. 2019;14:64-76 pubmed publisher
|
| Borghesan M, Fafián Labora J, Eleftheriadou O, Carpintero Fernández P, Pàez Ribes M, Vizcay Barrena G, et al. Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. Cell Rep. 2019;27:3956-3971.e6 pubmed publisher
|
| Wen T, Liu J, He X, Dong K, Hu G, Yu L, et al. Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation. Cell Death Differ. 2019;: pubmed publisher
|
| Raven P, Lysakowski S, Tan Z, D Costa N, Moskalev I, Frees S, et al. Inhibition of GLI2 with antisense-oligonucleotides: A potential therapy for the treatment of bladder cancer. J Cell Physiol. 2019;234:20634-20647 pubmed publisher
|
| Tomás Loba A, Manieri E, González Terán B, Mora A, Leiva Vega L, Santamans A, et al. p38γ is essential for cell cycle progression and liver tumorigenesis. Nature. 2019;568:557-560 pubmed publisher
|
| Manieri E, Herrera Melle L, Mora A, Tomás Loba A, Leiva Vega L, Fernández D, et al. Adiponectin accounts for gender differences in hepatocellular carcinoma incidence. J Exp Med. 2019;216:1108-1119 pubmed publisher
|
| Zhang Y, Koppula P, Gan B. Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1. Cell Cycle. 2019;18:773-783 pubmed publisher
|
| Falero Perez J, Sorenson C, Sheibani N. Cyp1b1-deficient retinal astrocytes are more proliferative and migratory and are protected from oxidative stress and inflammation. Am J Physiol Cell Physiol. 2019;316:C767-C781 pubmed publisher
|
| Lapointe F, Turcotte S, Veronneau S, Rola Pleszczynski M, Stankova J. Role of Protein Tyrosine Phosphatase Epsilon (PTPε) in Leukotriene D4-Induced CXCL8 Expression. J Pharmacol Exp Ther. 2019;369:270-281 pubmed publisher
|
| Oury J, Liu Y, Topf A, Todorovic S, Hoedt E, Preethish Kumar V, et al. MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses. J Cell Biol. 2019;218:1686-1705 pubmed publisher
|
| Liu Y, Fu Y, Wang Q, Li M, Zhou Z, Dabbagh D, et al. Proteomic profiling of HIV-1 infection of human CD4+ T cells identifies PSGL-1 as an HIV restriction factor. Nat Microbiol. 2019;4:813-825 pubmed publisher
|
| Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, et al. SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Dev Cell. 2019;48:329-344.e5 pubmed publisher
|
| Domke L, Franke W. The cell-cell junctions of mammalian testes: II. The lamellar smooth muscle monolayer cells of the peritubular wall are laterally connected by vertical adherens junctions-a novel architectonic cell-cell junction system. Cell Tissue Res. 2019;375:451-482 pubmed publisher
|
| Fang F, VanCleave A, Helmuth R, Torres H, Rickel K, Wollenzien H, et al. Targeting the Wnt/β-catenin pathway in human osteosarcoma cells. Oncotarget. 2018;9:36780-36792 pubmed publisher
|
| Lee C, Munuganti R, Peacock J, Dalal K, Jiao I, Shepherd A, et al. Targeting Semaphorin 3C in Prostate Cancer With Small Molecules. J Endocr Soc. 2018;2:1381-1394 pubmed publisher
|
| Falero Perez J, Song Y, Zhao Y, Teixeira L, Sorenson C, Sheibani N. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. PLoS ONE. 2018;13:e0206756 pubmed publisher
|
| Chauhan A, Liu X, Jing J, Lee H, Yadav R, Liu J, et al. STIM2 interacts with AMPK and regulates calcium-induced AMPK activation. FASEB J. 2018;:fj201801225R pubmed publisher
|
| Farrar C, Hocking D. Assembly of fibronectin fibrils selectively attenuates platelet-derived growth factor-induced intracellular calcium release in fibroblasts. J Biol Chem. 2018;293:18655-18666 pubmed publisher
|
| Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018;20:1181-1192 pubmed publisher
|
| de Jong S, Crequer A, Matos I, Hum D, Gunasekharan V, Lorenzo L, et al. The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses. J Exp Med. 2018;215:2289-2310 pubmed publisher
|
| Robotti F, Bottan S, Fraschetti F, Mallone A, Pellegrini G, Lindenblatt N, et al. A micron-scale surface topography design reducing cell adhesion to implanted materials. Sci Rep. 2018;8:10887 pubmed publisher
|
| Cappella M, Perfetti A, Cardinali B, Garcia Manteiga J, Carrara M, Provenzano C, et al. High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2. Cell Death Dis. 2018;9:729 pubmed publisher
|
| Rizzolio S, Cagnoni G, Battistini C, Bonelli S, Isella C, Van Ginderachter J, et al. Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies. J Clin Invest. 2018;128:3976-3990 pubmed publisher
|
| Yeo S, Paul R, Haas M, Wang C, Guan J. Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer. Autophagy. 2018;14:1214-1225 pubmed publisher
|
| Choi H, Yuan H, Fang F, Wei X, Liu L, Li Q, et al. Tsc1 Regulates the Balance Between Osteoblast and Adipocyte Differentiation Through Autophagy/Notch1/β-Catenin Cascade. J Bone Miner Res. 2018;33:2021-2034 pubmed publisher
|
| Perrotta C, Cervia D, Di Renzo I, Moscheni C, Bassi M, Campana L, et al. Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition. Front Immunol. 2018;9:1186 pubmed publisher
|
| Hilfenhaus G, Nguyen D, Freshman J, Prajapati D, Ma F, Song D, et al. Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers. J Cell Biol. 2018;217:2813-2830 pubmed publisher
|
| Kota S, Hou S, Guerrant W, Madoux F, Troutman S, Fernandez Vega V, et al. A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype. Oncogene. 2018;37:4372-4384 pubmed publisher
|
| Robichaux J, Elamin Y, Tan Z, Carter B, Zhang S, Liu S, et al. Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer. Nat Med. 2018;24:638-646 pubmed publisher
|
| Janzen C, Lei M, Jeong I, Ganguly A, Sullivan P, Paharkova V, et al. Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction. PLoS ONE. 2018;13:e0193583 pubmed publisher
|
| Gurrapu S, Pupo E, Franzolin G, Lanzetti L, Tamagnone L. Sema4C/PlexinB2 signaling controls breast cancer cell growth, hormonal dependence and tumorigenic potential. Cell Death Differ. 2018;25:1259-1275 pubmed publisher
|
| Nguyen A, Nguyen T, Zhang J, Devireddy S, Zhou P, Karydas A, et al. Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proc Natl Acad Sci U S A. 2018;115:E2849-E2858 pubmed publisher
|
| Ci Y, Li X, Chen M, Zhong J, North B, Inuzuka H, et al. SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation. Protein Cell. 2018;9:879-889 pubmed publisher
|
| Liu X, Hayano S, Pan H, Inagaki M, Ninomiya Tsuji J, Sun H, et al. Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death. Genesis. 2018;56:e23093 pubmed publisher
|
| Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, et al. Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Mol Cell. 2018;69:279-291.e5 pubmed publisher
|
| Yan M, Qi H, Li J, Ye G, Shao Y, Li T, et al. Identification of SPOP related metabolic pathways in prostate cancer. Oncotarget. 2017;8:103032-103046 pubmed publisher
|
| Ingallina E, Sorrentino G, Bertolio R, Lisek K, Zannini A, Azzolin L, et al. Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis. Nat Cell Biol. 2018;20:28-35 pubmed publisher
|
| Kim J, Louhghalam A, Lee G, Schafer B, Wirtz D, Kim D. Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology. Nat Commun. 2017;8:2123 pubmed publisher
|
| Rizzolio S, Battistini C, Cagnoni G, Apicella M, Vella V, Giordano S, et al. Downregulating Neuropilin-2 Triggers a Novel Mechanism Enabling EGFR-Dependent Resistance to Oncogene-Targeted Therapies. Cancer Res. 2018;78:1058-1068 pubmed publisher
|
| Vassilev V, Platek A, Hiver S, Enomoto H, Takeichi M. Catenins Steer Cell Migration via Stabilization of Front-Rear Polarity. Dev Cell. 2017;43:463-479.e5 pubmed publisher
|
| Mendoza P, SILVA P, Diaz J, Arriagada C, Canales J, Cerda O, et al. Calpain2 mediates Rab5-driven focal adhesion disassembly and cell migration. Cell Adh Migr. 2018;12:185-194 pubmed publisher
|
| Dubois F, Alpha K, Turner C. Paxillin regulates cell polarization and anterograde vesicle trafficking during cell migration. Mol Biol Cell. 2017;28:3815-3831 pubmed publisher
|
| Pera M, Larrea D, Guardia Laguarta C, Montesinos J, Velasco K, Agrawal R, et al. Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease. EMBO J. 2017;36:3356-3371 pubmed publisher
|
| Wei H, Cui R, Bahr J, Zanesi N, Luo Z, Meng W, et al. miR-130a Deregulates PTEN and Stimulates Tumor Growth. Cancer Res. 2017;77:6168-6178 pubmed publisher
|
| Liao Z, Kasirer Friede A, Shattil S. Optogenetic interrogation of integrin αVβ3 function in endothelial cells. J Cell Sci. 2017;130:3532-3541 pubmed publisher
|
| Falero Perez J, Park S, Sorenson C, Sheibani N. PEDF expression affects retinal endothelial cell proangiogenic properties through alterations in cell adhesive mechanisms. Am J Physiol Cell Physiol. 2017;313:C405-C420 pubmed publisher
|
| Korpal M, Puyang X, Jeremy Wu Z, Seiler R, Furman C, Oo H, et al. Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer. Nat Commun. 2017;8:103 pubmed publisher
|
| Piotrowska I, Isalan M, Mielcarek M. Early transcriptional alteration of histone deacetylases in a murine model of doxorubicin-induced cardiomyopathy. PLoS ONE. 2017;12:e0180571 pubmed publisher
|
| Pan H, Zhang H, Abraham P, Komatsu Y, Lyons K, Kaartinen V, et al. BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development. Dev Biol. 2017;429:260-270 pubmed publisher
|
| Koppula P, Zhang Y, Shi J, Li W, Gan B. The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate. J Biol Chem. 2017;292:14240-14249 pubmed publisher
|
| Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed publisher
|
| Vasconcelos Dos Santos A, Loponte H, Mantuano N, Oliveira I, de Paula I, Teixeira L, et al. Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway. Oncogenesis. 2017;6:e306 pubmed publisher
|
| Doiron K, Goyon V, Coyaud E, Rajapakse S, Raught B, McBride H. The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity. Sci Rep. 2017;7:107 pubmed publisher
|
| Jangi M, Fleet C, Cullen P, Gupta S, Mekhoubad S, Chiao E, et al. SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage. Proc Natl Acad Sci U S A. 2017;114:E2347-E2356 pubmed publisher
|
| Liu X, Chen M, Li L, Gong L, Zhou H, Gao D. Extracellular Signal-regulated Kinases (ERKs) Phosphorylate Lin28a Protein to Modulate P19 Cell Proliferation and Differentiation. J Biol Chem. 2017;292:3970-3976 pubmed publisher
|
| Mutz C, Schwentner R, Aryee D, Bouchard E, Mejia E, Hatch G, et al. EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells. Oncotarget. 2017;8:24679-24693 pubmed publisher
|
| Sorrentino G, Ruggeri N, Zannini A, Ingallina E, Bertolio R, Marotta C, et al. Glucocorticoid receptor signalling activates YAP in breast cancer. Nat Commun. 2017;8:14073 pubmed publisher
|
| Zhang L, Peng S, Dai X, Gan W, Nie X, Wei W, et al. Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells. Cancer Lett. 2017;390:11-20 pubmed publisher
|
| Thakar K, May C, Rogers A, Carroll C. Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA. Mol Biol Cell. 2017;28:182-191 pubmed publisher
|
| Bhogaraju S, Kalayil S, Liu Y, Bonn F, Colby T, Matic I, et al. Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination. Cell. 2016;167:1636-1649.e13 pubmed publisher
|
| Prudent J, Popgeorgiev N, Gadet R, Deygas M, Rimokh R, Gillet G. Mitochondrial Ca2+ uptake controls actin cytoskeleton dynamics during cell migration. Sci Rep. 2016;6:36570 pubmed publisher
|
| Liu X, Gan B. lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1. Cell Cycle. 2016;15:3471-3481 pubmed publisher
|
| Lamason R, Bastounis E, Kafai N, Serrano R, Del Alamo J, Theriot J, et al. Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread. Cell. 2016;167:670-683.e10 pubmed publisher
|
| Baruffaldi F, Montarras D, Basile V, De Feo L, Badodi S, Ganassi M, et al. Dynamic Phosphorylation of the Myocyte Enhancer Factor 2Cα1 Splice Variant Promotes Skeletal Muscle Regeneration and Hypertrophy. Stem Cells. 2017;35:725-738 pubmed publisher
|
| Yun S, Budatha M, Dahlman J, Coon B, Cameron R, Langer R, et al. Interaction between integrin ?5 and PDE4D regulates endothelial inflammatory signalling. Nat Cell Biol. 2016;18:1043-53 pubmed publisher
|
| Bryan C, Chien C, Kwan K. Loss of laminin alpha 1 results in multiple structural defects and divergent effects on adhesion during vertebrate optic cup morphogenesis. Dev Biol. 2016;416:324-37 pubmed publisher
|
| Lenti E, Farinello D, Yokoyama K, Penkov D, Castagnaro L, Lavorgna G, et al. Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development. J Clin Invest. 2016;126:2452-64 pubmed publisher
|
| Yeo S, Wen J, Chen S, Guan J. Autophagy Differentially Regulates Distinct Breast Cancer Stem-like Cells in Murine Models via EGFR/Stat3 and Tgf?/Smad Signaling. Cancer Res. 2016;76:3397-410 pubmed publisher
|
| Likhitpanichkul M, Torre O, Gruen J, Walter B, Hecht A, Iatridis J. Do mechanical strain and TNF-α interact to amplify pro-inflammatory cytokine production in human annulus fibrosus cells?. J Biomech. 2016;49:1214-1220 pubmed publisher
|
| Elong Edimo W, Ghosh S, Derua R, Janssens V, Waelkens E, Vanderwinden J, et al. SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells. J Cell Sci. 2016;129:1101-14 pubmed publisher
|
| Xu M, Gonzalez Hurtado E, Martinez E. Core promoter-specific gene regulation: TATA box selectivity and Initiator-dependent bi-directionality of serum response factor-activated transcription. Biochim Biophys Acta. 2016;1859:553-63 pubmed publisher
|
| Xu L, Rönnlund D, Aspenstrom P, Braun L, Gad A, Widengren J. Resolution, target density and labeling effects in colocalization studies - suppression of false positives by nanoscopy and modified algorithms. FEBS J. 2016;283:882-98 pubmed publisher
|
| Pucker A, Jackson A, Morris H, Fischer A, McHugh K, Mutti D. Ciliary Muscle Cell Changes During Guinea Pig Development. Invest Ophthalmol Vis Sci. 2015;56:7691-6 pubmed publisher
|
| Yu Q, Sun H, Chen W, Chen X, Xu Y, He Y, et al. Sex-specific association of rs4746172 of VCL gene with hypertension in two Han populations from Southern China. Sci Rep. 2015;5:15245 pubmed publisher
|
| Xu F, Ahmed A, Kang X, Hu G, Liu F, Zhang W, et al. MicroRNA-15b/16 Attenuates Vascular Neointima Formation by Promoting the Contractile Phenotype of Vascular Smooth Muscle Through Targeting YAP. Arterioscler Thromb Vasc Biol. 2015;35:2145-52 pubmed publisher
|
| van der Ent W, Burrello C, Teunisse A, Ksander B, van der Velden P, Jager M, et al. Modeling of human uveal melanoma in zebrafish xenograft embryos. Invest Ophthalmol Vis Sci. 2014;55:6612-22 pubmed publisher
|
| Rubashkin M, Cassereau L, Bainer R, DuFort C, Yui Y, Ou G, et al. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res. 2014;74:4597-611 pubmed publisher
|
| Galletti M, Cantoni S, Zambelli F, Valente S, Palazzini M, Manes A, et al. Dissecting histone deacetylase role in pulmonary arterial smooth muscle cell proliferation and migration. Biochem Pharmacol. 2014;91:181-90 pubmed publisher
|
| Brack S, Attinger Toller I, Schade B, Mourlane F, Klupsch K, Woods R, et al. A bispecific HER2-targeting FynomAb with superior antitumor activity and novel mode of action. Mol Cancer Ther. 2014;13:2030-9 pubmed publisher
|
| van der Ent W, Jochemsen A, Teunisse A, Krens S, Szuhai K, Spaink H, et al. Ewing sarcoma inhibition by disruption of EWSR1-FLI1 transcriptional activity and reactivation of p53. J Pathol. 2014;233:415-24 pubmed publisher
|
| Pattabiraman P, Epstein D, Rao P. Regulation of Adherens Junctions in Trabecular Meshwork Cells by Rac GTPase and their influence on Intraocular Pressure. J Ocul Biol. 2013;1: pubmed
|
| Wei H, Wang C, Croce C, Guan J. p62/SQSTM1 synergizes with autophagy for tumor growth in vivo. Genes Dev. 2014;28:1204-16 pubmed publisher
|
| Jung K, Wu F, Wang P, Ye X, Abdulkarim B, Lai R. YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells. BMC Cancer. 2014;14:328 pubmed publisher
|
| Bendris N, Cheung C, Leong H, Lewis J, Chambers A, Blanchard J, et al. Cyclin A2, a novel regulator of EMT. Cell Mol Life Sci. 2014;71:4881-94 pubmed publisher
|
| Ganassi M, Badodi S, Polacchini A, Baruffaldi F, Battini R, Hughes S, et al. Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb. Biochim Biophys Acta. 2014;1839:559-70 pubmed publisher
|
| Knight D, Gillies E, Mequanint K. Biomimetic L-aspartic acid-derived functional poly(ester amide)s for vascular tissue engineering. Acta Biomater. 2014;10:3484-96 pubmed publisher
|
| Saxena S, Spears M, Yoshida H, Gaulding J, Garcia A, Lyon L. Microgel film dynamics modulate cell adhesion behavior. Soft Matter. 2014;10:1356-64 pubmed
|
| Schneider L. Survival of neural stem cells undergoing DNA damage-induced astrocytic differentiation in self-renewal-promoting conditions in vitro. PLoS ONE. 2014;9:e87228 pubmed publisher
|
| Chen M, Zhang W, Lu X, Hoggatt A, Gunst S, Kassab G, et al. Regulation of 130-kDa smooth muscle myosin light chain kinase expression by an intronic CArG element. J Biol Chem. 2013;288:34647-57 pubmed publisher
|
| Ferranti F, D Anselmi F, Caruso M, Lei V, Dinicola S, Pasqualato A, et al. TCam-2 seminoma cells exposed to egg-derived microenvironment modify their shape, adhesive pattern and migratory behaviour: a molecular and morphometric analysis. PLoS ONE. 2013;8:e76192 pubmed publisher
|
| Wang R, Bi J, Ampah K, Ba X, Liu W, Zeng X. Lipid rafts control human melanoma cell migration by regulating focal adhesion disassembly. Biochim Biophys Acta. 2013;1833:3195-3205 pubmed publisher
|
| Hu J, Ho A, Yuan L, Hu B, Hua S, Hwang S, et al. From the Cover: Neutralization of terminal differentiation in gliomagenesis. Proc Natl Acad Sci U S A. 2013;110:14520-7 pubmed publisher
|
| Mendoza P, Ortiz R, Diaz J, Quest A, Leyton L, Stupack D, et al. Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells. J Cell Sci. 2013;126:3835-47 pubmed publisher
|
| Graf R, Munschauer M, Mastrobuoni G, Mayr F, Heinemann U, Kempa S, et al. Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation. RNA Biol. 2013;10:1146-59 pubmed publisher
|
| Wickert L, Blanchette J, Waldschmidt N, Bertics P, Denu J, Denlinger L, et al. The C-terminus of human nucleotide receptor P2X7 is critical for receptor oligomerization and N-linked glycosylation. PLoS ONE. 2013;8:e63789 pubmed publisher
|
| Liu F, Fang F, Yuan H, Yang D, Chen Y, Williams L, et al. Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res. 2013;28:2414-30 pubmed publisher
|
| Saphirstein R, Gao Y, Jensen M, Gallant C, Vetterkind S, Moore J, et al. The focal adhesion: a regulated component of aortic stiffness. PLoS ONE. 2013;8:e62461 pubmed publisher
|
| Smith Callahan L, Childers E, Bernard S, Weiner S, Becker M. Maximizing phenotype constraint and extracellular matrix production in primary human chondrocytes using arginine-glycine-aspartate concentration gradient hydrogels. Acta Biomater. 2013;9:7420-8 pubmed publisher
|
| Tong L, Png E, Aihua H, Yong S, Yeo H, Riau A, et al. Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion. Biochim Biophys Acta. 2013;1833:1304-15 pubmed publisher
|
| Fröbel J, Cadeddu R, Hartwig S, Bruns I, Wilk C, Kundgen A, et al. Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes. Mol Cell Proteomics. 2013;12:1272-80 pubmed publisher
|
| Callahan L, Ganios A, Childers E, Weiner S, Becker M. Primary human chondrocyte extracellular matrix formation and phenotype maintenance using RGD-derivatized PEGDM hydrogels possessing a continuous Young's modulus gradient. Acta Biomater. 2013;9:6095-104 pubmed publisher
|
| Hoshino D, Jourquin J, Emmons S, Miller T, Goldgof M, Costello K, et al. Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKC? invasive signaling axis. Sci Signal. 2012;5:ra66 pubmed publisher
|
| Hartsock A, Nelson W. Competitive regulation of E-cadherin juxtamembrane domain degradation by p120-catenin binding and Hakai-mediated ubiquitination. PLoS ONE. 2012;7:e37476 pubmed publisher
|
| Zeiger A, Loe F, Li R, Raghunath M, Van Vliet K. Macromolecular crowding directs extracellular matrix organization and mesenchymal stem cell behavior. PLoS ONE. 2012;7:e37904 pubmed publisher
|
| Carlisle R, Heffernan A, Brimble E, Liu L, Jerome D, Collins C, et al. TDAG51 mediates epithelial-to-mesenchymal transition in human proximal tubular epithelium. Am J Physiol Renal Physiol. 2012;303:F467-81 pubmed publisher
|
| Jeanes A, Wang P, Moreno Layseca P, Paul N, Cheung J, Tsang R, et al. Specific ?-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells. J Biol Chem. 2012;287:24103-12 pubmed publisher
|
| Childers M, Bogan J, Bogan D, Greiner H, Holder M, Grange R, et al. Chronic administration of a leupeptin-derived calpain inhibitor fails to ameliorate severe muscle pathology in a canine model of duchenne muscular dystrophy. Front Pharmacol. 2011;2:89 pubmed publisher
|
| Huang G, Xie L, Linask K, Zhang C, Zhao X, Yang Y, et al. Evaluating the role of connexin43 in congenital heart disease: Screening for mutations in patients with outflow tract anomalies and the analysis of knock-in mouse models. J Cardiovasc Dis Res. 2011;2:206-12 pubmed publisher
|
| Fujita M, Mitsuhashi H, Isogai S, Nakata T, Kawakami A, Nonaka I, et al. Filamin C plays an essential role in the maintenance of the structural integrity of cardiac and skeletal muscles, revealed by the medaka mutant zacro. Dev Biol. 2012;361:79-89 pubmed publisher
|
| Zhang L, Widau R, Herring B, Gallagher P. Delta-like 1-Lysine613 regulates notch signaling. Biochim Biophys Acta. 2011;1813:2036-43 pubmed publisher
|
| Touw K, Chakraborty S, Zhang W, Obukhov A, Tune J, Gunst S, et al. Altered calcium signaling in colonic smooth muscle of type 1 diabetic mice. Am J Physiol Gastrointest Liver Physiol. 2012;302:G66-76 pubmed publisher
|
| Gutierrez A, Snyder E, Mariño Enríquez A, Zhang Y, Sioletic S, Kozakewich E, et al. Aberrant AKT activation drives well-differentiated liposarcoma. Proc Natl Acad Sci U S A. 2011;108:16386-91 pubmed publisher
|
| Paku S, Dezso K, Bugyik E, Tovari J, Timar J, Nagy P, et al. A new mechanism for pillar formation during tumor-induced intussusceptive angiogenesis: inverse sprouting. Am J Pathol. 2011;179:1573-85 pubmed publisher
|
| Francis J, Lin W, Rozenblatt Rosen O, Meyerson M. The menin tumor suppressor protein is phosphorylated in response to DNA damage. PLoS ONE. 2011;6:e16119 pubmed publisher
|
| Mariño Enríquez A, Ou W, Weldon C, Fletcher J, Perez Atayde A. ALK rearrangement in sickle cell trait-associated renal medullary carcinoma. Genes Chromosomes Cancer. 2011;50:146-53 pubmed publisher
|
| Call J, McKeehen J, Novotny S, Lowe D. Progressive resistance voluntary wheel running in the mdx mouse. Muscle Nerve. 2010;42:871-80 pubmed publisher
|
| Casazza A, Finisguerra V, Capparuccia L, Camperi A, Swiercz J, Rizzolio S, et al. Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice. J Clin Invest. 2010;120:2684-98 pubmed publisher
|
| Inoue T, Pecen P, Maddala R, Skiba N, Pattabiraman P, Epstein D, et al. Characterization of cytoskeleton-enriched protein fraction of the trabecular meshwork and ciliary muscle cells. Invest Ophthalmol Vis Sci. 2010;51:6461-71 pubmed publisher
|
| Henry S, Traver M, Daniell X, Indaram M, Oliver T, Taylor G. Regulation of macrophage motility by Irgm1. J Leukoc Biol. 2010;87:333-43 pubmed publisher
|
| LaGory E, Sitailo L, Denning M. The protein kinase Cdelta catalytic fragment is critical for maintenance of the G2/M DNA damage checkpoint. J Biol Chem. 2010;285:1879-87 pubmed publisher
|
| Gao D, Inuzuka H, Korenjak M, Tseng A, Wu T, Wan L, et al. Cdh1 regulates cell cycle through modulating the claspin/Chk1 and the Rb/E2F1 pathways. Mol Biol Cell. 2009;20:3305-16 pubmed publisher
|
| Michael K, Dumbauld D, Burns K, Hanks S, Garcia A. Focal adhesion kinase modulates cell adhesion strengthening via integrin activation. Mol Biol Cell. 2009;20:2508-19 pubmed publisher
|
| Jin L, Hastings N, Blackman B, Somlyo A. Mechanical properties of the extracellular matrix alter expression of smooth muscle protein LPP and its partner palladin; relationship to early atherosclerosis and vascular injury. J Muscle Res Cell Motil. 2009;30:41-55 pubmed publisher
|
| Finkbeiner M, Astanehe A, To K, Fotovati A, Davies A, Zhao Y, et al. Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells. Oncogene. 2009;28:1421-31 pubmed publisher
|
| Lee C, Dhillon J, Wang M, Gao Y, Hu K, Park E, et al. Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice. Cancer Res. 2008;68:8661-6 pubmed publisher
|
| Norris R, Freudzon M, Mehlmann L, Cowan A, Simon A, Paul D, et al. Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption. Development. 2008;135:3229-38 pubmed publisher
|
| Terzian T, Suh Y, Iwakuma T, Post S, Neumann M, Lang G, et al. The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss. Genes Dev. 2008;22:1337-44 pubmed publisher
|
| Gray M, van Buren G, Dallas N, Xia L, Wang X, Yang A, et al. Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver. J Natl Cancer Inst. 2008;100:109-20 pubmed publisher
|
| Klein R, Spofford L, Abel E, Ortiz A, Aplin A. B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization. Mol Biol Cell. 2008;19:498-508 pubmed
|
| Szczur K, Xu H, Atkinson S, Zheng Y, Filippi M. Rho GTPase CDC42 regulates directionality and random movement via distinct MAPK pathways in neutrophils. Blood. 2006;108:4205-13 pubmed
|
| Ziegler W, Liddington R, Critchley D. The structure and regulation of vinculin. Trends Cell Biol. 2006;16:453-60 pubmed
|
| Amagasaki K, Kaneto H, Heldin C, Lennartsson J. c-Jun N-terminal kinase is necessary for platelet-derived growth factor-mediated chemotaxis in primary fibroblasts. J Biol Chem. 2006;281:22173-9 pubmed
|
| Wu J, Lee C, Yokom D, Jiang H, Cheang M, Yorida E, et al. Disruption of the Y-box binding protein-1 results in suppression of the epidermal growth factor receptor and HER-2. Cancer Res. 2006;66:4872-9 pubmed
|
| Bennett P, Maggs A, Baines A, Pinder J. The transitional junction: a new functional subcellular domain at the intercalated disc. Mol Biol Cell. 2006;17:2091-100 pubmed
|
| Wu R, Xu Y, Ma Z, Nwariaku F, Sarosi G, Terada L. Subcellular targeting of oxidants during endothelial cell migration. J Cell Biol. 2005;171:893-904 pubmed
|
| Sukezane T, Oneyama C, Kakumoto K, Shibutani K, Hanafusa H, Akagi T. Human diploid fibroblasts are resistant to MEK/ERK-mediated disruption of the actin cytoskeleton and invasiveness stimulated by Ras. Oncogene. 2005;24:5648-55 pubmed
|
| Chen H, Cohen D, Choudhury D, Kioka N, Craig S. Spatial distribution and functional significance of activated vinculin in living cells. J Cell Biol. 2005;169:459-70 pubmed
|
| Crean J, Furlong F, Finlay D, Mitchell D, Murphy M, Conway B, et al. Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization. FASEB J. 2004;18:1541-3 pubmed
|
| Hilenski L, Clempus R, Quinn M, Lambeth J, Griendling K. Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2004;24:677-83 pubmed
|
| McKean D, Sisbarro L, Ilic D, Kaplan Alburquerque N, Nemenoff R, Weiser Evans M, et al. FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration. J Cell Biol. 2003;161:393-402 pubmed
|
| Beviglia L, Golubovskaya V, Xu L, Yang X, Craven R, Cance W. Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis. Biochem J. 2003;373:201-10 pubmed
|
| Nicholas B, Smethurst P, Verderio E, Jones R, Griffin M. Cross-linking of cellular proteins by tissue transglutaminase during necrotic cell death: a mechanism for maintaining tissue integrity. Biochem J. 2003;371:413-22 pubmed
|
| Austin R, Fox J, Werstuck G, Stafford A, Bulman D, Dally G, et al. Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion. J Biol Chem. 2002;277:47106-13 pubmed
|
| Crean J, Finlay D, Murphy M, Moss C, Godson C, Martin F, et al. The role of p42/44 MAPK and protein kinase B in connective tissue growth factor induced extracellular matrix protein production, cell migration, and actin cytoskeletal rearrangement in human mesangial cells. J Biol Chem. 2002;277:44187-94 pubmed
|
| Bouzahzah B, Albanese C, Ahmed F, Pixley F, Lisanti M, Segall J, et al. Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways. Mol Med. 2001;7:816-30 pubmed
|
| West K, Zhang H, Brown M, Nikolopoulos S, Riedy M, Horwitz A, et al. The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL). J Cell Biol. 2001;154:161-76 pubmed
|
| Crewe J, Armitage W. Integrity of epithelium and endothelium in organ-cultured human corneas. Invest Ophthalmol Vis Sci. 2001;42:1757-61 pubmed
|
| Laukaitis C, Webb D, Donais K, Horwitz A. Differential dynamics of alpha 5 integrin, paxillin, and alpha-actinin during formation and disassembly of adhesions in migrating cells. J Cell Biol. 2001;153:1427-40 pubmed
|
| D Addario M, Arora P, Fan J, Ganss B, Ellen R, McCulloch C. Cytoprotection against mechanical forces delivered through beta 1 integrins requires induction of filamin A. J Biol Chem. 2001;276:31969-77 pubmed
|
| Adams J, Kureishy N, Taylor A. A role for syndecan-1 in coupling fascin spike formation by thrombospondin-1. J Cell Biol. 2001;152:1169-82 pubmed
|
| Kjøller L, Hall A. Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin. J Cell Biol. 2001;152:1145-57 pubmed
|
| Yvon A, Wadsworth P. Region-specific microtubule transport in motile cells. J Cell Biol. 2000;151:1003-12 pubmed
|
| Greenwood J, Theibert A, Prestwich G, Murphy Ullrich J. Restructuring of focal adhesion plaques by PI 3-kinase. Regulation by PtdIns (3,4,5)-p(3) binding to alpha-actinin. J Cell Biol. 2000;150:627-42 pubmed
|
| Giannini A, Vivanco M, Kypta R. alpha-catenin inhibits beta-catenin signaling by preventing formation of a beta-catenin*T-cell factor*DNA complex. J Biol Chem. 2000;275:21883-8 pubmed
|
| Thoreson M, Anastasiadis P, Daniel J, Ireton R, Wheelock M, Johnson K, et al. Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion. J Cell Biol. 2000;148:189-202 pubmed
|
| Ishida T, Ishida M, Suero J, Takahashi M, Berk B. Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src. J Clin Invest. 1999;103:789-97 pubmed
|
| Trusolino L, Serini G, Cecchini G, Besati C, Ambesi Impiombato F, Marchisio P, et al. Growth factor-dependent activation of alphavbeta3 integrin in normal epithelial cells: implications for tumor invasion. J Cell Biol. 1998;142:1145-56 pubmed
|
| Xu W, Coll J, Adamson E. Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells; effects on cell locomotion by domain deleted vinculin. J Cell Sci. 1998;111 ( Pt 11):1535-44 pubmed
|
| Rocnik E, Chan B, Pickering J. Evidence for a role of collagen synthesis in arterial smooth muscle cell migration. J Clin Invest. 1998;101:1889-98 pubmed
|
| Pelham R, Wang Y. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci U S A. 1997;94:13661-5 pubmed
|
| Machesky L, Hall A. Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization. J Cell Biol. 1997;138:913-26 pubmed
|
| De Rycke J, Comtet E, Chalareng C, Boury M, Tasca C, Milon A. Enteropathogenic Escherichia coli O103 from rabbit elicits actin stress fibers and focal adhesions in HeLa epithelial cells, cytopathic effects that are linked to an analog of the locus of enterocyte effacement. Infect Immun. 1997;65:2555-63 pubmed
|
| Yang J, Hynes R. Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins. Mol Biol Cell. 1996;7:1737-48 pubmed
|
| Silletti S, Paku S, Raz A. Tumor autocrine motility factor responses are mediated through cell contact and focal adhesion rearrangement in the absence of new tyrosine phosphorylation in metastatic cells. Am J Pathol. 1996;148:1649-60 pubmed
|
| Moiseyeva E, Weller P, Zhidkova N, Corben E, Patel B, Jasinska I, et al. Organization of the human gene encoding the cytoskeletal protein vinculin and the sequence of the vinculin promoter. J Biol Chem. 1993;268:4318-25 pubmed
|
| Knudsen K, Soler A, Johnson K, Wheelock M. Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. J Cell Biol. 1995;130:67-77 pubmed
|
| Castellani L, Reedy M, Gauzzi M, Provenzano C, Alema S, Falcone G. Maintenance of the differentiated state in skeletal muscle: activation of v-Src disrupts sarcomeres in quail myotubes. J Cell Biol. 1995;130:871-85 pubmed
|
| Volberg T, Geiger B, Kartenbeck J, Franke W. Changes in membrane-microfilament interaction in intercellular adherens junctions upon removal of extracellular Ca2+ ions. J Cell Biol. 1986;102:1832-42 pubmed
|
| Mulligan L, Gardner E, Telenius H, Ponder B. Complementary physical and genetic techniques map the vinculin (VCL) gene on chromosome 10q. Genomics. 1992;13:1347-9 pubmed
|