This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Vinblastine sulfate salt
catalog :
V1377
citations: 53
Reference
Park S, Zuber C, Roth J. Selective autophagy of cytosolic protein aggregates involves ribosome-free rough endoplasmic reticulum. Histochem Cell Biol. 2020;153:89-99 pubmed publisher
Molnár M, Lázár B, Sztán N, Végi B, Drobnyák Á, Tóth R, et al. Investigation of the Guinea fowl and domestic fowl hybrids as potential surrogate hosts for avian cryopreservation programmes. Sci Rep. 2019;9:14284 pubmed publisher
Arrázola M, Saquel C, Catalán R, Barrientos S, Hernandez D, Martinez N, et al. Axonal Degeneration Is Mediated by Necroptosis Activation. J Neurosci. 2019;39:3832-3844 pubmed publisher
Magtanong L, Ko P, To M, Cao J, Forcina G, Tarangelo A, et al. Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State. Cell Chem Biol. 2019;26:420-432.e9 pubmed publisher
Ramos S, Hughes M, Perry C. Altered skeletal muscle microtubule-mitochondrial VDAC2 binding is related to bioenergetic impairments after paclitaxel but not vinblastine chemotherapies. Am J Physiol Cell Physiol. 2019;316:C449-C455 pubmed publisher
Kochan Jamrozy K, Króliczewski J, Moszyńska A, Collawn J, Bartoszewski R. miRNA networks modulate human endothelial cell adaptation to cyclic hypoxia. Cell Signal. 2019;54:150-160 pubmed publisher
Thomas H, Zhang Y, Stefely J, Veiga S, Thomas G, Kozma S, et al. Mitochondrial Complex I Activity Is Required for Maximal Autophagy. Cell Rep. 2018;24:2404-2417.e8 pubmed publisher
Li L, Zviti R, Ha C, Wang Z, Hill J, Lin F. Forkhead box O3 (FoxO3) regulates kidney tubular autophagy following urinary tract obstruction. J Biol Chem. 2017;292:13774-13783 pubmed publisher
Gonzalez M, Vera D, Laiolo J, Joray M, Maccioni M, Palacios S, et al. Mechanism Underlying the Reversal of Drug Resistance in P-Glycoprotein-Expressing Leukemia Cells by Pinoresinol and the Study of a Derivative. Front Pharmacol. 2017;8:205 pubmed publisher
Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed publisher
Cisneros E, Roza C, Jackson N, López García J. A New Regulatory Mechanism for Kv7.2 Protein During Neuropathy: Enhanced Transport from the Soma to Axonal Terminals of Injured Sensory Neurons. Front Cell Neurosci. 2015;9:470 pubmed publisher
Fares M, Abedi Valugerdi M, Hassan M, Potácová Z. DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line. Biochem Biophys Res Commun. 2015;463:268-74 pubmed publisher
Maki T, Grimaldi A, Fuchigami S, Kaverina I, Hayashi I. CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics. J Mol Biol. 2015;427:2379-95 pubmed publisher
Newman Smith E, Kourakis M, Reeves W, Veeman M, Smith W. Reciprocal and dynamic polarization of planar cell polarity core components and myosin. elife. 2015;4:e05361 pubmed publisher
Gorbunov N, McDaniel D, Zhai M, Liao P, Garrison B, Kiang J. Autophagy and mitochondrial remodelling in mouse mesenchymal stromal cells challenged with Staphylococcus epidermidis. J Cell Mol Med. 2015;19:1133-50 pubmed publisher
Asada H, Tomiyasu H, Goto Koshino Y, Fujino Y, Ohno K, Tsujimoto H. Evaluation of the drug sensitivity and expression of 16 drug resistance-related genes in canine histiocytic sarcoma cell lines. J Vet Med Sci. 2015;77:677-84 pubmed publisher
Goldmacher V, Audette C, Guan Y, Sidhom E, Shah J, Whiteman K, et al. High-affinity accumulation of a maytansinoid in cells via weak tubulin interaction. PLoS ONE. 2015;10:e0117523 pubmed publisher
Chi S, Xie W, Zhang J, Xu S. Theoretical insight into the structural mechanism for the binding of vinblastine with tubulin. J Biomol Struct Dyn. 2015;33:2234-54 pubmed publisher
Yano K, Mita S, Morimoto K, Haraguchi T, Arakawa H, Yoshida M, et al. Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity, Measured with a Sensor. J Pharm Sci. 2015;104:2789-94 pubmed publisher
Chen Y, Chen J, Lin Y, Kitikiew S, Li H, Bai J, et al. Endogenous molecules induced by a pathogen-associated molecular pattern (PAMP) elicit innate immunity in shrimp. PLoS ONE. 2014;9:e115232 pubmed publisher
Kuboki M, Ito A, Simizu S, Umezawa K. Activation of apoptosis by caspase-3-dependent specific RelB cleavage in anticancer agent-treated cancer cells: involvement of positive feedback mechanism. Biochem Biophys Res Commun. 2015;456:810-4 pubmed publisher
Kasap C, Elemento O, Kapoor T. DrugTargetSeqR: a genomics- and CRISPR-Cas9-based method to analyze drug targets. Nat Chem Biol. 2014;10:626-8 pubmed publisher
Lin Y, Chen J, Morni W, Putra D, Huang C, Li C, et al. Vaccination enhances early immune responses in white shrimp Litopenaeus vannamei after secondary exposure to Vibrio alginolyticus. PLoS ONE. 2013;8:e69722 pubmed publisher
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W. Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 2011;7:e1002310 pubmed publisher
Krishnegowda G, Prakasha Gowda A, Tagaram H, Carroll K, Irby R, Sharma A, et al. Synthesis and biological evaluation of a novel class of isatin analogs as dual inhibitors of tubulin polymerization and Akt pathway. Bioorg Med Chem. 2011;19:6006-14 pubmed publisher
Friedrich V, Flores R, Muller A, Bi W, Peerschke E, Sehba F. Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage. J Neuroinflammation. 2011;8:103 pubmed publisher
Prinz H, Schmidt P, Böhm K, Baasner S, Muller K, Gerlach M, et al. Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization. Bioorg Med Chem. 2011;19:4183-91 pubmed publisher
Prinz H, Chamasmani B, Vogel K, Böhm K, Aicher B, Gerlach M, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011;54:4247-63 pubmed publisher
Ekins S, Williams A, Xu J. A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug Metab Dispos. 2010;38:2302-8 pubmed publisher
Greene N, Fisk L, Naven R, Note R, Patel M, Pelletier D. Developing structure-activity relationships for the prediction of hepatotoxicity. Chem Res Toxicol. 2010;23:1215-22 pubmed publisher
Surkau G, Böhm K, Muller K, Prinz H. Synthesis, antiproliferative activity and inhibition of tubulin polymerization by anthracenone-based oxime derivatives. Eur J Med Chem. 2010;45:3354-64 pubmed publisher
Nickel H, Schmidt P, Böhm K, Baasner S, Muller K, Gerlach M, et al. Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety. Eur J Med Chem. 2010;45:3420-38 pubmed publisher
Liu J, Wang X, Cheng F, Liou Y, Deng L. Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry. J Biol Chem. 2010;285:20904-14 pubmed publisher
Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher
Tundis R, Bonesi M, Deguin B, Loizzo M, Menichini F, Conforti F, et al. Cytotoxic activity and inhibitory effect on nitric oxide production of triterpene saponins from the roots of Physospermum verticillatum (Waldst & Kit) (Apiaceae). Bioorg Med Chem. 2009;17:4542-7 pubmed publisher
Mayer F, Mayer N, Chinn L, Pinsonneault R, Kroetz D, Bainton R. Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. J Neurosci. 2009;29:3538-50 pubmed publisher
Prinz H, Schmidt P, Böhm K, Baasner S, Muller K, Unger E, et al. 10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2009;52:1284-94 pubmed publisher
Fortin J, Côté M, Lacroix J, Desjardins M, Petitclerc E, C Gaudreault R. Selective alkylation of beta(II)-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents. Bioorg Med Chem. 2008;16:7277-90 pubmed publisher
Zuse A, Schmidt P, Baasner S, Böhm K, Muller K, Gerlach M, et al. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2007;50:6059-66 pubmed
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Williams N, Burgett A, Atkins A, Wang X, Harran P, McKnight S. Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity. Proc Natl Acad Sci U S A. 2007;104:2074-9 pubmed
Zuse A, Schmidt P, Baasner S, Böhm K, Muller K, Gerlach M, et al. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2006;49:7816-25 pubmed
Morrell A, Jayaraman M, Nagarajan M, Fox B, Meckley M, Ioanoviciu A, et al. Evaluation of indenoisoquinoline topoisomerase I inhibitors using a hollow fiber assay. Bioorg Med Chem Lett. 2006;16:4395-9 pubmed
Chen G, Duran G, Mangili A, Beketic Oreskovic L, Sikic B. MDR 1 activation is the predominant resistance mechanism selected by vinblastine in MES-SA cells. Br J Cancer. 2000;83:892-8 pubmed
Tashiro E, Simizu S, Takada M, Umezawa K, Imoto M. Caspase-3 activation is not responsible for vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in human small cell lung carcinoma Ms-1 cells. Jpn J Cancer Res. 1998;89:940-6 pubmed
Jordan M, Wilson L. Use of drugs to study role of microtubule assembly dynamics in living cells. Methods Enzymol. 1998;298:252-76 pubmed
Jordan A, Hadfield J, Lawrence N, McGown A. Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle. Med Res Rev. 1998;18:259-96 pubmed
Rai S, Wolff J. The C terminus of beta-tubulin regulates vinblastine-induced tubulin polymerization. Proc Natl Acad Sci U S A. 1998;95:4253-7 pubmed
Blagosklonny M, Giannakakou P, El Deiry W, Kingston D, Higgs P, Neckers L, et al. Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death. Cancer Res. 1997;57:130-5 pubmed
Panda D, Jordan M, Chu K, Wilson L. Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends. J Biol Chem. 1996;271:29807-12 pubmed
Tishler R, Lamppu D. The interaction of taxol and vinblastine with radiation induction of p53 and p21 WAF1/CIP1. Br J Cancer Suppl. 1996;27:S82-5 pubmed
Lobert S, Vulevic B, Correia J. Interaction of vinca alkaloids with tubulin: a comparison of vinblastine, vincristine, and vinorelbine. Biochemistry. 1996;35:6806-14 pubmed
Zhou Pan X, Seree E, Zhou X, Placidi M, Maurel P, Barra Y, et al. Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions. Cancer Res. 1993;53:5121-6 pubmed
product information
Catalog Number :
V1377
Product Name :
Vinblastine sulfate salt
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥97% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA