product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Vinculin antibody produced in mouse
catalog :
V4505
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VIN-11-5
reactivity :
human, mouse, rat, chicken, bovine, pigs , zebrafish , Xenopus laevis
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 229
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1a
Koppula P, Olszewski K, Zhang Y, Kondiparthi L, Liu X, Lei G, et al. KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition. iScience. 2021;24:102649 pubmed publisher
  • western blot; human; loading ...; fig 4b
Bruckmann C, Tamburri S, De Lorenzi V, Doti N, Monti A, Mathiasen L, et al. Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis. Sci Rep. 2020;10:16809 pubmed publisher
  • immunocytochemistry; Xenopus laevis; 1:100; loading ...; fig 1s2b
Chan Z, Kwan H, Wong Y, Jiang Z, Zhou Z, Tam K, et al. Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs. elife. 2020;9: pubmed publisher
  • immunocytochemistry; rat; 1:2000; loading ...; fig 3b
Zhang M, Du W, Acklin S, Jin S, Xia F. SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair. J Clin Invest. 2020;130:2953-2965 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4a
  • western blot; human; 1:1000; fig 4b
Wu Y, Jhao Y, Cheng Y, Chen Y. 15-Deoxy-?12,14-prostaglandin J2 inhibits migration of human thyroid carcinoma cells by disrupting focal adhesion complex and adherens junction. Oncol Lett. 2017;13:2569-2576 pubmed publisher
  • western blot; human; loading ...; fig 7b
Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
  • western blot; human; loading ...; fig 6a
Tam K, Dalal K, Hsing M, Cheng C, Khosravi S, Yenki P, et al. Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner. Oncotarget. 2017;8:9617-9633 pubmed publisher
  • western blot; human; loading ...; fig s4e
Retallack H, Di Lullo E, Arias C, Knopp K, Laurie M, Sandoval Espinosa C, et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016;113:14408-14413 pubmed
  • western blot; mouse; loading ...; fig s5c
Gómez Salinero J, López Olañeta M, Ortiz Sánchez P, Larrasa Alonso J, Gatto A, Felkin L, et al. The Calcineurin Variant CnA?1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation. Cell Chem Biol. 2016;23:1372-1382 pubmed publisher
  • western blot; human; loading ...; fig 2a, 2g
Ladd B, Mazzola A, Bihani T, Lai Z, BRADFORD J, Collins M, et al. Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations. Oncotarget. 2016;7:54120-54136 pubmed publisher
  • western blot; human; loading ...; fig s3d
Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, et al. Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Cell Discov. 2016;2:15044 pubmed publisher
  • western blot; human; fig 5
Helmke C, Raab M, Rodel F, Matthess Y, Oellerich T, Mandal R, et al. Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8. Cell Res. 2016;26:914-34 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
  • western blot; human; 1:2000; fig s1
Freeman S, Christian S, Austin P, Iu I, Graves M, Huang L, et al. Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor. J Cell Sci. 2017;130:152-163 pubmed publisher
  • western blot; human; fig 1
Al Nakouzi N, Wang C, Beraldi E, Jäger W, Ettinger S, Fazli L, et al. Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis. EMBO Mol Med. 2016;8:761-78 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 2d
SILVA P, Mendoza P, Rivas S, Diaz J, Moraga C, Quest A, et al. Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis. Oncotarget. 2016;7:29548-62 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig s2b
Nader G, Ezratty E, Gundersen G. FAK, talin and PIPKI? regulate endocytosed integrin activation to polarize focal adhesion assembly. Nat Cell Biol. 2016;18:491-503 pubmed publisher
  • immunocytochemistry; mouse; fig 5
Rooney N, Wang P, Brennan K, Gilmore A, Streuli C. The Integrin-Mediated ILK-Parvin-?Pix Signaling Axis Controls Differentiation in Mammary Epithelial Cells. J Cell Physiol. 2016;231:2408-17 pubmed publisher
  • western blot; human; 1:5000
Liu X, Xiao Z, Han L, Zhang J, Lee S, Wang W, et al. LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nat Cell Biol. 2016;18:431-42 pubmed publisher
  • western blot; mouse; 1:50,000; fig 4a
Lee H, Dai F, Zhuang L, Xiao Z, Kim J, Zhang Y, et al. BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21. Oncotarget. 2016;7:19134-46 pubmed publisher
  • western blot; human; fig 7
  • western blot; pigs ; fig 2
Tran Q, Firkins R, Giles J, Francis S, Matnishian V, Tran P, et al. Estrogen Enhances Linkage in the Vascular Endothelial Calmodulin Network via a Feedforward Mechanism at the G Protein-coupled Estrogen Receptor 1. J Biol Chem. 2016;291:10805-23 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:400; fig 4
McCabe M, Tarulli G, Laven Law G, Matthiesson K, Meachem S, McLachlan R, et al. Gonadotropin suppression in men leads to a reduction in claudin-11 at the Sertoli cell tight junction. Hum Reprod. 2016;31:875-86 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 4f
Malinova D, Fritzsche M, Nowosad C, Armer H, Munro P, Blundell M, et al. WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts. J Leukoc Biol. 2016;99:699-710 pubmed publisher
  • immunocytochemistry; mouse; fig 5a
Hadzic E, Catillon M, Halavatyi A, Medves S, Van Troys M, Moes M, et al. Delineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption. PLoS ONE. 2015;10:e0140511 pubmed publisher
  • western blot; human; 1:1000
Case L, Baird M, Shtengel G, Campbell S, Hess H, Davidson M, et al. Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions. Nat Cell Biol. 2015;17:880-92 pubmed publisher
  • western blot; human
Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y. The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation. PLoS ONE. 2015;10:e0124259 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 4
Kim S, Wen W, Prowse P, Hamilton D. Regulation of matrix remodelling phenotype in gingival fibroblasts by substratum topography. J Cell Mol Med. 2015;19:1183-96 pubmed publisher
  • immunocytochemistry; human; 1:200
Toh Y, Xing J, Yu H. Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation. Biomaterials. 2015;50:87-97 pubmed publisher
  • western blot; mouse
Fang F, Sun S, Wang L, Guan J, Giovannini M, Zhu Y, et al. Neural Crest-Specific TSC1 Deletion in Mice Leads to Sclerotic Craniofacial Bone Lesion. J Bone Miner Res. 2015;30:1195-205 pubmed publisher
  • immunocytochemistry; human
Kalendová A, Kalasová I, Yamazaki S, Uličná L, Harata M, Hozak P. Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block. Histochem Cell Biol. 2014;142:139-52 pubmed publisher
  • western blot; mouse; 1:1000; fig 8
Zhang L, Chen X, Sharma P, Moon M, Sheftel A, Dawood F, et al. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nat Commun. 2014;5:3430 pubmed publisher
  • western blot; human
Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher
  • immunocytochemistry; human
Chiang Y, Wang K, Fazli L, Qi R, Gleave M, Collins C, et al. GATA2 as a potential metastasis-driving gene in prostate cancer. Oncotarget. 2014;5:451-61 pubmed
  • immunocytochemistry; human; fig 1
Potthoff E, Franco D, D Alessandro V, Starck C, Falk V, Zambelli T, et al. Toward a rational design of surface textures promoting endothelialization. Nano Lett. 2014;14:1069-79 pubmed publisher
  • western blot; rat; 1:5000
Liu F, Wang X, Hu G, Wang Y, Zhou J. The transcription factor TEAD1 represses smooth muscle-specific gene expression by abolishing myocardin function. J Biol Chem. 2014;289:3308-16 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Smith Callahan L, Policastro G, Bernard S, Childers E, Boettcher R, Becker M. Influence of discrete and continuous culture conditions on human mesenchymal stem cell lineage choice in RGD concentration gradient hydrogels. Biomacromolecules. 2013;14:3047-54 pubmed publisher
  • western blot; zebrafish
Schneider L, d Adda di Fagagna F. Neural stem cells exposed to BrdU lose their global DNA methylation and undergo astrocytic differentiation. Nucleic Acids Res. 2012;40:5332-42 pubmed publisher
Liu J, Yao Q, Xie X, Cui Q, Jiang T, Zhao Z, et al. Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARγ-Dependent Mechanism. Nutrients. 2022;14: pubmed publisher
Xue Y, Morris J, Yang K, Fu Z, Zhu X, Johnson F, et al. SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria. Nat Commun. 2021;12:5404 pubmed publisher
Jiang Q, Zheng N, Bu L, Zhang X, Zhang X, Wu Y, et al. SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions. Mol Cancer. 2021;20:100 pubmed publisher
Vaughan H, Zamboni C, Radant N, Bhardwaj P, Revai Lechtich E, Hassan L, et al. Poly(beta-amino ester) nanoparticles enable tumor-specific TRAIL secretion and a bystander effect to treat liver cancer. Mol Ther Oncolytics. 2021;21:377-388 pubmed publisher
Hao J, Ci X, Wang Y, Choi S, Sullivan S, Xue H, et al. GRB10 sustains AR activity by interacting with PP2A in prostate cancer cells. Int J Cancer. 2021;148:469-480 pubmed publisher
Tishchenko A, Azorín D, Vidal Brime L, Muñoz M, Arenas P, Pearce C, et al. Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells. Cancers (Basel). 2020;12: pubmed publisher
Sá Pessoa J, Przybyszewska K, Vasconcelos F, Dumigan A, Frank C, Hobley L, et al. Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses. MBio. 2020;11: pubmed publisher
Zecchin D, Moore C, Michailidis F, Horswell S, Rana S, Howell M, et al. Combined targeting of G protein-coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN-null triple negative breast cancer. EMBO Mol Med. 2020;12:e11987 pubmed publisher
Hoxha S, Shepard A, Troutman S, Diao H, Doherty J, Janiszewska M, et al. YAP-Mediated Recruitment of YY1 and EZH2 Represses Transcription of Key Cell-Cycle Regulators. Cancer Res. 2020;80:2512-2522 pubmed publisher
Morales Torres C, Wu M, Hobor S, Wainwright E, Martin M, Patel H, et al. Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis. Nat Commun. 2020;11:1792 pubmed publisher
Liu J, Chen H, Ma L, He Z, Wang D, Liu Y, et al. Light-induced control of protein destruction by opto-PROTAC. Sci Adv. 2020;6:eaay5154 pubmed publisher
Lei G, Zhang Y, Koppula P, Liu X, Zhang J, Lin S, et al. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Res. 2020;30:146-162 pubmed publisher
Liu G, Byrd A, Warner A, Pei F, Basha E, Buchanan A, et al. Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover. Mol Cell Biol. 2020;40: pubmed publisher
Herhaus L, Bhaskara R, Lystad A, Gestal Mato U, Covarrubias Pinto A, Bonn F, et al. TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease. EMBO Rep. 2020;21:e48317 pubmed publisher
Fehling S, Miller A, Garcia P, Vance R, Yoon K. The combination of BET and PARP inhibitors is synergistic in models of cholangiocarcinoma. Cancer Lett. 2020;468:48-58 pubmed publisher
Liu J, Yao Q, Xiao L, Ma W, Li F, Lai B, et al. PPARγ induces NEDD4 gene expression to promote autophagy and insulin action. FEBS J. 2020;287:529-545 pubmed publisher
Hart P, Kenny H, Grassl N, Watters K, Litchfield L, Coscia F, et al. Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk. Cell Rep. 2019;29:4086-4098.e6 pubmed publisher
Farrar C, Rouin G, Miller B, Raeman C, Mooney N, Hocking D. A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived Growth Factor-Induced Intracellular Calcium Release. Cells. 2019;8: pubmed publisher
Matre P, Mu X, Wu J, Danila D, Hall M, Kolonin M, et al. CRISPR/Cas9-Based Dystrophin Restoration Reveals a Novel Role for Dystrophin in Bioenergetics and Stress Resistance of Muscle Progenitors. Stem Cells. 2019;37:1615-1628 pubmed publisher
Holdgaard S, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen J, et al. Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nat Commun. 2019;10:4176 pubmed publisher
Gurrapu S, Franzolin G, Fard D, Accardo M, Medico E, Sarotto I, et al. Reverse signaling by semaphorin 4C elicits SMAD1/5- and ID1/3-dependent invasive reprogramming in cancer cells. Sci Signal. 2019;12: pubmed publisher
Martínez García D, Pérez Hernández M, Korrodi Gregório L, Quesada R, Ramos R, Baixeras N, et al. The Natural-Based Antitumor Compound T21 Decreases Survivin Levels through Potent STAT3 Inhibition in Lung Cancer Models. Biomolecules. 2019;9: pubmed publisher
Konishi S, Yano T, Tanaka H, Mizuno T, Kanoh H, Tsukita K, et al. Vinculin is critical for the robustness of the epithelial cell sheet paracellular barrier for ions. Life Sci Alliance. 2019;2: pubmed publisher
Thomas N, Choi H, Wei X, Wang L, Mishina Y, Guan J, et al. Autophagy Regulates Craniofacial Bone Acquisition. Calcif Tissue Int. 2019;: pubmed publisher
Kawakami Y, Hambright W, Takayama K, Mu X, Lu A, Cummins J, et al. Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice. Mol Ther Methods Clin Dev. 2019;14:64-76 pubmed publisher
Borghesan M, Fafián Labora J, Eleftheriadou O, Carpintero Fernández P, Pàez Ribes M, Vizcay Barrena G, et al. Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3. Cell Rep. 2019;27:3956-3971.e6 pubmed publisher
Wen T, Liu J, He X, Dong K, Hu G, Yu L, et al. Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation. Cell Death Differ. 2019;: pubmed publisher
Raven P, Lysakowski S, Tan Z, D Costa N, Moskalev I, Frees S, et al. Inhibition of GLI2 with antisense-oligonucleotides: A potential therapy for the treatment of bladder cancer. J Cell Physiol. 2019;234:20634-20647 pubmed publisher
Tomás Loba A, Manieri E, González Terán B, Mora A, Leiva Vega L, Santamans A, et al. p38γ is essential for cell cycle progression and liver tumorigenesis. Nature. 2019;568:557-560 pubmed publisher
Manieri E, Herrera Melle L, Mora A, Tomás Loba A, Leiva Vega L, Fernández D, et al. Adiponectin accounts for gender differences in hepatocellular carcinoma incidence. J Exp Med. 2019;216:1108-1119 pubmed publisher
Zhang Y, Koppula P, Gan B. Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1. Cell Cycle. 2019;18:773-783 pubmed publisher
Falero Perez J, Sorenson C, Sheibani N. Cyp1b1-deficient retinal astrocytes are more proliferative and migratory and are protected from oxidative stress and inflammation. Am J Physiol Cell Physiol. 2019;316:C767-C781 pubmed publisher
Lapointe F, Turcotte S, Veronneau S, Rola Pleszczynski M, Stankova J. Role of Protein Tyrosine Phosphatase Epsilon (PTPε) in Leukotriene D4-Induced CXCL8 Expression. J Pharmacol Exp Ther. 2019;369:270-281 pubmed publisher
Oury J, Liu Y, Topf A, Todorovic S, Hoedt E, Preethish Kumar V, et al. MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses. J Cell Biol. 2019;218:1686-1705 pubmed publisher
Liu Y, Fu Y, Wang Q, Li M, Zhou Z, Dabbagh D, et al. Proteomic profiling of HIV-1 infection of human CD4+ T cells identifies PSGL-1 as an HIV restriction factor. Nat Microbiol. 2019;4:813-825 pubmed publisher
Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, et al. SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Dev Cell. 2019;48:329-344.e5 pubmed publisher
Domke L, Franke W. The cell-cell junctions of mammalian testes: II. The lamellar smooth muscle monolayer cells of the peritubular wall are laterally connected by vertical adherens junctions-a novel architectonic cell-cell junction system. Cell Tissue Res. 2019;375:451-482 pubmed publisher
Fang F, VanCleave A, Helmuth R, Torres H, Rickel K, Wollenzien H, et al. Targeting the Wnt/β-catenin pathway in human osteosarcoma cells. Oncotarget. 2018;9:36780-36792 pubmed publisher
Lee C, Munuganti R, Peacock J, Dalal K, Jiao I, Shepherd A, et al. Targeting Semaphorin 3C in Prostate Cancer With Small Molecules. J Endocr Soc. 2018;2:1381-1394 pubmed publisher
Falero Perez J, Song Y, Zhao Y, Teixeira L, Sorenson C, Sheibani N. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. PLoS ONE. 2018;13:e0206756 pubmed publisher
Chauhan A, Liu X, Jing J, Lee H, Yadav R, Liu J, et al. STIM2 interacts with AMPK and regulates calcium-induced AMPK activation. FASEB J. 2018;:fj201801225R pubmed publisher
Farrar C, Hocking D. Assembly of fibronectin fibrils selectively attenuates platelet-derived growth factor-induced intracellular calcium release in fibroblasts. J Biol Chem. 2018;293:18655-18666 pubmed publisher
Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, et al. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018;20:1181-1192 pubmed publisher
de Jong S, Crequer A, Matos I, Hum D, Gunasekharan V, Lorenzo L, et al. The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses. J Exp Med. 2018;215:2289-2310 pubmed publisher
Robotti F, Bottan S, Fraschetti F, Mallone A, Pellegrini G, Lindenblatt N, et al. A micron-scale surface topography design reducing cell adhesion to implanted materials. Sci Rep. 2018;8:10887 pubmed publisher
Cappella M, Perfetti A, Cardinali B, Garcia Manteiga J, Carrara M, Provenzano C, et al. High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2. Cell Death Dis. 2018;9:729 pubmed publisher
Rizzolio S, Cagnoni G, Battistini C, Bonelli S, Isella C, Van Ginderachter J, et al. Neuropilin-1 upregulation elicits adaptive resistance to oncogene-targeted therapies. J Clin Invest. 2018;128:3976-3990 pubmed publisher
Yeo S, Paul R, Haas M, Wang C, Guan J. Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer. Autophagy. 2018;14:1214-1225 pubmed publisher
Choi H, Yuan H, Fang F, Wei X, Liu L, Li Q, et al. Tsc1 Regulates the Balance Between Osteoblast and Adipocyte Differentiation Through Autophagy/Notch1/β-Catenin Cascade. J Bone Miner Res. 2018;33:2021-2034 pubmed publisher
Perrotta C, Cervia D, Di Renzo I, Moscheni C, Bassi M, Campana L, et al. Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition. Front Immunol. 2018;9:1186 pubmed publisher
Hilfenhaus G, Nguyen D, Freshman J, Prajapati D, Ma F, Song D, et al. Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers. J Cell Biol. 2018;217:2813-2830 pubmed publisher
Kota S, Hou S, Guerrant W, Madoux F, Troutman S, Fernandez Vega V, et al. A novel three-dimensional high-throughput screening approach identifies inducers of a mutant KRAS selective lethal phenotype. Oncogene. 2018;37:4372-4384 pubmed publisher
Robichaux J, Elamin Y, Tan Z, Carter B, Zhang S, Liu S, et al. Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer. Nat Med. 2018;24:638-646 pubmed publisher
Janzen C, Lei M, Jeong I, Ganguly A, Sullivan P, Paharkova V, et al. Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction. PLoS ONE. 2018;13:e0193583 pubmed publisher
Gurrapu S, Pupo E, Franzolin G, Lanzetti L, Tamagnone L. Sema4C/PlexinB2 signaling controls breast cancer cell growth, hormonal dependence and tumorigenic potential. Cell Death Differ. 2018;25:1259-1275 pubmed publisher
Nguyen A, Nguyen T, Zhang J, Devireddy S, Zhou P, Karydas A, et al. Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proc Natl Acad Sci U S A. 2018;115:E2849-E2858 pubmed publisher
Ci Y, Li X, Chen M, Zhong J, North B, Inuzuka H, et al. SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation. Protein Cell. 2018;9:879-889 pubmed publisher
Liu X, Hayano S, Pan H, Inagaki M, Ninomiya Tsuji J, Sun H, et al. Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death. Genesis. 2018;56:e23093 pubmed publisher
Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, et al. Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Mol Cell. 2018;69:279-291.e5 pubmed publisher
Yan M, Qi H, Li J, Ye G, Shao Y, Li T, et al. Identification of SPOP related metabolic pathways in prostate cancer. Oncotarget. 2017;8:103032-103046 pubmed publisher
Ingallina E, Sorrentino G, Bertolio R, Lisek K, Zannini A, Azzolin L, et al. Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis. Nat Cell Biol. 2018;20:28-35 pubmed publisher
Kim J, Louhghalam A, Lee G, Schafer B, Wirtz D, Kim D. Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology. Nat Commun. 2017;8:2123 pubmed publisher
Rizzolio S, Battistini C, Cagnoni G, Apicella M, Vella V, Giordano S, et al. Downregulating Neuropilin-2 Triggers a Novel Mechanism Enabling EGFR-Dependent Resistance to Oncogene-Targeted Therapies. Cancer Res. 2018;78:1058-1068 pubmed publisher
Vassilev V, Platek A, Hiver S, Enomoto H, Takeichi M. Catenins Steer Cell Migration via Stabilization of Front-Rear Polarity. Dev Cell. 2017;43:463-479.e5 pubmed publisher
Mendoza P, SILVA P, Diaz J, Arriagada C, Canales J, Cerda O, et al. Calpain2 mediates Rab5-driven focal adhesion disassembly and cell migration. Cell Adh Migr. 2018;12:185-194 pubmed publisher
Dubois F, Alpha K, Turner C. Paxillin regulates cell polarization and anterograde vesicle trafficking during cell migration. Mol Biol Cell. 2017;28:3815-3831 pubmed publisher
Pera M, Larrea D, Guardia Laguarta C, Montesinos J, Velasco K, Agrawal R, et al. Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease. EMBO J. 2017;36:3356-3371 pubmed publisher
Wei H, Cui R, Bahr J, Zanesi N, Luo Z, Meng W, et al. miR-130a Deregulates PTEN and Stimulates Tumor Growth. Cancer Res. 2017;77:6168-6178 pubmed publisher
Liao Z, Kasirer Friede A, Shattil S. Optogenetic interrogation of integrin αVβ3 function in endothelial cells. J Cell Sci. 2017;130:3532-3541 pubmed publisher
Falero Perez J, Park S, Sorenson C, Sheibani N. PEDF expression affects retinal endothelial cell proangiogenic properties through alterations in cell adhesive mechanisms. Am J Physiol Cell Physiol. 2017;313:C405-C420 pubmed publisher
Korpal M, Puyang X, Jeremy Wu Z, Seiler R, Furman C, Oo H, et al. Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer. Nat Commun. 2017;8:103 pubmed publisher
Piotrowska I, Isalan M, Mielcarek M. Early transcriptional alteration of histone deacetylases in a murine model of doxorubicin-induced cardiomyopathy. PLoS ONE. 2017;12:e0180571 pubmed publisher
Pan H, Zhang H, Abraham P, Komatsu Y, Lyons K, Kaartinen V, et al. BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development. Dev Biol. 2017;429:260-270 pubmed publisher
Koppula P, Zhang Y, Shi J, Li W, Gan B. The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate. J Biol Chem. 2017;292:14240-14249 pubmed publisher
Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed publisher
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product information
Product No. :
V4505
Product Name :
Monoclonal Anti-Vinculin antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
VIN-11-5
Applications/Description :
Suitable for indirect immunofluorescence: 1:50 using cultured chicken fibroblasts; western blot; microarray
Species Reactivity :
mouse, bovine, chicken, human
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA