Reference |
---|
Zurlo G, Liu X, Takada M, Fan C, Simon J, Ptacek T, et al. Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer. Nat Commun. 2019;10:5177 pubmed publisher
|
Audano M, Pedretti S, Crestani M, Caruso D, De Fabiani E, Mitro N. Mitochondrial dysfunction increases fatty acid β-oxidation and translates into impaired neuroblast maturation. FEBS Lett. 2019;593:3173-3189 pubmed publisher
|
Rosina M, Langone F, Giuliani G, Cerquone Perpetuini A, Reggio A, Calderone A, et al. Osteogenic differentiation of skeletal muscle progenitor cells is activated by the DNA damage response. Sci Rep. 2019;9:5447 pubmed publisher
|
Vila O, Uzel S, Ma S, Williams D, Pak J, Kamm R, et al. Quantification of human neuromuscular function through optogenetics. Theranostics. 2019;9:1232-1246 pubmed publisher
|
Wegner M, Diehl V, Bittl V, de Bruyn R, Wiechmann S, Matthess Y, et al. Circular synthesized CRISPR/Cas gRNAs for functional interrogations in the coding and noncoding genome. elife. 2019;8: pubmed publisher
|
Hong H, Samborskyy M, Zhou Y, Leadlay P. C-Nucleoside Formation in the Biosynthesis of the Antifungal Malayamycin A. Cell Chem Biol. 2019;26:493-501.e5 pubmed publisher
|
Bajzikova M, Kovarova J, Coelho A, Boukalova S, Oh S, Rohlenova K, et al. Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. Cell Metab. 2019;29:399-416.e10 pubmed publisher
|
Wang X, Li Q, Liu C, Hall P, Jiang J, Katchis C, et al. Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration. Cell Rep. 2018;24:2540-2552.e6 pubmed publisher
|
Hitzel J, Lee E, Zhang Y, Bibli S, Li X, Zukunft S, et al. Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Nat Commun. 2018;9:2292 pubmed publisher
|
Kays J, Zhang Y, Khorodova A, Strichartz G, Nicol G. Peripheral Synthesis of an Atypical Protein Kinase C Mediates the Enhancement of Excitability and the Development of Mechanical Hyperalgesia Produced by Nerve Growth Factor. Neuroscience. 2018;371:420-432 pubmed publisher
|
Heffernan C, Jain M, Liu T, Kim H, Barretto K, Li H, et al. Nectin-like 4 Complexes with Choline Transporter-like Protein-1 and Regulates Schwann Cell Choline Homeostasis and Lipid Biogenesis in Vitro. J Biol Chem. 2017;292:4484-4498 pubmed publisher
|
Barrow J, Balsa E, Verdeguer F, Tavares C, Soustek M, Hollingsworth L, et al. Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations. Mol Cell. 2016;64:163-175 pubmed publisher
|
Passerini V, Ozeri Galai E, de Pagter M, Donnelly N, Schmalbrock S, Kloosterman W, et al. The presence of extra chromosomes leads to genomic instability. Nat Commun. 2016;7:10754 pubmed publisher
|
Zhang N, Liu Y, Jeong H. Drug-Drug Interaction Potentials of Tyrosine Kinase Inhibitors via Inhibition of UDP-Glucuronosyltransferases. Sci Rep. 2015;5:17778 pubmed publisher
|
Lee J, Ha S, Cho E, Choi I. Resveratrol as a Bioenhancer to Improve Anti-Inflammatory Activities of Apigenin. Nutrients. 2015;7:9650-61 pubmed publisher
|
Ma C, Hao Z, Huysmans G, Lesiuk A, Bullough P, Wang Y, et al. A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Transporters. PLoS ONE. 2015;10:e0143010 pubmed publisher
|
Holden M, Carter M, Wu C, Wolfer J, Codner E, Sussman M, et al. Photolithographic Synthesis of High-Density DNA and RNA Arrays on Flexible, Transparent, and Easily Subdivided Plastic Substrates. Anal Chem. 2015;87:11420-8 pubmed publisher
|
Li P, Tsai Y, Lee M, Chen C. Increased Histone Deacetylase Activity Involved in the Suppressed Invasion of Cancer Cells Survived from ALA-Mediated Photodynamic Treatment. Int J Mol Sci. 2015;16:23994-4010 pubmed publisher
|
Suddala K, Wang J, Hou Q, Walter N. Mg(2+) shifts ligand-mediated folding of a riboswitch from induced-fit to conformational selection. J Am Chem Soc. 2015;137:14075-83 pubmed publisher
|
Wang Q, Yang X, Yang X, Wang K, Zhang H, Liu P. An enzyme-free colorimetric assay using hybridization chain reaction amplification and split aptamers. Analyst. 2015;140:7657-62 pubmed publisher
|
Liu S, Xu H, Yu J, Li D, Li M, Qiao X, et al. Novel imidazolium-embedded N,N-dimethylaminopropyl-functionalized silica-based stationary phase for hydrophilic interaction/reversed-phase mixed-mode chromatography. Anal Bioanal Chem. 2015;407:8989-97 pubmed publisher
|
Probert F, Ruiz Rodado V, Zhang X, te Vruchte D, Claridge T, Edgar M, et al. Urinary excretion and metabolism of miglustat and valproate in patients with Niemann-Pick type C1 disease: One- and two-dimensional solution-state (1)H NMR studies. J Pharm Biomed Anal. 2016;117:276-88 pubmed publisher
|
Allen S, Duffy L, Shaw P, Grierson A. Altered age-related changes in bioenergetic properties and mitochondrial morphology in fibroblasts from sporadic amyotrophic lateral sclerosis patients. Neurobiol Aging. 2015;36:2893-903 pubmed publisher
|
Liu Z, Zhang X, Wang W, Zhang J, Li Z, Gui J. Molecular characterization and expression of an oocyte-specific histone stem-loop binding protein in Carassius gibelio. Comp Biochem Physiol B Biochem Mol Biol. 2015;190:46-53 pubmed publisher
|
Yang X, Chen J, Liu C, Peng J, Wee Y, Han X, et al. Selectively Constrained RNA Editing Regulation Crosstalks with piRNA Biogenesis in Primates. Mol Biol Evol. 2015;32:3143-57 pubmed publisher
|
Wang Q, Ye M, Xu L, Shi Z. A reversed-phase/hydrophilic interaction mixed-mode C18-Diol stationary phase for multiple applications. Anal Chim Acta. 2015;888:182-90 pubmed publisher
|
Willmann L, Erbes T, Halbach S, Brummer T, Jager M, Hirschfeld M, et al. Exometabolom analysis of breast cancer cell lines: Metabolic signature. Sci Rep. 2015;5:13374 pubmed publisher
|
KamÄeva T, BjÃ¥nes T, Svardal A, Riedel B, Schjøtt J, Eide T. Liquid chromatography/tandem mass spectrometry method for simultaneous quantification of eight endogenous nucleotides and the intracellular gemcitabine metabolite dFdCTP in human peripheral blood mononuclear cells. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;1001:212-20 pubmed publisher
|
Kim S, Lee H, Kim K, Kim H, Moon A. Noninvasive Biomarker Candidates for Cadmium-Induced Nephrotoxicity by 2DE/MALDI-TOF-MS and SILAC/LC-MS Proteomic Analyses. Toxicol Sci. 2015;148:167-82 pubmed publisher
|
Abd Elsayed A, Ikeda R, Jia Z, Ling J, Zuo X, Li M, et al. KCNQ channels in nociceptive cold-sensing trigeminal ganglion neurons as therapeutic targets for treating orofacial cold hyperalgesia. Mol Pain. 2015;11:45 pubmed publisher
|
Ene I, Walker L, Schiavone M, Lee K, Martin Yken H, Dague E, et al. Cell Wall Remodeling Enzymes Modulate Fungal Cell Wall Elasticity and Osmotic Stress Resistance. MBio. 2015;6:e00986 pubmed publisher
|
Zenger K, Agnolet S, Schneider B, Kraus B. Biotransformation of Flavokawains A, B, and C, Chalcones from Kava (Piper methysticum), by Human Liver Microsomes. J Agric Food Chem. 2015;63:6376-85 pubmed publisher
|
Pawluczyk I, Najafabadi M, Brown J, Bevington A, Topham P. Sialic acid supplementation ameliorates puromycin aminonucleoside nephrosis in rats. Lab Invest. 2015;95:1019-28 pubmed publisher
|
Franke L, ÄŒožÃková D, Smirnou D, Hermannová M, Hanová T, RůžiÄková A, et al. Simultaneous determination of intracellular UDP-sugars in hyaluronic acid-producing Streptococcus zooepidemicus. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;997:194-9 pubmed publisher
|
Wang T, Chen Y, Ma J, Zhang X, Zhang L, Zhang Y. Ionic liquid-based zwitterionic organic polymer monolithic column for capillary hydrophilic interaction chromatography. Analyst. 2015;140:5585-92 pubmed publisher
|
Liang S, Ge G, Xia Y, Zhang J, Qi X, Tu C, et al. In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis. J Pharm Sci. 2015;104:3557-64 pubmed publisher
|
Essaid D, Chaminade P, Maillard P, Kasselouri A. Lipophilicity of porphyrins and their retention in IAM, C8-C18 and HILIC chromatographic systems. J Pharm Biomed Anal. 2015;114:227-40 pubmed publisher
|
Feng C, Zhu J, Sun J, Jiang W, Wang L. Hairpin assembly circuit-based fluorescence cooperative amplification strategy for enzyme-free and label-free detection of small molecule. Talanta. 2015;143:101-106 pubmed publisher
|
Lee E, Angka L, Rota S, Hanlon T, Mitchell A, Hurren R, et al. Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death. Cancer Res. 2015;75:2478-88 pubmed publisher
|
Hayashi C, Takibuchi G, Shimizu A, Mito T, Ishikawa K, Nakada K, et al. A somatic T15091C mutation in the Cytb gene of mouse mitochondrial DNA dominantly induces respiration defects. Biochem Biophys Res Commun. 2015;463:1021-7 pubmed publisher
|
Charif M, Titah S, Roubertie A, Desquiret Dumas V, Gueguen N, Meunier I, et al. Optic neuropathy, cardiomyopathy, cognitive disability in patients with a homozygous mutation in the nuclear MTO1 and a mitochondrial MT-TF variant. Am J Med Genet A. 2015;167A:2366-74 pubmed publisher
|
Villacrés C, Tayi V, Lattová E, Perreault H, Butler M. Low glucose depletes glycan precursors, reduces site occupancy and galactosylation of a monoclonal antibody in CHO cell culture. Biotechnol J. 2015;10:1051-66 pubmed publisher
|
Jain S, Stroopinsky D, Yin L, Rosenblatt J, Alam M, Bhargava P, et al. Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma. Blood. 2015;126:354-62 pubmed publisher
|
Xue Y, Shi W, Zhu B, Gu X, Wang Y, Yan C. Polyethyleneimine-grafted boronate affinity materials for selective enrichment of cis-diol-containing compounds. Talanta. 2015;140:1-9 pubmed publisher
|
Park J, Byun J, Shim W, Kim S, Kim M. High-sensitivity detection of ATP using a localized surface plasmon resonance (LSPR) sensor and split aptamers. Biosens Bioelectron. 2015;73:26-31 pubmed publisher
|
Peng M, Ostrovsky J, Kwon Y, Polyak E, Licata J, Tsukikawa M, et al. Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease. Hum Mol Genet. 2015;24:4829-47 pubmed publisher
|
Daghir Wojtkowiak E, Wiczling P, Bocian S, Kubik Å, KoÅ›liÅ„ski P, Buszewski B, et al. Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography. J Chromatogr A. 2015;1403:54-62 pubmed publisher
|
Lekatz L, Swanson T, Camacho L, Van Emon M, Schauer C, Maddock Carlin K, et al. Maternal metabolizable protein restriction during late gestation on uterine and umbilical blood flows and maternal and fetal amino acid concentrations near term in sheep. Anim Reprod Sci. 2015;158:115-25 pubmed publisher
|
Sasaki Y, Margolin Z, Borgo B, Havranek J, Milbrandt J. Characterization of Leber Congenital Amaurosis-associated NMNAT1 Mutants. J Biol Chem. 2015;290:17228-38 pubmed publisher
|
Wen Y, Zhan Y, Liu H, Zhao T, Yang L, Zhang H, et al. Yi Qi Qing Re Gao formula ameliorates puromycin aminonucleoside-induced nephrosis by suppressing inflammation and apoptosis. BMC Complement Altern Med. 2015;15:155 pubmed publisher
|
Gaffney P, Kim J, Valtcheva I, Williams G, Anson M, Buswell A, et al. Liquid-Phase Synthesis of 2'-Methyl-RNA on a Homostar Support through Organic-Solvent Nanofiltration. Chemistry. 2015;21:9535-43 pubmed publisher
|
Lušin T, Mrhar A, Trontelj J. UGT1A1*28 polymorphism influences glucuronidation of bazedoxifene. Pharmazie. 2015;70:94-6 pubmed
|
Wang Z, Zheng Y, Zhao B, Zhang Y, Liu Z, Xu J, et al. Human metabolic responses to chronic environmental polycyclic aromatic hydrocarbon exposure by a metabolomic approach. J Proteome Res. 2015;14:2583-93 pubmed publisher
|
Basak S, Desai D, Rho E, Ramos R, Maurel P, Kim H. E-cadherin enhances neuregulin signaling and promotes Schwann cell myelination. Glia. 2015;63:1522-36 pubmed publisher
|
Lassoued I, Mora L, Nasri R, Aydi M, Toldrá F, Aristoy M, et al. Characterization, antioxidative and ACE inhibitory properties of hydrolysates obtained from thornback ray (Raja clavata) muscle. J Proteomics. 2015;128:458-68 pubmed publisher
|
Haraguchi A, Kinoshita K, Fukai M, Koyama K. A novel nucleoside from the edible mushroom, Tricholoma japonicum. J Nat Med. 2015;69:584-8 pubmed publisher
|
He Y, Cui J, He T, Bi Y. 5-azacytidine promotes terminal differentiation of hepatic progenitor cells. Mol Med Rep. 2015;12:2872-8 pubmed publisher
|
Ogbodu R, Amuhaya E, Mashazi P, Nyokong T. Photophysical properties of zinc phthalocyanine-uridine single walled carbon nanotube--conjugates. Spectrochim Acta A Mol Biomol Spectrosc. 2015;149:231-9 pubmed publisher
|
Gao S, Yu Y, Ma Z, Sun H, Zhang Y, Wang X, et al. NMDAR-Mediated Hippocampal Neuronal Death is Exacerbated by Activities of ASIC1a. Neurotox Res. 2015;28:122-37 pubmed publisher
|
Fischer E, Almási A, Bojcsev S, Fischer T, Kovács N, Perjesi P. Effect of experimental diabetes and insulin replacement on intestinal metabolism and excretion of 4-nitrophenol in rats. Can J Physiol Pharmacol. 2015;93:459-64 pubmed publisher
|
Varea O, Martín de Saavedra M, Kopeikina K, Schürmann B, Fleming H, Fawcett Patel J, et al. Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons. Proc Natl Acad Sci U S A. 2015;112:6176-81 pubmed publisher
|
Bocian S, Buszewski B. Comparison of retention properties of stationary phases imitated cell membrane in RP HPLC. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;990:198-202 pubmed publisher
|
Zhu X, He X, Wang W, Zhou Q, Yu Z, Dai Y, et al. MTO1 worked as a modifier in the aminoglycosides sensitivity of yeast carrying a mitochondrial 15S rRNA C1477G mutation. PLoS ONE. 2015;10:e0124200 pubmed publisher
|
Ortiz D, Guiguemde W, Johnson A, Elya C, Anderson J, Clark J, et al. Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds. PLoS ONE. 2015;10:e0123598 pubmed publisher
|
Li C, Li J, Kays J, Guerrero M, Nicol G. Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3. J Neuroinflammation. 2015;12:70 pubmed publisher
|
Sugiura H, Yasuda S, Katsurabayashi S, Kawano H, Endo K, Takasaki K, et al. Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex. Nat Commun. 2015;6:6842 pubmed publisher
|
Wojewoda M, Walczak J, Duszyński J, Szczepanowska J. Selenite activates the ATM kinase-dependent DNA repair pathway in human osteosarcoma cells with mitochondrial dysfunction. Biochem Pharmacol. 2015;95:170-6 pubmed publisher
|
Lee S, Heo H, Jeong S, Kim H, Song I, Ko K, et al. Low abundance of mitochondrial DNA changes mitochondrial status and renders cells resistant to serum starvation and sodium nitroprusside insult. Cell Biol Int. 2015;39:865-72 pubmed publisher
|
Chen J, Shi Q, Wang Y, Li Z, Wang S. Dereplication of known nucleobase and nucleoside compounds in natural product extracts by capillary electrophoresis-high resolution mass spectrometry. Molecules. 2015;20:5423-37 pubmed publisher
|
Fayzulin R, Perez M, Kozhukhar N, Spadafora D, Wilson G, Alexeyev M. A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions. Nucleic Acids Res. 2015;43:e62 pubmed publisher
|
Chu X, Shih S, Shaw R, Hentze H, Chan G, Owens K, et al. Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans. Drug Metab Dispos. 2015;43:851-63 pubmed publisher
|
Derissen E, Hillebrand M, Rosing H, Schellens J, Beijnen J. Development of an LC-MS/MS assay for the quantitative determination of the intracellular 5-fluorouracil nucleotides responsible for the anticancer effect of 5-fluorouracil. J Pharm Biomed Anal. 2015;110:58-66 pubmed publisher
|
François Moutal L, Wang Y, Moutal A, Cottier K, Melemedjian O, Yang X, et al. A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Pain. 2015;156:1247-64 pubmed publisher
|
Miyagawa Y, Marino P, Verlengia G, Uchida H, Goins W, Yokota S, et al. Herpes simplex viral-vector design for efficient transduction of nonneuronal cells without cytotoxicity. Proc Natl Acad Sci U S A. 2015;112:E1632-41 pubmed publisher
|
Yuan L, Qian S, Xiao Y, Sun H, Zeng S. Homo- and hetero-dimerization of human UDP-glucuronosyltransferase 2B7 (UGT2B7) wild type and its allelic variants affect zidovudine glucuronidation activity. Biochem Pharmacol. 2015;95:58-70 pubmed publisher
|
Schüll S, Günther S, Brodesser S, Seeger J, Tosetti B, Wiegmann K, et al. Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6. Cell Death Dis. 2015;6:e1691 pubmed publisher
|
Hartinger J, Veselý P, NetÃková I, MatouÅ¡ková E, Petruželka L. The protective effect of pyrimidine nucleosides on human HaCaT keratinocytes treated with 5-FU. Anticancer Res. 2015;35:1303-10 pubmed
|
Ibares FrÃas L, Gallego P, Cantalapiedra RodrÃguez R, Valsero M, Mar S, Merayo Lloves J, et al. Tissue reaction after intrastromal corneal ring implantation in an experimental animal model. Graefes Arch Clin Exp Ophthalmol. 2015;253:1071-83 pubmed publisher
|
Zhang X, Dong D, Wang H, Ma Z, Wang Y, Wu B. Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay. Mol Pharm. 2015;12:1268-78 pubmed publisher
|
Valakh V, Frey E, Babetto E, Walker L, DiAntonio A. Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury. Neurobiol Dis. 2015;77:13-25 pubmed publisher
|
Liang T, Fu Q, Shen A, Wang H, Jin Y, Xin H, et al. Preparation and chromatographic evaluation of a newly designed steviol glycoside modified-silica stationary phase in hydrophilic interaction liquid chromatography and reversed phase liquid chromatography. J Chromatogr A. 2015;1388:110-8 pubmed publisher
|
Jaramillo M, Briehl M, Batinic Haberle I, Tome M. Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells. Free Radic Biol Med. 2015;83:89-100 pubmed publisher
|
Zhou J, Zhou M, Yang F, Liu C, Pan R, Chang Q, et al. Involvement of the inhibition of intestinal glucuronidation in enhancing the oral bioavailability of resveratrol by labrasol containing nanoemulsions. Mol Pharm. 2015;12:1084-95 pubmed publisher
|
Egashira Y, Takase M, Takamori S. Monitoring of vacuolar-type H+ ATPase-mediated proton influx into synaptic vesicles. J Neurosci. 2015;35:3701-10 pubmed publisher
|
Lim T, Shi X, Johnson J, Rone M, Antel J, David S, et al. Peripheral nerve injury induces persistent vascular dysfunction and endoneurial hypoxia, contributing to the genesis of neuropathic pain. J Neurosci. 2015;35:3346-59 pubmed publisher
|
Gascard P, Bilenky M, Sigaroudinia M, Zhao J, Li L, Carles A, et al. Epigenetic and transcriptional determinants of the human breast. Nat Commun. 2015;6:6351 pubmed publisher
|
Gradinaru J, Romand S, Geiser L, Carrupt P, Spaggiari D, Rudaz S. Inhibition screening method of microsomal UGTs using the cocktail approach. Eur J Pharm Sci. 2015;71:35-45 pubmed publisher
|
Sun J, Liu Q, Ahluwalia D, Li W, Meng F, Wang Y, et al. Efficacy and safety of the hypoxia-activated prodrug TH-302 in combination with gemcitabine and nab-paclitaxel in human tumor xenograft models of pancreatic cancer. Cancer Biol Ther. 2015;16:438-49 pubmed publisher
|
Blount J, Redan B, Ferruzzi M, Reuhs B, Cooper B, Harwood J, et al. Synthesis and quantitative analysis of plasma-targeted metabolites of catechin and epicatechin. J Agric Food Chem. 2015;63:2233-40 pubmed publisher
|
Li M, Wang F, Huang Y, Du F, Zhong C, Olaleye O, et al. Systemic exposure to and disposition of catechols derived from Salvia miltiorrhiza roots (Danshen) after intravenous dosing DanHong injection in human subjects, rats, and dogs. Drug Metab Dispos. 2015;43:679-90 pubmed publisher
|
Lee J, Noh C, Yim C, Jeong Y, Ahn S, Lee W, et al. Kinetics of the Absorption, Distribution, Metabolism, and Excretion of Lobeglitazone, a Novel Activator of Peroxisome Proliferator-Activated Receptor Gamma in Rats. J Pharm Sci. 2015;104:3049-59 pubmed publisher
|
Xia Y, Ge G, Wang P, Liang S, He Y, Ning J, et al. Structural modifications at the C-4 position strongly affect the glucuronidation of 6,7-dihydroxycoumarins. Drug Metab Dispos. 2015;43:553-60 pubmed publisher
|
Hung S, Marrache S, Cummins S, Bhutia Y, Mody H, Hooks S, et al. Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: overcoming transport defects using a nanoparticle approach. Cancer Lett. 2015;359:233-40 pubmed publisher
|
Quan E, Wang H, Dong D, Zhang X, Wu B. Characterization of chrysin glucuronidation in UGT1A1-overexpressing HeLa cells: elucidating the transporters responsible for efflux of glucuronide. Drug Metab Dispos. 2015;43:433-43 pubmed publisher
|
Wang X, Gerdes H. Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells. Cell Death Differ. 2015;22:1181-91 pubmed publisher
|
Freeman S, Desmazières A, Simonnet J, Gatta M, Pfeiffer F, Aigrot M, et al. Acceleration of conduction velocity linked to clustering of nodal components precedes myelination. Proc Natl Acad Sci U S A. 2015;112:E321-8 pubmed publisher
|
Al Subeihi A, Alhusainy W, Kiwamoto R, Spenkelink B, van Bladeren P, Rietjens I, et al. Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations. Toxicol Appl Pharmacol. 2015;283:117-26 pubmed publisher
|
Wilkins H, Carl S, Weber S, Ramanujan S, Festoff B, Linseman D, et al. Mitochondrial lysates induce inflammation and Alzheimer's disease-relevant changes in microglial and neuronal cells. J Alzheimers Dis. 2015;45:305-18 pubmed publisher
|
Gault W, Enyedi B, Niethammer P. Osmotic surveillance mediates rapid wound closure through nucleotide release. J Cell Biol. 2014;207:767-82 pubmed publisher
|
Jeon J, Oh S, Lee J, Ryu C, Kim Y, Lee B, et al. Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice. Food Chem Toxicol. 2015;76:94-102 pubmed publisher
|
Gallagher W, Deshpande P, Li J, Katipally K, Sausker J. A Claisen approach to 4'-Ed4T. Org Lett. 2015;17:14-7 pubmed publisher
|
Damaraju V, Kuzma M, Mowles D, Cass C, Sawyer M. Interactions of multitargeted kinase inhibitors and nucleoside drugs: Achilles heel of combination therapy?. Mol Cancer Ther. 2015;14:236-45 pubmed publisher
|
Nassar K, Tura A, Lüke J, Lüke M, Grisanti S, Grisanti S. A p38 MAPK inhibitor improves outcome after glaucoma filtration surgery. J Glaucoma. 2015;24:165-78 pubmed publisher
|
AydoÄŸan C. Open-tubular CEC with a new triethanolamine bonded stationary phase for biomolecule separation. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;976-977:27-32 pubmed publisher
|
Kok M, Somsen G, de Jong G. Comparison of capillary electrophoresis-mass spectrometry and hydrophilic interaction chromatography-mass spectrometry for anionic metabolic profiling of urine. Talanta. 2015;132:1-7 pubmed publisher
|
Molgaard S, Ulrichsen M, Boggild S, Holm M, Vaegter C, Nyengaard J, et al. Immunohistochemical visualization of mouse interneuron subtypes. F1000Res. 2014;3:242 pubmed publisher
|
Borkar R, Bhandi M, Dubey A, Nandekar P, Sangamwar A, Banerjee S, et al. Plasma protein binding, pharmacokinetics, tissue distribution and CYP450 biotransformation studies of fidarestat by ultra high performance liquid chromatography-high resolution mass spectrometry. J Pharm Biomed Anal. 2015;102:386-99 pubmed publisher
|
Wang W, Yoshikawa M, Han B, Izumi N, Tomari Y, Weng Z, et al. The initial uridine of primary piRNAs does not create the tenth adenine that Is the hallmark of secondary piRNAs. Mol Cell. 2014;56:708-16 pubmed publisher
|
Lee S, Fiene A, Li W, Hanck T, Brylev K, Fedorov V, et al. Polyoxometalates--potent and selective ecto-nucleotidase inhibitors. Biochem Pharmacol. 2015;93:171-81 pubmed publisher
|
Lee S, Park J, Kim D, Bae S, Chin Y, Oh E, et al. In vitro selective inhibition of human UDP-glucuronosyltransferase (UGT) 1A4 by finasteride, and prediction of in vivo drug-drug interactions. Toxicol Lett. 2015;232:458-65 pubmed publisher
|
Tyteca E, Guillarme D, Desmet G. Use of individual retention modeling for gradient optimization in hydrophilic interaction chromatography: separation of nucleobases and nucleosides. J Chromatogr A. 2014;1368:125-31 pubmed publisher
|
Grill A, Koniar B, Panyam J. Co-delivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin. Drug Deliv Transl Res. 2014;4:344-52 pubmed publisher
|
Polo M, Alegre F, Funes H, Blas Garcia A, Victor V, Esplugues J, et al. Mitochondrial (dys)function - a factor underlying the variability of efavirenz-induced hepatotoxicity?. Br J Pharmacol. 2015;172:1713-27 pubmed publisher
|
Sun H, Zhang T, Wu Z, Wu B. Warfarin is an effective modifier of multiple UDP-glucuronosyltransferase enzymes: evaluation of its potential to alter the pharmacokinetics of zidovudine. J Pharm Sci. 2015;104:244-56 pubmed publisher
|
Rodrigues Ribeiro R, Alvarenga E, Calió M, Paredes Gamero E, Ferreira A. Dual role of P2 receptors during osteoblast differentiation. Cell Biochem Biophys. 2015;71:1225-33 pubmed publisher
|
Evstafieva A, Garaeva A, Khutornenko A, Klepikova A, Logacheva M, Penin A, et al. A sustained deficiency of mitochondrial respiratory complex III induces an apoptotic cell death through the p53-mediated inhibition of pro-survival activities of the activating transcription factor 4. Cell Death Dis. 2014;5:e1511 pubmed publisher
|
McCreedy D, Wilems T, Xu H, Butts J, Brown C, Smith A, et al. Survival, Differentiation, and Migration of High-Purity Mouse Embryonic Stem Cell-derived Progenitor Motor Neurons in Fibrin Scaffolds after Sub-Acute Spinal Cord Injury. Biomater Sci. 2014;2:1672-1682 pubmed
|
Lamas N, Johnson Kerner B, Roybon L, Kim Y, Garcia Diaz A, Wichterle H, et al. Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures. PLoS ONE. 2014;9:e110324 pubmed publisher
|
Shen F, Huang W, Huang J, Xiong J, Yang Y, Wu K, et al. Decreased N(6)-methyladenosine in peripheral blood RNA from diabetic patients is associated with FTO expression rather than ALKBH5. J Clin Endocrinol Metab. 2015;100:E148-54 pubmed publisher
|
Mickiewicz B, Heard B, Chau J, Chung M, Hart D, Shrive N, et al. Metabolic profiling of synovial fluid in a unilateral ovine model of anterior cruciate ligament reconstruction of the knee suggests biomarkers for early osteoarthritis. J Orthop Res. 2015;33:71-7 pubmed publisher
|
Liu X, Wang W, Samarsky D, Liu L, Xu Q, Zhang W, et al. Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA. Nucleic Acids Res. 2014;42:11805-17 pubmed publisher
|
Wen Y, Li J, Tan Y, Qin J, Xie X, Wang L, et al. Angelica Sinensis polysaccharides stimulated UDP-sugar synthase genes through promoting gene expression of IGF-1 and IGF1R in chondrocytes: promoting anti-osteoarthritic activity. PLoS ONE. 2014;9:e107024 pubmed publisher
|
Teh J, Zhu W, Ilkayeva O, Li Y, Gooding J, Casey P, et al. Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene. 2015;34:3296-304 pubmed publisher
|
Meseguer S, MartÃnez Zamora A, GarcÃa Arumà E, Andreu A, Armengod M. The ROS-sensitive microRNA-9/9* controls the expression of mitochondrial tRNA-modifying enzymes and is involved in the molecular mechanism of MELAS syndrome. Hum Mol Genet. 2015;24:167-84 pubmed publisher
|
Eckle V, Grasshoff C, Mirakaj V, O Neill P, Berry N, Leuwer M, et al. 4-bromopropofol decreases action potential generation in spinal neurons by inducing a glycine receptor-mediated tonic conductance. Br J Pharmacol. 2014;171:5790-801 pubmed publisher
|
Ishida K, Kuboshima M, Morita H, Maeda H, Okamoto A, Takeuchi M, et al. Diversity in mRNA expression of the serine-type carboxypeptidase ocpG in Aspergillus oryzae through intron retention. Biosci Biotechnol Biochem. 2014;78:1328-36 pubmed publisher
|
Qiao L, Wang S, Li H, Shan Y, Dou A, Shi X, et al. A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography. J Chromatogr A. 2014;1360:240-7 pubmed publisher
|
Monzel M, Kuhn M, Bähre H, Seifert R, Schneider E. PDE7A1 hydrolyzes cCMP. FEBS Lett. 2014;588:3469-74 pubmed publisher
|
Biggs J, Boakye P, Ganesan N, Stemkowski P, Lantero A, Ballanyi K, et al. Analysis of the long-term actions of gabapentin and pregabalin in dorsal root ganglia and substantia gelatinosa. J Neurophysiol. 2014;112:2398-412 pubmed publisher
|
Hamdane N, Stefanovsky V, Tremblay M, Németh A, Paquet E, Lessard F, et al. Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body. PLoS Genet. 2014;10:e1004505 pubmed publisher
|
Laourdakis C, Merino E, Neilson A, Cassera M. Comprehensive quantitative analysis of purines and pyrimidines in the human malaria parasite using ion-pairing ultra-performance liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;967:127-33 pubmed publisher
|
Krstulja A, Lettieri S, Hall A, Delepee R, Favetta P, Agrofoglio L. Evaluation of molecularly imprinted polymers using 2',3',5'-tri-O-acyluridines as templates for pyrimidine nucleoside recognition. Anal Bioanal Chem. 2014;406:6275-84 pubmed publisher
|
Massarotti A, Aprile S, Mercalli V, Del Grosso E, Grosa G, Sorba G, et al. Are 1,4- and 1,5-disubstituted 1,2,3-triazoles good pharmacophoric groups?. ChemMedChem. 2014;9:2497-508 pubmed publisher
|
Li S, Zhang H, Wang T, Meng X, Zong Z, Kong D, et al. BAG3 promoted starvation-induced apoptosis of thyroid cancer cells via attenuation of autophagy. J Clin Endocrinol Metab. 2014;99:E2298-307 pubmed publisher
|
Sonawane P, Cho H, Tagde A, Verlekar D, Yu A, Reynolds C, et al. Metabolic characteristics of 13-cis-retinoic acid (isotretinoin) and anti-tumour activity of the 13-cis-retinoic acid metabolite 4-oxo-13-cis-retinoic acid in neuroblastoma. Br J Pharmacol. 2014;171:5330-44 pubmed publisher
|
Godoy V, Banales J, Medina J, Pastor Anglada M. Functional crosstalk between the adenosine transporter CNT3 and purinergic receptors in the biliary epithelia. J Hepatol. 2014;61:1337-43 pubmed publisher
|
Jeong E, Kim Y, Kim H, Shin H, Shin J, Kim K, et al. Glucuronidation of fimasartan, a new angiotensin receptor antagonist, is mainly mediated by UGT1A3. Xenobiotica. 2015;45:10-8 pubmed publisher
|
Stentoft C, Vestergaard M, Løvendahl P, Kristensen N, Moorby J, Jensen S. Simultaneous quantification of purine and pyrimidine bases, nucleosides and their degradation products in bovine blood plasma by high performance liquid chromatography tandem mass spectrometry. J Chromatogr A. 2014;1356:197-210 pubmed publisher
|
Bounedjah O, Desforges B, Wu T, Pioche Durieu C, Marco S, Hamon L, et al. Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules. Nucleic Acids Res. 2014;42:8678-91 pubmed publisher
|
Summers D, DiAntonio A, Milbrandt J. Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons. J Neurosci. 2014;34:9338-50 pubmed publisher
|
van De Sande M, van Buul V, Brouns F. Autism and nutrition: the role of the gut-brain axis. Nutr Res Rev. 2014;27:199-214 pubmed publisher
|
Liu D, Zou X, Gao M, Gu M, Xiao H. Hydrophilic organic/salt-containing aqueous two-phase solvent system for counter-current chromatography: a novel technique for separation of polar compounds. J Chromatogr A. 2014;1356:157-62 pubmed publisher
|
Choi E, Park J, Yoon K, Bae S. Evaluation of the in vitro/in vivo potential of five berries (bilberry, blueberry, cranberry, elderberry, and raspberry ketones) commonly used as herbal supplements to inhibit uridine diphospho-glucuronosyltransferase. Food Chem Toxicol. 2014;72:13-9 pubmed publisher
|
Melemedjian O, Tillu D, Moy J, Asiedu M, Mandell E, Ghosh S, et al. Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Mol Pain. 2014;10:45 pubmed publisher
|
Xie Y, Cai Q, Ren H, Wang L, Xu H, Hong B, et al. NRPS substrate promiscuity leads to more potent antitubercular sansanmycin analogues. J Nat Prod. 2014;77:1744-8 pubmed publisher
|
Higurashi T, Endo H, Uchiyama T, Uchiyama S, Yamada E, Ohkubo H, et al. Conditional knockout of the leptin receptor in the colonic epithelium revealed the local effects of leptin receptor signaling in the progression of colonic tumors in mice. Carcinogenesis. 2014;35:2134-41 pubmed publisher
|
Gottstein Schmidtke S, Duchardt Ferner E, Groher F, Weigand J, Gottstein D, Suess B, et al. Building a stable RNA U-turn with a protonated cytidine. RNA. 2014;20:1163-72 pubmed publisher
|
Soares A, Costa V, Diniz C, Fresco P. Inosine strongly enhances proliferation of human C32 melanoma cells through PLC-PKC-MEK1/2-ERK1/2 and PI3K pathways. Basic Clin Pharmacol Toxicol. 2015;116:25-36 pubmed publisher
|
Yi J, Wang H, Vilela M, Danuser G, Hahn K. Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides. ACS Synth Biol. 2014;3:788-95 pubmed publisher
|
Bae S, Kwon M, Park J, Kim D, Kim D, Kang J, et al. Metabolic drug-drug interaction potential of macrolactin A and 7-O-succinyl macrolactin A assessed by evaluating cytochrome P450 inhibition and induction and UDP-glucuronosyltransferase inhibition in vitro. Antimicrob Agents Chemother. 2014;58:5036-46 pubmed publisher
|
Maier Salamon A, Thalhammer T, Reznicek G, Böhmdorfer M, Zupko I, Hartl A, et al. Cytochrome P450 3A-mediated metabolism of the topoisomerase I inhibitor 9-aminocamptothecin: impact on cancer therapy. Int J Oncol. 2014;45:877-86 pubmed publisher
|
Wu W, Hu N, Zhang Q, Li Y, Li P, Yan R, et al. In vitro glucuronidation of five rhubarb anthraquinones by intestinal and liver microsomes from humans and rats. Chem Biol Interact. 2014;219:18-27 pubmed publisher
|
Mesquita S, Ferreira A, Falcao A, Sousa J, Oliveira T, Correia Neves M, et al. Lipocalin 2 modulates the cellular response to amyloid beta. Cell Death Differ. 2014;21:1588-99 pubmed publisher
|
Arimany Nardi C, Errasti Murugarren E, Minuesa G, Martinez Picado J, Gorboulev V, Koepsell H, et al. Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA-methyltransferase inhibitors. Br J Pharmacol. 2014;171:3868-80 pubmed publisher
|
Higashi E, Ando A, Iwano S, Murayama N, Yamazaki H, Miyamoto Y. Hepatic microsomal UDP-glucuronosyltransferase (UGT) activities in the microminipig. Biopharm Drug Dispos. 2014;35:313-20 pubmed publisher
|
Raman R, Allen S, Goodall E, Kramer S, Ponger L, Heath P, et al. Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions. Neuropathol Appl Neurobiol. 2015;41:201-26 pubmed publisher
|
Ren G, Xie M, Zhang S, Vinovskis C, Chen X, Yu B. Methylation protects microRNAs from an AGO1-associated activity that uridylates 5' RNA fragments generated by AGO1 cleavage. Proc Natl Acad Sci U S A. 2014;111:6365-70 pubmed publisher
|
Zhang T, Wu W, Li D, Xu T, Zhu H, Pan D, et al. Anti-oxidant and anti-apoptotic effects of luteolin on mice peritoneal macrophages stimulated by angiotensin II. Int Immunopharmacol. 2014;20:346-51 pubmed publisher
|
Iwen K, Priewe A, Winnefeld M, Rose C, Siemers F, Rohwedel J, et al. Gluteal and abdominal subcutaneous adipose tissue depots as stroma cell source: gluteal cells display increased adipogenic and osteogenic differentiation potentials. Exp Dermatol. 2014;23:395-400 pubmed publisher
|
Flint M, McMullan L, Dodd K, Bird B, Khristova M, Nichol S, et al. Inhibitors of the tick-borne, hemorrhagic fever-associated flaviviruses. Antimicrob Agents Chemother. 2014;58:3206-16 pubmed publisher
|
Vlčková H, Ježková K, Stětková K, Tomšíková H, Solich P, Novakova L. Study of the retention behavior of small polar molecules on different types of stationary phases used in hydrophilic interaction liquid chromatography. J Sep Sci. 2014;37:1297-307 pubmed publisher
|
Zheng Y, Bae S, Choi E, Park J, Kim S, Jang M, et al. Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition. Food Chem Toxicol. 2014;68:117-27 pubmed publisher
|
Wittmann G, Harney J, Singru P, Nouriel S, Reed Larsen P, Lechan R. Inflammation-inducible type 2 deiodinase expression in the leptomeninges, choroid plexus, and at brain blood vessels in male rodents. Endocrinology. 2014;155:2009-19 pubmed publisher
|
Saez I, Duran J, Sinadinos C, Beltran A, Yanes O, Tevy M, et al. Neurons have an active glycogen metabolism that contributes to tolerance to hypoxia. J Cereb Blood Flow Metab. 2014;34:945-55 pubmed publisher
|
Raj V, Barman T, Kalia V, Purnapatre K, Dube S, G R, et al. A novel ketolide, RBx 14255, with activity against multidrug-resistant Streptococcus pneumoniae. Antimicrob Agents Chemother. 2014;58:4283-9 pubmed publisher
|
Falck E, Begrow F, Verspohl E, Wünsch B. In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist. J Pharm Biomed Anal. 2014;94:36-44 pubmed publisher
|
Gozes I, Iram T, Maryanovsky E, Arviv C, Rozenberg L, Schirer Y, et al. Novel tubulin and tau neuroprotective fragments sharing structural similarities with the drug candidate NAP (Davuentide). J Alzheimers Dis. 2014;40 Suppl 1:S23-36 pubmed publisher
|
Hu N, Mei M, Ruan J, Wu W, Wang Y, Yan R. Regioselective glucuronidation of oxyresveratrol, a natural hydroxystilbene, by human liver and intestinal microsomes and recombinant UGTs. Drug Metab Pharmacokinet. 2014;29:229-36 pubmed
|
Piper M, Blanc E, Leitão Gonçalves R, Yang M, He X, Linford N, et al. A holidic medium for Drosophila melanogaster. Nat Methods. 2014;11:100-5 pubmed publisher
|
Govan J, Young D, Lusic H, Liu Q, Lively M, Deiters A. Optochemical control of RNA interference in mammalian cells. Nucleic Acids Res. 2013;41:10518-28 pubmed publisher
|
Sheng J, Gan J, Soares A, Salon J, Huang Z. Structural insights of non-canonical U*U pair and Hoogsteen interaction probed with Se atom. Nucleic Acids Res. 2013;41:10476-87 pubmed publisher
|
He T, Haapa Paananen S, Kaminskyy V, Kohonen P, Fey V, Zhivotovsky B, et al. Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis. Oncogene. 2014;33:3538-49 pubmed publisher
|
Liu W, Kulkarni K, Hu M. Gender-dependent differences in uridine 5'-diphospho-glucuronosyltransferase have implications in metabolism and clearance of xenobiotics. Expert Opin Drug Metab Toxicol. 2013;9:1555-69 pubmed publisher
|
Xu H, Franks T, Gibson G, Huber K, Rahm N, Strambio de Castillia C, et al. Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay. Retrovirology. 2013;10:70 pubmed publisher
|
Nishimoto A, Jitsuzaki D, Onizuka K, Taniguchi Y, Nagatsugi F, Sasaki S. 4-vinyl-substituted pyrimidine nucleosides exhibit the efficient and selective formation of interstrand cross-links with RNA and duplex DNA. Nucleic Acids Res. 2013;41:6774-81 pubmed publisher
|
Kim J, Xiao H, Bonanno J, Kalyanaraman C, Brown S, Tang X, et al. Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function. Nature. 2013;498:123-6 pubmed publisher
|
Zhou Y, Kierzek E, Loo Z, Antonio M, Yau Y, Chuah Y, et al. Recognition of RNA duplexes by chemically modified triplex-forming oligonucleotides. Nucleic Acids Res. 2013;41:6664-73 pubmed publisher
|
Klein D, Evans K, Hardwick R, Dantzler W, Wright S, Cherrington N. Basolateral uptake of nucleosides by Sertoli cells is mediated primarily by equilibrative nucleoside transporter 1. J Pharmacol Exp Ther. 2013;346:121-9 pubmed publisher
|
Kim J, Almo S. Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC. BMC Struct Biol. 2013;13:5 pubmed publisher
|
Liu R, Lin G, Xu H. An efficient method for dorsal root ganglia neurons purification with a one-time anti-mitotic reagent treatment. PLoS ONE. 2013;8:e60558 pubmed publisher
|
Baek I, Lee B, Kim M, Kwon K. Pharmacokinetic analysis of doxifluridine and its metabolites, 5-fluorouracil and 5-fluorouridine, after oral administration in beagle dogs. Eur J Drug Metab Pharmacokinet. 2013;38:295-9 pubmed publisher
|
Shih Y, Yang Y, Lin C, Chien T. Synthesis of 6-alkyluridines from 6-cyanouridine via zinc(II) chloride-catalyzed nucleophilic substitution with alkyl Grignard reagents. J Org Chem. 2013;78:4027-36 pubmed publisher
|
Takahashi Y, Igarashi M, Miyake T, Soutome H, Ishikawa K, Komatsuki Y, et al. Novel semisynthetic antibiotics from caprazamycins A-G: caprazene derivatives and their antibacterial activity. J Antibiot (Tokyo). 2013;66:171-8 pubmed publisher
|
Tsochatzis E, Tzimou Tsitouridou R, Menkissoglu Spiroudi U, Karpouzas D, Katsantonis D. Laboratory and field dissipation of penoxsulam, tricyclazole and profoxydim in rice paddy systems. Chemosphere. 2013;91:1049-57 pubmed publisher
|
Li Q, Wang L, Xie Y, Wang S, Chen R, Hong B. SsaA, a member of a novel class of transcriptional regulators, controls sansanmycin production in Streptomyces sp. strain SS through a feedback mechanism. J Bacteriol. 2013;195:2232-43 pubmed publisher
|
Fu Y, He Y, Hou H, Zhu W, Li H, Wu C, et al. 2,2'-Anhydro-1-(3',5'-di-O-acetyl-β-D-arabinofuranosyl)uracil, a cyclouridine nucleoside with a C4'-endo furanosyl conformation. Acta Crystallogr C. 2013;69:282-4 pubmed publisher
|
Cansev M, Minbay Z, Goren B, Yaylagul E, Cetinkaya M, Koksal N, et al. Neuroprotective effects of uridine in a rat model of neonatal hypoxic-ischemic encephalopathy. Neurosci Lett. 2013;542:65-70 pubmed publisher
|
Nilsen T. Detecting RNA-protein interactions by photocross-linking using RNA molecules containing uridine analogs. Cold Spring Harb Protoc. 2013;2013: pubmed publisher
|
Haarer B, Mi Mi L, Cho J, Cortese M, Viggiano S, Burke D, et al. Actin dosage lethality screening in yeast mediated by selective ploidy ablation reveals links to urmylation/wobble codon recognition and chromosome stability. G3 (Bethesda). 2013;3:553-61 pubmed publisher
|
Crandall I, Wasilewski E, Bello A, Mohmmed A, Malhotra P, Pai E, et al. Antimalarial activities of 6-iodouridine and its prodrugs and potential for combination therapy. J Med Chem. 2013;56:2348-58 pubmed publisher
|
Scott D, Norbury C. RNA decay via 3' uridylation. Biochim Biophys Acta. 2013;1829:654-65 pubmed publisher
|
Jenkins J, Agrawal A, Gupta A, Green M, Kielkopf C. U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res. 2013;41:3859-73 pubmed publisher
|
Wang X, Suzawa T, Miyauchi T, Zhao B, Yasuhara R, Anada T, et al. Synthetic octacalcium phosphate-enhanced reparative dentine formation via induction of odontoblast differentiation. J Tissue Eng Regen Med. 2015;9:1310-20 pubmed publisher
|
Hashimi H, Zimmer S, Ammerman M, Read L, Lukes J. Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex. Trends Parasitol. 2013;29:91-9 pubmed publisher
|
Moss R. Pitfalls of drug development: lessons learned from trials of denufosol in cystic fibrosis. J Pediatr. 2013;162:676-80 pubmed publisher
|
Härtel B, Zehrmann A, Verbitskiy D, van der Merwe J, Brennicke A, Takenaka M. MEF10 is required for RNA editing at nad2-842 in mitochondria of Arabidopsis thaliana and interacts with MORF8. Plant Mol Biol. 2013;81:337-46 pubmed publisher
|
Komor R, Pastuch Gawołek G, Sobania A, Jadwiński M, Szeja W. Application of different alpha-1-thioglycosides preparation methods in synthesis of 5-nitro-2-pyridyl 1-thioglycosides substrates in synthesis of conjugates with uridine moiety. Part I. Acta Pol Pharm. 2012;69:1259-69 pubmed
|
Grec M, Swierk P, Pastuch Gawołek G, Szeja W. Synthesis of galactothiophosphoesters of uridine and preliminary tests to evaluate their activity against selected glycosyltransferases. Acta Pol Pharm. 2012;69:1248-58 pubmed
|
Colpitts C, Ustinov A, Epand R, Epand R, Korshun V, Schang L. 5-(Perylen-3-yl)ethynyl-arabino-uridine (aUY11), an arabino-based rigid amphipathic fusion inhibitor, targets virion envelope lipids to inhibit fusion of influenza virus, hepatitis C virus, and other enveloped viruses. J Virol. 2013;87:3640-54 pubmed publisher
|
Goryanova B, Spong K, Amyes T, Richard J. Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates. Biochemistry. 2013;52:537-46 pubmed publisher
|
Jobert L, Skjeldam H, Dalhus B, Galashevskaya A, Vågbø C, Bjørås M, et al. The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control. Mol Cell. 2013;49:339-45 pubmed publisher
|
Jones M, Blahna M, Kozlowski E, Matsuura K, Ferrari J, Morris S, et al. Zcchc11 uridylates mature miRNAs to enhance neonatal IGF-1 expression, growth, and survival. PLoS Genet. 2012;8:e1003105 pubmed publisher
|
Wang L, Xie Y, Li Q, He N, Yao E, Xu H, et al. Draft genome sequence of Streptomyces sp. strain SS, which produces a series of uridyl peptide antibiotic sansanmycins. J Bacteriol. 2012;194:6988-9 pubmed publisher
|
Ko Y, Storoniak P, Wang H, Bowen K, Rak J. Photoelectron spectroscopy and density functional theory studies on the uridine homodimer radical anions. J Chem Phys. 2012;137:205101 pubmed publisher
|
Hilcenko C, Simpson P, Finch A, Bowler F, Churcher M, Jin L, et al. Aberrant 3' oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia. Blood. 2013;121:1028-38 pubmed publisher
|
Ali J, Creek D, Burgess K, Allison H, Field M, Maser P, et al. Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines. Mol Pharmacol. 2013;83:439-53 pubmed publisher
|
Aphasizhev R, Aphasizheva I. Uridine insertion/deletion editing in trypanosomes: a playground for RNA-guided information transfer. Wiley Interdiscip Rev RNA. 2011;2:669-85 pubmed publisher
|
Lightfoot Y, Chen J, Mathews C. Role of the mitochondria in immune-mediated apoptotic death of the human pancreatic β cell line βLox5. PLoS ONE. 2011;6:e20617 pubmed publisher
|
Yamamoto T, Koyama H, Kurajoh M, Shoji T, Tsutsumi Z, Moriwaki Y. Biochemistry of uridine in plasma. Clin Chim Acta. 2011;412:1712-24 pubmed publisher
|
Dobolyi A, Juhasz G, Kovacs Z, Kardos J. Uridine function in the central nervous system. Curr Top Med Chem. 2011;11:1058-67 pubmed
|
Wurtman R, Cansev M, Sakamoto T, Ulus I. Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase formation of brain synapses. Nutr Rev. 2010;68 Suppl 2:S88-101 pubmed publisher
|
René O, Alix J. Late steps of ribosome assembly in E. coli are sensitive to a severe heat stress but are assisted by the HSP70 chaperone machine. Nucleic Acids Res. 2011;39:1855-67 pubmed publisher
|
Fourches D, Barnes J, Day N, Bradley P, Reed J, Tropsha A. Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chem Res Toxicol. 2010;23:171-83 pubmed publisher
|
Roy A, Lunn F, Bearne S. Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids. Bioorg Med Chem Lett. 2010;20:141-4 pubmed publisher
|
Lopez Gresa M, Cabedo N, González Mas M, Ciavatta M, Avila C, Primo J. Terretonins E and F, inhibitors of the mitochondrial respiratory chain from the marine-derived fungus Aspergillus insuetus (#). J Nat Prod. 2009;72:1348-51 pubmed publisher
|
Singh K, Ayyasamy V, Owens K, Koul M, Vujcic M. Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesis. J Hum Genet. 2009;54:516-24 pubmed publisher
|
Bailey C. Orotic aciduria and uridine monophosphate synthase: a reappraisal. J Inherit Metab Dis. 2009;32 Suppl 1:S227-33 pubmed publisher
|
Wurtman R, Cansev M, Ulus I. Synapse formation is enhanced by oral administration of uridine and DHA, the circulating precursors of brain phosphatides. J Nutr Health Aging. 2009;13:189-97 pubmed
|
Wurtman R, Cansev M, Sakamoto T, Ulus I. Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain. World Rev Nutr Diet. 2009;99:71-96 pubmed publisher
|
Masuho I, Mototani Y, Sahara Y, Asami J, Nakamura S, Kozasa T, et al. Dynamic expression patterns of G protein-regulated inducer of neurite outgrowth 1 (GRIN1) and its colocalization with Galphao implicate significant roles of Galphao-GRIN1 signaling in nervous system. Dev Dyn. 2008;237:2415-29 pubmed publisher
|
Korshun V, Stetsenko D, Gait M. Uridine 2'-carbamates: facile tools for oligonucleotide 2'-functionalization. Curr Protoc Nucleic Acid Chem. 2004;Chapter 4:Unit 4.21 pubmed publisher
|
Hatano A, Harano A, Takigawa Y, Naramoto Y, Toda K, Nakagomi Y, et al. Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase. Bioorg Med Chem. 2008;16:3866-70 pubmed publisher
|
Zander J, Besier S, Saum S, Dehghani F, Loitsch S, Brade V, et al. Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus. Infect Immun. 2008;76:1333-9 pubmed
|
Murakami E, Bao H, Ramesh M, McBrayer T, Whitaker T, Micolochick Steuer H, et al. Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase. Antimicrob Agents Chemother. 2007;51:503-9 pubmed
|
Cansev M. Uridine and cytidine in the brain: their transport and utilization. Brain Res Rev. 2006;52:389-97 pubmed
|
Walker U, Venhoff N. Uridine in the prevention and treatment of NRTI-related mitochondrial toxicity. Antivir Ther. 2005;10 Suppl 2:M117-23 pubmed
|
Yamamoto I. [Studies on the structure-activity relationship of allyl substituted oxopyrimidines searching for the novel antagonist or agonist of barbiturates to the sleep mechanism based on the uridine receptor theory--barbituric acid to uridine (part I)]. Yakugaku Zasshi. 2005;125:73-120 pubmed
|
Cao D, Pizzorno G. Uridine phosophorylase: an important enzyme in pyrimidine metabolism and fluoropyrimidine activation. Drugs Today (Barc). 2004;40:431-43 pubmed
|
Simpson L, Sbicego S, Aphasizhev R. Uridine insertion/deletion RNA editing in trypanosome mitochondria: a complex business. RNA. 2003;9:265-76 pubmed
|
Fornai F, Busceti C, Ferrucci M, Lazzeri G, Ruggieri S. Is there a role for uridine and pyrimidine nucleosides in the treatment of vascular dementia?. Funct Neurol. 2002;17:93-9 pubmed
|
Pizzorno G, Cao D, Leffert J, Russell R, Zhang D, Handschumacher R. Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update. Biochim Biophys Acta. 2002;1587:133-44 pubmed
|
Kimura T, Ho I, Yamamoto I. Uridine receptor: discovery and its involvement in sleep mechanism. Sleep. 2001;24:251-60 pubmed
|
Chester A, Scott J, Anant S, Navaratnam N. RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA. Biochim Biophys Acta. 2000;1494:1-13 pubmed
|
Estevez A, Simpson L. Uridine insertion/deletion RNA editing in trypanosome mitochondria--a review. Gene. 1999;240:247-60 pubmed
|
Connolly G, Duley J. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999;20:218-25 pubmed
|